• Title/Summary/Keyword: Bioresource

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Neuraminidase Inhibitors from the Culture Broth of Phellinus linteus

  • Yeom, Ji-Hee;Lee, In-Kyoung;Ki, Dae-Won;Lee, Myeong-Seok;Seok, Soon-Ja;Yun, Bong-Sik
    • Mycobiology
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    • v.40 no.2
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    • pp.142-144
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    • 2012
  • During the search for neuraminidase inhibitors from medicinal fungi, we found that the culture broth of Phellinus linteus exhibited potent inhibitory activity. Solvent partition, Sephadex LH-20 column chromatography, and high-performance liquid chromatography (HPLC) were performed for purification of two active substances from the culture broth. According to $^1H$ NMR measurements and comparison of HPLC retention times with those of authentic compounds, their chemical structures were identified as hispidin and hypholomine B. Compounds (hispidin) 1 and 2 (hypholomine B) inhibited neuraminidase, with $IC_{50}$ values of 13.1 and 0.03 ${\mu}M$, respectively.

The pharmacological effect of the methanol extracts from Acanthopanax senticosus after immobilized and chronic swimming stresses in rats

  • Park, Hee-Dong;Kim, Yu-Ji;Yang, You-Jong;Lee, Jae-Joon;Lee, Jung-Joon;Lee, Myung-Koo
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.264.2-265
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    • 2002
  • Acanthopanax senticosus has been used clinically as tonic. anti-rheumatic and prophylactic purpose for chronic bronchitis. hypertension. ischemic heart disease. and gastric ulcer. We investigated the effects of methanol extracts from Acanthopanax senticosus (KS. KR. MS, MR, HS. HR, SS and SR) on catecholamine and cortisol content of serum after immobilization and on the exercise time to exhaustion in chronic swimming stressed rats. (omitted)

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A New Record of Volutella ciliata Isolated from Crop Field Soil in Korea

  • Babu, Anam Giridhar;Kim, Sang Woo;Yadav, Dil Raj;Adhikari, Mahesh;Kim, Changmu;Lee, Hyang Burm;Lee, Youn Su
    • Mycobiology
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    • v.43 no.1
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    • pp.71-74
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    • 2015
  • During a survey of fungal species in South Korea, a species of Volutella ciliata was isolated and described based on the analysis of the internal transcribed spacer region of its rDNA and its morphological characteristics. This is the first record of Volutella ciliata isolated from crop field soil in Korea.

A New Report on Oidiodendron flavum Isolated from Field Soil in Korea

  • Adhikari, Mahesh;Kim, Sangwoo;Yadav, Dil Raj;Babu, Anam Giridhar;Kim, Changmu;Lee, Hyang Burm;Lee, Youn Su
    • The Korean Journal of Mycology
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    • v.42 no.3
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    • pp.235-238
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    • 2014
  • Oidiodendron flavum KNU13-6 was isolated for the first time from field soil in Korea and identified based on the internal transcribed spacer region (ITS) of rDNA and morphological characteristics. Based on phylogenetic analysis of ITS and morphological characteristics, the species has not been previously reported in Korea.

A New Record of Pseudallescheria boydii Isolated from Crop Field Soil in Korea

  • Babu, A. Giridhar;Kim, Sang Woo;Yadhav, Dil Raj;Adhikari, Mahesh;Kim, Changmu;Lee, Hyang Burm;Lee, Youn Su
    • Mycobiology
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    • v.42 no.4
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    • pp.397-400
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    • 2014
  • Pseudallescheria boydii KNU13-2 was isolated from crop field soil and identified by analysis of internal transcribed spacer regions of rDNA and morphological characteristics. In the literature, P. boydii has been mentioned as a human pathogen. This is the first record of P. boydii isolated from crop field soil in Korea.

Optimized Substrate Concentrations for Production of Long-Chain Isomaltooligosaccharides Using Dextransucrase of Leuconostoc mesenteroides B-512F

  • Lee, Min-Sung;Cho, Seung-Kee;Eom, Hyun-Ju;Kim, So-Young;Kim, Tae-Jip;Han, Nam-Soo
    • Journal of Microbiology and Biotechnology
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    • v.18 no.6
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    • pp.1141-1145
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    • 2008
  • Isomaltooligosaccharide (IMO) is a promising dietary component with prebiotic effect, and the long-chain IMOs are preferred to short chain ones owing to the longer persistence in the colon. To establish the optimal process for synthesis of long-chain IMOs, we systematically examined the reaction condition of dextransucrase of Leuconostoc mesenteroides B-512F by changing the ratio of sucrose to maltose (varying as 1:4, 1:2, 1:1, and 2:1) and amount of each sugar (from 2% to 20%). As a result, a ratio of 2:1 (sucrose to maltose, 10:5% or 20:10%, w/v) was determined as an optimal condition for long-chain IMO synthesis (DP3-DP9) with relatively higher yields (70-90%, respectively).