• Korean Journal of Community Nutrition
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• v.5 no.2
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• pp.172-184
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• 2000

To establish a basic cohort which can survey the nutrient and food intake related to the health status of the middle and old-aged vertically, a longitudinal survey of 110 adults over forty years old was conducted three times in Chon-ju city over 5 years (1994-1999), and the influences of health status by changes in their nutrient and food intake were examined in this study. The results were as follows ; The number of subjects was 110(43 man, 67 women), 10.0% in their forties, 28.2% in their fifties, 45.4% in their sixties 6.4% over seventy, and their average age was 61.4. There were decrease of height about 1cm , increase of body fat % and few changes of BMI during the testing period. As the subjects were aging, the percentage of anemia increased, but averages of blood pressure and blood glucose(men : 91.8mg/㎗, women : 90.3mg/㎗) were constant. Total cholesterol increased from 196.7mg/㎗ to 212.6mg/㎗(P 0.05) over five years, and the numerical values for women were higher than that of men. In many cases, lack of nutrient intake was shown, as compared with the Recommended Dietary allowance(RDA) especially calcium and vitamin A(71.7%, 64.9% of RDA). Grains intake showed a tendency to decrease(P 0.01). On the contrary, fruit intake showed a tendency to increase(P 0.001). On whole meal, plant foods were 85.1% and animal foods were 14.9%. As dietary factors influencing health status were investigated, blood glucose was influenced by vitamin B$_2$, potatoes and triglyceride, DBP and SBP were affected by vitamin B$_1$, vitamin C, legumes, fishes, triglyceride and age. Total cholesterol was under the influence of triglyceride, milk, seeds and fat. BMI was influenced by iron, SBP, animal food, and age.

• Korean Journal of Clinical Laboratory Science
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• v.52 no.4
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• pp.327-334
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• 2020

The present study was conducted to assess the relationship between metabolic syndrome, metabolic syndrome score, homeostasis model assessment of insulin resistance (HOMA-IR), and beta-cell function (HOMA-B) in obese Korean adults. The study included 1,860 adults aged 20 years or older from the 2010 Korean National Health and Nutrition Examination Survey (KNHANES) data. Metabolic syndrome and metabolic syndrome score (MSS) were positively associated with HOMA-IR (both P<0.001). HOMA-B levels of elevated blood pressure (P<0.001) and elevated fasting blood glucose group (P<0.001) were significantly lower than the normal group. However, the HOMA-B levels of abdominal obesity (P=0.003) and reduced high-density lipoprotein cholesterol group (P=0.030) were significantly higher than the normal group. Nevertheless, metabolic syndrome (P<0.001) and MSS (P<0.001) were inversely associated with the HOMA-B levels. In conclusion, metabolic syndrome and MSS were positively associated with insulin resistance and inversely associated with beta-cell function in Korean adults with obesity.

• Journal of East-West Nursing Research
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• v.19 no.1
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• pp.23-29
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• 2013

Purpose: This study was conducted to investigate how information using leaflet will affect anxiety of inpatients undergoing endoscopic examination. Methods: Non-equivalent control group with a pre-post test design was used. Subjects were selected from inpatients of D hospital in B city for endoscopic examination from May 1 to July 31, 2009. Forty subjects were assigned to either control or experimental group. The Leaflet developed by authors was used as an educational material. Johnson's visual analogue scale, blood pressure, and pulse were used to measure anxiety. Results: The experimental group informed with the leaflet showed less subjective anxiety than control group without the leaflet (p=.008). Experimental group informed with the leaflet showed less objective anxiety measured by systolic blood pressure, diastolic blood pressure, and heart rate than control group without the leaflet (p=.004, .014, and .009, respectively). Conclusion: Giving information using leaflet to the patient before endoscopy may be applicable as a nursing intervention to reduce anxiety. Further studies are needed to generalize the results of this study.

• Journal of Physiology & Pathology in Korean Medicine
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• v.31 no.2
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• pp.118-125
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• 2017

