• Fisheries and Aquatic Sciences
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• 제22권5호
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• pp.9.1-9.7
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• 2019

The study investigated the changes in growth performance, hematological parameters, plasma components, and stress indicators of juvenile starry flounder, Platichthys stellatus, depending on varying exposure to hexavalent chromium. P. stellatus was exposed to waterborne chromium at 0, 50, 100, 200, and 400 ppb for 4 weeks. The result showed that Cr exposure resulted in decreased daily length gain (DLG), daily weight gain (DWG), condition factor (CF), and hepatosomatic index (HIS) in P. stellatus. In terms of hematological parameters, red blood cell (RBC) count, hematocrit (Ht), and hemoglobin (Hb) significantly decreased at 400 ppb after 2 weeks. In terms of plasma components, inorganic analysis was unchanged and cholesterol, an organic component, considerably increased at 400 ppb after 4 weeks. Plasma enzyme components including glutamic oxalate transaminase (GOT) and glutamic pyruvate transaminase (GPT) were significantly increased. Stress indicators such as cortisol and glucose were notably increased over 100 ppb after 4 weeks with increasing chromium concentration. The results indicate that exposure to waterborne Cr induced toxic effects on growth, hematological parameters, plasma components, and stress indicators.

• Asian Pacific Journal of Cancer Prevention
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• 제15권18호
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• pp.7603-7609
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• 2014

Glutathione is a thiol compound that plays an important role in the antioxidant defense system of the cell and its deficiency leads to an increased susceptibility to oxidative stress and, thus, progression of many disease states including head and neck cancer. In the present study, alterations of glutathione levels were investigated in study cohort of 500 samples (cohort 1 containing 200 head and neck cancer blood samples along with 200 healthy controls and cohort II with 50 head and neck squamous cell carcinoma tissue samples along with 50 control tissues) by high performance liquid chromatography. The results indicated that mean blood glutathione levels were significantly reduced in head and neck cancer patients (p<0.001) compared to respective controls. In contrast, the levels of glutathione total (p<0.05) and glutathione reduced (p<0.05) were significantly elevated in head and neck squamous cell carcinoma tissues compared to the adjacent cancer-free control tissues. In addition to this, pearson correlation performed to correlate different tissue glutathione levels (GSH) with clinical/pathological parameters demonstrated a significant negative correlation between pT-stage and GSH level ($r=-0.263^{**}$; p<0.01), C-stage and GSH level ($r=-0.335^{**}$; p<0.01), grade and GSH ($r=-0.329^{**}$; p<0.01) and grade versus redox index ($r=-0.213^{**}$; p<0.01) in HNSCC tissues. Our study suggests that dysregulation of glutathione levels in head and neck cancer has the potential to predict metastasis, and may serve as a prognostic marker.

• Asian-Australasian Journal of Animal Sciences
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• 제26권6호
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• pp.879-885
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• 2013

Fifty-four, mixed-sex, halothane-carrier crossbred (Yorkshire${\times}$Landrace) pigs with an average initial BW of $108.2{\pm}0.8$ kg were randomly allotted to one of three dietary treatments for 5 d before slaughter: i) a control corn-soybean meal finisher diet devoid of supplemental magnesium; ii) a diet supplemented with 1.5 g/kg of elemental Mg from magnesium acetate; and iii) a diet supplemented with 1.5 g/kg of elemental Mg from magnesium sulfate heptahydrate. Serum creatine kinase (CK), lactate and glucose were analyzed at slaughter. Muscles from longissimus (LM) were packaged and stored to simulate display storage for muscle lactate and glycogen determinations at 0, 1, 2, 3, and 4 d. Mg supplementation reduced (p<0.05) serum CK and lactate concentration, but had no effect (p>0.05) on serum glucose. Daily change of muscle lactate concentration linearly increased (p<0.01), while glucose concentration linearly decreased (p<0.05) as storage time increased in all treatments. However, dietary Mg acetate and Mg sulfate supplementation in pigs elevated (p<0.05) muscle glycogen and reduced (p<0.05) muscle lactate concentrations, especially during the first 2 d of display, compared with pigs fed the control diet. This study suggests that short-term feeding of magnesium acetate and magnesium sulfate to heterozygous carriers of the halothane gene has beneficial effects on stress response and pork quality by improving blood and muscle biochemical indexes.

