• 대한전기학회:학술대회논문집
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• 대한전기학회 1995년도 추계학술대회 논문집 학회본부
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• pp.157-160
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• 1995

Neural networks potentially offer a general framework for modeling and control of nonlinear systems. The conventional neural network models are a parody of biological neural structures, and have very slow learning. In order to emulate some, dynamic functions, such as learning and adaption, and to better reflect the dynamics of biological neurons, M.M.Gupta and D.H.Rao have developed a 'dynamic neural model'(DNU). Proposed neural unit model is to introduce some dynamics to the neuron transfer function, such that the neuron activity depends on internal states. Numerical examples are presented for a model system. Those case studies showed that the proposed DNU is so useful in practical sense.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2008년도 추계학술대회A
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• pp.1446-1449
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• 2008

Immune system is composed of multiple cells with distinct functions, and immune responses are orchestrated by complex and dynamic cell-cell interactions. Therefore, each cell behavior and function should be understood under right spatio-temporal context. Studying such complexity and dynamics has been challenging with conventional biological tools. Recent development of new technologies such as state of art imaging instruments and microfabrication techniques compatible with biological systems have provided many exciting opportunities to dissect complex and dynamic immune cell interactions; new microscopy techniques enable us to observe stunning dynamics of immune system in real time. Microfabrication permits us to manipulate microenvironments governing molecular/cellular dynamics of immune cells to study detailed mechanisms of phenomena observed by microscopy. Also, microfabrication can be used to engineer microenvironments optimal for specific imaging techniques. In this presentation, I am going to present an example of how these two techniques can be combined to tackle challenging problems in immunology. Obviously, this strategy can readily be applied to many different fields of biology other than immunology.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.280-280
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• 2000

In this paper, we propose a method of constructing equation using bio-inspired emergent and evolutionary concepts. This method is algorithm that is based on the characteristics of the biological DNA and growth of plants. Here is. we propose a constructing method to make a DNA coding method for production rule of L-system. L-system is based on so-called the parallel rewriting mechanism. The DNA coding method has no limitation in expressing the production rule of L-system. Evolutionary algorithms motivated by Darwinian natural selection are population based searching methods and the high performance of which is highly dependent on the representation of solution space. In order to verify the effectiveness of our scheme, we apply it to one step ahead prediction of Mackey-Glass time series.

• Journal of Plant Biotechnology
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• 제42권1호
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• pp.1-5
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• 2015

The biological roles of glycogen synthase kinase 3 (GSK3) proteins have long been extensively explored in eukaryotic organisms including fungi, animals and plants. This gene family has evolutionary well conserved kinase domain and shares similar phosphorylation properties to their substrate proteins. However, their specific biological roles are surprisingly distinct in different organisms. GSK3s play key role in key regulating the cytoskeleton and metabolic processes in animal systems, but plant GSKs are involved in quite different processes, such as flower development, brassinosteroid signaling, abiotic stresses, and organogenesis. In particular, recent studies have reported the critical multiple functions of BIN2 and its related paralogues plant GSK3s during organogenesis via connecting hormonal or developmental programs. In this review, we outline the recent understanding in the versatile functions related in physiological and biochemical relevance, which are mediated by plant GSK3s in various cellular signaling.

• Journal of Plant Biotechnology
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• 제40권3호
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• pp.111-124
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• 2013

Research on the basic interaction of radiation with biological systems has contributed to human society through various applications in pharmaceutical, medicine, agriculture and other technological developments. In the agricultural sciences and food technology sectors, the last few decades have witnessed a large number of pertinent works regarding the utilization of radiation for evolution of superior varieties of agricultural crops of economic importance. This review presents general information about the effect of radiation on plant specificity, dose response, and benefits. There has been summarized of the effects observed after exposure and influenced by several factors including plant characteristics and radiation features. We also report on the effect of ${\gamma}$-irradiations on plants, focusing on metabolic alterations, modifications of growth and development and changes in biochemical pathways.

