• Title/Summary/Keyword: Bone maturity

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The Study on Correlations of Risser Sign with the Chronological Age, Bone Age, Menarche, and Adult Height Prediction according to TW3 Method (Risser 증후와 역연령, 골연령, 초경 시기 및 성인 예측신장 (AHP-TW3)과의 관계)

  • Koo, Eun Jin;Lee, Jin Hwa;Kim, Yun Hee
    • The Journal of Pediatrics of Korean Medicine
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    • v.31 no.4
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    • pp.31-38
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    • 2017
  • Objectives The purpose of this study was to find out the clinically reliable relationships between the Risser sign and chronological age, bone age, menarche, and adult height prediction (AHP) and to evidence the reliability of the Risser sign. Methods This study had been carried out with 50 children who had their growth checked in an oriental medical hospital from January 2015 to February 2017. We investigated Risser sign in AP X-rays with iliac crest, bone age, AHP for all 50 children and the timing of menarche from the 22 girls in the study subjects. We also investigated a correlation between the Risser stage and the other indicators to analyze statistical data. Results The mean chronological ages of Risser 1, 2, 3 and 4 were 11.2, 12.6, 14.4, and 15.5 years respectively for the boys and 10.8, 12.2, 13.8 and 14.8 years respectively for the girls. The mean bone ages of Risser 1, 2, 3 and 4 were 12.3, 13.6, 15.7 and 16.5 years respectively for the boys and 11.7, 13.8, 14.3 and 14.9 years respectively for the girls. We analyzed 22 girls' Risser stages in accordance with the duration from menarche. The result showed that in the first six months after menarche, all girls were in Risser 1 and 2; in the next six months, the girls were in Risser 2 on average; in the next 12 months, all girls were in Risser 3 and 4; after more than two years from menarche, all girls were in Risser 4. The mean remaining growth height of Risser 1, 2, 3 and 4 were 27.8, 17.3, 4.4 and 1.0 cm respectively for the boys and 14.5, 5.1, 3.1 and 1.1 cm respectively for the girls. The Risser stage was correlated strongly with chronological age (Spearman's rho=0.707 (boy), 0.841 (girl)), bone age (Spearman's rho=0.869 (boy), 0.875 (girl)), duration from menarche (Spearman's rho=0.909) and remaining growth height (Spearman's rho=-0.784 (boy), -0.878 (girl)). Conclusions This study showed that the Risser sign can be useful in assessing skeletal maturity and predicting remaining growth height based on the Risser stage and the other growth indicators.

Helling Effect of Sintongchugoetang Water Extract on Tibia fractured Rats (가미신통축어탕(加味身痛逐瘀湯)이 흰쥐의 골절유합(骨折癒合)에 미치는 영향(影響))

  • Hang, Tae-Gyung;Oh, Min-suck;Song, Tae-won;Kim, Kil-su
    • Journal of Haehwa Medicine
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    • v.8 no.1
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    • pp.727-738
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    • 1999
  • Sintongchugoetang(CTCOT) is one of the importent prescription that has been used in oriental medicine(yyilimgaechak) for helling fractured condition. The study was done to evaluate effects of CTCOTwater extract on the tibia fractured rats. The result were obtained as follows : 1. In the change of X-ray, experimental group was significantly effected than control. 2. In the changes of body weight, experimental group was decreased than control. 3. In the change of Ca, P and ALP(alkaline phosphatase) on serum, all experimental group was not significant. 4. In the change of bone tissue, experimental group was was significantly effected than control in callus formation and maturity. From above results, CTCOT was had significant effects on the helling of fractured in rats, so it is expected to clinical application.

