• Journal of Nutrition and Health
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• 제33권3호
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• pp.241-249
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• 2000

The bone mineral density(vertebrae Ll-4, femoral neck, Ward's triangle and trochanter) of 160 healthy adult women aged 29-45 was measured and general characteristics, anthropomentric measurements, and dietary intake were also studied to determine the main factors affecting the bone mineral density(BMD) of adult women. The nutrient intake of the subjects was adequate to RDA level except energy, Ca, Fe, and vit A. The BMD of vertebrae L24 showed significant positive association with nutrient intake such as animal protein, P, Ca(animal) and Fe(animal). The BMD of the femoral neck correlated significantly with anthropometric measurements such as height, weight, waist circumference, hip circumference, body fat and body mass index. The BMD of both sites(vertebrae L24 and femoral neck) were significantly related to vertebrae L24 was daily Ca intake and that of femoral neck was daily energy expenditure. In conclusion, adequate nutrient intake, especially protein, P, Ca and Fe as well as increases in physical activity were suggested to prevent the loss of bone mineral density in adult women.

• 동의생리병리학회지
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• 제18권6호
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• pp.1918-1926
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• 2004

Osteoporosis is defined as a progressive systemic skeletal disorder characterized by low bone mineral density, microarchitectual deteriorations of bone and susceptibility to fracture. numerous methods have been used for quantitative assessment of the skeleton in osteoporosis. QCT has been shown to measure changes in trabecular mineral content in the spine with great sensitivity and precision. To provide the normal reference values and changes of lumbar spinal bone mineral density in korean adult spinal bone mineral density was evaluated in 451 women (229 premenopausal and 222 postmenopausal women) and 206 men, aged 20 to 74 years old in Wonkwang hospital from 2000 to 2004, which was carried out by using QCT. women with oophorectomy, vertebral compression fracture, any history of endocrine disease and use of drugs that alter bone metabolism were excluded. According to the WHO definition, a patient is osteoporotic based on a bone mineral density(BMD) measurement that is 2.5 standard deviations (SDs) below typical peak bone mass of young healthy white women. This measurement of standard deviation from peak mass is called the T score. BMD values of normal women in their 20-24 years, 25-29 years, 30-34 years, 35-39 years, 40-44 years, 45-49 years, 50-54 years, 55-59 years, 60-64 years, 65-69 years, over 70 years were 168.95㎎/㏄ K₂PHO₄, 155.41㎎/㏄ K₂PHO₄, 166.87㎎/㏄ K₂PHO₄, 160.67㎎/㏄ K₂PHO₄, 154.06㎎/㏄ K₂PHO₄, 132.04㎎/㏄ K₂PHO₄, 114.05㎎/㏄ K₂PHO₄, 91.78㎎/㏄ K₂PHO₄, 78.61 ㎎/㏄ K₂PHO₄, 61.35㎎/㏄ K₂PHO₄, 50.53㎎/㏄ K₂PHO₄ Mean bone density of normal women was 115.77K₂PHO₄ K₂PHO₄. BMD values of normal men in their 20-24 years, 25-29 years, 30-34 years, 35-39 years, 40-44 years, 45-49 years, 50-54 years, 55-59 years, 60-64 years, 65-69 years, over 70 years were 171.46㎎/㏄ K₂PHO₄, 162.19㎎/㏄ K₂PHO₄, 155.62㎎/㏄ K₂PHO₄, 147.28㎎/㏄ K₂PHO₄, 137.56㎎/㏄ K₂PHO₄, 137.56㎎/㏄ K₂PHO₄, 101.25㎎/㏄ K₂PHO₄, 109.00㎎/㏄ K₂PHO₄, 103.32㎎/㏄ K₂PHO₄, 91.53㎎/㏄ K₂PHO₄, 88.35㎎/㏄ K₂PHO₄ Mean density of normal men was 115.77㎎/㏄ K₂PHO₄. Peak bone density of women and men was in the age group of 20-24 years and 168.95㎎/㏄ K₂PHO₄, 171.46㎎/㏄ K₂PHO₄, respectively. Bone loss was increased with aging and was accelerated in postmenopausal women than that of premenopausal women. The total loss of BMD for women and men was 70.09% and 48.47%, respectively. Postmenopausal women(mean BMD : 85.83㎎/㏄ K₂PHO₄) had significantly lower BMD than premenopausal women(meand BMD : 144.80㎎/㏄ K₂PHO₄)(p<0.001). The annual loss of BMD of women and men was 2.702㎎/㏄ K₂PHO₄ and 1.795㎎/㏄ K₂PHO₄, respectively. This study provided the BMD reference data for normal korean adult. further studies on BMD in healthy adult and comparison with published data are needed.

