• Journal of the Korea Institute of Building Construction
• /
• v.16 no.5
• /
• pp.397-403
• /
• 2016

As a building energy saving standard strengthened, The number of building installed external thermal insulation composite system(ETICS) using EPS insulation increased. But frequent fire accident in the buildings installed EIFS using EPS led to strengthening of building fire safety regulation. This study is for fire property of EPS ETICS reinforced with noncombustible calcium silicate-based mineral insulation as a fire spread prevention structure(FSPS). Fire test for large scale wall by ISO 13785-2 was applied and results showed EPS EIFS with FSPS got 3~8 times superior fire safety than normal EIFS by visual investigation. Temperature and heat flux measurement results, which data of upside of specimen were lower than downside, also supported fire safety of EIFS with FSPS.

• Journal of Sasang Constitutional Medicine
• /
• v.21 no.1
• /
• pp.139-149
• /
• 2009

1. Objectives The roots of Sophora flavescens Aiton (SFA) are widely used as a herbal remedy for allergic inflammation. In this study, we invested the effect of SFA on passive cutaneous anaphylaxis reaction and histamin releas and we demonstrated that SFA suppressed the production of pro-inflammatory cytokines, such as tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin- 6 (IL-6), and interleukin -8 (IL-8), through inhibition of the $NF{\kappa}B$, JNK and p38 pathway in the human mast cell line, HMC-1. 2. Methods To accomplish this, we invested passive cutaneous anaphylaxis reaction and histamin release at an animal experiment. In addition, we investigated the effect of SFA on the production of inflammation-related cytokines in HMC-1 cells that were co-treated with PMA and A23187, which can induce production of pro-inflammatory cytokines. 3. Results and Conclusions SFA induced passive cutaneous anaphylaxis reaction and histamin releas and supressed the expression of TNF-${\alpha}$, IL-6, and IL-8. In addition, the protein levels of TNF-${\alpha}$ were also decreased by SFA treatment. Furthermore, SFA inhibited the nuclear translocation of nuclear factor $NF{\kappa}B$ through inhibition of the phosphorylation and degradation of $I{\kappa}B-{\alpha}$, which is an inhibitor of $NF{\kappa}B$. Moreover, SFA also inhibited induction of MAPKs (JNK, p38) and $NF{\kappa}B$ promoter-mediated luciferase activity. Taken together, these results suggest that SFA could be used as a treatment for mast cell-derived allergic inflammatory diseases.

• Proceedings of the KIEE Conference
• /
• 1994.07b
• /
• pp.1517-1519
• /
• 1994

This paper describes electrical environmental study of a 765kV double circuit test line. Corona performance on several candidate conductor bundles has been investigated in the corona cage (single phase simulation facility) since 1984. We have known that six RAIL conductor bundle is the most suitable for the 765kV transmission Line, [3] To investigate electrical environmental impact of the future commerciale line, we build a full sacle 765kV test line in 1993. The test results of Audible Noise, Radio Interference, TV Interference from August, 1993 to Jan. 1994 were measured as $48.7[dBA](L_{50})$. $57.4[dB{\mu}V/m]$(Fair weather, $L_{50})$. $14.5[dB${\mu}$V/m]$(Fair weather, $L_{50}$). We have found that the Audible Noise data were very close to the predicted(48.5 [dBA]) by BPA Corona and Field Effects Computer program, however, the RI and TVI data were much higher than predicted(42 [dBmV/m], $7.9[dB{\mu}V/m)$ by the BPA program. We have investigating the reason of the difference. In the constructing of full scale test line, we developed the tubular tower, 765kV test transformer and hardwares of 765kV transmission line insulator strings. Also we will investigate the effects of plants under the 765kV test Line.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.21 no.3
• /
• pp.709-713
• /
• 2007

Basement membranes (BMs) are extracellular matrices associated with epithelia, endothelia, muscle, fat and peripheral nerve. They are involved in cell survival, migration, differentiation. BMs functions also include tissue formation and provide mechanical stability as a selective barriers. Laminins are heterotrimeric glycoproteins found in BMs and have a crucial role in cell adhesion and signalling. Madin-Darby canine kidney (MDCK) cells are the best established mammalian model for studying epithelial cell biology The cells form an epithelial monolayer, with tight junctions separating an apical surface from a basolateral membrane facing the filter support and neighboring cells. In this study, using MDCK cells, the synthesis of the BM protein such as laminin with or without methanol extract of Chrysanthemum morifolium (CM) stimulation was analyzed by immunoblotting and CM showed significant increased cell density and enhanced synthesis of laminin.

