• Molecules and Cells
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• 제27권6호
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• pp.657-665
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• 2009

The ovomucoid pre-mRNA has been folded into mini-hairpins adaptable for the RNA recognition motif (RRM) protein binding. The number of mini-hairpins were 372 for pre-mRNA and 83-86 for mature mRNA. The spatial arrangements are, in average, 16 nucleotides per mini-hairpin which includes 7 nt in the stem, 5.6 nt in the loop and 3.7 nt in the inter-hairpin spacer. The constitutive splicing system of ovomucoid-pre-mRNA is characterized by preferred order of intron removal of 5/6 > 7/4 > 2/1 > 3. The 5' splice sites (5'SS), branch point sequences (BPS) and 3' splice sites (3'SS) were identified and free energies involved have been estimated in 7 splice sites. Thermodynamic barriers for splice sites from the least (|lowest| -Kcal) were 5, 4, 7, 6, 2, 1, and 3; i.e., -18.7 Kcal, -20.2 Kcal, -21.0 Kcal, -24.0 Kcal, - 25.4 Kcal, -26.4 Kcal and -28.2 Kcal respectively. These are parallel to the kinetic data of splicing order reported in the literature. As a result, the preferred order of intron removals can be described by a consideration of free energy changes involved in the spliceosomal assembly pathway. This finding is consistent with the validity of hnRNP formation mechanisms in previous reports.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 추계학술대회 논문집 전력기술부문
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• pp.12-14
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• 2007

A voltage transformer (VT) is used to transform a high voltage into a low voltage as an input for a metering device or a protection relay. VTs use an iron core which maximizes the flux linkage. The primary current of the VT has non-fundamental components caused by the hysteresis characteristics of the iron core. It causes a voltage drop in the winding impedances resulting in the error of the VT. This paper describes a compensation algorithm for the VT. The proposed algorithm can compensate the secondary voltage of VT by calculating the primary current from the exciting current of the hysteresis loop in the voltage transformer. In this paper, the exciting branch was divided into a non-linear core loss resistor and a non-linear magnetizing inductor. The performance of the proposed algorithm was validated under various conditions using EMTP generated data. Test results show that the proposed compensation algorithm can improve the accuracy of the VT significantly.

• 한국광과학회:학술대회논문집
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• 한국광과학회 2003년도 학술대회지
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• pp.97-103
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• 2003

Phytochrome controls diverse aspects of plant development in response to the ambient light conditions. HFRl, a basic helix-loop-helix protein, is required for a subset of phytochrome A (phy A)-mediated photo-responses in Arabidopsis. Here, we show that overexpression of HFR1-N105, but not the one of the full-length HFR1, confers exaggerated photo-responses. The transgenic plants overexpressing HFR1- N105 exhibited light-independence in a subset of photo-responses, including germination, de-etiolation, gravitropic hypocotyl growth, and blocking of greening. Overexpression of HFR1-N105 also caused constitutive light-responses in the expression of some light-regulated genes. In addition, the HFR1-N105 overexpressor showed hypersensitive responses under R and FR light, dependently on phyB and phyA, respectively. End-of-day far-red light response and petiole elongation were suppressed in the HFR1-N105 overexpressor plants. Together these results imply that overexpression of HFR1-N105 activated a branch of light signaling, supporting the hypothesis that transcriptional regulation in the nucleus would be the primary mechanism of light signaling in Arabidopsis. We discuss the biotechnological potential of the mutant bHLH protein, HFR1-N105 in regard to suppressed shade avoidance syndrome.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2014년도 춘계학술발표대회
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• pp.12-14
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• 2014

하드웨어가 해저드(hazard) 검출을 지원하지 않는 멀티이슈 VLIW 프로세서의 성능을 높이기 위해서는 컴파일러가 명령어 의존성과 하드웨어 자원의 제약을 지키는 범위 안에서 최대한 명령어수준 병렬성(ILP)을 활용하는 것이 중요하다. 기본 블록(basic block) 스케쥴링은 Branch 등 제어 흐름(control flow)의 경계를 넘어선 스케쥴링을 행하지 않아 그 효과가 제한적이다. 소프트웨어 파이프라이닝(software pipelining)은 루프(loop)의 경계를 허물어 여러반본(iteration)의 명령어가 동시에 수행되도록 하는 것으로 모듈로 스케쥴링(modulo scheduling)은 그 중에 한 범주의 스케쥴링 기법들을 일컫는다. 본 연구에서는 그 중 한가지인 스윙 모듈로 스케쥴러(swing modulo scheduler)[1]를 구현하여 그 효과를 알아보고자 한다.