• 한국환경과학회지
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• 제21권12호
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• pp.1487-1494
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• 2012

This study has been carried out to verify curative effect of lavender and lawn, a green space composition factor. Thus, the physiological index value of blood pressure, heart rate and salivary amylase were measured with object of 16 women in their 20~30s for stress relaxation effect at lavender garden and lawn square, and impression assessment upon SD method as for psychological value was performed in this study. And a survey was conducted on necessity and reason of urban green space with object of 345 men and women urban workers. As a result of variance analysis between groups and multi test of Turkey upon object place, the blood pressure was lowered the same at lavender garden and lawn square, and especially, high blood pressure was greatly lowered to 30 mmHG at lavender garden. On the other hand, low blood pressure group showed the tendency of a little increasing at the same places. And for the pulse, there was difference between high blood pressure group and normal group at the same places. To conclude, at lavender garden and lawn square the blood pressure was made to be lowered when it's high, and when it's low, the effect of returning to sound status, the function of increasing, was verified. In case of impression assessment upon SD method, the lawn square was assessed as resting place and lavender garden diversional place. And over 90% of urban workers responded to the green space's necessity and curative effect, diversion and resting place were adopted for the reason in high-ranking items. As above the green space pattern that urban workers require and curative effect of lavender garden and lawn square were verified. Therefore, the functional green space plan is required, which curative effect, diversion and resting place are considered, for the future green space plan design.

• Journal of Yeungnam Medical Science
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• 제8권1호
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• pp.63-71
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• 1991

저자들은 1990년 5월 1일부터 1991년 4월 30일까지 영남대학교 의과대학 부속병원 산부인과에 정기검진을 위해 내원한 157명의 정상 임산부를 대상으로 제대동맥에서 시행한 도플러초음파 160회의 검사 결과를 엄신 주수에 따라 분석하여 다음과 같은 결과를 얻었다. 제대동맥의 최고 수축기 혈류속도는 임신이 진행함에 따라 증가 양상을 보임으로써 임신이 증가함에 따라 제대 동맥 혈류량은 증가함을 관찰할 수 있었다. 임신이 진행함에 따라 제대태반 순환계 말초 저항이 점차적으로 감소함으로 인해 제대동액 이완기말 혈류속도도 중가 양상을 보였다. S/D ratio는 최고 수축기 혈류속도의 증가에도 불구하고 이완기말 혈류속도의 점차적인 증가로 인하여 임신이 진행함에 따라 오히려 감소함을 관찰할 수 있었다. 임신이 지속함에 따라 PI, RI도 감소하는 양상을 보였다.

• Journal of Animal Science and Technology
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• 제64권5호
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• pp.970-984
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• 2022

Thermal stress is a tremendous health predicament encountered by poultry farmers with adverse effects on the performance, product stature, health condition, survival, and overall welfare of poultry birds, and so requires urgent dietary user-friendly strategy to curb. This study was conducted with 200-day old broilers for the purpose of investigating the potential of phytogenics in refining the negative effects of heat stress on broiler chicken. Moringa, Phyllanthus and mistletoe leaves were processed as phytogenic supplements and incorporated into standard ration for broilers as treatments B1 (control), B2, B3 and B4 diet during the peak of thermal discomfort in humid tropics. Growth and carcass indices were monitored in a 49-day trial and blood samples were harvested at the end of the ordeal period to assess haematology, serum biochemical and oxidative stress markers with the use of standard procedures. The results obtained showed that the prevailing environmental condition in the study site indicated that the birds were exposed to heat stress. Birds fed on moringa and mistletoe supplements had higher performance index than birds without supplementation during heat stress condition, while birds fed on mistletoe supplement had the highest survival rate across the treatments. The liveweight, slaughter weight, dressed weight and eviscerated weight of heat stressed birds fed on moringa, phyllanthus and mistletoe supplements were significantly higher than birds on control treatment. Heterophyl/lymphocyte ratio of heat stressed birds without supplement were higher than birds on phytogenic supplements, with least values recorded in phyllanthus and mistletoe fed birds. Birds on phytogenic supplement tend to have lower cholesterol profile, lipid peroxidation and better antioxidant profile than birds on control treatment during heat stress conditions. Mistletoe supplementation in broiler ration enhances the survival rate, as well as promotes growth indices better among the phytogenic supplements. However, phytogenic supplements did ameliorate the negative effects of thermal discomfort on performance, physiological and oxidative stress in heat-stressed broiler chicken.

