• 제목/요약/키워드: C/D domain

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Inter-Domain Signal Transmission within the Phytochromes

  • Song, Pill-Soon
    • BMB Reports
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    • v.32 no.3
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    • pp.215-225
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    • 1999
  • Phytochromes (with gene family members phyA, B, C, D, and E) are a wavelength-dependent light sensor or switch for gene regulation that underscore a number of photo responsive developmental and morphogenic processes in plants. Recently, phytochrome-like pigment proteins have also been discovered in prokaryotes, possibly functioning as an auto-phosphorylating/phosphate-relaying two-component signaling system (Yeh et al., 1997). Phytochromes are photochromically convertible between the light sensing Pr and regulatory active Pfr forms. Red light converts Pr to Pfr, the latter having a "switch-on" conformation. The Pfr form triggers signal transduction pathways to the downstream responses including the expression of photosynthetic and other growth-regulating genes. The components involved in and the molecular mechanisms of the light signal transduction pathways are largely unknown, although G-proteins, protein kinases, and secondary messengers such as $Ca^{2+}$ ions and cGMP are implicated. The 124-127 kDa phytochromes form homodimeric structures. The N-terminal half contains the tetrapyrrolic phytochromobilin for red/far-red light absorption. The C-terminal half includes both a dimerization motif and regulatory box where the red light signal perceived by the chromophore-domain is recognized and transduced to initiate the signal transduction cascade. A working model for the inter-domain signal communication within the phytochrome molecule is proposed in this Review.

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Phenomenological Analysis of Piezoelectric Properties in 0.88Pb(Zn1/3Nb2/3)O3−0.12PbTiO3 Single Crystals with an Engineering Domain Configuration

  • Ha, Jong-Yoon;Kim, Jin-Sang;Jeong, Dae-Yong;Kim, Hyun-Jai;Yoon, Seok-Jin
    • Journal of the Korean Ceramic Society
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    • v.45 no.3
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    • pp.139-141
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    • 2008
  • The piezoelectric properties of tetragonal 0.88Pb$(Zn_{1/3}Nb_{2/3)O_3-0.12PbTiO_3$ single crystals are characterized along the <111> direction, which composed the engineering domain configuration in the tetragonal phase. The <111>-oriented crystal possessed smaller $d_{33}$ values compared to the crystal along the <001> spontaneous polarization direction. Based on phenomenological theory, it is shown that the engineering domain configuration does not enhance the piezoelectric constant in tetragonal 0.88Pb$(Zn_{1/3}Nb_{2/3)O_3-0.12PbTiO_3$ single crystals. In addition, the electrostrictive coefficients of $Q_{12}=-0.03706m^4/C^2,\;Q_{11}=0.10765m^4/C^2,\;and\;Q_{44}=0.02020m^4/C^2$ of tetragonal 0.88PZN-0.12PT single crystals were calculated.

GRADED PRIMITIVE AND INC-EXTENSIONS

  • Hamdi, Haleh;Sahandi, Parviz
    • Communications of the Korean Mathematical Society
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    • v.33 no.2
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    • pp.397-408
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    • 2018
  • It is well-known that quasi-$Pr{\ddot{u}}fer$ domains are characterized as those domains D, such that every extension of D inside its quotient field is a primitive extension and that primitive extensions are characterized in terms of INC-extensions. Let $R={\bigoplus}_{{\alpha}{{\in}}{\Gamma}}$ $R_{\alpha}$ be a graded integral domain graded by an arbitrary torsionless grading monoid ${\Gamma}$ and ${\star}$ be a semistar operation on R. The main purpose of this paper is to give new characterizations of gr-${\star}$-quasi-$Pr{\ddot{u}}fer$ domains in terms of graded primitive and INC-extensions. Applications include new characterizations of UMt-domains.

