• 제목/요약/키워드: Biomedical polymer

검색결과 318건 처리시간 0.029초

Hierarchical porous carbon nanofibers via electrospinning

  • Raza, Aikifa;Wang, Jiaqi;Yang, Shan;Si, Yang;Ding, Bin
    • Carbon letters
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    • 제15권1호
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    • pp.1-14
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    • 2014
  • Carbon nanofibers (CNFs) with diameters in the submicron and nanometer range exhibit high specific surface area, hierarchically porous structure, flexibility, and super strength which allow them to be used in the electrode materials of energy storage devices, and as hybrid-type filler in carbon fiber reinforced plastics and bone tissue scaffold. Unlike catalytic synthesis and other methods, electrospinning of various polymeric precursors followed by stabilization and carbonization has become a straightforward and convenient way to fabricate continuous CNFs. This paper is a comprehensive and brief review on the latest advances made in the development of electrospun CNFs with major focus on the promising applications accomplished by appropriately regulating the microstructural, mechanical, and electrical properties of as-spun CNFs. Additionally, the article describes the various strategies to make a variety of carbon CNFs for energy conversion and storage, catalysis, sensor, adsorption/separation, and biomedical applications. It is envisioned that electrospun CNFs will be the key materials of green science and technology through close collaborations with carbon fibers and carbon nanotubes.

전기방사를 이용한 조직공학용 실크 피브로인 나노 섬유 지지체의 기공 크기 조절 (Controlling Pore Size of Electrospun Silk Fibroin Scaffold for Tissue Engineering)

  • 조세연;박현호;진형준
    • 폴리머
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    • 제36권5호
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    • pp.651-655
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    • 2012
  • 인체의 여러 조직 및 장기를 재생하고자 하는 조직공학에 있어 중요한 요소 중의 하나인 지지체는 세포외기질을 모방한 것으로 손상된 조직을 재생하는데 있어 기본 형틀의 역할을 수행하며, 세포의 분화와 성장 그리고 영양분과 산소의 원활한 공급을 위한 상호 연결된 다공성 구조가 필요하다. 본 연구에서는 실크 피브로인의 조직공학용 지지체로의 응용가능성 향상을 위하여 폴리에틸렌옥사이드를 사용한 보다 넓은 기공과 다공의 연결성을 가지는 실크 피브로인 나노 섬유 지지체를 제조하였다.

세포적합성 고분자 표면에 관한 연구 II. 표면 개질된 고분자에의 세포 배양 (Polymer Surfaces for Cell Adhesion II. Cell Culture on Surface-modified Polymers)

  • 이진호;강길선
    • 대한의용생체공학회:의공학회지
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    • 제10권2호
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    • pp.195-202
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    • 1989
  • Chinese Hamster Ovary( CHO) cells were cultured on the surface-modified polymers described in the previous study( "Polymer Surfaces for Cell Adhesion. 1. Surface Modification of Polymers and ESCA Analysis, " J. of KOSOMBE, Vol. 10, No. 1, 43-51, 1989). Among the physicochemical treatment methods. the chloric acid treatment was found to be the best method of rendering the polymer surfaces adhesive for CHO cells probably due to the high density of hydroxyl groups on the surface. Among the biological methods, the fibronectin treatment was best for CHO cell-compatibility probably due to specific active sites existed on the tell-binding domains of the fibronectin structure. When we compare the cell-compatibility of the chloric acid - and the fibronectin -treated PET surfaces, the number of cells attached on the surfaces were increased by 460.5 % and 559.0 % and, respectively, after 32 hr CHO cell culture, compared to that of untreated PET.eated PET.

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Polyoxyethylene Alkylether Sulfate 계면활성제를 사용한 무기/유기 코어-셀의 합성 (Synthesis of Inorganic/Organic Core-Shell Polymer Using Polyoxyethylene Alkylether Sulfate as a Surfactant)

  • 김덕술;박근호
    • 한국응용과학기술학회지
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    • 제27권1호
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    • pp.93-97
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    • 2010
  • Silicone dioxide absorbed polyoxyethylene alkylether sulfate (EU-S75D) surfactant was prepared. The core-shell composite of inorganic/organic were polymerized by using styrene(St) as a shell monomer and potassium persulfate(KPS) as an initiator. We studied the effect of surfactants on the core-shell structure of silicone dioxide/styrene in the presence of an anionic surfactant lauryl sulfate(SLS). The structure of core-shell polymer were investigated by measuring to the thermal decomposition of polymer composite using thermogravimetric analyzer(TGA) and morphology of latex by scanning electron microscope(SEM).