The purpose of this study is to investigate the blood pressure reducing effect of Qi-Ju-Di-Huang-Wan (QJDHW) in adults with essential hypertension by using methods of systemic review and meta-analysis. Major search engines, such as PubMed, EMBASE, Cochrane library, Web of Science, CNKI, CiNii, J-STAGE, KISS, NDSL, RISS, OASIS, DBpia and so on, were used. The search period we used is from the start date of the search engine to October 30, 2016 and no language limits were placed. Randomized controlled trials using QJDHW in adults with essential hypertension were searched and extracted by two independent researchers. Meta-analysis was performed on outcome variables of the total effective rate (TER), systolic blood pressure (SBP) and diastolic blood pressure (DBP). Risk of bias (RoB) of Cochrane was used to assess methodological quality. Thirteen studies were finally selected. We observed that the combined treatment of QJDHW and antihypertensive drug had 3.6 times the odds ratio of TER for blood pressure lowering than a single use of an antihypertensive drug. Additionally, mean differences of SBP and DBP were -8.88 mmHg (95% Confidential Interval (CI) -12.77 mmHg, -5.00 mmHg, P<0.00001), -7.09 mmHg (95% CI -9.93, -4.25, P <0.00001), respectively. Single use of QJDHW did not reduce blood pressure more than an antihypertensive drug. All items of RoB were unclear and the methodological quality was low. Our analysis suggests that the combination of QJDHW and antihypertensive drugs may be more effective in reducing blood pressure than a single antihypertensive drug. But due to low methodological quality, careful interpretation will be needed and systematic long-term clinical trials will be required.

• Journal of the Korean Society of Food Culture
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• v.35 no.5
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• pp.493-502
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• 2020

The objective of this study was to investigate the effects of dietary vitamin B intake on biomarkers related to lipid metabolism, inflammation and blood glucose control, that are important in the development of type 2 diabetes and its complications. Seventy-six adults (42 males, 34 females) were recruited from a group of diabetes patients who had visited the medical center for treatment. Data on anthropometric characteristics and dietary intake of thiamine, riboflavin, niacin, vitamin B₆ and folate were collected using 24-hour diet recall and the CAN Pro 4.0 program. Also, data on clinical indices such as serum lipids, blood pressure, high-sensitivity C-reactive protein (hs-CRP), hemoglobin A1c (HbA1c) and homeostasis model assessment 2-insulin resistance (HOMA2-IR) were collected and analyzed for correlation with dietary vitamin B intake. Results from the dietary intake survey showed that riboflavin and folate intake (in males) and folate intake (in females) were below the Dietary Reference Intake for Koreans. Statistical analysis revealed a negative correlation between hs-CRP and dietary intake of B vitamins. Riboflavin intake was inversely associated with systolic blood pressure after adjustments for age, BMI, smoking, alcohol consumption, exercise, ingestion of diabetes mellitus medication and energy intake (p<0.05). Our results suggest that dietary vitamin B may influence inflammation and consequently may help in better management of type 2 diabetes.

• Journal of Nutrition and Health
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• v.30 no.3
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• pp.277-285
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• 1997

The purpose of this study was to investigate the relationship among nutrient intake, life style, and serum lipids level in 108 healthy middle-aged men in Taegu. A convenient method was to assess nutritional intake. Anthropometric measuement of body weight and hight were measured and average energy expenditure was calculated. The mean body mass index(BMI) was 22.8$\pm$2.4 and it was in the middle of the mean BMI of Korean men. Obesity rate of study subject were 13.2%. Daily energy intake was not sufficient as 88.4% of recommended dietary allowances and the energy percentage of carboydrate, fat protein was 65 : 21 : 14. Mean intake of vitamin A, B1, C and Ca were lower than RDA. There was a highly significant negative correlation between the systolic blood pressure and calcium intake(r=-0.28, p<0.05). Smokers showed significantly higher blood glucose than non-smokers. Skipping meals and uneven diurnal distribution(no breakfast and large evening meals) are associated with high triglyceride level in this population. There was a highly significant correlation between body weight and plasma lipids. Energy expenditure was negatively correlated with plasma triglyceride level. Especially, atherogenic index was significantly lower in job-time physically active worker than that in sedentary worker. Above data provides valuable imformation to the community for program planning as well as to health providers who work individual male adults to meet their nutrition needs and to control blood lipids.

• Journal of the East Asian Society of Dietary Life
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• v.25 no.3
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• pp.417-424
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• 2015

The purpose of this study was to investigate daily nutrient intakes, serum minerals and lipids in university students majoring in physical education. Anthropometric measurement, dietary survey, and blood analysis were conducted and compared between physical education major (PM) and other major (OM) students. Average age was 21.3 years for PM students and 20.8 years for OM students. Body weight and BMI of PM students were significantly higher than those of OM students (p<0.05). Systolic blood pressure of PM students was significantly lower than that of OM students (p<0.05). Daily energy intake was 2,047.4 kcal for PM students and 2,393.9 kcal for OM students, indicating a significant difference. Carbohydrate and vitamin B1 intakes of PM students were significantly lower than those of OM students. Serum calcium was significantly higher in PM students while serum phosphorus and magnesium levels were higher in OM students. Serum total cholesterol and LDL-cholesterol were significantly lower in PM students while HDL-cholesterol was lower in OM students. In conclusion, university students who major in physical education showed higher serum calcium, lower serum phosphorus and magnesium, and lower systolic blood pressure and serum cholesterol levels than other major students. These results show that physical activity as a major course of study is associated with decreased blood pressure and blood lipids as well as altered serum mineral levels.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1819-1822
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• 2012

