• Title/Summary/Keyword: Blood component

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Effect of Oxygen Concentration, Physical Trauma on Proliferation of Umbilical Cord Blood-derived Mesenchymal Stem Cells (산소 농도의 변화와 물리적 손상이 제대혈 중간엽 줄기세포의 증식에 미치는 영향)

  • Park, Ran-Sook
    • The Korean Journal of Food And Nutrition
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    • v.24 no.4
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    • pp.803-807
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    • 2011
  • Human umbilical Mesenchymal Stem Cell(uMSC) has been known as one of major component to regenerate connective tissues such as bone, cartilage, fat and others. The effect of low(5%), normotensive(20%) oxygen and freezing-thawing damage on proliferation of uMSC were investigated. low oxygen concentration culture of uMSC resulted in enhanced proliferation significantly($p$ <0.05) than 20% of oxygen culture. After the freezing-thawing injury to uMSC, 5% oxygen culture showed marked proliferation of uMSC than that of 20% oxygen($p$ <0.05) in the 5th passage of uMSC. Expression of antioxidant enzymes such as superoxide anion 1 and glutathione peroxidase 1 appeared marked in 20% oxygen cultured uMSC, which suggest oxidative stress could induce less proliferation of uMSC. Above findings would suggest proliferation of uMSC in 5% of oxygen will give more yields.

A literature Study on 竹瀝 (A study for Aquacupunture Experiment of SUCCUS PHYLLOSTACHYOS) (죽력(竹瀝)의 문헌적(文獻的) 고찰(考察)(죽력(竹瀝)의 약침실험(藥鍼實驗)을 위한 문헌적(文獻的) 고찰(考察)))

  • Park, Kyung-Jin;Chae, Woo-Suk
    • Journal of Acupuncture Research
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    • v.18 no.3
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    • pp.184-200
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    • 2001
  • Objective : To research SUCCUS PHYLLOSTACHYOS through 38 kinds texts over generation for acuacupunture experiment of SUCCUS PHYLLOSTACHYOS. Methods : I studied origin, alias, species, tastes, meridian, effect, treatment, component, medical action and contraindication of SUCCUS PHYLLOSTACHYOS through 38 kinds mecical literatures. Results : Medical actions of SUCCUS PHYLLOSTACHYOS are Resolving slippery phlegm, Reducing fever, Nourishing Yin, Expelling wind and Activating blood circulation. Therefore SUCCUS PHYLLOSTACHYOS can be applied to aphonia, wind arthralgia, Diabetes, epilepsy and convulsive seizure in children. Specially for phlegm-retention due to stroke, it must be used with fresh ginger juice.

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Analysis and role of oligosaccharides in milk

  • Ruhaak, L. Renee;Lebrilla, Carlito B.
    • BMB Reports
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    • v.45 no.8
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    • pp.442-451
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    • 2012
  • Milk is an important fluid in glycobiology because it contains a number of short carbohydrate chains either free or as glycoconjugates. These compounds as a class are the most abundant component and benefit the infant by developing and maintaining the infant's gut flora. New and emerging methods for oligosaccharide analysis have been developed to study milk. These methods allow for the rapid profiling of oligosaccharide mixtures with quantitation. With these tools, the role of oligosaccharide in milk is being understood. They further point to how oligosaccharide analysis can be performed, which until now has been very difficult and have lagged significantly those of other biopolymers.

THERMAL EFFECTS OF EYELID IN HUMAN EYE TEMPERATURE MODEL

  • Gokul, K.C.;Gurung, D.B.;Adhikary, P.R.
    • Journal of applied mathematics & informatics
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    • v.32 no.5_6
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    • pp.649-663
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    • 2014
  • Presence of eyelid on anterior ocular surface and its thermal effects play significant role in maintaining eye temperature. In most of the literatures of thermal modeling in human eye, the eyelid is not considered as an eye component. In this paper, finite element model is developed to investigate the thermal effects of eyelid closure and opening in human eye. Based on different properties and parameter values reported in literatures, the bio-heat transfer process is simulated and compared with experimental results in steady and transient state cases. The sensitivity analysis using various ambient temperatures, evaporation rates, blood temperatures and lens thermal conductivities is carried out. The temperature values so obtained in open eye show a good agreement with past results. The closure of eyelid is found to increase/decrease the eye temperature significantly than its opening, when the parameter values are considered to be at extreme.

Literatual Study on Cause and Treatment of Amnesia (건망(健忘)의 병인(病因) 치료(治療)에 관(關)한 문헌고찰(文獻考察))

  • Joo Seung-Gyun;Goo Byung-Soo;Kim Sung-Wook
    • Journal of Oriental Neuropsychiatry
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    • v.12 no.2
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    • pp.69-84
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    • 2001
  • Objectives : We suggest the method of oriental neuropsychiatry treatment about amnesia through herb therapy. Methods : We investigate cause of disease, component of herbs about amnesia with classic current oriental medicine books. Results : Amnesia is due to simsinbulgyo(心腎不交), biwieyangher(脾胃陽虛), dammisimgyoo(痰迷心竅), emotional damage(七情所傷), extravasated blood(瘀血), deficiency of kidney (腎虛). There is 138 kind of herbs are used in our study that we find out that most frequently used herb is ginseng(人蔘). Heart meridian is the highest use in the all meridians. Sungon(性溫) is the highest use in the all kimi(氣味) Conclusions : We could confirm that herbs of amnesia treatment was related to the three vital organs(臟) named of spleen(脾), lung(肺), kidney(腎).

