• Journal of The Korean Society of Clinical Toxicology
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• v.4 no.2
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• pp.180-186
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• 2006

The various species of aconitum contain diterpene (C-20) and norditerpene (C-19) forms of the natural alkaloid aconitine that cause neurologic, gastrointestinal, cardiovascular symptoms. In chinese medicine, these plants has been used as drugs to treat pain, dyspepsia, cerebrovascular disease, and so on. Because the therapeutic window is narrow, poisoning may occur from unintentional exposure, with a variety of toxic effects such as arrhythmia, hypotension, paresthesia, paralysis, nausea, vomiting, and abdominal pain. Aconitine-containing folk remedies are widely used in Korea. We encountered two cases of ventricular arrhythmia in patients who ingested tablets, known as 'Wha-Pung-Dan' made with aconitine extracts and were subsequently admitted to the ED. A 42 year-old man who took 35 tablets presented with ventricualr tarchycardia, and 40 year-old woman who took 40 tablets showed premature ventricular contractions. Both patients were discharged normally without any complications after three days.

• Journal of Plant Biotechnology
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• v.36 no.3
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• pp.224-229
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• 2009

Human lactoferrin is an iron-binding glycoprotein with many biological activities, including the protection against microbial and virus infection and stimulation of the immune system. We introduced a human lactoferrin (hLf) cDNA under the control of 35S promoter into sweet potato by particle bombardment. Transgenic plants were regenerated via somatic embryogenesis. Transgenic plants were produced typical tuberous roots in soil. PCR, Southern and northern analyses confirmed that the hLf cDNA was incorporated into the plant genome and was properly expressed in plants. Western blot analysis showed that the 80 kDa full length hLf protein was produced in transgenic tuberous roots. Overall results indicated that sweet potato would be an excellent host to produce human therapeutic proteins.

• The Korean Journal of Applied Statistics
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• v.23 no.2
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• pp.249-261
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• 2010

Long-term forecasting of seasonal time series is critical in many applications such as planning business strategies and resolving possible problems of a business company. Unlike the traditional approach that depends solely on dynamic models, Li and Hinich (2002) introduced a combination of stochastic dynamic modeling with filter bank approach for forecasting seasonal patterns using highly coherent(High-C) waveforms. We modify the filter selection and forecasting procedure on wavelet domain to be more feasible and compare the resulting predictor with one that obtained from the wavelet variance estimation method. An improvement over other seasonal pattern extraction and forecasting methods based on such as wavelet scalogram, Holt-Winters, and seasonal autoregressive integrated moving average(SARIMA) is shown in terms of the prediction error. The performance of the proposed method is illustrated by a simulation study and an application to the real stock price data.

• Journal of the Korean Wood Science and Technology
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• v.42 no.2
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• pp.214-221
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• 2014

The deterioration in wood by the brown-rot fungus (Fomitopsispalustris) and the white-rot fungus (Trametesversicolor) were measured using ultrasonic velocity. Those were used for the decay exposure and 4 wood species of wood as the test specimens, Pinusdensiflora, Larixkaempferi, Pinuskoraiensis and Pinusrigida, were chosen with both the brown- and white-rot culture petridish during 12 weeks. After 12 weeks, the decrease rate of ultrasonic velocity was measured at 10~15%. In both brown- and white-rot exposure experiments, P. rigida showed significant decrease in ultrasonic velocity (20%), L. kaempferi on the other hand did not show decrease in ultrasonic velocity. After the fungal exposure experiment, the inside of specimens was investigated by computer tomography (C/T). After C/T investigation, bending tests were performed.

