• Journal of the Korea Concrete Institute
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• v.21 no.6
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• pp.745-752
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• 2009

This paper presents the optimized mixing design of lightweight aerated concrete using hydrogen peroxide. Design of experiments in order to the optimized mixing design was applied and commercial program (MINITAB) was used. Statistical analysis was used to Box-Behnken (B-B) method in response surface analysis. The influencing factors of experimental are unit cement content, water ratio and hydrogen peroxide ratio. According to the analysis of variance, at the hardened state, water ratio and hydrogen peroxide ratio affects on dried density, compressive strength and bending strength of lightweight aerated concrete, but unit cement content affects on only dried density. In the results of response surface analysis, to obtain goal performance, the optimized mixing design for lightweight aerated concrete using hydrogen peroxide were unit cement content of 800 kg/$m^3$, water ratio of 44.33% and hydrogen peroxide ratio of 10%.

• International Journal of Highway Engineering
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• v.15 no.6
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• pp.69-78
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• 2013

PURPOSES : In this study blast furnace slag, an industrial byproduct, was used with an activating chemicals, $Ca(OH)_2$ and $Na_2SiO_3$ for carbon capture and sequestration as well as strength development. METHODS : This paper presents the optimized mixing design of Carbon-Capturing and Sequestering Activated Blast-Furnace Slag Mortar. Design of experiments in order to the optimized mixing design was applied and commercial program (MINITAB) was used. Statistical analysis was used to Box-Behnken (B-B) method in response surface analysis. RESULTS : The influencing factors of experimental are water ratio, Chemical admixture ratio and Curing temperature. In the results of response surface analysis, to obtain goal performance, the optimized mixing design for Carbon-Capturing and Sequestering Activated Blast-Furnace Slag Mortar were water ratio 40%, Chemical admixture ratio 58.78% and Curing temperature of $60^{\circ}C$. CONCLUSIONS : Compared with previous studies of this experiment is to some extent the optimal combination is expected to be reliable.

• Journal of the Korea institute for structural maintenance and inspection
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• v.17 no.6
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• pp.130-137
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• 2013

This research was performed through the experimental design to get the statistical analysis on foamed concrete mixed plaster with hydrogen peroxide. In this experiment, we set the ratio of each material, which part of lightweight concrete, as experimental factors and evaluated on the mechanical properties by statistical analysis for response variables obtained from experiments. Experimental factors are plaster replacement, water binder ratio, and hydrogen peroxide ratio. Response variables are dry density, compressive strength, and flexural strength. Mixing design of the foamed concrete set up a total of 15 experimental points by Box-Behnken (BB) method of the response surface analysis. Thus, the results of a study were summarized as follows. Values of the probability in experimental factors (plaster replacement, water binder ratio and hydrogen peroxide ratio) on the response variables were estimated to be significant at the 95% of confidence limit. On response surface analysis for dry density of foamed concrete, water binder ratio and hydrogen peroxide ratio were estimated to be significant (${\alpha}$ = 0.05), and the relationship between the amount of void and the water content for dry density is inverse proportional. On response surface analysis for the compressive strength of foamed concrete, water binder ratio, hydrogen peroxide ratio and (hydrogen peroxide ratio)$^2$ was estimated to be significant (${\alpha}$ = 0.05). On response surface analysis for the flexural strength of foamed concrete, water binder ratio, hydrogen peroxide ratio was estimated to be significant (${\alpha}$ = 0.05). Through multi response surface analysis, we found the optimal area that meets performance goals.

• Journal of Microbiology and Biotechnology
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• v.23 no.8
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• pp.1084-1091
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• 2013

In this paper, two statistical methods were applied to optimize medium components to improve the production of the milk-clotting enzyme by Bacillus amyloliquefaciens D4. First, wheat bran juice, skim milk powder, and $Na_2HPO_4$ were shown to have significant effects on D4 enzyme production using the Plackett-Burman experimental design. Subsequently, an optimal medium was obtained using the Box-Behnken method, which consisted of 3.31 g/l of skim milk powder, 5.0 g/l of sucrose, 0.1 g/l of $FeSO_4{\cdot}7H_2O$, 0.1 g/l of $MgSO_4{\cdot}7H_2O$, 0.1 g/l of $MnSO_4{\cdot}2H_2O$, 0.1 g/l of $ZnSO_4{\cdot}7H_2O$, 1.52 g/l of $Na_2HPO_4$, and 172.45 g/l of wheat bran juice. With this optimal medium, the milk-clotting enzyme production was remarkably enhanced. The milk-clotting enzyme activity reached 3,326.7 SU/ml after incubation of 48 h, which was 1.76-fold higher than that of the basic medium, showing that the Plackett-Burman design and Box-Behnken response surface method are effective to optimize medium components, and B. amyloliquefaciens D4 possessed a high rennet-producing capacity in the optimal medium.

• Korean Journal of Food Science and Technology
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• v.53 no.6
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• pp.739-748
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• 2021

This study focuses on the use of rice in the production of gluten-free rice udon (GFU) through an optimized mixing ratio, using the Box-Behnken response surface methodology (RSM). Different additional levels of rice flour (A, 40-60 g), acetylated distarch adipate (B, 10-20 g), and trehalose (C, 0-3 g) were used as variables, while water absorption level, volume, cooking loss, solid yield, lightness, texture properties, proximate compositions of GFU and turbidity of cooking water were set as responses in the RSM design model. The optimum mixing ratio for the preparation of gluten-free rice udon was obtained for 60.00 g of rice flour, 18.81 g of acetylated distarch adipate without the addition of trehalose. The response values of the optimized samples were water absorption (60.94%), volume (34.94%), turbidity of the cooking water (0.37), cooking loss (4.77%), solid yield (1.55 g), lightness value (70.04), hardness (2.53 N), springiness (0.18), gumminess (10.45 N), chewiness (1.83 N), and cohesiveness (2.89). This study has shown that rice flour can replace wheat flour to manufacture udon at an optimized mixing ratio successfully derived by statistical estimation method.

• Journal of Microbiology and Biotechnology
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• v.27 no.7
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• pp.1209-1215
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• 2017

Microwave sterilization was performed to inactivate the spores of biofilms of Bacillus cereus involved in foodborne illness. The sterilization conditions, such as the amount of water and the operating temperature and treatment time, were optimized using statistical analysis based on 15 runs of experimental results designed by the Box-Behnken method. Statistical analysis showed that the optimal conditions for the inactivation of B. cereus biofilms were 14 ml of water, $108^{\circ}C$ of temperature, and 15 min of treatment time. Interestingly, response surface plots showed that the amount of water is the most important factor for microwave sterilization under the present conditions. Complete inactivation by microwaves was achieved in 5 min, and the inactivation efficiency by microwave was obviously higher than that by conventional steam autoclave. Finally, confocal laser scanning microscopy images showed that the principal effect of microwave treatment was cell membrane disruption. Thus, this study can contribute to the development of a process to control food-associated pathogens.