• The Journal of the Society of Stroke on Korean Medicine
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• v.6 no.1
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• pp.9-16
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• 2005

Objective : The heart rate variability is very useful indicator to study the function of the autonomic nervous system(ANS), and the physiologic signals can be observed based on the changes of the ANS of the heart. In order to assay the effects of the laser exposing to healthy subjects, the double blind test has been performed. Methods : This study included 62 healthy adults who have not any ANS disease and had normal sinus rhythm in electrocardiogram. The control group consisted of 31 subjects, laser group consisted of 31 subject. HRV was measured for 5 minutes before laser irradiation, sham and real laser irradiated for 30 minutes and than HRV remeasured for 5 minutes. Statistical significance was evaluated by independent T-test. Results : Mean HRV, Ln(VLF), Ln(HF), Ln(TP) of both groups at post-laser period decreased compared with that of the pre-laser period. Ln(LF) of both groups at post-laser period increased compared with that of the pre-laser period. LF/HF, SDNN of real laser group decreased and sham group decreased. Conclusions : There is no difference between two groups. The reason is presumed that all the studied subjects are healthy adults, and also the short and single transcutaneous laser irradiation would not influence upon changes of the ANS. The further study must be followed.

• Restorative Dentistry and Endodontics
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• v.46 no.1
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• pp.9.1-9.9
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• 2021

Objectives: This randomized clinical trial aimed to assess the effectiveness of buccal infiltration with piroxicam on the anesthetic efficacy of inferior alveolar nerve block (IANB) with buccal infiltration in irreversible pulpitis, with pain assessed using the Heft-Parker visual analogue scale (HP-VAS). Materials and Methods: This study included 56 patients with irreversible pulpitis in mandibular molars, randomly distributed between 2 groups (n = 28). After evaluating the initial pain score with the HP-VAS, each patient received IANB followed by buccal infiltration of 2% lignocaine with adrenaline (1:80,000). Five minutes later, the patients in groups 1 and 2 were given buccal infiltration with 40 mg/2 mL of piroxicam or normal saline, respectively. An access opening procedure (AOP) was performed 15 minutes post-IANB once the individual showed signs of lip numbness as well as 2 negative responses to electric pulp testing. The HP-VAS was used to grade the patient's pain during caries removal (CR), AOP, and working length measurement (WLM). Successful anesthesia was identified either by the absence of pain or slight pain through CR, AOP, and WLM, with no requirement of a further anesthetic dose. A statistical analysis was done using the Shapiro-Wilk and Mann-Whitney U tests. Results: The piroxicam group presented a significantly lower (p < 0.05) mean pain score than the saline group during AOP. Conclusions: Buccal infiltration with piroxicam enhanced the efficacy of anesthesia with IANB and buccal infiltration with lignocaine in patients with irreversible pulpitis.

• Annual Conference on Human and Language Technology
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• 2019.10a
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• pp.213-218
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• 2019

기계독해는 자연어로 표현된 질문과 단락이 주어졌을 때, 해당 단락 내에 표현된 정답을 찾는 태스크이다. 최근 기계독해 태스크도 다른 자연어처리 태스크와 유사하게 BERT, XLNet, RoBERTa와 같이 사전에 학습한 언어모델을 이용하고 질문과 단락이 입력되었을 경우 정답의 경계를 추가 학습(fine-tuning)하는 방법이 우수한 성능을 보이고 있으며, 특히 KorQuAD v1.0 데이터셋에서 학습 및 평가하였을 경우 94% F1 이상의 높은 성능을 보이고 있다. 본 논문에서는 현재 최고 수준의 기계독해 기술이 학습셋과 유사한 평가셋이 아닌 일반적인 질문과 단락 쌍에 대해서 가지는 일반화 능력을 평가하고자 한다. 이를 위하여 첫번째로 한국어에 대해서 공개된 KorQuAD v1.0 데이터셋과 NIA v2017 데이터셋, 그리고 엑소브레인 과제에서 구축한 엑소브레인 v2018 데이터셋을 이용하여 데이터셋 간의 교차 평가를 수행하였다. 교차 평가결과, 각 데이터셋의 정답의 길이, 질문과 단락 사이의 오버랩 비율과 같은 데이터셋 통계와 일반화 성능이 서로 관련이 있음을 확인하였다. 다음으로 KorBERT 사전 학습 언어모델과 학습 가능한 기계독해 데이터 셋 21만 건 전체를 이용하여 학습한 기계독해 모델에 대해 블라인드 평가셋 평가를 수행하였다. 블라인드 평가로 일반분야에서 학습한 기계독해 모델의 법률분야 평가셋에서의 일반화 성능을 평가하고, 정답 단락을 읽고 질문을 생성하지 않고 질문을 먼저 생성한 후 정답 단락을 검색한 평가셋에서의 기계독해 성능을 평가하였다. 블라인드 평가 결과, 사전 학습 언어 모델을 사용하지 않은 기계독해 모델 대비 사전 학습 언어 모델을 사용하는 모델이 큰 폭의 일반화 성능을 보였으나, 정답의 길이가 길고 질문과 단락 사이 어휘 오버랩 비율이 낮은 평가셋에서는 아직 80%이하의 성능을 보임을 확인하였다. 본 논문의 실험 결과 기계 독해 태스크는 특성 상 질문과 정답 사이의 어휘 오버랩 및 정답의 길이에 따라 난이도 및 일반화 성능 차이가 발생함을 확인하였고, 일반적인 질문과 단락을 대상으로 하는 기계독해 모델 개발을 위해서는 다양한 유형의 평가셋에서 일반화 평가가 필요함을 확인하였다.