• Mass Spectrometry Letters
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• 제5권1호
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• pp.1-11
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• 2014

Lipids play important roles in biological systems; they store energy, play a structural role in the cell membrane, and are involved in cell growth, signal transduction, and apoptosis. Phospholipids (PLs) in particular have received attention in the medical and lipidomics research fields because of their involvement in human diseases such as diabetes, obesity, atherosclerosis, and many cancers associated with lipid metabolic disorders. Here I review experimental strategies for PL analysis based on nanoflow liquid chromatography-electrospray ionization-tandem mass spectrometry (nLC-ESI-MSn). In particular, discussed are lipid extraction methods, nanoflow LC separation of PLs, effect of ionization modifiers on the ESI of PLs, influence of chain lengths and unsaturation degree of acyl chains of PLs on MS intensity, structural determination of the molecular structure of PLs and their oxidized products, and quantitative profiling of PLs from biological samples such as tissue, urine, and plasma in relation to cancer and coronary artery disease.

• Applied Biological Chemistry
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• 제34권1호
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• pp.8-13
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• 1991

자동 산화된 지방질이 효소 활성에 미치는 영향을 알아보기 위하여 각기 다른 수분활성도하에서 산화시킨 모델 시료에 대하여 산화 정도를 측정하고 분리된 단백질의 용해도 및 효소 활성도를 분석한 결과 산화가 진행되면서 과산화물가와 thiobarbituric acid(TBA)가는 증가한 반면 단백질의 용해도는 감소되고 호소 활성은 수분활성도가 높을수록 크게 감소되었다.

• 대한전기학회논문지:시스템및제어부문D
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• 제52권3호
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• pp.134-141
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• 2003

PID controllers with constant gains have been widely used in various control systems due to its powerful performance and easy implementation. But it is difficult to have uniformly good control performance in all operating conditions. In this paper, we propose a nonlinear variable PR controller with immune feedback mechanism. An immune feedback mechanism is based on the functioning of biological T-cells, they include both an active term, which controls response speed. and an inhibitive term, which controls stabilization effect. Therefore, the proposed nonlinear PID controller is based on immune responses of biological. immune feedback mechanism which is the cell mediated immunity and In order to choose the optimal nonlinear PID controller games, we also propose the tuning algorithm of nonlinear function parameter in immune feedback mechanism. To verify performance of the proposed algorithm, the speed control of nonlinear DC motor are performed. Front the simulation results, we have found that the proposed algorithm is more superior to the conventional constant fain PID controller.

• Animal cells and systems
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• 제16권1호
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• pp.57-68
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• 2012

Two new harpacticoid species belonging to the genera $Microarthridion$ Lang, 1944 (Tachidiidae) and $Nitocra$ Boeck, 1864 (Ameiridae) are recorded from underground caves in the karst area of Ninh Binh Province, North Vietnam. $Microarthridion$ $thanhi$ n. sp. is distinguished from congeneric species by the number of setae on the antennary exopod, the structure of leg 5 in both sexes, and the finger-like process modified from an outer distal pinnate seta of the third endopodal segment of leg 2 in the male. $Nitocra$ $vietnamensis$ n. sp. has the character combination of six setae on the ellipsoidal exopod of leg 5 in both sexes, the first endopodal segment of leg 1 shorter than the whole exopod, the seta/spine armature of an inner seta of P2-P4 enp-1 and four elements on P2 enp-3, and the reduction of the proximal endite to a seta on the maxillary syncoxa.

• Animal cells and systems
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• 제5권3호
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• pp.225-229
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• 2001

Nek2 is a mammalian protein kinase that is structurally homologous to NIMA, a mitotic regulator in Aspergillus nidulans. To understand cellular processes in which Nek2 participates during mammalian development, we investigated the expression and subcellular localization of Nek2 in vivo. The Nek2 protein was detected in spermatocytes and in a fraction of actively dividing ovarian follicle cells and of embryonic tissues. We also observed that Nek2 was localized in both the nucleus and centrosome in embryonic cells. Such localization pattern supports the proposal that Nek2 is a mitotic regulator that is involved in multiple cell cycle events during mammalian development.