• 한국균학회지
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• 제13권4호
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• pp.249-262
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• 1985

1983년(年) 7월(月)부터 84년(年) 10월(月)까지 지리산(地異山), 속리산(俗離山), 덕유산(德裕山), 칠갑산(七甲山), 계룡산(鷄龍山) 지역(地域) 및 충남일원(忠南一圓)에서 젖버섯 속(屬)에 속하는 균류(菌類)들을 채집(探集)하여 분류(分類)한 결과(結果) Lactarius 19종, 4변종 및 1 form이 동정(同定)되었다. 이들 Lactarius를 Hesler 및 Smith(1979)의 체계(體係)에 따라 6 section으로 나누었으며 이중 한국(韓國)에서 처음 발견된 버섯은 다음과 같다. L. lignyotus var. nigroviolascens (Atk.) Hesler & Smith 보라잿빛 헛대 젖버섯, L. sumstinei Pk. 우산주름 젖버섯, L. subvellereus var. subdistans Hesler & Smith 노란주름융단 젖버섯, L. vellereus var. virescens Hesler & Smith 푸른주름융단 젖버섯, L. piperatus var. glaucescens (Crossl.) Hesler & Smith 녹색젖 굴털이, L. luteolus Pk. 갈색끈적 젖버섯, L. pyrogalus (Fr.) Fr. 제브라 젖버섯, L. argillaceifolius var. argillaceifolius Hesler & Smith 흑갈색주름 젖버섯, L. repraesentaneus Britz. 보라빛주름 젖버섯, L. mutabilis Pk. 진갈색무늬 젖버섯, L. thejogalus (Fr.) S.F. Gray 갈황색 젖버섯, L. gracilis Hongo 애기 털 젖버섯, L. cyathula f. japonicus Hongo 애기낙엽 젖버섯.

• 한국축산식품학회지
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• 제26권4호
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• pp.511-516
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• 2006

발효 소시지의 제조에 starter로 사용한 균주를 선발하기 위해 각 유산균 균주들의 ACE 저해 활성, 콜레스테롤 흡착능력, 발효 육제품 저장 중 S. aureus에 대한 저해 황성을 평가하였다. ACE 저해 활성은 L. plantarum L167이 가장 우수하였고(58.75%), 콜레스테롤 흡착 능력이 우수한 균주로는 L. plantarum L155를 선발하였다. 박테리오신을 생산하는 P. damnosus를 starter로 이용하여 제조한 발효 소시지에 S. aureus를 접종하여 상온 저장 중 생균수를 측정한 결과 저장 35일째에 대조구에 비하여 1 log의 균수 감소 효과가 나타났다.

• Biotechnology and Bioprocess Engineering:BBE
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• 제9권3호
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• pp.171-178
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• 2004

Glucose alone was found to be the most effective carbon source for producing compactin. An initial glucose concentration of 40 g/L gave the highest compactin concentration of 250mg/L. Among the various nitrogen sources, when 5g/L of pharmamedia and soybean meal as the sole nitrogen source were used, respectively, the compactin concentration was higher than 250mg/L. Especially, in the case of the mixture of 6 g/L of pharmamedia and 8 g/L of soybean meal, the compactin concentration was 400mg/L. To select the best surfactant for effective compactin production, various surfactants were investigated. When Triton X-100 was used, the maximum compactin concentration was 445mg/L. With the initial concentration ranging from 1.5 to 2.0 g/L, the compactin concentration was the highest at 465-450mg/L. The cell concentration was similar to that of the control without the addition of Triton X-100. On the other hand, when the above 4.0 g/L of Triton X-100 were used, the cell concentration decreased. Using the based results, the continuous fed-batch cultures by adding the Triton X-100 were carried out for 10 days in an air-lift bioreactor. When 1.5 g/L of Triton X-100 was added to the culture broth at 0, 4, and 8 days of culture, respectively, the compactin production was increased with the increase of culture time. The maximum compactin concentration after 10days of culture was 1,200mg/L, which was about 2.0-fold higher than that of the control without the addition of Triton X-100.

• Food Science and Biotechnology
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• 제17권2호
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• pp.362-366
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• 2008

Anti-lipogenic effects of tannic acid on 3T3-L1 adipocytes as well as on rats fed high fat diet (HFD) were investigated. Tannic acid stimulated lipolysis through suppression of the leptin secretion and an increase of glycerol release in a dose dependent manner in 3T3-L1 adipocytes. For animal study, the rats were fed either HFD or HFD supplemented with 1%(w/w) tannic acid (HFDT) for 12 weeks, respectively. Body weight gain, liver weight, and visceral fat mass in rats fed HFDT were significantly decreased compared to those of rats fed HFD. The lipid profiles of HFDT group were significantly decreased compared with HFD group in the serum and liver, whereas fecal total cholesterol excretion was increased in HFDT group. These results suggest that anti-lipogenic effect of tannic acid in 3T3-L1 adipocytes and in rats fed HFD may be due to the stimulation of lipolysis and the reduction of lipid levels.

