• 대한핵의학회지
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• 제38권3호
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• pp.209-217
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• 2004

Evaluation of dementia in patients with early symptoms of cognitive decline is clinically challenging, but the need for early, accurate diagnosis has become more crucial, since several medication for the treatment of mild to moderate Alzheimer' disease are available. Many neurodegenerative diseases produce significant brain function alteration even when structural imaging (CT or MRI) reveal no specific abnormalities. The role of PET and SPECT brain imaging in the initial assessment and differential diagnosis of dementia is beginning to evolve vapidly and growing evidence indicates that appropriate incorporation of PET into the clinical work up can improve diagnostic and prognostic accuracy with respect to Alzheimer's disease, the most common cause of dementia in the geriatric population. in the fast few years, studios comparing neuropathologic examination with PET have established reliable and consistent accuracy for diagnostic evaluations using PET - accuracies substantially exceeding those of comparable studies of diagnostic value of SPECT or of both modalities assessed side by side, or of clinical evaluations done without nuclear imaging. This review deals the role of functional brain imaging techniques in the evaluation of dementias and the role of nuclear neuroimaging in the early detection and diagnosis of Alzheimer's disease.

• 대한방사선기술학회지:방사선기술과학
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• 제46권4호
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• pp.295-301
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• 2023

In addition to protocol adjustments during CT examinations, the height of the CT table can also affect image quality. Therefore, this study aimed to investigate the change in image quality depending on the height of the table in brain CT, which accounts for a large proportion of CT examinations, by measuring signal to contrast to noise ratio (CNR) and noise power spectrum (NPS) using the head phantom and evaluating them. The head phantom images were acquired using Philips Brilliance iCT 256. When the image was acquired, the table height was adjusted to 815, 865, 915, 965, 1015, and 1030 mm, respectively, and each scan was performed 3 times for each height. The CNR result showed the highest value at 965 mm, which is the height adjacent to the center of the head phantom. NPS showed the lowest NPS at 915 mm, the center of the head phantom in the low frequency region. From these results, it can be seen that the height of the table in CT examination is closely related to the image quality, and it can be seen the characteristics of image quality according to CT table through quantitative evaluation methods such as CNR and NPS.

• Clinical Pain
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• 제20권1호
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• pp.39-42
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• 2021

A 29-year-old woman had 1-month history of back pain radiating into lower extremities, motor weakness, and sensory abnormalities in both lower extremities. Contrast-enhanced spinal magnetic resonance imaging (MRI) revealed a homogeneously enhancing mass at the T12~L1 and several intradural enhancing nodular lesions at L2~S1. Tumor resection surgery was performed and following histological examination showed that the tumor satisfied the diagnostic criteria for atypical choroid plexus papilloma (CPP). To find primary tumor sites, contrast-enhanced brain MRI, whole spine MRI, and PET-CT were carried out and additional lesions were detected at the fourth ventricle, right cerebellum, and upper thoracic spinal cord. This is a very rare case of metastatic atypical CPP that involves brain, upper thoracic spinal cord, and cauda equina with initial manifestation of radicular symptoms without clinical signs of primary brain lesion.

• International Journal of Computer Science & Network Security
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• 제23권11호
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• pp.183-189
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• 2023

A stroke is a medical disease where a blood vessel in the brain ruptures, causes damage to the brain. If the flow of blood and different nutrients to the brain is intermittent, symptoms may occur. Stroke is other reason for loss of life and widespread disorder. The prevalence of stroke is high in growing countries, with ischemic stroke being the high usual category. Many of the forewarning signs of stroke can be recognized the seriousness of a stroke can be reduced. Most of the earlier stroke detections and prediction models uses image examination tools like CT (Computed Tomography) scan or MRI (Magnetic Resonance Imaging) which are costly and difficult to use for actual-time recognition. Machine learning (ML) is a part of artificial intelligence (AI) that makes software applications to gain the exact accuracy to predict the end results not having to be directly involved to get the work done. In recent times ML algorithms have gained lot of attention due to their accurate results in medical fields. Hence in this work, Stroke disease identification system by using Machine Learning algorithm is presented. The ML algorithm used in this work is Artificial Neural Network (ANN). The result analysis of presented ML algorithm is compared with different ML algorithms. The performance of the presented approach is compared to find the better algorithm for stroke identification.

