• International Journal of Oral Biology
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• 제45권2호
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• pp.51-57
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• 2020

Thromboelastography or rotational thromboelastometry, is being increasingly utilized in cardiac surgery of late. However, it is an indirect test and is not available in all centers. Low fibrinogen levels before and after cardiopulmonary bypass (CPB) have been described to be associated with postoperative bleeding in cardiac surgery. This study explored the usefulness of reduction ratio of the fibrinogen levels before CPB (preCPB) and after CPB (postCPB) in predicting postoperative hemorrhage. A retrospective, observational study of adult patients who underwent cardiac surgery with CPB between February 2014 and January 2016 was conducted, which included a total of 264 patients. The fibrinogen levels were measured twice, preCPB and postCPB, and the fibrinogen reduction ratio was acquired [(preCPB - postCPB)/preCPB]. Postoperative blood loss, which was defined as the blood collected from the chest drain for 12 hours following arrival at the intensive care unit, was considered severe if it was more than 1,000 mL. A multivariate analysis showed that fibrinogen reduction ratio, sex, and postCPB platelet count were significantly associated with severe postoperative bleeding. However, the pre- and postCPB fibrinogen levels were not significantly associated with severe bleeding. Furthermore, a fibrinogen reduction ratio of > 41.3% was independently associated with postoperative severe bleeding, with an odds ratio of 3.472 (1.483-8.162). These results suggest that the reduction ratio of pre- and postCPB fibrinogen levels may be utilized in predicting postoperative bleeding.

• International Journal of Aeronautical and Space Sciences
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• 제15권1호
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• pp.97-101
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• 2014

With the increase in global air travel, aircraft noise has become a major public issue. In modern aircraft engines, only a small proportion of the air that passes through the whole engine actually goes through the core of the engine, the rest passes around it down the bypass duct. A successful method of reducing noise further, even in ultra-high bypass ratio engines, is to absorb the sound created within the engine. Acoustically absorbent material or acoustic liners have desirable acoustic attenuation properties and thus are commonly used to reduce noise in jet engines. The liners typically are placed upstream and downstream of the rotors (fans) to absorb sound before it propagates out of the inlet and exhaust ducts. Noise attenuation can be dramatically improved by increasing the area over which a noise reducing material is applied and by placing the material closer to the noise source. In this paper we will briefly discuss acoustic liner applications in modern turbofan engines.

• 태양에너지
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• 제17권2호
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• pp.3-11
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• 1997

열펌프건조기는 증발기에 의한 냉각및 감습기능과 응축기에 의한 가열기능을 대류형건조기와 연계시킴으로써 필연적 손실로 분류되던 배기가 갖고 있는 현열과 잠열을 회수하여 재활용할 수 있는 이점이 있다. 본 연구에서는 HFC134a를 냉매로 사용한 배치형(batch type) 열펌프건조기를 설계제작하여 건조실의 유지온도, 공기의 바이패스비(bypass ratio), 냉매의 과열도를 일정하게 유지하고 정면풍속(face velocity)과 압축기속도를 변화시켜 건조기의 성능을 분석하였으며 정면풍속의 증가에 따라 열펌프의 성적계수는 증가하나 SMER(Specific Moisture Extraction Rate)은 감소하였다.

• Geomechanics and Engineering
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• 제28권2호
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• pp.135-143
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• 2022

Soils are natural granular materials whose mechanical properties differ according to the size and composition of the particles, so soils exhibit an obvious scale effect. Traditional soil mechanics is based on continuum mechanics, which can not reflect the impact of particle size on soil mechanics. On that basis, a matrix-reinforcing-particle cell model is established in which the reinforcing particles are larger-diameter sand particles and the matrix comprises smaller-diameter bentonite particles. Since these two types of particles deform differently under shear stress, a new shear-strength theory under direct shear that considers the stress concentration and bypass phenomena of the matrix is established. In order to verify the rationality of this theory, a series of direct shear tests with different reinforcing particle diameter and volume fraction ratio are carried out. Theoretical analysis and experimental results showed that the interaction among particles of differing size and composition is the basic reason for the size effect of soils. Furthermore, the stress concentration and bypass phenomena of the matrix enhance the shear strength of a soil, and the volume ratio of reinforcing particles has an obvious impact on the shear strength. In addition, the newly proposed shear-strength theory agrees well with experimental values.

• Journal of electromagnetic engineering and science
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• 제14권4호
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• pp.393-398
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• 2014

A highly efficient dual-mode linear CMOS stacked-FET power amplifier (PA) is implemented for 3G UMTS and 4G LTE handset applications. High efficiency is achieved at a backed-off output power ($P_{out}$) below 12 dBm by employing an active-bypass amplifier, which consumes very low quiescent current and has high load-impedance. The output paths between high- and low-power modes of the PA are effectively isolated by using a bypass switch, thus no RF performance degradation occurs at high-power mode operation. The fabricated 900 MHz CMOS PA using a silicon-on-insulator (SOI) CMOS process operates with an idle current of 5.5 mA and shows power-added efficiency (PAE) of 20.5%/43.5% at $P_{out}$ = 12.4 / 28.2 dBm while maintaining an adjacent channel leakage ratio (ACLR) better than -39 dBc, using the 3GPP uplink W-CDMA signal. The PA also exhibits PAE of 35.1% and $ACLR_{E-UTRA}$ of -33 dBc at $P_{out}$ = 26.5 dBm, using the 20 MHz bandwidth 16-QAM LTE signal.