• Annual Conference of KIPS
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• 2021.11a
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• pp.1290-1293
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• 2021

Currently, blind people are experiencing a lot of inconvenience in their daily lives. In order to provide helpful service for the visually impaired, this study was carried out to make a new smart glasses that transmit information monitoring walking environment in real-time object recognition. In terms of object recognition, YOLOv4 was used as the artificial intelligence model. The objects, that should be identified during walking of the visually impaired, were selected, and the learning data was populated from them and re-learning of YOLOv4 was performed. As a result, the accuracy was average of 68% for all objects, but for essential objects (Person, Bus, Car, Traffic_light, Bicycle, Motorcycle) was measured to be 84%. In the future, it is necessary to secure the learning data in more various ways and conduct CNN learning with various parameters using darkflow rather than YOLOv4 to perform comparisons in the various ways.

• Analytical Science and Technology
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• v.20 no.1
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• pp.78-83
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• 2007

To perform proficiency test for determining anti-impotence drug-like compounds in food, interlaboratory test has been done. Targets were 6 such as sildenafil, tadalafil, vardenafil, homosildenafil, hydroxy-homosildenafil and pseudo-vardenafilI. Total 13 institutes were participated and all is in charging of food analysis. To do double blind test, the reference materials were made as 13 different ginseng drink samples and each sample had random 3 targets. By the official method for anti-impotence drug-like compounds in food code, sample was just diluted in water, extracted in organic solvents, determined by HPLC/UV and then confirmed by LC/MS. The analytical duration was 60 days after receiving sample. Ten out of 13 institutes were satisfied by evaluation of Z-score and RSZ according to the regulation for managing analytical quality assurance.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.48 no.1
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• pp.21-32
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• 2022

Objectives: Inferior alveolar nerve block (IANB) is commonly used for mandibular dentoalveolar surgery. The objective of this study was to evaluate and compare the effectiveness of coadministration of dexamethasone (4 mg/mL) or adrenaline (0.01 mg/mL) as an adjuvant with lignocaine 2% in IANB during third molar surgery (TMS). Patients and Methods: This double-blind, randomized controlled trial was conducted between March and August 2020. The investigators screened patients needing elective TMS under local anesthesia. Based on strict inclusion and exclusion criteria, patients were enrolled in this study. These patients were assigned randomly into two study groups: dexamethasone group (DXN) or adrenaline group (ADN). Outcome variables were postoperative edema, trismus, visual analogue scale (VAS), perioperative analgesia, onset time, and duration of IANB. Results: Eighty-three patients were enrolled in this study, of whom 23 (27.7%) were eliminated or excluded during follow-up. This study thus included data from 60 samples. Mean age was 32.28±11.74 years, including 28 females (46.7%) in the ADN (16 patients, 57.1%) and DXN (12 patients, 42.9%) groups. The duration of action for DXN (mean±standard deviation [SD], 4:02:07±0:34:01 hours; standard error [SE], 0:06:00 hours; log-rank P=0.001) and for ADN (mean±SD, 1:58:34±0:24:52 hours; SE, 0:04:42 hours; log-rank P=0.001) were found. Similarly, time at which 1st analgesic consume and total number of nonsteroidal antiinflammatory drugs need to rescue postoperative analgesia was found statistically significant between study groups (t (58)=-11.95; confidence interval, -2:25:41 to -1:43:53; P=0.001). Early-hours VAS was also significantly different between the study groups. Conclusion: A single injection of dexamethasone prolongs the duration of action of lignocaine 2% IANB. Additionally, it can be used in cases where adrenaline is contraindicated.