• 한국임상수의학회지
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• 제24권4호
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• pp.667-672
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• 2007

This report describes the use of conventional computed tomography(CT) for the diagnosis of head trauma in three canine patients. According to physical and neurologic examinations, survey radiography and computed tomography, these patients were diagnosed as traumatic brain injury. Especially, CT is the imaging modality of first choice for head trauma patients. It provides rapid acquisition of images, superior bone detail, and better visualization of acute hemorrhage than magnetic resonance imaging. It is also less expensive and more readily available. Pre-contrast computed tomography was used to image the head. Then, post-contrast CT was performed using the same technique. The Modified Glasgow Coma Scale(MGCS) score was used to predict their probability of survival rate after head trauma in these dogs. Computed tomogram showed fluid filled tympanic bulla, fracture of the left temporal bone and cerebral parenchymal hemorrhage with post contrast ring enhancement. However, in one case, computed tomographic examination didn't delineate cerebellar parenchymal hemorrhage, which was found at postmortem examination. Treatments for patients placed in intensive care were focused to maintain cerebral perfusion pressure and to normalize intracranial pressure. In these cases, diagnostic computed tomography was a useful procedure. It revealed accurate location of the hemorrhage lesion.

• Journal of Digestive Cancer Research
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• 제4권2호
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• pp.122-126
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• 2016

Leptomeningeal carcinomatosis occurs in approximately 5% of patients with cancer. The most common cancers involving the leptomeninges are breast, lung cancer and melanoma. However, gastric adenocarcinoma has been rarely reported with leptomeningeal carcinomatosis. The presenting manifestations are usually headache, visual disturbances and seizures. We report a case of leptomeningeal metastasis that presented as a gastric cancer. A 75-year old man was transferred to our hospital for further evaluation and treatment after being diagnosed with adenocarcinoma through endoscopic biopsy during a regular health examination. An abdominal computed tomography (CT) showed AGC, stage IA (cT1N0M0), while an endoscopic examination showed AGC, Borrmann type 2. The patient is currently under observation after undergoing radical subtotal gastrectomy with gastroduodenostomy and subsequent administration of oral chemotherapeutic agents. As an abdominal CT response assessment performed after surgery revealed new metastasis to the liver, the patient received palliative chemotherapy as recurrence was suspected. After receiving chemotherapy in the order of DP (Cisplatin + Docetaxel), FOLFIRI (5-FU + Leucovorin + Irinotecan), an abdominal CT response assessment showed complete response. Since decreased mentality maintained throughout the follow up period based on outpatient clinic, brain MRI was performed and revealed multiple leptomeningeal metastasis. The Patient died 2 days after the diagnosis.

• 한국방사선학회논문지
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• 제10권3호
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• pp.207-214
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• 2016

본 연구에서는 부산지역의 컴퓨터단층촬영검사실의 근무자를 대상으로 소아 두부 CT 검사를 시행함에 있어 방사선방어에 대한 지식정도와 행위에 대한 인식도 및 의식도를 설문조사하여 기관별로 분류하여 상급종합병원, 종합병원, 병원간의 인식도와 의식도 점수를 비교하여 영향을 미치는 요인이 무엇인지 알아보고자 하였다. 연구결과 기관별 인식도 평균점수는 상급종합병원이 42.29, 종합병원 38.43, 병원 34.06으로 상급종합병원이 가장 높게 나타났으며 종합병원, 병원 순으로 나타났다. 기관별 의식도 평균점수는 상급종합병원이 21.37, 종합병원 24.68, 병원 29.19로 병원이 가장 높은 것으로 나타났으며 종합병원, 상급종합병원 순으로 나타났다. 따라서 종합병원이나 병원의 CT 근무자들의 인식도를 높이기 위해서는 보수교육 및 학회 등을 통해 방사선에 대한 인식을 함양시키려는 노력이 필요할 것으로 사료되며 또한 상급종합병원의 CT 근무자들의 의식도를 높이기 위해서 방사선 방어의 최적화를 모색하고 환자에 대한 방사선 피폭선량 감소에 대해 노력을 기울여야 할 것으로 판단된다.

