• Title/Summary/Keyword: C-Arm

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Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling

  • Krishnan, Jayalakshmi;Choi, Sang-Dun
    • Genomics & Informatics
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    • v.10 no.3
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    • pp.153-166
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    • 2012
  • A variety of ligands differ in their capacity to bind the receptor, elicit gene expression, and modulate physiological responses. Such receptors include Toll-like receptors (TLRs), which recognize various patterns of pathogens and lead to primary innate immune activation against invaders, and G-protein coupled receptors (GPCRs), whose interaction with their cognate ligands activates heterotrimeric G proteins and regulates specific downstream effectors, including immuno-stimulating molecules. Once TLRs are activated, they lead to the expression of hundreds of genes together and bridge the arm of innate and adaptive immune responses. We characterized the gene expression profile of Toll-like receptor 4 (TLR4) in RAW 264.7 cells when it bound with its ligand, 2-keto-3-deoxyoctonate (KDO), the active part of lipopolysaccharide. In addition, to determine the network communications among the TLR, Janus kinase (JAK)/signal transducer and activator of transcription (STAT), and GPCR, we tested RAW 264.7 cells with KDO, interferon-${\beta}$, or cAMP analog 8-Br. The ligands were also administered as a pair of double and triple combinations.

The Effect of Thoracic Posture on The Shoulder Range of Motion and on Three-Dimensional Scapular Kinematics (흉추 자세가 견관절 가동범위와 3차원적 견갑골 운동학에 미치는 영향)

  • Park, Seung-Kyu;Han, Song-E
    • Korean Journal of Applied Biomechanics
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    • v.20 no.2
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    • pp.197-204
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    • 2010
  • Scapular position and motion are essential for normal upper limb mobility; Further, the posture of patients with thoracic kyphosis is related to shoulder girdle function and disorder. The purpose of this study was to examine the effects of thoracic posture on the shoulder range of motion and on three-dimensional scapular kinematics. Thirty healthy subjects performed right-arm abduction along the frontal plane while standing in both erect and in slouched trunk posture. The scapular position and rotation, and shoulder and thoracic angles were recorded using a motion analysis system. The scapular upward rotation and internal rotation were significantly altered according to postural tatiges; however, scapular tilt was not affected. Shoulder angle was significantly decreased in the slouched posture as c rpared to tatt in the erect posture. Thus, a slouched posture(thoracic kyphosis) significantly affects the shoulder range of motion and scapular kinematics during shoulder abduction in the frontal plane.

Thermal and Dynamical Evolution of a Gaseous Medium and Star Formation in Disk Galaxies

  • Kim, Chang-Goo;Kim, Woong-Tae;Ostriker, Eve C.
    • The Bulletin of The Korean Astronomical Society
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    • v.36 no.1
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    • pp.54.1-54.1
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    • 2011
  • Formation of self-gravitating gas clouds and hence stars in galaxies is a consequence of both thermal and dynamical evolution of a gaseous medium. Using hydrodynamics simulations including cooling and heating explicitly, we follow simultaneously thermal and dynamical evolution of galactic gas disks to study dynamics and structures of galactic spiral shocks with thermal instability and regulation of the star formation rates (SFRs). We first perform one-dimensional simulations in direction perpendicular to spiral arms. The multiphase gas flows across the arm soon achieve a quasi-steady state characterized by transitions from warm to cold phases at the shock and from cold to warm phases in the postshock expansion zone, producing a substantial fraction of intermediate-temperature gas. Next, we allow a vertical degree of freedom to model vertically stratified disks. The shock front experiences unsteady flapping motions, driving a significant amount of random gas motions, and self-gravity promotes formation of bound clouds inside spiral arms. Finally, we include the star formation feedback in both mechanical (due to supernova explosion) and radiative (due to FUV heating by young stars) forms in the absence of spiral arms. At saturation, gravitationally bound clouds form via thermal and gravitational instabilities, which are compensated by disruption via supernova explosions. We find that the FUV heating regulates the SFRs when gas surface density is low, confirming the prediction of the thermal and dynamical equilibrium model of Ostriker et al. (2010) for star formation regulation.

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An Ergonomics Study of Clothing in an Environmental Aspect - Effects of the Sleeve and Pants Length to Skin Temperature, Thermal Sensation and Feeling of Restriction - (환경요소면으로 본 의복의 인간공학적 연구 (II) - 의복의 소매길이와 바지길이가 피부온 및 감각에 미치는 영향 -)

  • 이전숙
    • Journal of the Korean Home Economics Association
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    • v.20 no.4
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    • pp.69-81
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    • 1982
  • Eight female subjects aged between 19 and 21 years old were used to compare 4 kinds of sleeves and pants length estimates of the effect of skin temperatures and thermal and restricted sensation. The subjects were exposed to climatic conditions between 23$\pm$$1^{\circ}C$, RH 65$\pm$5% while repose and exercise. Mean skin temperature became higher according to the sleeves and pants length. 4 kinds of shirts and pants always covered back and chest, but skin temperature of these parts are affected by the length of clothes. Thigh, uppar arm and shin which are covered or uncovered according to the lengh of the sleeve and pants, skin temperature of these parts became higher when convered with clothes than when uncovered. The subjects ballots warmer and more restricted sensation after exercise than after repose and when wear the long sleeved shirts and slacks that when wear the no sleeve shirts and short shorts. In conclusion, three quarter sleeved shirts and pedal pushers are recommended for the rest clothes and no sleeved shirts and shorts for the sports wear under the preceding conditions.