• Proceedings of the Korean Society of Toxicology Conference
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• 2001.10a
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• pp.198-198
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• 2001

No report has been addressed to the CYP isoforms catalyzing chlorpropamide, a structural analogue of tolbutamide. To evaluate enzyme(s) mediating formation of 2-hydroxycWorpropamide, a major metabolite and identified by LC/Mass and NMR, incubation studies using human liver microsomes and cDNA expressed CYP were performed on the presence or absence of selective inhibitors of each CYP isoform. (omitted)

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.13 no.10
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• pp.1017-1024
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• 2001

The optimum shape of header part in a PFHE (parallel-flow heat exchanger) is studied. The optimal values of each geometric parameter are proposed according to their order of influence with varying the four important parameters (the injection angle of working fluid ($\Theta$), the shape of inlet(S), the location of inlet ($y_c/D_{in}$) and the height of the protruding flat tube ( $y_{b/}$ $D_{in}$ )). The optimal geometric parameters are as follows:$\Theta= -21^{\circ}C,\; S=Type\; A \;an\;y_b/D_{in}$/=0. The heat transfer rate of the optimum model, compared to that of the reference model, is increased by about 55%. The optimal geometric parameters ran be applicable to the Reynolds number ranging from 5,000 to 20,000.0.

• International Journal of Oral Biology
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• v.35 no.4
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• pp.145-151
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• 2010

Periodontitis is an inflammatory disorder of the periodontium and is characterized by destruction of the tooth supporting tissues, mediated by the upregulation of synthesis and release of a variety of pro-inflammatory factors. Inflammatory cytokines and prostaglandins upregulate RANKL and its subsequent binding to RANK stimulates osteoclast formation, resorption activity, and survival. In our present study, we investigated the effects of HP08-0111, composed of Coptis japonica (Thunb.) Makino, vitamin C and vitamin E, upon inflammatory responses, osteoclastogenesis and alveolar bone loss. HP08-0111 decreased the expression of IL-1$\beta$ and COX2 on LPS-induced RAW 264.7 cells and inhibited osteoclast-specific genes such as c-Fos, MMP-9, and TRAP. HP08-0111 also exhibited protective effects against alveolar bone loss in rats with ligature-induced periodontitis. Our results suggest that HP08-0111 is potentially an important therapeutic tool for the treatment of disorders associated with bone loss such as periodontitis.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2001.10a
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• pp.749-752
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• 2001

In this paper, the channel access algorithm for the AIS is analyzed and the design of the functional modules is presented. The function of RATDMA, ITDMA, FATDMA, and SOTDMA algorithm defined by ITU-R M.1371 specification is analyzed. Each TDMA algorithm is designed as a modularized function. In order to verify the function of designed channel access algorithm, the algorithm is implemented using C language and simulated on the PC environment. The simulation results show that the algorithm ran properly allocate a transmission slot and is satisfied with the requirements of the specification.

• Korean Journal of Crystallography
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• v.8 no.2
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• pp.124-126
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• 1997

The comples of [Ni(L)](ClO4)2 (L:3,5,10,12-tetramethyl-1,4,8,12-tetraazacyclotetradecane), C14H32Cl2N4NiO8, has a NiN4 square planar geometry and adopts a thermodynamically most stable trans-III conformation.

• Electronics and Telecommunications Trends
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• v.31 no.5
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• pp.80-89
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• 2016

현재 이동통신 분야에서는 5세대(5th Generation: 5G) 이동통신 표준화 작업이 한창 진행 중이며, 그 표준화 현황을 살펴보기 위하여 대표적인 국제 표준화 단체인 ITU-R에서의 활동 및 3GPP에서의 활동을 살펴보고자 한다. 최근 ITU-R WP 5D에서는 IMT-2020으로 명명되는 5세대 이동통신 비전 문서를 토대로 기술 요구사항 및 평가 기준 마련을 위한 작업이 수행되고 있으며, 3GPP의 TSG SA, RAN 및 하위 WG에서는 관련 상위 레벨 요구사항 정립 및 무선 구간에서의 기술적인 SI 논의가 수행되고 있다. 본고에서는 위 두 표준화 활동을 위주로 5G 이동통신에 대한 현황을 기술한다.