• Journal of Nutrition and Health
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• 제45권2호
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• pp.127-139
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• 2012

본 연구는 비만연구소 복부비만관리 프로그램에 참여한 복부비만율 0.80 이상인 복부비만 여성 195명을 대상으로 12주간 실시하였으며, 프로그램 종료 후 복부비만 감소 여부에 따라 복부비만율 감소군과 복부비만율 증가군으로 나누어 신체계측치의 변화, 식이섭취의 변화, 혈관나이, 스트레스 지수 및 건강지수의 변화를 비교 하였다. 영양소의 섭취량을 살펴본 결과, 체중, 허리둘레, 엉덩이둘레가 유의적으로 감소한 복부비만율 감소군에서 식물성 단백질, 칼륨, 비타민 A, 엽산, 식이섬유, 칼슘, 인, 비타민 $B_2$, 비타민 $B_6$, 비타민 C, 식물성지방, 철분, 나트륨, 나이아신, 비타민 E 및 다가불포화지방산의 영양밀도가 유의적으로 증가하였고, 단백질, 칼슘, 인, 비타민 A, 비타민 $B_1$, 비타민 $B_2$ 그리고 비타민 C의 INQ가 유의적으로 증가하였다. 특히 식이섬유, 칼슘, 인, 아연, 비타민 $B_6$, 비타민 C 그리고 비타민 E의 변화율은 복부비만율 감소군에서 더 컸으며, 두 그룹간의 유의적인 차이를 보였다. 식품섭취 다양성의 변화를 살펴보기 위해 식품군별 섭취 가짓수를 비교해 본 결과, 복부비만율 감소군에서 어패류, 두류, 견과류, 채소류 그리고 버섯류 가짓수가 유의적으로 증가한 것으로 나타났다. 복부비만율 감소군에서는 스트레스 지수와 건강지수가 유의적으로 개선된 반면 복부비만율 증가군에서는 건강지수가 감소하였다. 본 연구에서는 복부비만율 변화와 영양밀도, 혈관나이, 스트레스 지수 및 건강지수 변화간의 상관성을 알아보았다. 그 결과, 복부비만율 감소의 변화율이 높을수록 식물성 단백질, 식물성 지질, 섬유질, 칼슘, 철분, 칼륨, 아연, 비타민 A, 비타민 $B_2$, 비타민 $B_6$, 비타민 C 그리고 엽산의 섭취량이 유의적으로 감소하였고, 복부비만율 증가의 변화율이 높을수록 동물성 단백질과 총 지질의 섭취량이 유의적으로 증가하였다. 스트레스 지수와 건강지수와의 관련성에서는 복부비만율 감소율이 높을수록 스트레스 지수가 유의적으로 감소하는 양의 상관관계를 보인 반면, 건강지수는 증가하는 음의 상관관계를 보였다. 이상을 통해 볼 때, 영양교육과 식습관 및 생활습관 개선 교육으로 구성된 복부비만관리 프로그램은 식이섭취에 긍정적인 영향을 미칠 뿐만 아니라 스트레스도 완화시켜 복부비만율 개선에 도움이 되므로, 후속 연구에서는 이러한 교육을 장기프로그램에 적용시킨 뒤 이러한 복부비만율 개선이 지속적으로 유지되는 지를 살펴보는 것이 필요하다.