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Helling Effect of Gamigungguitang and GamigungguitangGaNokyong Water Extract on Tibia fractured Rats (가미궁귀탕(加味芎歸湯) 및 가미궁귀탕가녹용(加味芎歸湯加鹿茸)이 흰쥐의 골절유합(骨折癒合)에 미치는 영향(影響))

  • Ryum, Yik-haon;Oh, Min-suck;Song, tae-won
    • Journal of Haehwa Medicine
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    • v.8 no.1
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    • pp.675-687
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    • 1999
  • Gamigungguitang(GMGGT) and GamigungguitangGaNokyong(GMGGTN) are one of the importent prescription that has been used in oriental medicine(dongyyibangjehak) for helling fractured condition. The study was done to evaluate effects of GMGGT and GMGGTN water extract on the tibia fractured rats. The result were obtained as follows : 1. In the change of X-ray, all experimental group was significantly effected than control. 2. In the changes of body weight, all experimental group was decreased than control. 3. In the change of Ca, P and ALP(alkaline phosphatase) on serum, all experimental group was not significant. 4. In the change of bone tissue, all experimental group was was significantly effected than control in callus formation and maturity. From above results GMGGT and GMGGTNBSH were had significant effects on the helling of fractured in rats, so it is expected to clinical application.

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A Study on the Growth of Low Income and Multicultural Families' Children in Dae-jeon Area (대전 지역 저소득층 및 다문화가정 아동의 성장에 대한 보고)

  • Song, Ji Hyun;Kim, Eun Jin
    • The Journal of Pediatrics of Korean Medicine
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    • v.33 no.1
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    • pp.46-57
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    • 2019
  • Objectives The purpose of this study is to evaluate the growth of low income and multicultural families' children in Dae-jeon area via growth indices, obesity indices and metabolic risk factors. Methods Six to 13-year-old children were enrolled in this study. Children were examined their body composition and bone age and their blood samples were collected. Results Current growth of children in low income and multicultural families was under the average compared to that of average children in the same age. Also, boys were more prone to be overweight than girls and their skeletal maturity was more rapidly progressing. Conclusions Intensive management and more training in regards to exercise and eating habits will be needed to low income and multicultural families' children.

A study of Growth Plate regression analysis using Tanner-Whitehouse 3 in hand AP of pediatrics (소아의 디지털 Hand 영상에서 TW3를 이용한 성장판의 회귀분석)

  • Lee, DongSeong;Jo, GuangSub;Lim, HanSub;Jeong, SeonKyoung;Jang, HwaYoung;Kim, SuHyun;Kang, SeSik;Kim, ChangSoo
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.05a
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    • pp.391-394
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    • 2015
  • They evaluate the bone age using the GP-BP (Greulich-Pyle and Bayley-Pinneau) and TW3 (Tanner-Whitehouse 3) in clinical. The skeletal maturity in Hand AP is evaluated by clinical experience of physicians and this is qualitative evaluation not same in every physicians. In order to devise and evaluate new methods not using TW3 method in this situation. The study was conducted with 70 (Male 35, Female 35) children who visited Yangsan P Hospital from March 2014 to March 2015. The study measured the length of growth plate and distal proximal phalanx and conducted regression analysis for statistical significance test of bone age length difference. The study found average and standard deviation corresponding to certain ranges each bone age. The more bone age increase, the more the length of growth plate and distal proximal phalanx decreased. The girls have less average rather than the boys because bone grows fast. The girls have first period age of 12 to 14, it appears length variation significantly. The study conducted regression analysis and this has statistical significance.

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Diverse and predominantly sub-adult Epinephelus sp. groupers from small-scale fisheries in South Sulawesi, Indonesia

