• 재활간호학회지
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• 제6권2호
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• pp.226-238
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• 2003

This study was started for the purpose of providing the basic data for continous managment of kidney transplantation patients after discharge. This study was conducted on 180 patients who received renal transplants at three hospital( B, M, P) pusan, korea. The data collection was done for june 1, to August 31, 2002. General characteristics, renal transplantaton characteristics, physical characteristics, the level of compliance and the degree of educational demand were done by the number and percentage, the mean, standard deviation. The level of compliance and educational demand followed by the characteristics of general and kidney transplantation were analyzed by t-test and ANOVA. The result were as fallows; 1. Man was higher than woman such as 60.0%, Mean age was 42.5 years old, Average total duration of after operation was 5.5 years. 2. Cases of systolic blood pressure over 140mmHg were 10.0%, cases of diastolic blood pressure over 90mmHg were 22.8% and obesity factor in BMI was 15.6%. The person who daily water intake amount is 5000cc was 0.6%, the case that daily urine output is below 1000cc was 8.9%, and the case that urine output is zero was 0.6%. 3. The mean score of compliance was 77.47 point, The score in medication part was highest such as 4.67 point, that in stress situation was lowest such as 3.50 point. 4. The average score of educational demand was 154.02 point, and physical state part was 4.36 points highest, activation part was 3.48 points lowest. As a role of nurse Confirmation of compliance is very important encourage to make good through regular hospital visitation, point out the noncompliance part and then increase compliance of renal transplantation patient As well there will be maintain the normal kidney function to satisfy educational demand through continous education.

• Korean Chemical Engineering Research
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• 제49권2호
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• pp.238-243
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• 2011

본 연구는 기존의 인공심폐기의 단점을 보완하기 위하여 혈액펌프를 사용하지 않고 혈류의 흐름을 유도할 수 있는 기구(balloon)형 인공심폐기 설계를 위한 구조적 해석을 시도하였다. 가상의 모형 인공심폐기 내에서의 혈류의 흐름패턴을 분석하기 위하여 CFD 모델링 방법을 사용하였다. 이 시스템의 작동원리는 막 산화기 주위를 기구를 사용하여 압력하중을 인가하여 주기적으로 수축.이완되도록 하였으며, 시간에 따라 변화하는 시간 함수 값은 sine 반주기와 sine 주기를 계산하여 적용하였다. 이와 같은 방법으로 기구형 인공심폐기를 설계할 경우 한 방향에 대한 혈류의 움직임을 유도할 수 있다는 가정 하에 구조적 해석을 하였다. 실험결과 CFD 시뮬레이션을 통하여 인공심폐기의 입구와 출구에 서의 혈류의 속도와 압력을 측정하여 분석한 결과 한 방향에 대한 혈류의 유동이 발생하는 것을 확인하였다. 이와 같은 CFD 시뮬레이션은 혈류의 흐름특성을 미리 예측할 수 있어 인공심폐기 설계에 있어서 최적화된 디자인을 제공할 수 있을 것이라 판단된다.

• 한국산학기술학회논문지
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• 제10권9호
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• pp.2516-2522
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• 2009

본 연구는 혈액에서 분리되는 미생물의 균종과 항균제 감수성 검사 결과 양상은 환자의 일반적 특성에 따라 다르므로 혈액배양 결과를 분석한 자료는 감염증 환자의 경험적 치료를 위한 중요한 근거가 되고, 특히 ESBL을 생성하는 균주의 경우 항균제의 사용과도 밀접한 관련이 있어 이 연구를 하게 되었다. 혈액배양 결과와 항균제 내성 결과를 분석한 결과는 다음과 같다. 1. 39.305건의 혈액배양이 의뢰되어 양성 환자 수는 2,216명(20.0%)이었고, 이중에서 ESBL양성 환자 수는 40명 이었으며, 혈액배양 양성은 4,798건(12.2%)이었으며 ESBL양성 균주는 86건(중복 배양 균주 포함)이었다. 2. ESBL을 생성하는 세균 중에서 분리된 균종은 E. coli, K. pneumoniae, K. oxitoca의 순 이었다. 3. 성별로는 여자가 다소 많았고, 연령별로는 50세 이상의 군에서 E. coli, 1세 미만의 군에서는 K. pneumoniae, K. oxitoca 의 분리가 많았고, 지역별로는 충청남도 13명(32.5%)로 가장 많았다. 4. 3년간 일개대학병원의 혈액배양에서 ESBL양성인 균종 중 가장 흔히 분리되는 것은 E. coli이고, K. pneumoniae, K. oxitoca 등이 다음으로 분리 되었고, 50세 이상의 환자에서 E. coli의 분리 비율이 높았다.