• Steel and Composite Structures
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• 제45권3호
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• pp.455-466
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• 2022

Despite the considerable lateral stiffness and strength of the Concentrically Braced Frame (CBF), it suffers from low ductility and low seismic dissipating energy capacity. The buckling of the diagonal members of the CBF systems under cyclic loading ended up to the shortcoming against seismic loading. Comprehensive researches have been performing to achieve helpful approaches to prevent the buckling of the diagonal member. Among the recommended ideas, metallic damper revealed a better success than other ideas to enhance the behavior of CBFs. While metallic dampers improve the behavior of the CBF system, they increase constructional costs. Therefore, in this paper, a new steel damper with flexural mechanism is proposed, which is investigated experimentally and numerically. Also, a parametrical revision was carried out to evaluate the effect of thickness, slenderness ratio, angle of the main plate, and height of the main plates on the proposed damper. For the parametrical study, 45 finite element models were analyzed and considered. Experimental results, as well as the numerical results, indicated that the proposed damper enjoys a stable hysteresis loop without any degradation up to a high rotation equal to around 31% that is significantly considerable. Moreover, it showed a suitable performance in case of ductility and energy dissipating. Besides, the necessary formulas to design the damper, the required relations were proposed to design the elements outside the damper to ensure the damper acts as a ductile fuse.

• 전자공학회논문지C
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• 제35C권12호
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• pp.66-76
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• 1998

본 논문에서는 명령어 버퍼에 저장되어 있는 가변 길이 명령어의 미스 율을 낮추기 위한 버퍼를 구현한다. 또한 반복적으로 수행되는 명령어들의 디코딩 시간을 줄이기 위해 외부에서 명령어를 패취(fetch)하여 초기 디코드 동작을 한 후 그 결과를 버퍼에 저장하는 MAU(Mark Appending Unit)를 둔다. 또한 분기명령어의 효과적인 처리를 위해 타겟 명령어의 히트 여부를 판단하는 회로를 내장하고 있다. 가변 길이 명령어를 처리하기 위한 각 모듈은 VHDL을 이용해 설계되었으며, Model Technology Inc.의 V-System를 사용하여 시뮬레이션 하였다. 합성 및 검증은 0.6㎛ 5-Volt CMOS TLM(Three Layer Metal) COMPASS 라이브러리를 이용한 ASIC Synthesizer 툴을 사용하였다. 최고 동작 속도는 약 140MHz까지이며, 총 게이트 수는 약 17,000개이다.

• 대한두개안면성형외과학회지
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• 제20권6호
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• pp.421-424
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• 2019

Osteomas are benign, slow-growing osteogenic lesions frequently found in the craniomaxillofacial region. They can be classified as peripheral, central, or extraskeletal. Reactive mechanisms to trauma or infection, as well as muscle traction, are thought to play a major role in the development of peripheral osteomas. In the present report, a 41-year-old woman presented with a slowgrowing, painless mass on her left eyebrow. She had suffered trauma 15 years prior. In the computed tomography scan, a 2.5×2×0.7-cm radio-opaque tumor was detected just medial to the left supraorbital foramen, and a peripheral osteoma was clinically diagnosed. An elective operation under general anesthesia was planned. Following a suprabrow incision, subcutaneous and intramuscular dissection was performed. In the surgical plane deep to the corrugator muscles and superficial to periosteum, a branch of the supratrochlear nerve was encountered and preserved using a vessel loop. The osteoma beneath the periosteum was extracted in multiple fragments using a chisel and mallet to minimize trauma to the nerve. Contour and facial symmetry were corrected. To use a suprabrow incision, the surgeon must understand neighboring anatomical structures, including the course of the supratrochlear and supraorbital neurovascular bundles. When these structures are located adjacent to tumor lesions, careful surgical maneuvers should be performed to preserve them.