• The Journal of Korean Physical Therapy
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• 제13권1호
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• pp.97-105
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• 2001

본 연구는 2000년 7월 14일부터 8월 24일까지 대구광역시에 소재한 가톨릭병원 건강검진센타에서 골다공증 검사를 시행한 여성 36명을 대상으로 폐경후 여성의 골밀도차이를 비교하기 위해 실시하였다. 연령의 증가에 따라 요추부의 평균골밀도는 감소되었고, 신장이 증가할수록, 교육수준이 높을수록 평균골밀도는 증가했으며, 독신(이혼, 사별, 별거), 활동적인 직업 , 요통이 없다, 육류의 항목에서 평균골밀도는 각각 증가했지만 유의한 차이는 없었다. 골밀도의 표준편차인 T 값은 -2.5이하의 골다공증군이 41.7%로 가장 많았고, 골밀도 (BMD)는 평균 0.77g/c$m^2$로 나타났다. 가족중 골절시 연령이 증가할수록, 운동횟수, 운동시간이 증가할수록, 분만횟수가 증가할수록, 각각 골밀도는 높게 나타났지만 유의한 차이는 없었다. 자궁 절제술은 안했다가, 혈액형은 A형의 항목에서 골밀도는 높게 나타났지만 유의한 차이는 없었다. 폐경후 골밀도에 영향을 미치는 관련성이 있는 요인은 골밀도의 표준편차인 T 값이다(p<0.05). 본 연구는 폐경후 적성의 골밀도 관련요인에 대한 많은 변수를 고려한 전향적인 연구가 필요할 것으로 사료된다.

• 여성건강간호학회지
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• 제18권3호
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• pp.190-199
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• 2012

Purpose: The purpose of this study was to identify the levels of bone mineral density (BMD) and to explain the factors influencing BMD among female college students in Korea. Methods: A cross-sectional study was conducted with 144 college women. Lifestyle factors were determined by self-report questionnaire. Body composition was measured by body composition analyzer and bone mineral density was measured by ultrasound bone densitometry. Data were analyzed using SPSS for windows, version 19.0. Results: The mean BMD at calcaneus site was 0.56$g/cm^2$ (mean T-score=-0.22). The incidence of osteopenia was 21.5%. Factors predicting BMD were menarche age (r=-.22, p=.009) and height (r=-.18, p=.030) with 7% of explained variance. Conclusion: These results suggest that health care professionals need to provide young women with program that is intended to affect their intention toward osteoporosis preventive behavior change.

• Imaging Science in Dentistry
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• 제33권3호
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• pp.131-135
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• 2003

Purpose: To determine whether the mandibular radiomorphometric indices in panoramic radiography are correlated with the bone mineral density of Cu-equivalent images in intraoral film. Materials and Methods: The bone mineral density (BMD) of the mandibular premolar area was measured in the Cu-equivalent image of intraoral film. The Panoramic Mandibular Index (PMI) and Mandibular Cortical Width (MCW) were measured in panoramic radiographs of six dry mandibles, and the Pearson correlation between PMI, MCW, and BMD were tested. Results: There were no significant correlations between PMI and BMD (r = 0.280), nor between MCW and BMD (r =0.237). Conclusion: The results show that PMI and MCW were poor diagnostic indicators of mandibular BMD in the six dry mandibles used in this study. The correlationship between the mandibular radiomorphometric indices (PMI and MCW) and mandibular BMD needs to be researched further using large in vivo patient samples.

• Journal of Nutrition and Health
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• 제41권2호
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• pp.127-134
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• 2008

The effects of vitamin $D_{3}$ supplementation on bone mineral density and bone mineral content in ovariectmized rats were investigated. Forty female Sprague-Dawley rats (body weight 180 g) were divided into two group, ovariectomy and Sham groups, which were each randomly divided into two subgroups that were fed casein and casein supplemented with vitamin $D_{3}$ diets. Bone mineral density (BMD) and bone mineral content (BMC) were measured using PIXlmus (GE Lunar Co, Wisconsin, USA) in spine and femur on 6 weeks after feeding. Osteocalcin and urinary DPD crosslinks value were measured as markers of bone formation and resorption. The body weight gain and food efficiency ratio (FER) were higher in OVX groups than in Sham groups regardless of diets. Serum Ca concentration and urinary Ca excretion were higher in vitamin $D_{3}$ supplemented group than in casein group in Sham and OVX. Crosslinks values were higher in OVX groups than in Sham groups. Spine BMD and femur BMD of ovariectomy group were significantly lower than Sham groups, however vitamin $D_{3}$ supplemented groups were significantly higher than control groups in Sham and OVX. In conclusion, dietary vitamin $D_{3}$ supplementation on ovariectimized rats were significantly increased bone mineral density and bone mineral content in spine and femur.