• 여성건강간호학회지
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• 제14권4호
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• pp.270-277
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• 2008

Purpose: Although Hemophilia is a relatively rare hereditary disease, and is treatable with blood products, the parenting stress and guilt of hemophilic patients and their mothers are always high. This study was done to assess the extent of parenting stress, guilt, parenting attitude and parenting satisfaction of mothers with a hemophilic child. Method: The participants in this study were 119 mothers with a hemophilic child who were registered members of the Korea Hemophilia Foundation, and 287 mothers with a healthy child. In order to measure the dimensions related to parenting stress, guilt, parenting attitude and parenting satisfaction, the Questionnaire on Parenting Stress Index, Maternal Guilt Scale, Parenting Attitude Scale & Parenting Satisfaction Scale were administered. We analysed the differences between mothers with a hemophilic child and a healthy child in the questionnaire scores using the SPSS program. Result: Parenting stress and guilt of mothers with a hemophilic child were higher than with a healthy child. Parenting attitude and parenting satisfaction of mothers with a hemophilic child were lower than with a healthy child. Conclusion: The results may help medical professionals understand mothers with a hemophilic child and give basic assistance to develop a nursing intervention by exploring possible ways to alleviate such parenting stress and guilt.

• 대한암한의학회지
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• 제16권1호
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• pp.15-31
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• 2011

Objective : The study aims to investigate the effect of moxibustion treatments on autonomic nervous system function of cancer patients through the evaluation of heart rate variability (HRV) biofeedback testing. Materials and Methods : Six cancer patients from inpatient care unit of Dunsan Oriental Hospital, Daejeon University were given three moxibustion treatment sessions every other day over one week period on five Oriental Medicine meridian points CV4, CV6, CV12, KD1, and PC8. HRV biofeedback was conducted before and after each treatment sessions. Three areas of analyses were done from the test conducted; Time Domain Analysis, Frequency Domain Analysis and Autonomic Nervous System (ANS) balance analysis. Results : Time Domain Analysis has shown increased Standard Deviation of all Normal R-R Intervals (SDNN), and decreased Mean Heart Rate and Physical Stress Index (PSI) levels, with statistical significance (P<0.05). In Frequency Domain Analysis, series of moxa treatments have increased Total Power (TP), Very Low Frequency Oscillation Power (VLF), High Frequency Oscillation Power (HF), normalized HF values while decreasing Low Frequency Oscillation Power (LF), normalized LF and LF/HF ratio with statistical significance (P<0.05). The values of ANS activity, ANS balance, Stress resistance, Stress index, have also shown significant changes. For cardiac stability stroke volume power (SP) and Blood Vessel Tension (BVT) were followed, which were both increased after treatment. All changes were statistically significant (P<0.05). Conclusion : The results have shown a positive correlation between the moxibustion treatments and autonomic nervous system responses on cancer patients through the HRV biofeedback testing. This study suggests possible application of moxibustion treatments for managing ANS functions of cancer patients, although additional studies with larger population are necessary to confirm the data.

• Journal of Preventive Medicine and Public Health
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• 제35권2호
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• pp.169-174
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• 2002

Objective : To investigate gamma-Glutamyltransferase (${\gamma}-GTP$) and its related factors in male industrial workers. Method : Five hundred and tony male workers without heart disease, diabetes mellitus, renal disease, hepatitis, and other liver diseases were surveyed in October 1998. Blood samples were collected to test for ${\gamma}-GTP$, total-cholesterol and fasting blood glucose. A self-administered questionnaire survey on life style was also done. Results : The total geometric mean value of ${\gamma}-GTP$ was 30.6 U/L. According to a univariate analysis: age, BMI(body mass index, $kg/m^2$), alcohol consumption, current smoking, stress, diastolic blood pressure, and blood total cholesterol were significantly associated with ${\gamma}-GTP$(p<0.05). From a multiple regression analysis: BMI, alcohol consumption, current smoking, diastolic blood pressure and total-cholesterol were significantly related to ${\gamma}-GTP$(p<0.05). Coffee consumption was negatively related to ${\gamma}-GTP$, but not significantly. Conclusion : We recommend that a change in health behavior (i.e. reducing alcohol intake, controlling BMI and not smoking) is necessary to decrease ${\gamma}-GTP$ in male workers.