• 컴퓨터교육학회논문지
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• 제18권2호
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• pp.71-81
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• 2015

EISC 프로세서에서 LERI 폴딩과 루프 버퍼링을 지원하는 명령어 큐는 하드웨어적으로 20%를 차지하며, 그 효율성은 성능에 직결된다. 본 연구에서는 EISC 프로세서의 명령어 큐 아키텍처 효율성 향상을 복귀주소 스택(RAS)을 통해 실현하였다. 구현한 아키텍처는 EISC의 얕은 파이프라인 구조의 이점을 활용하여 잘못된 명령어 수행으로 인한 RAS Corruption 문제를 제거하였다. 실험에서, 4개 엔트리의 RAS는 명령어 큐의 플러시를 기존보다 최대 58.90% 줄였고, 8개 엔트리의 RAS는 이를 최대 61.28% 줄였다. 또한 실험 결과 8개 엔트리의 RAS는 3.47%의 성능향상을 보여주었고, 4개 엔트리의 RAS는 3.15%의 성능향상을 보여주었다.

• 한국전산구조공학회논문집
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• 제35권6호
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• pp.381-386
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• 2022

본 논문에서는 휨 항복 메커니즘을 기반으로 한 강재이력 댐퍼를 제안하기 위한 해석 및 실험적 연구를 수행하였다. 댐퍼는 휨모멘트에 의한 항복거동을 하도록 설계된 일련의 댐핑 플레이트로 구성된다. 실험 결과와 유한요소해석 결과의 비교를 통해서 본 연구에서 채택된 해석적 접근방식이 댐핑 플레이트의 형태 및 상세에 대한 민감도 연구를 수행하기에 적절함을 확인하였다. 최초에 제안된 댐퍼는 휨 항복 메커니즘을 기반으로 작동하는 것으로 고안되었으나, 댐핑 플레이트의 인장 거동에 대한 기여도가 상당할 수 있음을 관찰할 수 있었다. 댐핑 플레이트의 두께가 증가함에 따라 휨 항복에 의한 에너지 흡수량이 증가한다. 댐핑 플레이트의 두께가 감소함에 따라 인장에 의한 댐퍼의 비선형 거동 기여도가 증가하고 좌굴 발생으로 인하여 이력곡선의 형상이 댐퍼로서 불리해진다.

• Earthquakes and Structures
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• 제23권2호
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• pp.129-138
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• 2022

One of the objectives to prevent building pounding between two adjacentstructures is to considerseparation distance or decrease relative displacement during seismic excitation. Although the majority of building codes around the world have basically suggested some equations or approximately recommended various distances between structuresto avoid pounding hazard, but a lot of reportsin zone of pounding have obviously shown thatsafety situation or economic consideration are not always provided due to the collisions between buildings and the cost of land, respectively. For this purpose, a dynamic MDOF model by having base isolation system is numerically considered and using various earthquake records, relative displacements are mathematically investigated. Different equations to determine the value of damping ratio are collected and the results of evaluations are listed for comparison among them to present a new equation for determination of impact damping ratio. Presented equation is depends significantly on impact velocity before and after impact based on artificial neural network, which the accuracy of them is investigated and also confirmed. In order to select the optimum equation, hysteresisloop of impact between base of building and rubber bumper is considered and compared with the hysteresis loop of each impact, calculated by different equations. Finally, using representative equation, the effect of thickness, number and stiffness of rubber bumpers are numerically investigated. The results of analysis indicate that stiffness and number of bumpers have significantly affected in zone of impact force while the thickness of bumpers have not shown significant influence to calculate impact force during earthquake. For instance, increasing the number of bumpers, gap size between structures and also the value of stiffness is caused to decrease impact force between models. The final evaluation demonstrates that bumpers are able to decrease peak lateral displacement of top story during impact.