• Journal of Obesity & Metabolic Syndrome
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• 제27권4호
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• pp.248-253
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• 2018

Background: Sirtuins mediate metabolic responses to nutrient availability and slow aging and accompanying decline in health. This study was designed to assess the expressions of sirtuin1 (SIRT1) and sirtuin3 (SIRT3) in the liver and hypothalamus after duodenal-jejunal bypass (DJB) surgery in rats. Methods: A total of 38 rats were randomly assigned to either sham group (n=8) or DJB group (n=30). DJB group was again divided into three groups according to the elapsed time after surgery (10 weeks, DJB10; 16 week, DJB16; 28 week, DJB28). The mRNA and protein expressions of SIRT1 and SIRT3 in the liver and hypothalamus were measured by reverse transcription polymerase chain reaction, Western blot, and immunohistochemistry analyses. $NAD^+/NADH$ ratio was also measured. Results: We found increased mRNA and protein expression levels of SIRT1 in the liver of DJB16 and DJB28 groups compared with those of sham group. The mRNA and protein expressions of SIRT3 in the liver of DJB group increased proportionally to the elapsed time after DJB surgery. The mRNA expression levels of SIRT1 in the hypothalamus increased in DJB16 and DJB28 groups and protein expression levels of SIRT1 in the hypothalamus increased in DJB10, DBJ16, and DJB28 groups compared with sham group. We observed that mRNA and protein levels of SIRT3 in the hypothalamus of DJB group were not changed. Conclusion: This study proves that DJB increases SIRT1 and SIRT3 expressions in the liver and SIRT1 expression in the hypothalamus. These results suggest the possibility of sirtuins being involved in bypass surgery-induced metabolic changes.

• 한국연소학회:학술대회논문집
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• 한국연소학회 제26회 KOSCO SYMPOSIUM 논문집
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• pp.111-117
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• 2003

The present study discusses about the combustion and thermal flow characteristics of a G+R type incinerator, which is under construction for MAPO Incineration system, to evaluate the effects of various operating and design parameters. A bed combustion model is developed to simulate the waste bed combustion on the stoker. The effects of waste composition and primary air distribution are estimated. The results of the waste bed combustion model is applied to CFD(computational fluid dynamics) simulation, which simulates the detail of the thermal flow in the combustion chamber. The effects of bypass damper opening ratio, primary air distribution, and secondary air jet configuration are discussed.

• 대한핵의학회지
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• 제31권1호
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• pp.36-42
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• 1997

관동맥우회로술을 실시하고 심근 SPECT를 수술전과 수술 후 3개월에 실시한 44명의 환자(남:여=25:19, 나이 $57.1세{\pm}8.2$)를 대상으로 악화된 심근 관류를 분절과 관상동맥영역의 수준에서 분석하였을 때 분절의 수준에서는 LCx영역에 있는 분절들이 유의하게 악화되었으나[odds ratio=2.54 (95% 신뢰구간. 1.53-4.22, p<0.01)] 영역의 수준에서는 LCx가 관류악화의 위험 인자는 아니었다. 혈관이식편의 종류와 관상동맥성형술 여부도 심근 관류 악화에 영향을 끼치지 못했다. 결과로 aortic cross clamp time이나 심폐우회시간, 원래 mid-LAD의 직경 등 알려진 수술전후 심근경색의 위험 인자들에 대한 데이터를 종합하여 심근 SPECT의 관류 악화를 평가하여야 하며 이 연구는 수술전후 심근경색을 연구하는 기본적인 데이터로 쓰일 수 있다고 생각하였다.

• 대한임상검사과학회지
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• 제36권2호
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• pp.153-157
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• 2004

The aim of our study is to determine maximum surgical blood order schedule (MSBOS) in each surgical operation through analyzing usage of blood products at Bundang Jesaeng General Hospital. We investigated the amount of transfused red cells for each operation and calculated crossmatching-to-transfusion ratio (C/T ratio) and MSBOS. This was accomplished by referring to the Laboratory Information System program during 1 year from January through December 2003. Coronary artery bypass surgery and decompressive craniectomy showed the highest MSBOS in our hospital. The average C/T ratio was 3.2 and excessive reservations for blood products have been made for many operations. From this study, guidelines for the optimal blood ordering for each surgery were suggested.

• Journal of Chest Surgery
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• 제31권5호
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• pp.494-501
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• 1998

저자들은 1993년 5월부터 1995년 5월까지 인공심폐기를 사용한 개심술을 받은 211명을 대상으로 후향적 조사를 하였다. 우리는 술후 새로이 발생한 급성 신부전에 초점을 두었기에 술전 creatinine 수치가 1.5 mg/dL이하였던 환자를 다변수 통계를 이용하여 조사하였다. 술전 신기능이 정상이었던 환자는 198명(74%)이었는데 이중 27명(14%)이 술후 신장 합병증을 보였다. 20명(10%)은 신기능 이상상태(1.5$\leq$serum creatinine level < 2.5 mg/dL)였고, 7명(4%)은 급성 신부전(serum creatinine level$\geq$2.5mg/dL) 상태였다. 수술 사망률은 정상에서는 5.8%, 신기능 이상 환자에서는 5%, 급성 신부전 환자에서는 43%였다(p=0.036). 술후 급성 신부전은 심혈관 합병증, 호흡기 합병증과 함께 수술 사망의 독립적인 위험인자로 밝혀졌고, 다변수 분석에서 술후 급성 신부전 발생 위험인자는 고령, 응급수술, 저심박출증 등이었다. 술전 신부전을 보였던 13명에서 정상이었던 환자보다 술후 유병률과 사망률이 높았다. 결론적으로 술전 신기능 이상을 보이지 않았던 환자에서 술후 급성 신부전의 발생률은 낮았으나, 신부전과 동반된 사망률은 여전히 높았다. 그러므로 술전, 술중, 술후 신부전 발생에 영향을 주는 혈류역학 인자들의 세심한 관찰이 요구된다.