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Novel nomogram-based integrated gonadotropin therapy individualization in in vitro fertilization/intracytoplasmic sperm injection: A modeling approach

  • Ebid, Abdel Hameed IM;Motaleb, Sara M Abdel;Mostafa, Mahmoud I;Soliman, Mahmoud MA
    • Clinical and Experimental Reproductive Medicine
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    • v.48 no.2
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    • pp.163-173
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    • 2021
  • Objective: This study aimed to characterize a validated model for predicting oocyte retrieval in controlled ovarian stimulation (COS) and to construct model-based nomograms for assistance in clinical decision-making regarding the gonadotropin protocol and dose. Methods: This observational, retrospective, cohort study included 636 women with primary unexplained infertility and a normal menstrual cycle who were attempting assisted reproductive therapy for the first time. The enrolled women were split into an index group (n=497) for model building and a validation group (n=139). The primary outcome was absolute oocyte count. The dose-response relationship was tested using modified Poisson, negative binomial, hybrid Poisson-Emax, and linear models. The validation group was similarly analyzed, and its results were compared to that of the index group. Results: The Poisson model with the log-link function demonstrated superior predictive performance and precision (Akaike information criterion, 2,704; λ=8.27; relative standard error (λ)=2.02%). The covariate analysis included women's age (p<0.001), antral follicle count (p<0.001), basal follicle-stimulating hormone level (p<0.001), gonadotropin dose (p=0.042), and protocol type (p=0.002 and p<0.001 for short and antagonist protocols, respectively). The estimates from 500 bootstrap samples were close to those of the original model. The validation group showed model assessment metrics comparable to the index model. Based on the fitted model, a static nomogram was built to improve visualization. In addition, a dynamic electronic tool was created for convenience of use. Conclusion: Based on our validated model, nomograms were constructed to help clinicians individualize the stimulation protocol and gonadotropin doses in COS cycles.

Building Method an Image Dataset for Tracking Objects in a Video (동영상 내 객체 추적을 위한 영상 데이터셋 구축 방법)

  • Kim, Ji-Seong;Heo, Gyeongyong;Jang, Si-Woong
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.25 no.12
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    • pp.1790-1796
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    • 2021
  • A large amount of image data sets are required for image deep learning, and there are many differences in the method of obtaining images and constructing image data sets depending on the type of object. In this paper, we presented a method of constructing an image data set for deep learning and analyzed the performance that varies depending on the object to be tracked. We took a video by rotating the object, and then created a data set by segmenting the video using the proposed data set construction method. As a result of performance analysis, detection rate was more than 95%, and detection rate of objects with little change in shape was higher performance. It is considered that it is effective to use the data set construction method presented in this paper for a situation in which it is difficult to obtain image data and to track an object with little change in shape within a video.

Seismic performance of CFS shear wall systems filled with polystyrene lightweight concrete: Experimental investigation and design methodology

  • Mohammad Rezaeian Pakizeh;Hossein Parastesh;Iman Hajirasouliha;Farhang Farahbod
    • Steel and Composite Structures
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    • v.46 no.4
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    • pp.497-512
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    • 2023
  • Using light weight concrete as infill material in conventional cold-formed steel (CFS) shear wall systems can considerably increase their load bearing capacity, ductility, integrity and fire resistance. The compressive strength of the filler concrete is a key factor affecting the structural behaviour of the composite wall systems, and therefore, achieving maximum compressive strength in lightweight concrete while maintaining its lightweight properties is of significant importance. In this study a new type of optimum polystyrene lightweight concrete (OPLC) with high compressive strength is developed for infill material in composite CFS shear wall systems. To study the seismic behaviour of the OPLC-filled CFS shear wall systems, two full scale wall specimens are tested under cyclic loading condition. The effects of OPLC on load-bearing capacity, failure mode, ductility, energy dissipation capacity, and stiffness degradation of the walls are investigated. It is shown that the use of OPLC as infill in CFS shear walls can considerably improve their seismic performance by: (i) preventing the premature buckling of the stud members, and (ii) changing the dominant failure mode from brittle to ductile thanks to the bond-slip behaviour between OPLC and CFS studs. It is also shown that the design equations proposed by EC8 and ACI 318-14 standards overestimate the shear force capacity of OPLC-filled CFS shear wall systems by up to 80%. This shows it is necessary to propose methods with higher efficiency to predict the capacity of these systems for practical applications.

