• 제목/요약/키워드: Botswana

검색결과 33건 처리시간 0.026초

Anti-Diabetic Effects of an Ethanol Extract of Cassia Abbreviata Stem Bark on Diabetic Rats and Possible Mechanism of Its Action - Anti-diabetic Properties of Cassia abbreviata -

  • Bati, Keagile;Kwape, Tebogo Elvis;Chaturvedi, Padmaja
    • 대한약침학회지
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    • 제20권1호
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    • pp.45-51
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    • 2017
  • Objectives: This study aimed to evaluate the hypoglycemic effects of an ethanol extract of Cassia abbreviata (ECA) bark and the possible mechanisms of its action in diabetic albino rats. Methods: ECA was prepared by soaking the powdered plant material in 70% ethanol. It was filtered and made solvent-free by evaporation on a rotary evaporator. Type 2 diabetes was induced in albino rats by injecting 35 mg/kg body weight (bw) of streptozotocin after having fed the rats a high-fat diet for 2 weeks. Diabetic rats were divided into ECA-150, ECA-300 and Metformin (MET)-180 groups, where the numbers are the doses in mg.kg.bw administered to the groups. Normal (NC) and diabetic (DC) controls were given distilled water. The animals had their fasting blood glucose levels and body weights determined every 7 days for 21 days. Oral glucose tolerance tests (OGTTs) were carried out in all animals at the beginning and the end of the experiment. Liver and kidney samples were harvested for glucose 6 phosphatase (G6Pase) and hexokinase activity analyses. Small intestines and diaphragms from normal rats were used for ${\alpha}-glucosidase$ and glucose uptake studies against the extract. Results: Two doses, 150 and 300 mg/kg bw, significantly reduced the fasting blood glucose levels in diabetic rats and helped them maintain normal body weights. The glucose level in DC rats significantly increased while their body weights decreased. The 150 mg/kg bw dose significantly increased hexokinase and decreased G6Pase activities in the liver and the kidneys. ECA inhibited ${\alpha}-glucosidase$ activity and promoted glucose uptake in the rats' hemi-diaphragms. Conclusion: This study revealed that ECA normalized blood glucose levels and body weights in type 2 diabetic rats. The normalization of the glucose levels may possibly be due to inhibition of ${\alpha}-glucosidase$, decreased G6Pase activity, increased hexokinase activity and improved glucose uptake by muscle tissues.

Determinants of Adoption and Use of Open Access Publishing by Academic Staff in Nigeria Universities

  • Bashorun, Musediq Tunji;Jain, Priti;Sebina, Peter M.;Kalusopa, Trywell
    • Journal of Information Science Theory and Practice
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    • 제4권4호
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    • pp.49-63
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    • 2016
  • The emergence of the World Wide Web (WWW) has changed the scholarly publishing system. Today, Open Access (OA) scholarly publishing offers free access and wide dissemination for research findings anytime and anywhere as an additional value for scholarly content. Despite the potentials of OA publishing, its adoption and use is still low.This paper determines factors influencing the adoption and use of OA publishing by academic staff in universities in Nigeria using an adapted Unified Theory of Acceptance and Use Technology (UTAUT). The study applies methodological triangulation by combining quantitative and qualitative approaches. The empirical data were collected from 317 academic staff in universities in southwest Nigeria. The questionnaire forms were analyzed using the Statistical Package for Social Sciences (IBM-SPSS) 19.0 version to generate descriptive statistics, Analysis of Variance, and Hierarchical Multiple Regression. Thematically, analysis also applies to the interviews. The results show that awareness, attitude, performance expectancy, Internet self-efficacy, and facilitating conditions significantly influenced the adoption and use of OA publishing. The study also reveals that due to lack of OA policy, most of the respondents did not know about OA. The findings further establish that all predictors and moderating variables jointly contributed 64.4% total variance towards the adoption and use of OA publishing. One of the implications of this study is that there is a need for adequate facilities to support adoption and use of OA publishing. The findings inform the proposed framework for improving and evaluating the adoption and use of OA publishing. The findings also have theoretical, societal, and methodological significance to all stakeholders.