  • Nadiarti Nurdin Kadir;Aidah A. Ala Husain;Dody Priosambodo;Muhammad Jamal;Irmawati;Indrabayu;Abigail Mary Moore
    • Fisheries and Aquatic Sciences
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    • v.26 no.6
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    • pp.380-392
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    • 2023
  • Groupers (Family Epinephelidae) are commonly caught in data-poor small-scale multi-species fisheries for sale on both export and domestic markets. This study presents data on the species composition and size/life-stage structure of Epinephelus spp. groupers caught by small-scale fishers and sold locally in the Indonesian province of South Sulawesi. Data were collected from fishing ports and local markets at 12 sites representing the three seaways around South Sulawesi (Makassar Strait, Flores Sea, Gulf of Bone). Each specimen (n = 3,398) was photographed alongside an object of known length, and total length (TL) was obtained using the Rapid Scaling on Object (RASIO). Of the 23 species identified, four (Epinephelus areolatus, Epinephelus ongus, Epinephelus quoyanus, and Epinephelus fasciatus) collectively comprised 69% of the catch, while the 13 least abundant species contributed less than 5%. The catch was dominated (67%) by the subadult life-stage, with just under 20% in the adult class. Juveniles dominated the catch of Epinephelus fuscoguttatus, a valuable export commodity. Observations of early maturity as well as the sizeable gap between length at first capture (Lc) and length at first maturity (Lm) indicate recruitment overfishing of most species, with the notable exception of Epinephelus rivulatus. The proportion of adult fish was low (≈5%-30%) for the twelve most abundant species (E. areolatus, E. ongus, Epinephelus quoyanus, E. fasciatus, Epinephelus coioides, Epinephelus faveatus, Epinephelus sexfasciatus, Epinephelus maculatus, Epinephelus bleekeri, Epinephelus corallicola, E. fuscoguttatus, Epinephelus polyphekadion). For two moderately abundant species (E. faveatus and E. malabaricus), TL < Lm for all specimens. The limited data available indicate spawning ratio is lower than reported from deep-water fisheries of E. areolatus and E. coioides. The results call for targeted research to fill knowledge gaps regarding the biology and ecology of groupers exploited mainly for domestic markets; highlight the need for species-level data to inform management policies such as minimum legal size regulations; and can contribute towards species-level status assessments.

Association of Angiotensin Converting Enzyme I/D and ${\alpha}$-actinin-3 R577X Genotypes with Growth Factors and Physical Fitness in Korean Children

  • Kim, Kijin;Ahn, Nayoung;Cheun, Wookwang;Hong, Changbae;Byun, Jayoung;Joo, Youngsik
    • The Korean Journal of Physiology and Pharmacology
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    • v.19 no.2
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    • pp.131-139
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    • 2015
  • This study analyzed the differences in aerobic and anaerobic exercise ability and growth-related indicators, depending on the polymorphism of the ACE and the ACTN3 genes, to understand the genetic influence of exercise ability in the growth process of children. The subjects of the study consisted of elementary school students (n=856, age $10.32{\pm}0.07yr$). The anthropometric parameters, physical fitness and growth factors were compared among groups of the ACE I/D or the ACTN3 R577X polymorphisms. There were no significant differences between the anthropometric parameters, physical fitness and growth factors for the ACE gene ID or the ACTN3 gene R577X polymorphism. However, the DD type of ACE gene was highest in the side step test (p<0.05), and the DD type was significantly higher than the II+ID type (p<0.05) in the early bone age. The combined group of the ACE gene II+ID and the ACTN3 gene XX type significantly showed lower early bone age (p< 0.05). This study did not find any individual or compounding effects of the polymorphism in the ACE I/D or the ACTN3 R577X polymorphisms on the anthropometric parameters, physical fitness and growth factors of Korean children. However, the exercise experience and the DD type of the ACE gene may affect the early maturity of the bones.

The growth stage study on the femur and tibia of Korean native chicken after hatching (한국 재래닭의 부화 후 성장단계별 넙다리뼈와 정강뼈 성장에 관한 연구)

  • Tae, Hyun-Jin
    • Korean Journal of Veterinary Service
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    • v.38 no.3
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    • pp.181-188
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    • 2015
  • Skeletal development of chicken has been widely discussed in industrial forums and various research reports. However, these studies were emphasis on the commercial chicken strains for improve egg and meat production whereas the skeletal quiet remains as a potential weak link related to facilitating in the physical support of heavier carcasses at ever younger ages. For that, the study of standardization of skeletal development is important but it was rarely reported in Korean native chicken (KNC). The study was investigated the skeletal characteristics of KNC for international standardization. We studied in KNC at 2, 14, 28, 42, 56, 70, 84, 98, 112, 126, 147, 168, 196, 224, 336 and 448 days after hatch (male and female, n=13 for each group). We measured the body weight (BW), and after sacrifice measured organs and remove muscle from femur & tibia and measured bone weight. Data were analyzed by ANOVA, Duncan test, correlation analysis and regression analysis of SAS 9.1. We analyzed the data of BW, femur & tibia and made growth curve also. The BW was significantly increased up to 147 days after hatch (male, $1,927.88{\pm}68.92g$; female, $1,456.00{\pm}50.11g$), and then increased gradually. At 336 days, these growth was stop (male, $2,467.00{\pm}42.84g$; female, $1,568.71{\pm}62.62g$). The growth of femur & tibia length and width was stop on 98~126 days after hatch. At 98 days, we measured the length and width of femur & tibia in male were $132.39{\pm}3.18mm$ & $25.98{\pm}0.59mm$ whereas in female at 112 days the length of femur & tibia was $116.40{\pm}1.55mm$ and at 126 days width was $21.41{\pm}0.38mm$. Our study suggests that the growth of male KNC was classified pre-puberty (0~98 days), puberty (98~336 days) and maturity (after 336 days), meanwhile female was shown similar trend however puberty period of KNC was 112 or 126 days after hatch.