Research on Paper Board Banja With Woomul(井) Structure of Royal Palaces in the Joseon Dynasty (조선시대 궁궐건축의 우물천장 구조 종이반자 연구)

  • Lee, Jong-Seo
    • Journal of architectural history
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    • v.32 no.1
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    • pp.61-72
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    • 2023
  • Korean architecture classifies Banja (the decorated flat of the ceiling visible from the inside) of Royal Palaces into two types: Woomul(water-well, 井) banja, which inserts rectangular wooden board into lattice frame, and paper banja, which applies paper to the flat ceiling. Such classification was established in the 19th century. Before that, Banja was classified according to what was inserted into the lattice frame, either wooden or paper board. At first, the banja that used paper board was widely installed regardless of the purpose or nobility of the building. However, since the 17th century, the use of paper board banja became mostly restricted to Ondol (Korean floor heating system) rooms which are characterized by private usage and the importance of heating, and it was considered inferior to wooden board banja in terms of rank or grace. The contemporary paper banja was mainly installed in low-rank ondol rooms until the late 19th century to early 20th century, when roll-type wallpaper was introduced from the West and the paper banja came to decorate the King's and Queen's bedrooms. The traditional paper board banja benefits heat reservation, reduces the weight of the ceiling, and allows the adjustment of the lattice frame size. Furthermore, it can feature unique artistry if covered with blue, white, or red Neung-hwa-ji (traditional flower pattered paper).

Exploration of Teacher Pedagogical Content Knowledge (PCK) and Teacher Educator PCK Characteristics in Future School Science Education

  • Youngsun Kwak;Kyu-dohng Cho
    • Journal of the Korean earth science society
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    • v.44 no.4
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    • pp.331-341
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    • 2023
  • The goal of this study was to examine the PCK required for science teachers and PCK required for university teacher educators in terms of school science knowledge, science teaching and learning, and the role of science educators, which are the main axes of science education in future schools, and to explore the relationship between them. This study is a follow-up to a previous stage of research that explored the prospects for changes in schools in the future (2040-2050) in terms of school knowledge, educational methods, and teacher roles. Based on in-depth interviews, qualitative and semantic network analyses were conducted to derive and compare the characteristics of PCK and PCK. As for the main research results, science teacher PCK in future schools should include expertise in organizing science classes centered on convergence topics, expertise in digital platforms and ICT use, and expertise in building a network of learning communities and resources, as part of the expertise of human teachers differentiated from AI. Teacher educators' PCK includes expertise in the research and development of T-L methods using AI, expertise in the knowledge construction process and practice, and expertise in developing preservice teachers' research competencies. Discussed in the conclusion is the change in teacher PCK and teacher educator PCK with changes in science knowledge, such as convergence-type knowledge and cognition-value integrated knowledge; and the need to emphasize values, attitudes, and ethical judgments for the coexistence of humans and non-humans as school science knowledge in the post-humanism future society.

Cutting-Line Sensing Methods for an Automated Concrete Pile Cutter (파일 두부정리 자동화 장비를 위한 두부정리선 센싱 방법)

  • Kim, Sung-Keun;Kim, Young-Suk;Lee, Junbok
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.6D
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    • pp.985-993
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    • 2006
  • The use of prefabricated concrete piles have been gradually increased in many construction sites. One of main works for building a concrete pile foundation is to crush a part of pile head which is compressed with more than $800kg/cm^2$. A pile cutting work is usually performed by a crusher and three to four skilled workers. Recent reports on the pile cutting work reveal that a lot of cracks which significantly reduce the strength of the pile and are frequently made during pile cutting operations and it is very repetitive and labor intensive work. To improve productivity, safety, and quality of the conventional concrete pile cutting work, the research on developing an automated concrete pile cutter has been performed. In this paper, sensing methods for detecting a pile cutting line are suggested with operation process algorithms. The suggested methods are very important to develop the automated pile cutter. A pilot-type of the automated pile cutter that adopt one of the suggested sensing methods, is developed and tested in a construction site.

Numerical investigation on seismic behaviors of midrise special moment resistant frame retrofitted by timber-base bracings

  • Ainullah-Mirzazadah, Ainullah-Mirzazadah;Sabbagh-Yazdi, Saeed-Reza
    • Steel and Composite Structures
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    • v.45 no.1
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    • pp.83-100
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    • 2022
  • Timber is one of the few natural, renewable building materials and glulam is a type of engineering wood product. In the present work, timber-based braces are applied for retrofitting midrise Special Moment Resisting Frame (SMRF) using two types of timber base braces (Timber base glulam, and hybrid Timber-Steel-BRB) as alternatives for retrofitting by traditional steel bracings. The improving effects of adding the bracings to the SMRF on seismic characteristics of the frame are evaluated using load-bearing capacity, energy dissipation, and story drifts of the frame. For evaluating the retrofitting effects on the seismic performance of SMRF, a five-story SMRF is considered unretofitted and retrofitted with steel-hollow structural section (HSS) brace, Glued Laminated Timber (Glulam) brace, and hybrid Timber-Steel BRB. Using OpenSees structural analyzer, the performance are investigated under pushover, cyclic, and incremental loading. Results showed that steel-HSS, timber base Glulam, and hybrid timber-steel BRB braces have more significant roles in energy dissipation, increasing stiffness, changing capacity curves, reducing inter-story drifts, and reducing the weight of the frames, compared by steel bracing. Results showed that Hybrid BRB counteract the negative post-yield stiffness, so their use is more beneficial on buildings where P-Delta effects are more critical. It is found that the repair costs of the buildings with hybrid BRB will be less due to lower residual drifts. As a result, timber steel-BRB has the best energy dissipation and seismic performance due to symmetrical and stable hysteresis curves of buckling restrained braces that can experience the same capacities in tension and compression.

