• 대한기계학회논문집B
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• 제29권5호
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• pp.633-642
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• 2005

Nucleate pool boiling experiments for R11 under a constant wall temperature condition were carried out. A microscale heater array was used for the heating and the measurement of high temporal and spatial resolution by the Wheatstone bridge circuit. Very sensitive heat flow rate data were obtained by the control for the surface condition with high time resolution. The measured heat flow rate shows a discernable peak at the initial growth stage and reaches an almost constant value. In the thermal growth region, bubble shows a growth proportional to $t^{\frac{1}{5}}$. The bubble growth behavior is analyzed with a dimensionless parameter to compare with the previous results in the same scale. As the wall superheat increases, the departure diameter and the departure time increase, and the waiting time decreases. But the asymptotic growth rate is not affected by the wall superheat change. The effect of the wall superheat is resolved into the suggested growth equation. Dimensionless parameters of time and bubble radius characterize the thermal growth behavior well, irrespective of wall condition. The comparison between the result of this study and the previous results shows a good agreement at the thermal growth region. The quantitative analysis for the heat transfer mechanism is conducted with the measured heat flow rate behavior and the bubble growth behavior. The required heat flow rate for the volume change of the observed bubble is about twice as much as the instantaneous heat flow rate supplied from the wall.

• Journal of Plant Biotechnology
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• 제31권3호
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• pp.249-253
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• 2004

생물반응기의 형태에 따른 인삼부정근의 생장과 ginsen-side의 생산능력에 대하여 조사한 결과, 원형의 상부와 하부에 5 cm의 bubble column을 가진 bulb type bubble bioreactor (BU)에서 건물중은 41.92 g으로 가장 많이 증가하였으며, cylindric tube bioreactor (CT)에서 건물중이 38.55g으로 가장 낮게 나타났다. 이들 두 생물반응기의 초기 kLa 값은 BU 생물반응기에서 6.98 h$^{-1}$로 가장 높게 측정되었고, 반대로 bubble column이 없는 CT 생물반응기에서 5.25 h$^{-1}$으로 가장 낮게 측정되었다. 그러나 이와 같은 초기 kLa값의 차이는 부정근내의 이차대사산물인 ginsenoside의 함량에는 영향을 주지 않는 것으로 나타났다. 또한 BU 생물반응기에서 bubble column의 길이를 기존의 5 cm에서 10 cm로 연장시켰을 때, 초기 kLa값이 6.52 h$^{-1}$에서 7.80 h$^{-1}$로 증가하면서 인삼부정근의 생장을 42.13 g에서 50.30 g으로 약 16% 증가시킨 것으로 나타났다.

• 대한기계학회논문집
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• 제19권2호
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• pp.418-426
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• 1995

A bubble-powered microactuator is designed conceptually. And the actuation mechanism due to bubble growth and collapse is studied numerically and analytically. In this analysis, it is estimated that the time lag for bubble formation on micro line heater, the duration of the bubble growth and collapse and the pressure change in actuator due to the bubble evolution. Based on these calculations, the actuator control scheme is visualized. This actuator may be applicable to the system which needs to pump liquid correctly and regularly.

• Korea-Australia Rheology Journal
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• 제11권3호
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• pp.247-253
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• 1999

The growth of a spherical vapor bubble contained in a large body of upper convected Maxwell fluid is theoretically analyzed under the devolatilization condition of polymer by using a Galerkin FEM in the Lagrangian frame. Using the finite element technique, a fully explicit numerical scheme is developed both for the calculation of pressure distribution and for the tracking of bubble surface. Oscillatory behavior in bubble radius is observed during growth and the oscillatory behavior is found to be due to the interaction of mass transfer resistance and elasticity. It is found that the elasticity of fluid accelerates the growth and removal of volatile component. It is also found that the bubble growth in the devolatilization of polymers is affected by both mass transfer resistance and viscoelasticity of fluids.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2008년 영문 학술대회
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• pp.700-710
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• 2008

A Bubble size distribution model has been developed for the numerical simulation of cryogenic high-speed cavitating flow of the turbo-pumps in the liquid fuel rocket engine. The new model is based on the previous one proposed by the authors, in which the bubble number density was solved as a function of bubble size at each grid point of the calculation domain by means of Eulerian framework with respect to the bubble size coordinate. In the previous model, the growth/decay of bubbles due to pressure difference between bubble and liquid was solved exactly based on Rayleigh-Plesset equation. However, the unsteady heat transfer between liquid and bubble, which controls the evaporation/condensation rate, was approximated by a theoretical solution of unsteady heat conduction under a constant temperature difference. In the present study, the unsteady temperature field in the liquid around a bubble is also solved exactly in order to establish an accurate and efficient numerical simulation code for cavitating flows. The growth/decay of a single bubble and growth of bubbles with nucleation were successfully simulated by the proposed model.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 춘계학술대회
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• pp.1891-1896
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• 2003

The bubble motion during nucleate boiling in a microchannel is investigated numerically. The liquid-vapor interface is tracked by a level set method which is modified to include the effects of phase change at the interface and contact angle at the wall. The computations are made for various channel sizes, liquid flow rates, and contact angles. Based on the numerical results, the bubble growth pattern and its effect on the flow and heat transfer are discussed.