생체적합성과 생분해성을 갖는 Polypeptide Copolymer의 합성과 물성에 관한 연구(II) (Synthesis and Physical Properties of Biocompatible and Biodegradable Polypeptide Copolymers(II))

  • 강인규;권대룡
    • 대한의용생체공학회:의공학회지
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    • 제10권3호
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    • pp.237-242
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    • 1989
  • The physical properties and drug release behaviours of polyethylene glycol grafted poly ${\gamma}$- benzyl L-glutamate (PEG- g- PBLG), polyethylene glycol crosslinked poly ${\gamma}$-benzyl L- glutamate(PEG-c-PBLG), and PBLG homopolymer are compared. PBLG containing PEG segements showed higher wettability and larger enlongation than PBLG homoplymer, but lower elastic modulus. The release rate of rhodamine is strongly influenced by the wettability of the polymer. Rhodamine is more rapidly released from PEG-c-PBLG membrane having a larger water contact angle than from other polymer having a lower water contact angle. The surfaces of PBLG derivative membranes are modified by substitution reaction using hydroxyalkylamine. The resulting polymer membranes showed hider wettability and swelling ratio than virgin membranes.

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표면개질에 의한 혈액적합성 폴리우레탄의 제조 (Preparation of blood-compatible polyurethanes by surface modification)

  • 한동근;정서영;김영하;민병구
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1990년도 추계학술대회
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    • pp.61-63
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    • 1990
  • To develop better blood compatibility of commercial polyurethane(PU), PU surface was chemically modified wi th a hydrophobic perfluorocarhon or a hydrophilic polyethylene oxide(PEO) and/or sulfonated groups, respectively. The water contact angle of modified PUs varied from $110^{\circ}$ to $0^{\circ}$. All the modified PUs were more blood compatible than untreated PU. In particular, PEO-sulfonate grafted PUs showed a very enhanced antithrombogenicity due to the synergistic effect of PEO and $SO_3$ groups. Therefore more hydrophobic and hydrophilic PU surfaces are promising for improving the blood compatibility.

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Synthesis of Quantum Dot-Tagged Submicrometer Polystyrene Particles by Miniemulsion Polymerization

  • Joumaa, Nancy;Lansalot, M.;Theretz, A.;Elaissari, A.;Sukhanova, A.;Artemyev, M.;Nabiev, I.;Cohen, J.H.M.
    • 한국고분자학회:학술대회논문집
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    • 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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    • pp.330-330
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    • 2006
  • The elaboration of fluorescent submicronic polymer particles exhibiting narrow particle size distribution as well as good photostability is of particular interest in various biomedical applications. In the frame of this work, labeled polystyrene latexes have been synthesized by miniemulsion polymerization using luminescent semiconductor nanoparticles (quantum dots, QD). The influence of incorporation of QDs on the polymerization kinetics as well as on the optical properties of the obtained latexes will be discussed.

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1-3형 압전복합재료의 제조 및 펄스응답특성 (Pulse response characteristics and preparation of piezoelectic composite materials with 1-3 connectivity)

  • 김진수;김용혁;김호기;이덕출
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 1989년도 춘계학술대회 논문집
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    • pp.77-80
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    • 1989
  • The aim of the study is to develope the processing technique of PZT-Polymer piezoelectric composite materials for ultrasonic transducer application such as biomedical probe and hydrophone. Piezoelectric composite of PZT and polymer with 1-3 connectivity patterns have been fabricated by dicing-filling method and extrusion forming method. In this study processing forming method. In the study processing steps by extrusion forming method in the preperation of PZT/polymer piezoelectric composites are described. The PZT powder used in the study is commercial powder which is prepared by mixing PbO, TiO$_2$ and ZrO$_2$. The binder, water and plasticizer are mixed with the PZT powder to form a slip. It is necessary to adjust the viescosity of slip according on the PZT rod diameters to be extruded. The electromechanical properties of the piezoelectric composites are characterized in terms of the thickness resonance mode. The pulse response characteristics by the ultrasonic transducer analyzer and osciloscope are evaluated.

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고분자간전해질복합체로 된 hydrogel의 형성과 약의 방출성질 (Formation of Polyelectrolyte Complex Hydrogel and its Application to Drug Delivery System)

  • 조종수;김성웅;김학주
    • 대한의용생체공학회:의공학회지
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    • 제9권1호
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    • pp.73-78
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    • 1988
  • The polymer electrolyte complex hydrogels consisting of poly (methacrylic acid) and poly (4-vinylpyrridine) were formed and 5-flurouracil and pilocarpine drugs were loaded on their hydrogels. Cumulative 5-FU released from PEC hydrogel was affected by the degree of loading and release rate of 5-FU was followed by the monolithic type. Cumulative pilocarpine released from PEC hydrogel increased by ionic interaction between cationic pilocarpine and anionic PMA. Release rate showed the zero order after burst effect.

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