• Journal of Pharmaceutical Investigation
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• v.35 no.4
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• pp.255-263
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• 2005

Research was undertaken to compare the pharmacological activity of Lithospermi radix (LR) reported as an oriental medicine for classical uses. LR contains naphthoquinone pigments : shikonin, acetylshikonin, isobutylshikonin, etc. LR is used for the treatment of excision wound, burn, eczema, blister, scarlatina and septicemia as antifebrile, antidotic and antiphlogistic. Gardeniae fructus (GF) has been used for the treatment to jaundice, hepatic disease, anti-inflammatory and analgesic effects, and it contains crocin, geniposide and its derivatives. The therapeutic effects of burn and excision wound healing from LR & GF hydrogel with $Nano-ATP^{\circledR}$ (GLN) were investigated. To evaluate the therapeutic value of various hydrogels, thermal burn model and excision wound mouse model were used. The burn and wound reduction rate and therapeutic period were measured to calculate the healing extent after 5 experiments. The 2nd degree burn was prepared on hairless mouse back skin and dressing with collagen. The burn and wound reduction rate of GLN hydrogel treated group decreased more rapidly than that of other gel group in animal model. Furthermore therapeutic periods of GLN hydrogel treated group was shorter than that of other gel group. In anti-inflammatory test, GLN hydrogel treated group decreased edema rapidly than that of other gel group. These results suggest that the GLN hydrogel treatment has an therapeutic effect on burn and excision wound healing.

• Journal of Veterinary Science
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• v.22 no.1
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• pp.9.1-9.11
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• 2021

Background: Scalding burn injuries can occur in everyday life but occur more frequently in young children. Therefore, it is important to develop more effective burn treatments. Objectives: This study examined the effects of bee venom (BV) stimulation on scalding burn injury-induced nociception in mice as a new treatment for burn pain. Methods: To develop a burn injury model, the right hind paw was immersed temporarily in hot water (65℃, 3 seconds). Immediately after the burn, BV (0.01, 0.02, or 0.1 mg/kg) was injected subcutaneously into the ipsilateral knee area once daily for 14 days. A von Frey test was performed to assess the nociceptive response, and the altered walking parameters were evaluated using an automated gait analysis system. In addition, the peripheral and central expression changes in substance P (Sub P) were measured in the dorsal root ganglion and spinal cord by immunofluorescence. Results: Repeated BV treatment at the 2 higher doses used in this study (0.02 and 0.1 mg/kg) alleviated the pain responses remarkably and recovered the gait performances to the level of acetaminophen (200 mg/kg, intraperitoneal, once daily), which used as the positive control group. Moreover, BV stimulation had an inhibitory effect on the increased expression of Sub P in the peripheral and central nervous systems by a burn injury. Conclusions: These results suggest that a peripheral BV treatment may have positive potency in treating burn-induced pain.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.4
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• pp.774-781
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• 2002

This study was carried out to test the recuperative effect of 2 types of sample drugs for 3 degree burn. The burn injury was made by iron plate heated in the boiling water. The Sprague Dawley rats were shaven with a razor preliminarily and burned by direct contact method for 10 seconds. The experimental groups were classified with 5 each-normal, control, MEBO ointment, sample A, sample B. The effect of the sample drugs were decided by histological results after 3 week application. The results were as following. The 3 treatment groups recovered the burn injury faster than control group. The recuperative effect precedes about 4-5 days at the time of 15th day and 1 week at the time of 3rd week. The therapeutical procedure of 3 treatment groups was similar with naked eye and with microscopic histology in the 1 st, 2nd and 3rd specimens. So there weren't significant differences in curative effect in 3 treatment groups of this experiment. But a regeneration of hair follicle was noted in Sample B uniquely. These results suggested that 3 burn remedies have similar effect of therpy, but sample B containing yolk sac oil has slightly better effect in part of hair regeneration.

• Transactions of the Korean Society of Automotive Engineers
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• v.4 no.4
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• pp.80-86
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• 1996

In order to decrease fuel comsumption rate and emissions, lean burn engine which has equipped swirl control valve, is investigated experimentally on the test bench. Single cylinder engine was used to test the combustion and emission performance with 4 kinds of swirl valve. Decrease in the carbon monoxide, hyerocarbon and specific fuel consumption was shown at the lean condition, which means that a good choice of swirl valve on the given intake port geometry can be used to increase the combustion efficiency and lean limit.

• Journal of the Korean Society for Railway
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• v.15 no.6
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• pp.566-571
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• 2012

The door systems in urban railway vehicles, through heavy maintenance checks by six years, 75 parts for 34 part types in 75 units have to be replaced periodically, and the remaining 68 parts for 40 part types to be replaced occasionally based on the necessity. Even though this process makes the door systems almost to be initial status, the systems have complicated mixes of components with new parts and used and then have different property from the original ones. This study suggested a burn-in test as a subsidiary tool to improve the reliability of urban railway vehicles, and suitable for testing conditions and the proposed new target value.