• Journal of Acupuncture Research
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• v.39 no.2
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• pp.115-121
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• 2022

Background: To evaluate the efficacy and safety of Phellinus linteus (PL) extract for the treatment of knee osteoarthritis (KOA) a pilot clinical study was performed. Methods: There were 24 patients with KOA who enrolled in this double-blind, randomized, controlled, clinical trial. There were 3 groups: PL 1,000 mg/day (PL 1,000), PL 1,500 mg/day (PL 1,500), and dextrin 3,000 mg/day (placebo). Patients took capsules twice a day, 3 capsules at a time, over 8 weeks. Patients were monitored prior to treatment (Visit 1: Week 0), and followed up every 4 weeks (Visit 2: Week 4 and Visit 3: Week 8) where outcome measurements were taken. The primary outcome measure was the score from the Korean version of the Western Ontario and McMasters Universities from baseline to Week 8. The secondary outcomes were measurements from the visual analog scale, quality of life scale, erythrocyte sedimentation, and c-reactive protein. Adverse events were recorded at every visit. Results: The Korean version of the Western Ontario and McMasters Universities score showed the greatest improvement in symptoms of KOA in the PL 1,500 group compared with the placebo group. The erythrocyte sedimentation tended to decrease in the PL 1,500 group compared with the placebo group (which was within the normal range). The visual analog scale score decreased in all groups, with no significant differences between groups. No adverse events related to PL were reported. There were no abnormal hematological or physical findings. Conclusion: This pilot clinical trial was the first step to assess the efficacy and safety of PL used in the treatment of patients with KOA.

• Journal of the Korean Society of Food Culture
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• v.23 no.3
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• pp.403-409
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• 2008

Recently, the desire for low body weight, which is an abnormal weight construct along with obesity, has become an evident and serious problem in teenagers. In Korea, the desire for low weight is not perceived as an important problem, but it is rapidly expanding relative to the physical changes and developmental issues teenagers experience. The social atmosphere presented through mass media is the key influencer for the increasing low weight occurrence in teenagers. Because thoughts about beauty have changed among people, and since there is apparent blind interest in slim body shape and appearance, already low-weight individuals are attempting to lose weight along with obese persons. Thus, we consider it necessary to guide teenagers toward having correct perceptions with regard to weight and their own body shape, and that a healthy and appropriate weight is beautiful. Therefore, for this study, we investigated body perception, abnormal weight, attitude toward weight control, and factors related to eating behavior among teenage girls, who are considered the at risk group for overt body weight control behavior. Based on this, we have attempted to set in motion a systematic and active nutrition education program that will allow us to increase body satisfaction by educating on nutritional issues related to development, and ultimately, implant healthy body shape perceptions.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.2B
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• pp.131-137
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• 2006

We have investigated the properties of the Singular Spectrum Analysis (SSA) coupled with the Linear Recurrent Formula which made it possible to complement the parametric time series model. The SSA has been applied to extract the underlying properties of the principal component of hydrologic time series, which can often be identified as trends, seasonalities and other oscillatory series, or noise components. Generally, the prediction by the SSA method can be applied to hydrologic time series governed (may be approximately) by the linear recurrent formulae. This study has examined the forecasting ability of the SSA-LRF model. These methods were applied to monthly discharge and water surface level data. These models indicated that two of the time series have good abilities of forecasting, particularly showing promising results during the period of one year. Thus, the method presented in this study suggests a competitive methodology for the forecast of hydrologic time series.

• Journal of the Korean Society of Food Culture
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• v.23 no.1
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• pp.68-72
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• 2008

This study demonstrated the effects of extracts from the mushroom Keumsa sangwhang(Phellinus linteus) (KPLE) on fasting glucose and cholesterol levels in human blood. In this double-blind, placebo-controlled human intervention study, healthy volunteers were randomized to receive 3.3 g of KPLE (n=31) or placebo (n=31) per day by oral administration for 8 weeks. The cholesterol and fasting serum glucose levels were evaluated before and after treatment. The fasting serum glucose level was significantly decreased by KPLE administration (p<0.01), but the total cholesterol, triglyceride, HDLcholesterol and LDL-cholesterol concentrations did not change. This study suggests a possibility that KPLE may be useful as a functional food for the prevention of diabetes mellitus.