• Safety and Health at Work
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• 제2권2호
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• pp.87-96
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• 2011

In 1967, the problem of occupational lead exposure came to public attention in Korea. Since then, regular progress has been made in lowering workplace lead exposures, instituting new workplace controls, and implementing health examinations of exposed workers. Past serious lead poisoning episodes made it possible to introduce biological monitoring programs on a voluntary basis in high-lead-exposure facilities in Korea. Industry-specific occupational health services for lead workers in Korea during the last 22 years can be categorized into three phases. During the first phase (1988-1993), efforts were directed at increasing awareness among workers about the hazards of lead exposure, biological monitoring of blood zinc protoporphyrin began, and a respiratory protection program was introduced. During the second phase (1994-1997), a computerized health management system for lead workers was developed, blood-lead measurement was added to biologic monitoring, and engineering controls were introduced in the workplace to lower air-lead levels to comply with air-lead regulations. Finally, during the third phase (1998-present), a new biomarker, bone-lead measurement by X-ray fluorescence, was introduced. Bone-lead measurement proved to be useful for assessing body burden and to demonstrate past lead exposure in retired workers. Occupational health service practice for lead workers, including the industry-specific group occupational health system, has brought considerable success in the prevention of lead poisoning and in reducing the lead burden in Korean lead workers during the last several decades. The successful achievement of prevention of lead poisoning in Korea was a result of the combined efforts of lead workers, employers, relevant government agencies, and academic institutes.

• Imaging Science in Dentistry
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• 제50권3호
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• pp.217-226
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• 2020

Purpose: The purpose of this study was to analyze the quantity and quality of the mandibular anterior alveolar bone in terms of alveolar width, density, and total alveolar height (TAH) based on dental status, gender, and age. Additionally, this study aimed to quantitatively evaluate the available alveolar height for graft harvesting (AHGH) and examine its variability based on the aforementioned factors. Materials and Methods: This retrospective cone-beam computed tomographic study included a total of 100 subjects. On the basis of gender, dental status, and age, the scans were divided into 3 primary groups and 8 subgroups. The mandibular alveolar width and density were measured 5 mm mesial to the mental foramen bilaterally and at the midline. The TAH was measured at the midline, and the AHGH was measured as the midline distance between 5 mm apical to the root of the canines and 5 mm superior to the lower border. Results: The mandibular alveolar width was statistically similar between dentulous and edentulous patients (P>0.05). A significantly greater density was observed at the midline in edentulous patients (P<0.05). The TAH was significantly greater in edentulous male patients than in edentulous female patients (P<0.05). Dentulous and male patients had significantly greater AHGH than edentulous and female patients, respectively (P<0.05). Conclusion: Based on the data evaluated in this study, it can be concluded that the mandibular symphyseal area has adequate bone quality and quantity for bone graft harvesting for dental implant therapy.

• 지역사회간호학회지
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• 제16권1호
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• pp.77-85
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• 2005

Purpose: This study was to determine the effects of calcium intake on bone mineral density (BMD) in pre and post menopause women and to provide basic data for enhancing bone health of middle aged women. Methods: A total of 700 middle-aged women living in Seoul and Geonggi Province were interviewed during the period from June 2003 through January 2004 to investigate their social. demographic and physiological characteristics, health and daily activity performance, and their dietary patterns, and bone mineral density was measured. The survey of dietary intake was 24 hour recalls, and the individual calcium intake was calculated using food frequency. Data of 618 subjects was used for the analysis. Of the calcium intake levels, BMD values of the subjects of 20% of high level. 60% of middle level and 20% of low level were analyzed and compared. Results: The level of calcium intake according to general characteristics of the subjects was significantly related to age (p=0.001), education levels (p=.003) and marital status (p=.001). The BMD of the lumbar vertebrae and femur of the subjects taking a high level of calcium showed significantly higher than that of the subjects taking a middle level and low level of calcium. Femoral T-score was also significantly higher in subjects taking a high level of calcium than that of those taking a middle level and lower levels of calcium. Lumber spine T-score was higher in the high level group than that of the middle level group. Conclusion: The study revealed that women taking a high level of calcium had better bone health. Therefore. calcium intake is extremely important in daily dietary intake so that the intake of calcium-rich foods is highly recommended.

• Journal of Periodontal and Implant Science
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• 제53권4호
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• pp.295-305
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• 2023

Purpose: Various methods have been proposed to achieve the nearly complete decontamination of the surface of implants affected by peri-implantitis. We investigated the in vitro debridement efficiency of multiple decontamination methods (Gracey curettes [GC], glycine air-polishing [G-Air], erythritol air-polishing [E-Air] and titanium brushes [TiB]) using a novel spectrophotometric ink-model in 3 different bone defect settings (30°, 60°, and 90°). Methods: Forty-five dental implants were stained with indelible ink and mounted in resin models, which simulated standardised peri-implantitis defects with different bone defect angulations (30°, 60°, and 90°). After each run of instrumentation, the implants were removed from the resin model, and the ink was dissolved in ethanol (97%). A spectrophotometric analysis was performed to detect colour remnants in order to measure the cumulative uncleaned surface area of the implants. Scanning electron microscopy images were taken to assess micromorphological surface changes. Results: Generally, the 60° bone defects were the easiest to debride, and the 30° defects were the most difficult (ink absorption peak: 0.26±0.04 for 60° defects; 0.32±0.06 for 30° defects; 0.27±0.04 for 90° defects). The most effective debridement method was TiB, independently of the bone defect type (TiB vs. GC: P<0.0001; TiB vs. G-Air: P=0.0017; TiB vs. GE-Air: P=0.0007). GE-Air appeared to be the least efficient method for biofilm debridement. Conclusions: T-brushes seem to be a promising decontamination method compared to the other techniques, whereas G-Air was less aggressive on the implant surface. The use of a spectrophotometric model was shown to be a novel but promising assessment method for in vitro ink studies.

