• 제목/요약/키워드: Bipolar

검색결과 1,564건 처리시간 0.03초

양극성 장애에서의 수면장애: 일주기 리듬의 교란과 수면 무호흡증을 중심으로 (Sleep Disorders in Bipolar Disorders: A Narrative Review on Circadian Rhythm Disturbances and Sleep Apnoea)

  • 이준희;오상훈
    • 수면정신생리
    • /
    • 제29권2호
    • /
    • pp.40-44
    • /
    • 2022
  • Bipolar disorders are a group of mood disorders characterised by relapsing mood episodes throughout the course of illness. Patients with bipolar disorders commonly present with various sleep problems. Patients in a manic episode generally show decreased need of sleep and those in a depressed episode frequently complain about hypersomnia. Current literature even points to evidence that patients with bipolar disorder in euthymic state may still show signs of sleep disturbances when compared to the general population. Clinicians may also note intricate interactions between changes of circadian rhythm and evolution of mood episodes in patients with bipolar disorder. Also, commonly prescribed medications which plays a crucial role in treatment of bipolar disorders including mood stabilisers and antipsychotic medications often cause significant weight gain over time. Being a risk factor of sleep apnoea, weight gain can predispose the patient to develop sleep apnoea. In this narrative review, we summarised current evidence and literature regarding characteristics of circadian rhythm and comorbid sleep apnoea in patients with bipolar disorder. We also present literature regarding implications of circadian disturbance and comorbid sleep apnoea in managing patients with bipolar disorder.

제1형 양극성 장애와 Lymphotoxin Alpha 유전자 단일염기 다형성 연관 연구 (Association Study of Single-Nucleotide Polymorphism in Lymphotoxin Alpha Gene and Bipolar I Disorder)

  • 김상하;전태연
    • 생물정신의학
    • /
    • 제19권3호
    • /
    • pp.134-139
    • /
    • 2012
  • Objectives : Proinflammatory process has been implicated as an underlying mechanism of bipolar disorder and schizophrenia. Previous studies have suggested a possible role of lymphotoxin alpha (LTA) gene in the development of schizophrenia and have prompted further investigation in bipolar patients. Association of the LTA +252A/G polymorphism with susceptibility to bipolar I disorder itself as well as with vulnerability among a subset of psychotic bipolar patients were tested. Methods : DNA extraction was done by a standard method and genotyping was carried out by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method in 114 Korean patients with bipolar I disorder and 202 healthy controls. SPSS v18.0 was used for statistical analysis. Comparisons of the genotype and allele distributions in LTA +252A/G polymorphism were made using a chi-square test. The genotype and allele associations were also evaluated using odds ratio (OR) and 95% confidence interval (CI). Statistical significance was accepted when p was < 0.05. Results : No significant association was found between the LTA +252A/G polymorphism and bipolar disorder. However, LTA +252G allele was present with significantly higher frequency among bipolar patients with psychotic features compared to those without (${\chi}^2$ = 4.69, p = 0.034, OR = 2.495, 95% CI = 1.069-5.827). Conclusion : The results suggest that the allele LTA +252G of the polymorphism may be associated with the psychotic subset of bipolar disorder but not with bipolar I disorder itself. Adequately powered subsequent studies should be conducted.

Development of Carbon Composite Bipolar Plates for Vanadium Redox Flow Batteries

  • Lee, Nam Jin;Lee, Seung-Wook;Kim, Ki Jae;Kim, Jae-Hun;Park, Min-Sik;Jeong, Goojin;Kim, Young-Jun;Byun, Dongjin
    • Bulletin of the Korean Chemical Society
    • /
    • 제33권11호
    • /
    • pp.3589-3592
    • /
    • 2012
  • Carbon composite bipolar plates with various carbon black contents were prepared by a compression molding method. The electrical conductivity and electrochemical stability of the bipolar plates have been evaluated. It is found that the electrical conductivity increases with increasing carbon black contents up to 15 wt %. When the carbon black contents are greater than 15 wt %, the electrical conductivity decreases because of a poor compatibility between epoxy resin and carbon black, and a weakening of compaction in the carbon composite bipolar plate. Based on the results, it could be concluded that there are optimum carbon black contents when preparing the carbon composite bipolar plate. Corrosion tests show that the carbon composite bipolar plate with 15 wt % carbon black exhibits better electrochemical stability than a graphite bipolar plate under a highly acidic condition. When the optimized carbon composite bipolar plate is applied to vanadium redox flow cells, the performance of flow cells with the carbon composite bipolar plate is comparable to that of flow cells with the graphite bipolar plate.