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General Pharmacology of $\imath$--Muscone ($\imath$-Muscone의 일반약리작용)

  • 이선미;조태순;심상호;박석기;홍채영;김성수;신대희;김용기;박대규
    • Biomolecules & Therapeutics
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    • v.5 no.3
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    • pp.292-298
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    • 1997
  • General pharmacological properties of ι-muscone, the major component of musk, were investigatedin mice, rats and guinea pig. The administration of ι-muscone (1, 10, 100 mg/kg, p.o.) in mice had no effects in general behaviors, and no influences on analgesic actions and normal body temperature. Muscle relaxant action, intestinal propulsion and gastric secretion were not observed even at the high dose of 100 mg/kg. ι-Muscone (1, 10, 100 mg/kg, p.o.) given to conscious rats showed no effect on mean blood pressure and heart rate. It showed no direct effect at 2.4$\times$10.3 mg/ml and 2.4$\times$10-2 mg/ml in isolated uterus of rats and ileum of guinea pig, and also had no inhibition of contraction induced by oxytocin and histamine.

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Antithrombogenicity of the Surfacfe of Poly(r-benzyl L-glutamate)/ Poly(ethylene glycol) Block Copolymer (Poly(r-benzyl L-glutamate)/ poly(ethylene glycol) block 공중합체 표면의 항혈전성에 관한 연구)

  • 조종수;송수창
    • Journal of Biomedical Engineering Research
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    • v.8 no.2
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    • pp.199-204
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    • 1987
  • ABA type block copolymers composed of r benzyle L-glutamate as the A component and poly(ethylene glycol) as the B components were obtained. Platelet adhesion on their sunfaces was investigated by a column elusion method to examine the effects of microdomain and secondary structure. The number of platelets adhered from whole blood and plasma rich platelet was smaller for the block copolymer systems than for the homopolymers. In the block copolymer system, the number of platelets adrered on their surfaces increased with increasing the content of PEG, that is, with decreasing of a-helix of block copolymers. A thick thrombus formation on the PBLG homopolymer was observed than block copolymer by scanning electron micrographs. The platelets adhesion increased with increasing the critical surface tension of the block copolymer.

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Novel Flow Suppression Technique in MRI (핵자기 공명 영상에서 새로운 유속 흐름제거 방법)

  • Ro, Y.M.;Cho, Z.H.
    • Proceedings of the KOSOMBE Conference
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    • v.1992 no.05
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    • pp.92-97
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    • 1992
  • The pulsatile nature of blood flow makes artefacts in 2D Fourier transform image. Spatial presaturation is known to be effective in eliminating flow artefacts when the spin echo acquisition is employed. However. this method requires additional RF pulse and spoiling gradient for presaturation. In this paper a new flow saturation technique which does not require additional saturation-RF and gradient is proposed. The proposed technique is equivalent to the existing saturation technique but the elimination of the flow component is achieved by a pair of tailored $90^{\circ}-180^{\circ}$ RF pulses in tile spin echo sequence. By use of two tailored RF pulses with opposite phase polarity, a linear phase gradient is generated for those moving materials and consequently all the spins of moving materials become dephased thereby no signal is observable. Computer simulations and experimental results obtained using both a phantom and a human volunteer with a 2.0 T whole body system are also presented.

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A Study on the Pulse Doppler System with M-mode Image and Spectrum Analyzer (주파수 해석기와 M-mode 영상을 갖는 펄스 도플러 장치의 개발에 관한 연구)

  • Jeong, Taek-Seob;Park, Sei-Hyun;Kim, Young-Kil
    • Proceedings of the KIEE Conference
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    • 1987.07b
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    • pp.1217-1220
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    • 1987
  • We have developed a Ultra Sound Pulsed Doppler System with two-dimensional M-mode image and Spectrum analyzer. The image of the M-mode is composed of time and depth axes. The Spectrum analyzer shows the spectrum of Doppler signal which represents the velocity component of time dependent blood-flow behavior. The spectrogram using Spectrum analyzer is composed of frequency and amplitude axes. The outputs of the system are audio signals, velocity curves, velocity profiles, M-mode images and spectrogram.

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Echo-PIV: in vivo Flow Measurement Technique (에코 PIV: in vivo 유동 측정기법)

  • kim Hyoung-Bum;Hertzberg Jean;Shandas Robin
    • Journal of the Korean Society of Visualization
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    • v.3 no.1
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    • pp.26-35
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    • 2005
  • The combination of ultrasound echo images with digital particle image velocimetry (DPIV) method has resulted in a two-dimensional, two-component velocity field measurement technique appropriate for opaque flow conditions including blood flow in clinical applications. Advanced PIV processing algorithms including an iterative scheme and window of offsetting were used to increase spatial resolution. The optimum concentration of the ultrasound contrast agent used for seeding was explored. Velocity validation tests in fully developed laminar pipe flow and pulsatile flow showed good agreement with both optical PIV measurements and the known analytic solution. These studies indicate that echo PIV is a promising technique for the non-invasive measurement of velocity profiles and shear stress.

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