• Nutrition Research and Practice
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• 제2권2호
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• pp.68-73
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• 2008

This study was focused on whether or not isoflavones affect the increase in bone mineral density of growing females. Female Sprague-Dawley rats ($60{\pm}5\;g$) were randomly assigned to two groups and provided control diets (control group) or isoflavone-supplemented diet (IF group, 57.8 mg isoflavones/100 g diet) for 9 weeks in growing female rats. Measurements of Bone Mineral Density (BMD) and Bone Mineral Content (BMC) on the experimental animals were executed in the $3^{rd}$, $6^{th}$, $9^{th}$ weeks. In result, there was no significant difference in spine BMD between the isoflavones supplemented group and the control group. But, the IF group tended to have higher BMD than the control group in between 3 and 9 experimental weeks, and the striking difference could be shown in the $6^{th}$ week of feeding. In case of femur BMD, the effects of added isoflavones appeared in the $6^{th}$ week of feeding, and it became intensified in the $9^{th}$ week of feeding to the extent that the BMD in the IF group was significantly higher than that of the control group (p<0.05). In conclusion, isoflavone supplementation increased spine BMD per weight in the $6^{th}$ week of feeding, and affected the increase of femur BMD in the $9^{th}$ week. The result of the experiment implies that it affects positively the formation of spine and femur BMD of growing female rats. The study also suggests that the effects of isoflavone on the pattern of BMD formation might differ from the parts of bones.

• 보건의료산업학회지
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• 제3권2호
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• pp.87-94
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• 2009

The purpose of this study is to evaluate the relationship between osteoporotic postmenopausal women and its bone mineral density value by using the single energy quantitative CT. 1. Decreasing BMD with age is evident. There is a significant low BMD value in the osteoporotic women compared with the healthy subgroup. 2. BMD decrease from T12 to L4, except in healthy premenopausal women. 3. Relationship of spinal BMD expressed as average BMD of T12 through L4 Show strong correlation with mean BMD in all vertebral levels. 4. There are significantly different BMD value from T12 through L4 in subgroup 1, 2, 3 but there is no statistically significant difference between subgroup 2 and 3. Conclusion, There is a significant decreasing BMD with age but it is difficult to differentiate postmenopausal relatively healthy women from osteoporotic women by BMD.

• Journal of Nutrition and Health
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• 제30권3호
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• pp.299-306
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• 1997

Vitamin K takes part in both blood coagulation and bone metabolism via the carboxylation of glutamate residues. This study was performed to examine the relationship between dietary phylloquinone intake and bone mineral denisty(BMD) among postmenopausal Korean women (n=70, age=56). The bone mineral density of the lumbar spine and femoral neck were measured by dual X-ray absorptiometry(DEXA). Daily intakes of phylloquinone and calcium were assessed using a food frequency questionnarie. As a results, body weigh, height and body mass index were not correlated with BMD. However, the number of years since monopause and daily intakes of calcium were significantly correlated with BMD. Although daily intakes of phylloquinone were not correlated with BMD, women with relatively high BMD consumed more phylloquinone than those with lower BMD. The average daily phylloquinone and calcium intakes of the 70 postmenopausal women were 725.8ug/day, ten times more than the American RDA and 406.7mg/day, 1/2 of the American RDA for those nutrients, respectively. The major food sources for phylloquinone were seaweed, spinach and kale, whereas the food sources of calcium were milk, sardines, and yogrut. Further studies are needed to clarify the effects of dietary phyloquinone on its serum levels and BMD.

• Journal of Nutrition and Health
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• 제40권3호
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• pp.235-241
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• 2007

The aim of this study was to define an arginine effect when added to a diet. The influence of arginine supplements on bone mineral density and content were studied in young female Sprague-Dawley rats fed either an arginine supplemented diet or control diet. Twenty four rats (body weight $83{\pm}5g$) were randomly assigned to one of two groups, consuming casein or casein with supplemented arginine diet. All rats were fed on experimental diet and deionized water ad libitum for 9 weeks. Bone mineral density (BMD) and bone mineral content (BMC) were measured using PIXImus (GE Lunar Co, Wisconsin, USA) in spine and femur 3, 6, and 9 weeks after feeding. The serum and urine concentrations of Ca and P were determined. Diet did not affect weight gain and mean food intake. The serum concentration of Ca and P were not changed by arginine supplementation. Urinary Ca excretion was significantly decreased by arginine supplementation. Spine BMD was significantly increased by arginine supplementation on 3 and 6 weeks after feeding. Femur BMD was significantly increased in the group of arginine supplementation on 3, 6, and 9 weeks. Rats fed the arginine-supplemented diet had better bone mineral content than did control diet rats in the experimental period. Therefore, arginine supplementation may be beneficial on spine and femur BMD increment in growing female rats. These are thought to be associated with an arginine-induced growth hormone release. The exact mechanism of this effect remains to be elucidated.