• 대한한방내과학회지
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• 제44권3호
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• pp.354-365
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• 2023

Objective: This study aimed to assess the safety and effect on glucose level of Bojungikgi-tang in patients with type 2 diabetes mellitus. Methods: To review patients' clinical characteristics and laboratory tests retrospectively, we investigated 15 hospitalized patients with type 2 diabetes mellitus who took Bojungikgi-tang at Kyung Hee University Korean Medical Hospital for at least one day between January 2012 and December 2022. The blood glucose levels, including fasting blood sugar (FBS), 2-hour postprandial glucose (PP2) levels, and glycated hemoglobin level, were collected to determine the effect of the Bojungikgi-tang on blood sugar changes. Furthermore, to evaluate the safety of Bojungikgi-tang, hepatic function and renal function tests were implemented, including aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, γ-glutamyltransferase, blood urea nitrogen, creatinine, and Modification of Diet in Renal Disease estimated glomerular filtration rate. Results: When Bojungikgi-tang and a standard treatment for diabetes were administered for patients with type 2 diabetes, it was confirmed that there were no statistically significant changes in FBS and PP2 levels in the analysis of each medication taken. There was no significant difference in the safety profile after taking Bojungikgi-tang. Conclusions: The combined administration of Bojungikgi-tang with standard hypoglycemic medication for patients with type 2 diabetes may not affect blood glucose levels and safety.

• 한국가금학회지
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• 제34권2호
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• pp.105-110
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• 2007

본 연구는 육계의 개방 계사에서 사육 밀도에 따라 고밀도(0.050$m^2$/수), 관행(0.066$m^2$/수), 저밀도(0.083$m^2$/수) 사육구로 구분하여 사육 밀도가 여름철 육계 생산성에 미치는 영향을 평가하고자 실시하였다. 공시계는 육계 초생추 Ross로서 684수를 이용하였으며, 5주간 사양 시험을 실시하였다. 기초 사료 영양소 함량은 사육 전기($0{\sim}3$주)에 ME 3,100 kcal/kg, CP 22.0%, 후기($4{\sim}5$주)에는 각각 3,100 kcal/kg, 20.0%로 하였다. 사육 밀도에 의한 육계의 체중은 5주령에 고밀도 처리구인 T1이 관행적인 T2와 저밀도구인 T3 처리구에 비해 유의적으로(P<0.05) 감소하였다. 사료 섭취량도 체중의 변화와 동일한 결과를 보였다. 사료 요구율은 관행적인 T2 처리구에서 유의적으로(P<0.05) 개선되었다. 음수 섭취량과 깔짚 수분 함수율은 시험 전 기간동안 처리구간에 통계적인 차이가 없었다. 혈청 성분의 분석결과에서는 total protein, cholesterol 및 albumin의 수치가 T3에서 낮은 경향이었으나 유의성은 인정되지 않았다. 본 연구 결과 육계의 사육 밀도 증가는 생산성을 감소시키며 개체에 스트레스를 증가시켜 폐사율의 증가와 도체 품질을 저하시킬 수 있는 가능성을 시사하였다.