• Journal of the Korean Society of School Health
• /
• v.20 no.1
• /
• pp.63-75
• /
• 2007

Purpose: With economic development and prolonged longevity, the level of health and health disparities have became growing concerns for individual and society as well. Since youth's health status are influenced by households' socioeconomic status and associated with heath status in later stage of life, assessing health inequality in the youth is a significant step toward lessening health disparity and promoting health. We measured health inequality in high school students and decomposed it into health factors. Methods: The subjects included 3,787 high school students of 12th graders from the Korea Education and Employment Panel (KEEP) in 2004. True health status was assumed as a latent variable and estimated by ordered logistic regression model. The predicted health was used as a measure of individual health after rPSraling to [0,1] interval. Total health inequality was then measured by Gini coefficient and was decomposed into health factors. Results: Health inequality in high school students was observed. Of total health inequality, 44% was explained by biological factors such as body mass index (BMI) (32.5%) and gender (13.5%). Behavioral factors such as smoking, drinking, physical activity, hours in bed and hours of computer ussge added to 11.7%. Household income and work experiences explained 5.6% and 8.8%, respectively. School satisfaction explained 14.6%. Other school related factors such as self-assessed achievement and experience of being bullied accounted for 15.5%. Conclusion: Among the health factors, biological factor was the most important contributor in health disparity. Other factors such as health behaviors, socioeconomic factors, school satisfaction and school related factors exhibited somewhat similar magnitude. For policy purposes, it is recommended to look into modifiable factors depending BM, gender and school surroundings.

• Journal of the Institute of Electronics Engineers of Korea SD
• /
• v.46 no.9
• /
• pp.58-67
• /
• 2009

This paper presents a fully digital gain control system with a new high bandwidth and wide dynamic range power detector for DVB-S2 application. Because the peak-to-average power ratio (PAPR) of DVB-S2 system is so high and the settling time requirement is so stringent, the conventional closed-loop analog gain control scheme cannot be used. The digital gain control is necessary for the robust gain control and the direct digital interface with the baseband modem. Also, it has several advantages over the analog gain control in terms of the settling time and insensitivity to the process, voltage and temperature variation. In order to have a wide gain range with fine step resolution, a new AGC system is proposed. The system is composed of high-bandwidth digital VGAs, wide dynamic range power detectors with RMS detector, low power SAR type ADC, and a digital gain controller. To reduce the power consumption and chip area, only one SAR type ADC is used, and its input is time-interleaved based on four power detectors. Simulation and measurement results show that the new AGC system converges with gain error less than 0.25 dB to the desired level within $10{\mu}s$. It is implemented in a $0.18{\mu}m$ CMOS process. The measurement results of the proposed IF AGC system exhibit 80-dB gain range with 0.25-dB resolution, 8 nV/$\sqrt{Hz}$ input referred noise, and 5-dBm $IIP_3$ at 60-mW power consumption. The power detector shows the 35dB dynamic range for 100 MHz input.

• Journal of the Korean Society of Marine Environment & Safety
• /
• v.23 no.1
• /
• pp.91-97
• /
• 2017