• 한국융합학회논문지
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• 제6권5호
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• pp.287-294
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• 2015

본 연구의 목적은 급성기 허혈성 뇌졸중 환자의 뇌 관류 CT검사 시 피폭선량을 알아보고자 하였다. 특히, 방사선 감수성이 높은 장기들의 장기선량(Organ dose)을 팬텀과 유리선량계를 이용하여 실측해보고, 제조사가 제시한 기존 프로토콜(고정시간기법)과 새로 제시한 융합 프로토콜(조영제 추적기법)을 적용하여 선량을 측정하여 보고, 피폭선량 저감화 방안을 마련하고자 하였다. 분석결과 기존 프로토콜과 비교하여 새로 제시한 융합 프로토콜에서 최고 39.8 %, 최저 5.8 % 장기선량이 감소하였고, 검사 피폭선량인 $CDTI_{vol}$과 DLP 값은 각각 25 % 감소하였으며, 권고 선량 이하로 측정되었다. 위의 분석결과를 바탕으로 기존에 제시된 프로토콜을 점검해보고, 새로 제시한 융합 프로토콜을 적용하여 피폭선량을 감소시켜 국민보건향상에 이바지 해야 할 것이며, 다른 검사에서도 최적의 프로토콜을 찾기 위한 연구가 계속되어져야 할 것으로 사료된다.

• 혜화의학회지
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• 제15권1호
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• pp.1-9
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• 2006

For this study, we carried out dementia assessment examination of 74 patients with memory disturbance who have come to Cheongju oriental hospital of Daejeon university from April 2005 to February 2006. This study classified the patients as none-dementia(ND), questionable dementia(QD), and dementia(DA) groups and analyzed the result of examination. As a result, the following conclusion was drawn. 1. Among the 3 groups, there was no significant differences in the sex distribution. But according to age distribution, the age of QD and DA groups showed significant difference from that of ND group. 2. MMSE-K and HDS-K scores showed the significant differences among all groups, and 7 MS result showed the significant difference between ND and the other groups. 3. The DA group significantly got lower scores than ND group in the items of the MMSE-K, Orientation, Registration, Recall, Attention, Copy two pentagons and Comprehension. Especially, significant difference also was shown in the orientation item between QD and DA groups. 4. The scores in the items of 7 MS, Benton temporal orientation, Enhanced cued recall and Clock drawing showed significant difference among all groups. Category fluency score showed significant difference between ND and the other groups. 5. The results of Brain CT and clinical chemistry test didn't show significant difference among all groups.

• 대한방사선기술학회지:방사선기술과학
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• 제32권3호
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• pp.307-312
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• 2009

CT 검사에서 수정체 차폐용 비스무트(bismuth)를 사용하여 수정체 선량의 감소효과를 유리선량계로 측정하여 비스무트 차폐효과 및 영상을 평가하였다. 안구 및 두부 CT 검사에서 차폐용 비스무트를 사용하여 수정체 선량의 감소와 차폐 효과를 평가하기 위해 인체모형 팬텀으로 유리선량계를 이용하여 수정체 선량을 평가하였다. 유리선량계를 이용하여 비스무트를 사용하기 전의 평균 선량은 21.54 mGy이었고, 사용 후의 선량은 10.46 mGy로 51.3%의 선량 감소효과가 있다. 차폐용 비스무트를 사용한 안구 64 MDCT 촬영에서 선량감소 효과가 있어 수정체를 포함한 안구 CT 스캔에서는 비스무트를 사용하여 검사하도록 권고한다.