• 대한의생명과학회지
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• 제18권3호
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• pp.291-298
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• 2012

The antiobesity effect of the mixture of black garlic and Garsinia cambogia extracts (BGG) was investigated by measuring the Oil red O staining and the expressions of adipogenic genes during preadipocyte differentiation by real-time PCR in the 3T3-L1 adipocytes. BGG reduced contents of Oil red O dye in the 3T3-L1 adipocytes. mRNA expression levels of SREBP1c, C/EBPa, aP2/FABP4, and $PPAR{\gamma}$ which are adipogenic transcription factor, in cells treated with BGG were also significantly down regulated. Also, the phosphorylation of AMP-activated protein kinase (AMPK) in L6 cells was more increased by BGG. These results indicate that BGG seems to be more attractive compound for application of industry than individual extracts such as black garlic and Garsinia cambogia, considering it has two effects not only inhibit the preadipocyte differentiation but also activate the phosphorylation of AMPK unlike other two compound.

• The Korean Journal of Physiology and Pharmacology
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• 제7권4호
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• pp.247-250
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• 2003

A simple and sensitive assay method was developed for cefepime in human plasma using high performance liquid chromatography (HPLC). Cefepime and cefadroxil (the internal standard) were extracted from heparinized human plasma by simple deproteination with perchloric acid. The extract was injected into an Atlantis dC18 column ($250{\times}4.6$ mm; particle size $5{\mu}m$, Waters) and the column was eluted with methanol and 0.01 M dihydrogen phosphate at pH 3.0 (15：85 v：v) as a mobile phase at a flow rate of 0.7 mL/min. Linearity was confirmed for the range 0.25 to $200{\mu}L/mL$ and the limit of quantitation was $0.25{\mu}L/mL$. The retention times were 10.2 min and 13.4 min for cefepime and cefadroxil, respectively. This method was successfully applied to a pharmacokinetic study of cefepime in plasma from bone marrow transplant patients.

• The Korean Journal of Ecology
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• 제6권4호
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• pp.243-249
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• 1983

Absorption pattern of potassium, calcium, phosphate and nitrate ions, and the pH change during ion-absorption at pH 3.0-11.0 by Oryza sativa L. were studied to investigate indirectly the evidence of H^+-efflux by ATPase. The rice seedlings which were grown either in $L^{\circ} -dark or in L^+-sunlight$, were used both in each ion-absorption to compare with one another. The uptake rate of these ions appeared to favor more in $L^+than in L^{\circ}$, over all range in pH, nearly with the same pattern. The absorption of potassium resulted in bell shape and that of calcium increased linearly to the alkali range. The shape of phosphate-absorption showed nearly the t-distribution curve with high value in acid range and the uptake of nitrate resulted in the dual peaks, but higher in acid range. The pH of the external solution changed from the range of 3.5-11.0 to 3.5-7.0 after lhr-absorptioin, and further acidified after 3hr-absorption. It is suggested that the pH change of the external solution be affected by $ H^+-efflux$ which may be caused by the ATP-hydrolysis.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2008년도 춘계 학술발표회 초청강연 및 논문집
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• pp.366-376
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• 2008

The model tests of short pile with very small pile length/diameter(L/D) were performed in this paper. Varying the pile diameter, length, and the lateral loading point, the lateral resistance and behavior of very short pile were studied in this model tests. The experimental and analytical results are as follows. The lateral ultimate resistance of short pile in sands was the maximum at the point of h/L=0.75, regardless of pile length/diameter(L/D). As the pile diameter is larger, the lateral ultimate resistance of pile with L/D=1 decreases a little and the lateral resistance increases according to the ratio of pile length/diameter. As the lateral loads are acting on the pile, the displacement of pile head is maximum at the pile top of h/L=0, but minimum at the middle point of the pile. And if the loading point is under the middle of pile, the displacement of pile head occurs oposite in the loading direction, but its magnitude is very small.

• 대한기계학회논문집A
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• 제28권4호
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• pp.333-342
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• 2004

Tensile and low cycle fatigue (LCF) tests on prior cold worked 316L stainless steel were carried out at various temperatures from room temperature to 650$^{\circ}C$. At all test temperatures, cold worked material showed the tendency of higher strength and lower ductility compared with those of solution treated material. The embrittlement of material occurred in the temperature region from 300$^{\circ}C$ to 600$^{\circ}C$ due to dynamic strain aging. Following initial cyclic hardening for a few cycles, cycling softening was observed to dominate until failure occurred during LCF deformation, and the cyclic softening behavior strongly depended on temperature and strain amplitude. Non-Masing behavior was observed at all test temperatures and hysteresis energy curve method was employed to describe the stress-strain hysteresis loops at half$.$life. The prediction shows a good agreement with the experimental results.

• 한국컴퓨터정보학회논문지
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• 제21권9호
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• pp.1-9
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• 2016

Recent embedded processors employ set-associative L1 instruction cache to improve the performance. The energy consumption in the set-associative L1 instruction cache accounts for considerable portion in the embedded processor. When an instruction is required from the processor, all ways in the set-associative instruction cache are accessed in parallel. In this paper, we propose the technique to reduce the energy consumption in the set-associative L1 instruction cache effectively by accessing only one way. Gshare branch predictor is employed to predict the instruction flow and determine the way to fetch the instruction. When the branch prediction is untaken, next instruction in a sequential order can be fetched from the instruction cache by accessing only one way. According to our simulations with SPEC2006 benchmarks, the proposed technique requires negligible hardware overhead and shows 20% energy reduction on average in 4-way L1 instruction cache.