Marketing Feng Shui to Asia: A Case Study

  • Bela Florenthal;Noriko Yagi;Hongjiang Xu
    • Asia Marketing Journal
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    • v.11 no.2
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    • pp.1-20
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    • 2009
  • Feng Shui practice is very popular in East Asia and has been rapidly adopted by the population of the West. As Feng Shui involves knowledge of object placement, it opens opportunities to market Feng Shui knowledge and products. This paper presents an analysis of a successful Feng Shui enterprise, World of Feng Shui (WOFS), that has been established by a well-known Feng Shui expert Lillian Too and her daughter Jennifer Too. The enterprise's marketing strategies and tactics are tied to the theoretical concept of social influence, widely researched in the consumer behavior literature. The three types of social influence (informational, utilitarian, and value-expressive) are examined in relation to WOFS' marketing strategies using secondary data material. The main results indicate that the strategies of WOFS enterprise address all three types of social influence. The articles generated on-and off-line can be mostly associated with the informational influence. The off- line activities such as events, courses/workshops, and TV shows are also informational in nature. The Q & A sections/postings can be considered as representative of the utilitarian influence. They give experts (e.g., Lillian Too) the opportunity to provide individuals with problem-specific recommendations. Mega-mall website provides the value-expressive influence as purchase and consumption of the Feng Shui products is most susceptible to this type of influence. In terms of implications, WOFS enterprise strategies are suitable not only for consumes but also for business executives in Asia and in the West as architects, designers, and homeowners across continents use Feng Shui practices for building placements and decoration of dwellings and workplaces. Feng Shui practice has some limitations such as conflicting opinions of experts and increased complexity when the dimension of time is taken into consideration. Still, Feng Shui as a practice is growing globally adjusting itself to regional and cultural challenges.

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Derivation of Linkage Strategies for Domestic Order Documents and Standards for BIM Application Projects - Proposing BIM Design Procurement Use Guides for Domestic Railway Field by Analyzing Singapore Requirements Documents - (BIM 적용사업 대상의 국내 발주문서 및 기준 간 연계전략 도출 - 싱가폴 요구사항 지시서 분석을 통한 국내 철도분야 BIM 전면설계 발주문서 활용방법 제안 -)

  • Chong, HeeGun;Kim, Do-Young;Hong, Chang Hee;Lee, Jaewook;Moon, Hyeonsuk
    • Journal of KIBIM
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    • v.13 no.4
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    • pp.26-35
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    • 2023
  • Recently, mandatory BIM design has been enforced in the civil engineering field, focusing on public projects, and inducement measures to actively participate in BIM by participating subjects are required. The BIM ordering documents must reflect the characteristics of the BIM project, current construction standards and laws, and environmental conditions of domestic participants. In this study, we analyze the ordering documents used in domestic and overseas civil engineering BIM projects to determine whether they meet the purpose of BIM. In the future, items that consider the existing heterogeneous data linkage and compatibility, the connectivity with the current construction guidelines and laws, the cost of the designer and the input personnel are prepared for the part that does not meet the BIM purpose. Furthermore, the written order documents are verified through interviews with experts who have experience in BIM projects. Through the results of this study, I would like to propose a consultation system strategy to prepare and present items according to the purpose and type of project by client.

Characteristics and Policy Implications of Private Development Parks in Japan (일본 민설공원 제도의 특성과 시사점)

  • Kim, Hyun
    • Journal of the Korean Institute of Landscape Architecture
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    • v.44 no.1
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    • pp.119-128
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    • 2016
  • Urban park planning has become difficult due to the lack of municipal funds. Thereupon, a special scheme was imposed for city park planning. Since then, a legal amendment was made for economical improvement and more active participation. However, there are a lot of questions about whether it was a suitable direction for parks and where it should be emphasized for public interest. Base on these concerns, this study examined the basis and characteristics of location, creation, and maintenance of private development parks in Japan, which was the policy model of Korean private parks. Location and space planning of private development parks was made up considering an effective green network and disaster prevention function, and a minimum area was about 1.42ha. The minimum area, 1ha, was established on the basis of considering realistic possibilities, disaster protection, and universal validity. It was also amended to consider the standard of type two mid- to high-rise exclusive residential areas and consultation with regional governance. Finally, it was built on the lowest limit of ordinance of the relevant city; for example, 100% of the floor area ratio, 30% of the building coverage ratio, and the maximum height of 11 stories, etc. For maintenance, private and public sectors were working together. Maintenance fees for 35 years (based on $300yen/m^2$ per month) were paid en bloc by the licensee. However, the city was paid for facilities that accompanied excessive maintenance costs. Meanwhile, it seemed difficult to introduce attractive profit facilities because of the limitations in location, usage permission, and introduction equipment; furthermore, there were problems with management authority, and the burden of expenses was deducted. For creating private Korean parks, this study suggested that we should build priority of creating city parks and select appropriate locations first; also, we need to make criteria for location, creation, and standard management rules that are relevant to the whole nation of Korea.