Technological Experience and Crop Production in Dryland Farming Systems in Africa : The Case of Draught Animal Power in Ghana

  • Panin, Anthony
    • 한국농업기계학회:학술대회논문집
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    • 한국농업기계학회 1993년도 Proceedings of International Conference for Agricultural Machinery and Process Engineering
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    • pp.591-600
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    • 1993
  • Considerable controversy exists about the trend of animal traction effects on crop production in dryland farming systems in sub-Saharan Africa (SSA). This problem arises on account of the failure of the few available empirical studies to recognise the important of technological experience of the individual adopting farmers. This study hence addresses this issue by examining the effects of experience in animal traction technology (ATT) on farm size, cropping emphasis, total crop output and farm productivity. It is based on farm management survey data on 42 small holder farm households fro Ghana. Thirty of these households used animal traction technology (ATT) fro crop cultivation and the rest, mainly hand-hoe. The animal traction sub-sample is classified into three groups according to farmers' years of experience with the technology , thus , those with 1-2, 3-10, and more than 10. Evidence from the study shows that the progression of years of experience with ATT leads to inten ification of labour and land use systems, enhancement of degree of motivation to enter into the market economy, increases in total crop output and farm productivity resulting for decreases in cultivated acreages. The implication of the findings is that institutioal and technical support that do accompany the introduction of such technologies should be structured to last for a relatively longer period to accomodate the learning process.

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Economic Growth and Animal Traction Development in Africa : An Empirical Analysis

  • Panin, A.
    • 한국농업기계학회:학술대회논문집
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    • 한국농업기계학회 1996년도 International Conference on Agricultural Machinery Engineering Proceedings
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    • pp.219-227
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    • 1996
  • Since the introduction of animal traction technologies(ATT) in many Sub Saharan Africa (SSA) countries, attempts to propagate its widespread use in the continent have suffered several setbacks. Many factors are responsible of this. However, developments in the African economies are believed to be a prominent factor. This study provides empirical evidence of the impact of economic growth on the performance of ATT-in Sub-Saharan Africa(SSa). The analysis uses 1971-1990 time-series data on ATT from botswana. The performance of ATT is measured on the basis of changes year covered under this study. The models used, are a regression model and a trend projection model. Although the regression model is representing a simplified view of the relationship between ATT and economic growth , it takes account of the influence of annual amounts of rainfall. It is concluded that economic growth has had a negative impact on the performance of ATT in Botwana. As the country's Gross Domestic Pro uct (GDP) steadily increased over the period of the analysis, the number of households using ATT declined at a rate of 2.5% per year. The impact of the GDP on ATT was directly associated with increases in the use of tractor, food imports and beef exports. The results have serious policy implications for agricultural development in many African countries that are not capable of sustaining their economic growth.

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Utilization of Sorghum Forage, Millet Forage, Veldt Grass and Buffel Grass by Tswana Sheep and Goats when Fed Lablab purpureus L. as Protein Supplement

  • Aganga, A.A.;Autlwetse, M.N.
    • Asian-Australasian Journal of Animal Sciences
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    • 제13권8호
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    • pp.1127-1132
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    • 2000
  • Forty yearling Tswana sheep and goats (20 sheep and 20 goats) of both sexes were used in a feeding trial conducted in Botswana College of Agriculture (B.C.A) Content Farm in Gaborone for three months. The animals were randomized into four treatment groups of five animals per species balancing for weight and sex such that average initial weights were not statistically different. The sheep and goats were individually housed and fed under a common roof. All the animals were fed on Lablab purpureus L. as a protein supplement which was 40% of the ration. In addition to L.purpureus L. the control groups of both species were fed on 60% Cenchrus ciliaris L. as basal diet. The other three treatment groups were fed on different forages namely; sorghum forage (Sorghum sudanense (Piper) Stapf), millet forage (Pearl millet, Pennisetum typhoides (Burm.) Stapf and Hubb.) and veldt grass mainly Urochloa mosambicensis (Hack.) as basal diet (60%). Water was provided individually to all the animals on ad lib. basis. Daily intakes of feed and water were recorded and weighing of the animals was done every two weeks. The collected data were analysed statistically for differences. Average daily weight gain by Tswana sheep was significantly different (p<0.05), sheep fed on millet forage had a higher daily weight gain $(120.24{\pm}8.91g)$ compared with sheep fed on veldt grass $(92.86{\pm}6.94g)$. Treatment effects on daily total DM intake by sheep were significant, the control group (C. ciliaris L.) had higher intake $(705.77{\pm}10.22g)$ and those fed on sorghum forage had the least intake $(668.10{\pm}10.70g)$. There was no significant difference (p>0.05) in the average daily weight gain by Tswana goats and it was 84.52, 73.81, 83.33 and 78.57 g for goats fed on C. ciliaris L., sorghum forage, millet forage and veldt grass respectively. Average daily total DM intake by goats was 655.27, 652.64, 650.07 and 650.94 g for C. ciliaris L., sorghum forage, millet forage and veldt grass respectively. Feed conversion efficiency was 8.00, 8.98, 7.93 and 8.34 for goats fed on C. ciliaris L., sorghum forage, millet forage and veldt grass respectively and were not significantly different (p>0.05).