• 생명과학회지
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• 제12권5호
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• pp.577-583
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• 2002

$\beta$-glucuronidase 유전자를 형질전환한 담배에서 여러 조직중에서 가장 activity가 높은 줄기에서 현탁세포를 유도하여 생장 및 발현 양상을 조사하였다. Flask culture와 2.5 L bubble column culture시 세포의 성장에는 큰 차이가 없었지만 $\beta$-glucuronidase의 발현은 bubble column culture시 약 2850 U/mg으로 95배 향상되는 결과를 나타내었다. 하지만 두 경우 모두 $\beta$-glucuronidase의 생산량이 증가와 감소를 반복하는 양상을 나타내었다. 이것은 외래 단백질의 생산과 파괴가 반복적으로 일어나는 것으로 추정이 된다. 또한 bubble column culture의 생산성을 향상시키기 위해 중요한 영양분인 sucrose을 30 g/L로 두 번 첨가한 경우, 다른 영양분의 고갈로 인하여 세포의 최종 생산량은 향상되지가 않았고 $\beta$-glucuronidase는 안정적으로 생산되었지만 최종 생산량은 향상되지가 않았다. 하지만 세포의 크기가 감소하여 배양기 운전이 쉬워지는 장점이 있었고 이것은 세포의 고농도 배양을 통한 재조합 단백질 생산성을 향상시키는 유리하게 작용할 것이다.

• 대한기계학회논문집B
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• 제28권8호
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• pp.996-1003
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• 2004

The bubble motion during nucleate boiling in a microchannel is investigated by numerically solving the equations governing conservation of mass, momentum and energy in the liquid and vapor phases. The liquid-vapor interface is tracked by a level set method which is modified to include the effects of phase change at the interface and contact angle at the wall. Also, the evaporative heat flux from the thin liquid film that forms underneath a growing bubble attached to the wall is incorporated in the analysis. Based on the numerical results, the effects of channel size, contact angle, wall superheat and waiting period on the bubble growth and heat transfer in a microchannel are quantified.

• 한국가시화정보학회지
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• 제12권1호
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• pp.13-17
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• 2014

The growth of micro bubble has been simulated under the variation of ambient pressure. The Rayleigh-Plesset equation governs the dynamic growth and collapse of a bubble according to pressure and temperature conditions. The Rayleigh-Plesset equation was solved by 4th-order Runge-Kutta method for wide range of pressure variations. As numerical parameters, the pressure difference between initial and final pressures, and the temporal pressure gradient are changed. The results show that the pressure difference has little effect on the growth rate of the micro bubble in the inertia controlled growth region. On the other hand, the growth rate increases linearly with the increase of the pressure gradient.

• 대한기계학회논문집B
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• 제29권5호
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• pp.643-652
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• 2005

Saturated nucleate pool boiling experiments for binary mixtures, which are consisted of refrigerant R11 and R113, were performed with constant wall temperature condition. Results for binary mixtures were also compared with pure fluids. A microscale heater array and Wheatstone bridge circuits were used to maintain the constant temperature of the heating surface and to obtain heat flow rate measurements with high temporal and spatial resolutions. Bubble growth images were captured using a high speed CCD camera synchronized with the heat flow rate measurements. The departure time for binary mixtures was longer than that for pure fluids, and binary mixtures had a higher onset of nucleate boiling (ONB) temperature than pure fluids. In the asymptotic growth region, the bubble growth rate was proportional to a value between $t^{\frac{1}{6}}$ and $t^{\frac{1}{4}}$. The bubble growth behavior was analyzed to permit comparisons with binary mixtures and pure fluids at the same scale using dimensionless parameters. There was no discernable difference in the bubble growth behavior between binary mixtures and pure fluids for a given ONB temperature. And the departure radius and time were well predicted within a ${\pm}30{\%}$ error. The minimum heat transfer coefficient of binary mixtures occurred near the maximum ${\mid}y-x{\mid}$ value, and the average required heat flux during bubble growth did not depend on the mass fraction of R11 as more volatile component in binary mixtures. Finally, the results showed that for binary mixtures, a higher ONB temperature had the greatest effect on reducing the heat transfer coefficient.