Radiographic Evaluation of Limb Bone Development in Miniature Porcine (미니돼지의 팔다리 뼈 성장에 대한 방사선학적 평가)

  • Chang, Jin-Hwa;Jung, Joo-Hyun;Choi, Min-Cheol
    • Journal of Life Science
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    • v.17 no.10
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    • pp.1315-1320
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    • 2007
  • Epiphyseal development in the long bones was studied radiographically in minipigs. Radiographs of the proximal and distal epiphyses of humerus, radius, ulna, femur and tibia were obtained at 4, 8, 12, 20, 40, 48, 96 and 144 weeks of age in total 58 minipigs. The assessment of maturity process was made in accordance with the criteria proposed by Owada and Sutow. The secondary ossification centers developed rapidly from 4 weeks of age to 40 weeks of age, and gradually thereafter until 96 weeks of age. The earliest epiphyseal fusion was apparent in the proximal radius, proximal and distal femur at 96 weeks of age. The complete fusion of the epiphyseal line in the long bones was evident on 144 weeks of age and was observed in most long bones such as the proximal humerus, the proximal and distal ulna and the distal radius, and the proximal tibia in minipigs.

Reconstruction of Anterior Cruciate Ligament in Adolescent (청소년기에 시행한 전방십자인대 재건술)

  • Song Eun Kyoo;Shim Sang Don;Kim Hyung Jong;Kim Hyung Won
    • Journal of the Korean Arthroscopy Society
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    • v.6 no.2
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    • pp.101-108
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    • 2002
  • Purpose: To evaluate the clinical results of anterior cruciate ligament (ACL) reconstruction and to know the results of physeal injury by transphyseal tunnel in adolescents who had remaining growth potential. Materials and Methods : This study involved 12 patients under 19 years old out of 445 patients, who underwent ACL reconstruction between 1993 and 2001. The mean age at the time of operation was 15.9 $(13.1\~16.9)$ years and fellow-up period was 45.1 $(24\~120.6)$ months in avrarge. Autologous quadrupled hamstring tendon was used as graft in 11 cases and bone-patellar tendon-bone in 1 case. Clinical results were evaluated by Lysholm Knee Scoring Scale, range of motion and return to preinjury sports activities. Radiologic results were evaluated by $Telos^{\circledR}$ device. Bone maturity were analyzed by chronological age, standing height and the width of growth plate in AP and lateral view of knee joint at preoperatively. The growth disturbances were evaluated by measuring femorotibial angle, anatomical and mechanical lateral distal femoral angle, mechanical medial proximal tibial angle and leg length and by comparing those of uninjured site in last follow-up teleoroentgenogram. Results : The mean Lysholm Knee score was 51 $(25\~63)$points preoperatively and 98 $(94\~100)$ points at last follow up. The mean anterior displacement of the tibia by using $Telos^{\circledR}$ device was improved from 13.5 $(6\~27)$ mm to 2.9 $(1\~4)$ mm and there were no significant instabilities of the knee in all cases. There were no leg length discrepancies over 1 cm and no statistically significant abnormal alignment of the knee joint in all cases. Conclusion: ACL reconstruction using transphyseal tunnel for restoring stability and knee function is assumed as a good mettled of treatment without significant leg length discrepancy and abnormal alignment of the knee joint.

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