• 한국생산제조학회지
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• 제22권1호
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• pp.45-49
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• 2013

It is important to have a well developed strain energy function in order to understand the mechanical behavior of biomaterial like the blood vessel of artery. However, since it is not possible to have a complete form of strain energy function of artery, theoretical framework describing the behaviour of Rubber-like material which is similar to blood vessel is applied to infer useful forms of strain energy function of biomaterial. Based on Chuong-Fung model and Mooney-Rivlin model, material parameters are estimated based on experimental data. From the results, it can be inferred that the estimated parameters can be used to explain the difference of mechanical characteristics between normal vessel and vessel with stent.

• 대한의생명과학회지
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• 제14권4호
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• pp.275-281
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• 2008

Plasma fibrinogen is risk factor of vascular disease including stroke, ischemic heart disease, atherosclerosis and thrombosis. Many studies have confirmed that high plasma fibrinogen levels are related with age, obesity, cholesterol, alcohol consumption, and genotype. This study was carried out to investigate the effect of fibrinogen genotype and other characteristics on the plasma fibrinogen levels in the elderly Koreans. For this study the blood samples were collected from 178 healthy elderly Koreans (102 males and 76 females, $55{\sim}80$ year olds). The blood samples were analyzed by smoking status, cholesterol levels, genotype, age, exercise, drinking, and gender. The plasma fibrinogen was assayed by clotting method, cholesterol being assayed by cholesterol oxidase method. The $\beta$-fibrinogen genotype was detected by PCR of relevant region and digestion with Alu I. The alleres with the restriction site and the non cleavable alleres were designated $A_1$ and $A_2$. In conclusion, genotype $A_1A_2$ and exercise are increased and associated with plasma fibrinogen levels. But, there were no significant differences by smoking, gender, age, drinking and cholesterol.

• Toxicological Research
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• 제29권3호
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• pp.157-164
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• 2013

Although stroke is one of the leading causes of death and disability worldwide, preventive or therapeutic options are still limited. Therefore, a better understanding of the pathophysiological characteristics of this life-threatening disease is urgently needed. The incidence and prevalence of ischemic stroke are increased by exposure to certain types of xenobiotics, including heavy metals, suggesting the possible toxicological contribution of these compounds to the onset or aggravation of stroke. Among the potential targets, we have focused on alterations to cerebral endothelial cells (CECs), which play important roles in maintaining the functional integrity of brain tissue.

• Natural Product Sciences
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• 제1권1호
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• pp.25-30
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• 1995

Pharmacognostic study was carried out on the seeds of Trigonella foenumgraecum L. (fenugreek) in order to establish its pharmacognostic characteristics. In view of its renewed interest as a dietary supplement among the local inhabitants afflicted with diabetes, its hypoglycaemic activity in normal as well as diabetic rats was also investigated. Oral glucose tolerance test showed that a suspension of the powdered trigonella seed inhibited the increase in blood glucose levels in normal rats that had been treated with an oral glucose load prior to the test. A reduction in the blood glucose levels was also observed when a suspension of the powdered seed was given by gastric intubation to the streptozotocin-induced diabetic rats. These findings suggested that trigonella seeds possessed some hypoglycaemic activities that might be useful to the diabetics.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 춘계학술대회 논문집
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• pp.124-127
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• 2002

Ceil embolisation technique has been used to treat the intracranial aneurysms. Microcoils inserted into the aneurysm sac induce the blood flow stagnation inside the aneurysm sac, which causes the thrombus formation and embolisation of aneurysm. Since the intraaneurysmal flow patterns affect the embolisation process, we want to measure the flow field for different locations of coil inside the aneurysm sac . Lateral aneurysm models are manufactured using rapid prototyping, and the velocity fields are measured using particle image velocitimeter. Distally blocked models showed less flow into the aneurysm sac comparing to proximally blocked models. Also blocking the neck of aneurysm showed better inflow blocking comparing to blocking the dome of aneurysm. These results suggest that distal neck should be the preferred locations of coil for aneurysm embolisation.