Second-order wave radiation by multiple cylinders in time domain through the finite element method

  • Wang, C.Z.;Mitra, S.;Khoo, B.C.
    • Ocean Systems Engineering
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    • v.1 no.4
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    • pp.317-336
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    • 2011
  • A time domain finite element based method is employed to analyze wave radiation by multiple cylinders. The nonlinear free surface and body surface boundary conditions are satisfied based on the perturbation method up to the second order. The first- and second-order velocity potential problems at each time step are solved through a finite element method (FEM). The matrix equation of the FEM is solved through an iteration and the initial solution is obtained from the result at the previous time step. The three-dimensional (3D) mesh required is generated based on a two-dimensional (2D) hybrid mesh on a horizontal plane and its extension in the vertical direction. The hybrid mesh is generated by combining an unstructured grid away from cylinders and two structured grids near the cylinder and the artificial boundary, respectively. The fluid velocity on the free surface and the cylinder surface are calculated by using a differential method. Results for various configurations including two-cylinder and four-cylinder cases are provided to show the mutual influence due to cylinders on the first and second waves and forces.

NOTES ON CARLESON TYPE MEASURES ON BOUNDED SYMMETRIC DOMAIN

  • Choi, Ki-Seong
    • Communications of the Korean Mathematical Society
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    • v.22 no.1
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    • pp.65-74
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    • 2007
  • Suppose that $\mu$ is a finite positive Borel measure on bounded symmetric domain $\Omega{\subset}\mathbb{C}^n\;and\;\nu$ is the Euclidean volume measure such that $\nu(\Omega)=1$. Suppose 1 < p < $\infty$ and r > 0. In this paper, we will show that the norms $sup\{\int_\Omega{\mid}k_z(w)\mid^2d\mu(w)\;:\;z\in\Omega\}$, $sup\{\int_\Omega{\mid}h(w)\mid^pd\mu(w)/\int_\Omega{\mid}h(w)^pd\nu(w)\;:\;h{\in}L_a^p(\Omega,d\nu),\;h\neq0\}$ and $$sup\{\frac{\mu(E(z,r))}{\nu(E(z,r))}\;:\;z\in\Omega\}$$ are are all equivalent. We will also show that the inclusion mapping $ip\;:\;L_a^p(\Omega,d\nu){\rightarrow}L^p(\Omega,d\mu)$ is compact if and only if lim $w\rightarrow\partial\Omega\frac{\mu(E(w,r))}{\nu(E(w,r))}=0$.

Analysis of Human O-GlcNAcase Gene and the Expression of the Recombinant Gene. (사람의 O-linked N-acetyl-$\beta$-D-glucosaminidase 유전자의 분석과 재조합 발현)

  • 강대욱;서현효
    • Korean Journal of Microbiology
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    • v.40 no.2
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    • pp.87-93
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    • 2004
  • Dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) on Ser and Thr residues is ubiquitous in higher eukaryotes. And this modification may serve as a signaling mod-ification analogous to protein phosphorylation. Addition and cleavage of O-GlcNAc are catalyzed by O-linked GlcNAc transferase (OGT) and O-linked N-acety1glucosaminidase (O-GlcNAcase), respectively. Two types of human O-GlcNAcase gene were cloned and expressed as three fusion proteins in Escherichia coli. O-GlcNA-case activity showed in the order of thioredoxin fusion> $6{\times}His$ tag> GST fusion. O-GlcNAcase had enzy-matic activity against only ${\rho}$NP-GlcNAc of seven tested substrate analogs. Blast search revealed that O-GlcNAcase has two conserved domains, amino terminal hyaluronidase-like domain and carboxy terminal N-acetyltransferase domain. Extensive deletion studies were done to define catalytically important domains. The deletions of hyaluronidase-like domain and N-acetyltransferase domain abolished enzyme activity. But, N-ter-minal 55 amino acid deletion and C-terminal truncation showed lower activity. Based on deletion analysis, we suggest that hyaluronidase-like domain is essential for enzyme activity and carboxy terminal N-acetyltrans-ferase domain may be modulatory function.