This study contains research on a bio-monitoring system (BMS) capable of detecting abnormal high water temperatures, the shell valve movements (SVMs) of Pacific oysters (Crassostrea gigas), which were measured at four different temperature (5, 10, 20 and $30^{\circ}C$) under laboratory conditions. All the Pacific oysters were kept under fasting conditions for 3 days to prevent the influence of food and excretions before the onset of the experiments. SVMs did not detect at $5^{\circ}C$. However, SVMs increased with an increase in temperature (at $10^{\circ}C$ : $6.31{\pm}2.18times/hr$ and at $20^{\circ}C$: $22.0{\pm}10.0times/hr$). At $30^{\circ}C$, SVMs were divided into two groups: those with no SVMs as at $5^{\circ}C$ and those with SVMs similar to conditions at $20^{\circ}C$($23.9{\pm}9.35times/hr$). This indicates oyster shells maintain a closed condition due to a decrease in metabolism at $30^{\circ}C$, although some Pacific oysters had active SVMs due to an increase in metabolism. If a BMS using the SVM status of Pacific oysters was installed to monitor abnormal high water around oyster farms, early warning levels and serious alerts might be made available more rapidly for SVMs of more than ca. 30 times/hr and closing conditions in a matter of hours, respectively. Therefore, a BMS using the SVMs of Pacific oysters might be an effective early warning system for abnormal high water temperatures.

• Journal of the Institute of Electronics Engineers of Korea SD
• /
• v.44 no.9
• /
• pp.25-33
• /
• 2007

In this paper, the high isolation and wideband 94 GHz MIMIC(Millimeter-wave Monolithic Integrated Circuit) single balanced cascode mixer was designed and fabricated. Also, we designed and fabricated a 3 dB tandem coupler which has a high isolation and wideband characteristic. The single balanced resistive mixer which does not require an external IF balun was designed using the 0.1 ${\mu}m$ InGaAs/InAlAs/GaAs metamorphic HEMT(High Electron Mobility Transistor). The DC characteristics of MHEMT's are 665 mA/mm of drain current density, 691 mS/mm of maximum transconductance. The current gain cut-off frequency($f_T$) is 189 GHz and the maximum oscillation frequency($f_{max}$) is 334 GHz. A 94 GHz single balanced cascode mixer was fabricated using our 0.1 ${\mu}m$ MHEMT MIMIC process. From the measurements, the fabricated couplers showed wideband characteristics. The conversion loss of single balanced cascode mixer was 9.8 dB at an LO power of 10.9 dBm. The LO to RF isolation of single balanced cascode mixer was 29.5 dB at 94 GHz. We obtained in this study a higher LO-RF isolation compared to some other single balanced mixers.

• Journal of Sericultural and Entomological Science
• /
• v.53 no.1
• /
• pp.55-60
• /
• 2015

Melittin is the main component of Bee Venom and has antibacterial activity against several bacteria. To produce the melittin antimicrobial peptide, we constructed transgenic silkworm that expressed melittin gene under the control BmA3 promoter using piggyBac vector. The use of the 3xP3-driven EGFP cDNA as a marker allowed us to rapidly distinguish transgenic silkworm. Mixtures of the donor vector and helper vector were micro-injected into 300 eggs of bivoltin silkworms, Baegokjam. In total, 131 larvae (G0) were hatched and allowed to develop into moths. The resulting G1 generation consisted of 36 broods, and we selected 4 broods containing at least 1 EGFP-positive embryo. The rate of successful transgenesis for the G1 broods was 11%. We identified 12 EGFP-positive G1 moths and these were backcrossed with wild-type moths. With the aim of identifying a melittin as antimicrobial peptide, we investigated the Radical diffusion Assay (RDA) and then demonstrated that melittin possesses high antibacterial activities against gramnegative bacteria.

• Journal of Welding and Joining
• /
• v.27 no.2
• /
• pp.69-75
• /
• 2009

The effects of welding speed were investigated on penetration characteristics, defects and mechanical properties including formability test in Nd:YAG laser welded 1000MPa grade DP steels. A shielding gas was not used and bead-on-plate welding was performed with various welding speeds at 3.5kW laser power. Defects of surface and inner beads were not observed in all welding speeds. As the welding speed increased, the weld cross-section varied from the trapezoid having wider bottom bead, through X type, finally to V type in partial penetration range of welding speeds. The characteristic of hardness distribution was also investigated. The center of HAZ had maximum hardness, followed by a slight decrease of hardness as approaching to FZ. Significant softening occurred at the HAZ near BM. Regardless of the welding speed, the weld showed approximately the same hardness distribution. In the perpendicular tensile test with respect to the weld direction, all specimens were fractured at the softening zone. In the parallel tensile test to the weld direction, the first crack occurred at weld center and then propagated into the weld. Good formability over 80% was taken for all welding conditions.