고속 Bipolar 소자를 이용한 comparator 설계 (Comparator design using high speed Bipolar device)

  • 박진우;조정호;구용서;안철
    • 대한전자공학회:학술대회논문집
    • /
    • 대한전자공학회 2004년도 하계종합학술대회 논문집(2)
    • /
    • pp.351-354
    • /
    • 2004
  • This thesis presents Bipolar transistor with SAVEN(Self-Aligned VErtical Nitride) structure as a high-speed device which is essential for high-speed system such as optical storage system or mobile communication system, and proposes 0.8${\mu}m$ BiCMOS Process which integrates LDD nMOS, LDD pMOS and SAVEN bipolar transistor into one-chip. The SPICE parameters of LDD nMOS, LDD pMOS and SAVEN Bipolar transistor are extracted, and comparator operating at 500MHz sampling frequency is designed with them. The small Parasitic capacitances of SAVEN bipolar transistor have a direct effect on decreasing recovery time and regeneration time, which is helpful to improve the speed of the comparator. Therefore the SAVEN bipolar transistor with high cutoff frequency is expected to be used in high-speed system.

  • PDF

연료전지 차량용 금속분리판 개발 (Development of Metaal Bipolar plates for Fuel Cell Vehicles)

  • 진상문;양유창;김세훈
    • 한국신재생에너지학회:학술대회논문집
    • /
    • 한국신재생에너지학회 2009년도 춘계학술대회 논문집
    • /
    • pp.331-334
    • /
    • 2009
  • Currently, the bipolar plates are fabricated mainly from graphite materials. However, metal bipolar plate are getting most attractive due to their good feasibility of mass production and low cost. In this study, metal bipolar plates for fuel cell Vehicles were developed with a concept based on the straight flow patterns to minimize the pressure drop and spring back. And molded gasket apply to the bipolar plate for improve sealing performance. Results show that the metal bipolar plate have a high potential to replace for graphite materials in fuel cell application.

  • PDF

Studies on the Forming Process for the Bipolar Plate of Fuel Cells

  • Jin, Chul-Kyu;Lee, Jun-Kyoung
    • 한국산업융합학회 논문집
    • /
    • 제21권4호
    • /
    • pp.175-181
    • /
    • 2018
  • Stamping process and rubber pad forming process were performed to manufacture the bipolar plate for fuel cells. For that, a vacuum die casting process and a semi-solid forming process wherein liquid-state materials were used were adopted. After preparing the blank with the stainless steel thin plate having a thickness of 0.1 mm, the bipolar plate channel was formed with the stamping process and rubber pad forming process. The depth of the bipolar plate channel prepared by the stamping method was 0.45 mm and the depth of the bipolar plate channel prepared by the rubber pad forming process was 0.41 mm. Meanwhile, with the vacuum die casting and semi solid forming, the bipolar plate having a channel depth of 0.3 mm, same as the size of the die, could be formed.

의류소재의 태 평가에 사용되는 대립어 척도와 부정어 척도 비교 (Evaluation of Subjective Fabric Hand: Comparing Bipolar Adjectives with Unipolar Adjectives)

  • 김의경;이미식
    • 한국의류학회지
    • /
    • 제28권2호
    • /
    • pp.235-242
    • /
    • 2004
  • The purpose of this study was to develop a scale for the evaluation of the subjective fabric hand. In order to find out the appropriate method for the evaluation, bipolar adjectives were compared to unipolar adjectives. One hundred female university students we.e selected as judges. They assessed 9 fabrics using the 9 point scale system for both bipolar and unipolar adjectives. When using the bipola. scale, judges responded more consistently showing smaller deviation among their responses. The Judges seemed to understand the meanings of adjectives in the bipolar scale more clearly than in the unipolar scale. Unipolar scale has twice the number of questions than bipolar scale does. Therefore. judges often felt bored responding to the questions using unipolar adjectives. If the appropriate antonym can be found through verified method, bipolar scale seems to have more advantages than unipolar scale.

ON BIPOLAR M - N-MULTI Q-FUZZY SUBGROUPS

  • MOURAD OQLA MASSA'DEH;AHLAM FALLATAH
    • Journal of applied mathematics & informatics
    • /
    • 제41권4호
    • /
    • pp.781-799
    • /
    • 2023
  • For any bipolar multi Q-fuzzy set δ of an universe set G, we redefined a normal, conjugate concepts, union and product operations of a bipolar M - N-multi Q-fuzzy subgroups and we discuss some of its properties. On the other hand, we introduce and define the level subsets positive β-cut and negative α-cut of bipolar M - N- multi Q- fuzzy subgroup and discuss some of its related properties.

Bipolar Membranes and Their Applications

  • Strathmann, H.
    • 멤브레인
    • /
    • 제11권3호
    • /
    • pp.97-108
    • /
    • 2001
  • Bipolar membranes have gained increasing interest as a tool for an efficient production of acids and bases from the corresponding salts. A large number of potential applications have been identified in the chemical and biochemical industry have been identified and evaluated on a laboratory scale. In spite of extensive research efforts and laboratory and pilot plat test, there are hardly any large-scale commercial plants. In this paper the basic concept of the electrodialytic water dissociation with bipolar membranes are briefly reviewed. The limitations of today\`s bipolar membranes are indicated. Selected examples of successful applications of the bipolar membrane technology are discussed.

  • PDF