Structural Studies on PDE and Inhibitor Complexes

  • Lee, Jie-Oh
    • Proceedings of the Korean Biophysical Society Conference
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    • 2002.06b
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    • pp.15-15
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    • 2002
  • Cyclic nucleotide phosphodiesterases (PDEs) regulate physiological processes by degrading ubiquitous intracellular second messengers, cAMP or cGMP. The first crystal structure of PDE4D catalytic domain and a bound inhibitor, zardaverine, was determined. Zardaverine binds to a highly conserved pocket that includes the catalytic metal binding site.(omitted)

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Analyses of Elementary School Students' Scientific Creativity in Cognitive Domain by Applying a Brain-Based Evolutionary Approach to Science Instruction (인지적 영역 중심의 뇌기반 진화적 접근법을 적용한 초등 과학 수업에서 학생들의 과학 창의성 분석)

  • Ok, Chanmi;Lim, Chae-Seong;Kim, Sung-Ha;Hong, Juneuy
    • Journal of Korean Elementary Science Education
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    • v.35 no.4
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    • pp.469-478
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    • 2016
  • A brain-based evolutionary approach developed by reflecting the brain functions and authentic science is consisted of Affective, Behavioral, and Cognitive domains, and within each domain the processes of Diversifying, Evaluating, and Furthering are proceeded (ABC-DEF). Two core components of creativity of originality and usefulness are inherent in each step. So, this study analyzed scientific creativity with the originality and usefulness components in cognitive domain, which is composed of diversifying the meanings inherent in the results of observations or experiments (C-D), evaluating the meanings (C-E), and furthering (C-F) in learning of 'World of Plants' unit which includes two topics of 'Plants on Land' and 'Plants in Water and Special Environment'. A total of 20 fourth grade students at Y elementary school in Gyeonggi province participated in the study. The main results of this study are as follows. First, the scientific creativity in step C-D (Diversifying stage) was assessed according to the scientific creativity assessment formula. The scores of scientific creativity were quite different with topics and showed different pattern in the originality and usefulness components. Second, when the students compare and evaluate the values of each meaning (C-E stage), they weighed more on usefulness than originality, such as "because it is useful" or "because it solve many everyday problems". Third, the overall scores of scientific creativity in step C-F (Furthering stage), as compared with those of step C-D, were low and showed decrease in the average scores of originality from 9.8 to 7.5 points, whereas increase in the average scores of usefulness from 5.4 to 6.1 points. In conclusion, these results showed that, even though the levels were not so high, the students, as scientists, can exhibit the scientific creativity in the processes of diversifying, comparing and evaluating, and applying the meanings about the results obtained by observations or experiments. The specific and various strategies to help students express their potential scientific creativity more effectively need to be developed.

INEQUALITIES FOR THE INTEGRAL MEANS OF HOLOMORPHIC FUNCTIONS IN THE STRONGLY PSEUDOCONVEX DOMAIN

  • CHO, HONG-RAE;LEE, JIN-KEE
    • Communications of the Korean Mathematical Society
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    • v.20 no.2
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    • pp.339-350
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    • 2005
  • We obtain the following two inequalities on a strongly pseudoconvex domain $\Omega\;in\;\mathbb{C}^n\;:\;for\;f\;{\in}\;O(\Omega)$ $$\int_{0}^{{\delta}0}t^{a{\mid}a{\mid}+b}M_p^a(t, D^{a}f)dt\lesssim\int_{0}^{{\delta}0}t^{b}M_p^a(t,\;f)dt\;\int_{O}^{{\delta}O}t_{b}M_p^a(t,\;f)dt\lesssim\sum_{j=0}^{m}\int_{O}^{{\delta}O}t^{am+b}M_{p}^{a}\(t,\;\aleph^{i}f\)dt$$. In [9], Shi proved these results for the unit ball in $\mathbb{C}^n$. These are generalizations of some classical results of Hardy and Littlewood.