• Journal of muscle and joint health
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• v.23 no.1
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• pp.28-38
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• 2016

Purpose: The purpose of this study was to investigate post-burn itching relevant characteristics in the rehabilitation phase. Methods: Ninety four burn patients who were hospitalized in the rehabilitation phase participated in the study. Self-reported Leuven itch scale-Korean was used to evaluate itching related characteristics. Data were analyzed with descriptive analysis, $x^2$ test, and Kruskal-Wallis test. Results: All subjects except two had the itching. Itching frequency revealed that 68.1% of subjects experienced itching one or more episodes a day or always, and 18.7% had episode durations lasting more than 2 hours per incidence. Mean severity and distress of itching was $5.3{\pm}2.4$ and $5.2{\pm}2.5$, respectively. Itching sensation dimension of tickling was 56.4%. More than 25% of subjects "often" or "always" affected reduced quality of life, loss of concentration, bad mood, and difficulty in falling asleep. Satisfaction with itching treatment was intermediate level. Conclusion: Post-burn itching in the rehabilitation phase was a significant problem despite pruritus treatment. Based on the finding of this study, development of comprehensive and tailored nursing intervention programs for itching could be suggested.

• Journal of Hospice and Palliative Care
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• v.13 no.3
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• pp.161-168
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• 2010

Purpose: This study investigated the Korean social workers’ burn-out factors and personal traits in hospice and palliative care field, and also examined the effect and correlation between their professionality, social support and supervision. Methods: Data (N=46) from 46 social workers working at hospice and palliative care field were collected, and the data were analyzed for the inferential statistics using t-test, ANOVA, correlation and multiple regression with the SPSS 12.0 program. Results: General factors of the burn-out were age and work experience. The effect of the organization environment is greatly dependant on social support and supervision, and the burn-out were protected when workers got an emotional support from their family. For the workers with supervision, the less negative feeling, the better for the burn-out protection. Furthermore, the low burn-out was thought about when professional organization, self regulation, job vocation and autonomy were utilized. Regression analysis needed that the burn-out were protected well when individual autonomy among expertise was guaranteed. As for social support, vertical support was able to protect physical burn-out. Conclusion: The training program for social workers in hospices and palliative care field is essential to reduce and prevent the burn-out. Hospice should be more activated and a training program with up-to-date knowledge and information should be adopted.

• Journal of Mechanical Science and Technology
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• v.14 no.10
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• pp.1151-1158
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• 2000

Combustion analysis based on cylinder-pressure provides a mechanism through which a combustion researcher can understand the combustion process. The objective of this paper was to identify the most significant sources of cycle-to-cycle combustion variability in a spark ignition engine at idle. To analyse the cyclic variation in a test engine, the burn parameters are determined on a cycle-to-cycle basis through the analysis of the engine pressure data. The burn rate analysis program was used here and the burn parameters were used to determine the variations in the input parameter-i. e., fuel, air, and residual mass. In this study, we investigated the relationship of indicated mean effective pressure (IMEP), coefficient of variation (COV) of IMEP, burn angles, and lowest normalized value (LNV) in a spark ignition engine in a view of cyclic variations.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2003.06a
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• pp.1249-1252
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• 2003

To analyse the cyclic variations in a test engine, the burn parameters are determined on a cycle-to-cycle basis through the analysis of the engine pressure data. Combustion analysis based on cylinder-pressure provides a mechanism through which a combustion researcher can understand the combustion process. The objective of this paper is to identify the most significant sources of cycle-to-cycle combustion variability in a spark ignition engine at idle. The burn rate analysis program was used and the burn parameters were used to determine the variations in the input parameter. In this study, the author investigated the relationship of indicated mean effective pressure, coefficient of variation of indicated mean effective pressure and burn angles, and lowest normalized value in a spark ignition engine for the cyclic variations.

• Journal of Trauma and Injury
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• v.28 no.3
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• pp.170-176
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• 2015

Purpose: The aims of this study were to discuss treatment and prevention under the age of 18 to identify the characteristics of the electrical burn patients. Methods: We retrospectively reviewed medical records of 97 patients with under age 18 of electric burn who were treated in emergency department of quarterly over 10,000 targets within the desired hospital for evaluation of electrical injuries between January 1, 2009 and December, 2013. We investigated age, gender, injury mechanism, season, degree of burn, surface of burn, complication, blood test, and voltage, kind of current. Results: Of the patients, 50 (50.5%) patients were in the first degree burn and 47 (49.5%) patients were in second degree burn. 68 (70.1%) patients had electric burn at home. 75 (85.2%) of 88 patients had normal sinus rhythm and other 13 people showed a RBBB, VPC, sinus bradycardia, sinus tachycardia. 41 (42.3) of 97 patients were in infants and 26 (26.8%) patients were in adolescence. Conclusion: The results of this study emphasize the need for prevention of electricity at home for childhood and education of the adolescence.