Background: In the United Arab Emirates (UAE) tobacco use is rampant. A less reported, yet widely used form of smoking native to UAE is midwakh or dhokha. The aim of the study is to assess the acute effects of smoking dokha (Arabian pipe) on the cardiovascular and respiratory systems among male university students in the UAE. Method: A quasi-experimental study was conducted among 97 male volunteers aged more than 17 years. Blood pressure, heart rate and respiratory rate of each participant, were measured before and immediately after smoking. A self administered questionnaire was used to collect personal details and data about smoking pattern. Results: Mean increases in systolic blood pressures ($12{\pm}1$ mmHg), heart rates ($20{\pm}2$ bpm) and respiratory rates ($4{\pm}1$ breaths/min) were observed (p < 0.001). A mean decrease in diastolic blood pressures ($1{\pm}1$ mmHg) was observed (p = 0.483). Conclusion: Smoking dokha has a significant acute effect on systolic blood pressure, heart rate and respiratory rate. Anti smoking campaigns must address the ill effects of this form of smoking. Results from the study warrant further research into this method of smoking which is becoming more popular.

• Journal of Nutrition and Health
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• v.36 no.1
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• pp.64-74
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• 2003

The purpose of this study was to investigate the distribution patterns of serum triglyceride and cholesterol levels and the influence of environmental and dietary factors in 201 healthy male subjects. The subjects were found to be 53.7% for the normal, 15.4% for the TC, 17.4% for TG and 13.5% for TC.TG group, respectively. Among general characteristics, smoking significantly affected serum lipid levels of subjects (p < 0.05). Among anthropometric factors, body weight, BMI and PIBW significantly influenced the blood lipid patterns. Body weight of TG group was significantly higher than that of normal group (p < 0.05). BMI and PIBW of TG group and TC.TG group were significantly higher than those of normal group (p < 0.05) . In addition, diastolic blood pressure of TG group was significantly higher than that of normal group (p < 0.05). For the food intake, average intake of fruit was significantly higher in normal group than that of TG group (p < 0.05). For nutrient intake, calcium intake was significantly higher in TC group than those of normal and TC.TG group (p <0.05). Intakes of vitamin $B_2$ and C were significantly higher in TC group than those of in TG group (p < 0.05). Serum HDL-cholesterol level was negatively related to meat, poultry, and their products (p <0.05), but serum total cholesterol level positively related to animal lipids (p < 0.05). The results of this study suggest that it is crucial for maintaining adequate serum lipid levels to reduce smoking, blood pressure and to lose body weight. As far as food intake concerned, fruit intake was important in maintaining serum triglyceride level normal, while animal food intake affected serum total cholesterol level adversely. (Korean J Nutrition 36(1): 64-74, 2003)

• The Journal of Internal Korean Medicine
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• v.25 no.2
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• pp.195-201
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• 2004

Background and Purpose : Hypertension is one of the modifiable risk factors for stroke. Lowering blood pressure is a primary or secondary preventative measure for stroke. This study aims to assess the efficacy of Chunghyul-dan(Qingxue-dan) in stage 1 hypertensive patients who have suffered a stroke by 24 hour ambulatory blood pressure monitoring(24ABPM). Subjects& Methods : We enrolled 40 hospitalized stroke patients with stage 1 hypertension and divided them into 2 groups by stratified randomization; group A took 1200mg of Chunghyul-dan(Qingxue-dan) at 8:00 a.m. for two weeks without changing herbal medicine, and group B was the control group. 28 patients were included in the final analysis(15 in group A. 13 in group B). Blood pressure is monitored from 8:00 am to 7:30 am every 30 minutes for 24 hours. Blood pressure was monitored two times at baseline and again two weeks later. We used 3 parameters for evaluating the efficacy of Chunghyul-dan(Qingxue-dan); The first parameter is change from baseline to two weeks later in blood pressure and pulse rate. The second parameter is the trough/peak ratio(TPR) and smoothness index(SI). The third parameter is antihypertensive rate by antihypertensive efficacy guideline. Results : There is no significant difference in the baseline assessment hetween the two groups. Systolic blood pressure $(141.37{\pm}8.96\;mmHg\;vs\;132.28{\pm}9.46\;mmHg)$ decreased after two weeks of 1200mg(P=0.03) intake of Chunghyul-dan(Qingxue-dan). Systolic TPR and SI was 0.87 and 1.04 in group A. Antihypertensive rate was higher in group A. Conclusion: These results suggest that 1200mg doses of Clunghyul-dan(Qingxue-dan) is an effective antihypertensive agent on stage 1 hypertension patients who have suffered a stroke.