• Journal of Preventive Medicine and Public Health
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• 제51권4호
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• pp.217-218
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• 2018

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2015년도 춘계학술대회
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• pp.391-394
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• 2015

임상에서는 GP-BP (Greulich-Pyle and Bayley-Pinneau) 법과 TW3 (Tanner-Whitehouse 3) 법을 사용하여 골연령을 평가하고 있다. Hand AP 영상에서 골성숙도 평가는 전문의의 임상적 경험에 의해 이루어지며 이는 정성적 평가로 모든 전문의마다 동일하게 적용되지 않고 있는 실정이다. 이러한 실정 속에서 TW3 방법이 아닌 새로운 방법을 고안 및 평가하기 위해 2014년 3월부터 2015년 3월까지 양산P병원에서 성장판 검사를 시행한 소아 70명(남 35명, 여 35명)을 대상으로 TW3에서 골성숙 가중치가 가장 높은 7부위를 선정하여 성장판과 골말단 부위의 길이를 측정하여 골연령별 길이의 차이를 측정하였으며 통계적 유의성을 평가하기 위해 회귀분석을 실시하였다. 각 골연령 마다 특정범위에 상응하는 평균과 표준편차 값이 나타났으며, 골연령이 증가할수록 성장판과 뼈 말단부 길이가 규칙성 있게 감소하였다. 여아의 경우 남아에 비해 골성장이 빠르므로, 남아보다 길이 평균값이 전체적으로 작은 값을 가졌다. 이는 12~14세 초경이 나타남에 따라 초경 전후 길이 감소 변화가 크게 나타났기 때문이다. 그 결과 값으로 회귀분석을 하였으며 도출된 값을 분석한 결과 통계적으로 유의함을 알 수 있었다.

• 디지털융복합연구
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• 제12권2호
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• pp.447-453
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• 2014

본 연구는 중년 여성을 대상으로 생활습관에 따라 골밀도와 체력에 미치는 영향을 분석하여 운동프로그램에 관련된 유용한 정보를 제공하는데 목적이 있다. 연구를 수행하기 위하여 C보건소를 내원한 여성 331명을 대상으로 운동습관에 따라 비운동군, 저빈도운동군(주당 2회 이하 운동), 중정도운동군(주당 3회 이상)으로, 음주습관에 따라서는 비음주군과 저음주군(주당 2회 이하 음주), 고음주군(주당 3회 이상), 염분섭취수준에 따라 저염식이군, 중염식이군, 고염식이군으로 각각 분류하였다. 측정변인은 골밀도와 최대산소섭취량, 체지방률, 악력, 유연성, 민첩성, 평형성으로 하였으며, 집단간 차이를 검증하기 위하여 운동습관에 따라서 one-way ANOVA를 각각 실시하였다. 운동습관이 많을수록 골밀도는 유의하게 높았으며, 체지방률은 유의하게 낮게 나타났다. 음주습관과 염분섭취수준에 따른 골밀도 및 체력은 유의한 차이를 보이지 않았지만, 염분섭취가 많을수록 체중과 체지방이 증가하는 경향을 보였다. 결론적으로 규칙적인 운동은 골밀도와 체력유지에 도움을 주며, 고염식이는 체중증가의 요인이 될 수 있을 것으로 사료된다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.3357-3362
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• 2013

The human skeleton is the most common organ to be affected by metastatic cancer and bone metastases are a major cause of cancer morbidity. The five most frequent cancers in Malaysia among males includes prostate whereas breast cancer is among those in females, both being associated with skeletal lesions. Bone metastases weaken bone structure, causing a range of symptoms and complications thus developing skeletal-related events (SRE). Patients with SRE may require palliative radiotherapy or surgery to bone for pain, having hypercalcaemia, pathologic fractures, and spinal cord compression. These complications contribute to a decline in patient healthrelated quality of life. The multidimensional assessment of health-related quality of life for those patients is important other than considering a beneficial treatment impact on patient survival, since the side effects of treatment and disease symptoms can significantly impact health-related quality of life. Cancer treatment could contribute to significant financial implications for the healthcare system. Therefore, it is essential to assess the health-related quality of life and treatment cost, among prostate and breast cancer patients in countries like Malaysia to rationalized cost-effective way for budget allocation or utilization of health care resources, hence helping in providing more personalized treatment for cancer patients.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 1999년도 Japanese Journal of Medical Physics
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• pp.360-363
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• 1999

• BMB Reports
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• 제43권8호
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• pp.513-523
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• 2010

Cytokines that bind to and signal through the gp130 co-receptor subunit include interleukin (IL)-6, IL-11, oncostatin M (OSM), leukemia inhibitory factor (LIF), cardiotrophin-1 (CT-1), and ciliary neutrophic factor (CNTF). Apart from contributing to inflammation, gp130 signalling cytokines also function in the maintenance of bone homeostasis. Expression of each of these cytokines and their ligand-specific receptors is observed in bone and joint cells, and bone-active hormones and inflammatory cytokines regulate their expression. gp130 signalling cytokines have been shown to regulate the differentiation and activity of osteoblasts, osteoclasts and chondrocytes. Furthermore, cytokine and receptor specific gene-knockout mouse models have identified distinct roles for each of these cytokines in regulating bone resorption, bone formation and bone growth. This review will discuss the current models of paracrine and endocrine actions of gp130-signalling cytokines in bone remodelling and growth, as well as their impact in pathologic bone remodelling evident in periodontal disease, rheumatoid arthritis, spondylarthropathies and osteoarthritis.