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The Study on the Fitness Evaluation of the Standard Bodice and Sleeve Block for Young Women's Knitwear (여성용 Knit Bodice와 Sleeve Block의 치수적합성에 관한 연구)

  • 허은영
    • Journal of the Korean Home Economics Association
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    • v.41 no.7
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    • pp.185-200
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    • 2003
  • The purpose of this study was to investigate the fitness using the draft method to develop moderate-stretch knit block pattern for young women in Korea. The subjects were three women within the range of the ages from 18 to 24 showing the average body figures. In this study, 4 different patterns were drafted for the moderate stretch knitted fabrics, that were categorised into two different types. The first type of these was made up for kilted fabrics and the other was initially drafted for woven fabrics and altered for knitted materials afterward. The major findings derived from this investigation were as follows; 1. According to each sensory evaluation for the appearance test on fitness, knit block patterns A and D were the better than the rest of them. 2. Knit block patterns A and D with higher evaluation scores were drafted with body size measurements except the waist line, whereas patterns B and C with relatively lower scores were produced including the smaller ease amounts than the woven block pattern. 3. To see the results of the functional test based on the designed ten motions for this experiment, knit block patterns A and B were concluded as better than the rest of them. In addition, concerning the arm liking motions, pattern B was scored as the best among the developed patterns.

Monitoring System with PLC I/O for Car Parking Lot (Car Parking Lot 모니터링 시스템)

  • Lee, Seong-Jae;Kim, Jae-Yang
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2007.06a
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    • pp.511-512
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    • 2007
  • The monitoring system has won acceptance as a premium mark that identifies the highest standard of product quality in advanced industry. The TOP features with multi-I/O ports and VGA & RCA TV-out ports supporting mirroring & multiple dual-display modes by windows 0/5. With the choice of versatile stands, panel mount, or VESA wall-mount swing arm and connecting to modem. Wireless keyboard, Customer Display and Card Reader, is your idea Panel system for the application of TOP(Touch Operation Pannel), KIOSK, or Office / Factory Automation. TOP is the hardware and software product that transacts all kind of functions for advanced technology equipment to button, switch, voice and graph etc so that let consumer use easily Industrial HMI System Touch Panel. System characteristics: Easy of use and flexibility to the user, Present a high value solution and advanced function for many Application, Factory Automation, Office Automation, Building Automation System, Information Service System, etc. Analog Touch - 2MB Flash Memory for Saving Screen Data - RS-232C/422 Serial Port - Multi Language Support.

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A Study on Modeling of Pneumatic System for an IDC Device (IDC장치에 대한 공압시스템의 모델링에 관한 연구)

  • Nguyen, C.T.;Le, Q.H.;Jeong, Y.M.;Yang, S.Y.
    • Journal of Drive and Control
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    • v.12 no.3
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    • pp.11-17
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    • 2015
  • An intelligent deburring control (IDC) device is used to control the constant force for a deburring tool mounted on the end-effector of a robotic arm. This device maintains a constant contact force between the deburring tool and the workpiece in order to provide a good deburring performance. In this paper, we build a mathematical model in Matlab/Simulink to estimate the force control mechanism of the pneumatic system for the IDC device. The Simulink blocks are built for each separate part and are linked into an integrated simulation system. Such a model also relies on the effects of the flow rate through the valve, air compressibility in the cylinder, and time delay in the pressure valve. The results of the simulation are compared to a simple experiment in which convenient math modeling is performed. These results are then used to optimize the mechanical design and to develop a force control algorithm for the pneumatic cylinder.

On low cost model-based monitoring of industrial robotic arms using standard machine vision

  • Karagiannidisa, Aris;Vosniakos, George C.
    • Advances in robotics research
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    • v.1 no.1
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    • pp.81-99
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    • 2014
  • This paper contributes towards the development of a computer vision system for telemonitoring of industrial articulated robotic arms. The system aims to provide precision real time measurements of the joint angles by employing low cost cameras and visual markers on the body of the robot. To achieve this, a mathematical model that connects image features and joint angles was developed covering rotation of a single joint whose axis is parallel to the visual projection plane. The feature that is examined during image processing is the varying area of given circular target placed on the body of the robot, as registered by the camera during rotation of the arm. In order to distinguish between rotation directions four targets were used placed every $90^{\circ}$ and observed by two cameras at suitable angular distances. The results were deemed acceptable considering camera cost and lighting conditions of the workspace. A computational error analysis explored how deviations from the ideal camera positions affect the measurements and led to appropriate correction. The method is deemed to be extensible to multiple joint motion of a known kinematic chain.

Spiral Arm Features in Disk Galaxies: A Density-Wave Theory

  • Kim, Yonghwi;Ho, Luis C.
    • The Bulletin of The Korean Astronomical Society
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    • v.44 no.1
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    • pp.34.2-34.2
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    • 2019
  • Several observational results show a tighter pitch angle at wavelengths of optical and near-infrared than those that are associated with star formation, which is in agreement with the prediction of the density wave theory. In my recent numerical studies, the dependence of the shock positions relative to the potential minima is due to the tendency that stronger shocks form farther downstream. This causes a systematic variation of the perpendicular Mach number, with radius and makes the pitch angle of the gaseous arms smaller than that of the stellar arms, which supports the prediction of the density-wave theory, independently. However, some observations still give controversial results which show similar pitch angles at wavelengths, and there is no statistical study comparing observations and numerical models directly. By analyzing optical image of disk galaxies in the Carnegie-Irvine Galaxy Survey (CGS), I measured the physical values of stellar and gaseous arms such as their strength, length, and pitch angles. For direct comparison with numerical results, I analyzed more than 30 additional numerical models with varying the initial parameters in model galaxies. In this talk, I will present results both of observational and numerical samples and discuss the physical properties of spiral structures based on the density-wave theory.

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