Browse > Article
http://dx.doi.org/10.5010/JPB.2015.42.1.1

The functional roles of plant glycogen synthase kinase 3 (GSK3) in plant growth and development  

Ryu, Hojin (Department of Biology, Chungbuk National University)
Publication Information
Journal of Plant Biotechnology / v.42, no.1, 2015 , pp. 1-5 More about this Journal
Abstract
The biological roles of glycogen synthase kinase 3 (GSK3) proteins have long been extensively explored in eukaryotic organisms including fungi, animals and plants. This gene family has evolutionary well conserved kinase domain and shares similar phosphorylation properties to their substrate proteins. However, their specific biological roles are surprisingly distinct in different organisms. GSK3s play key role in key regulating the cytoskeleton and metabolic processes in animal systems, but plant GSKs are involved in quite different processes, such as flower development, brassinosteroid signaling, abiotic stresses, and organogenesis. In particular, recent studies have reported the critical multiple functions of BIN2 and its related paralogues plant GSK3s during organogenesis via connecting hormonal or developmental programs. In this review, we outline the recent understanding in the versatile functions related in physiological and biochemical relevance, which are mediated by plant GSK3s in various cellular signaling.
Keywords
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Bergmann DC, Sack FD (2007) Stomatal development. Annu Rev Plant Biol 58 : 163-181   DOI
2 Cai Z, Liu J, Wang H, Yang C, Chen Y, Li Y, Pan S, Dong R, Tang G, Barajas-Lopez Jde D, Fujii H, Wang X (2014) GSK3-like kinases positively modulate abscisic acid signaling through phosphorylating subgroup III SnRK2s in Arabidopsis. Proc Natl Acad Sci USA 111 : 9651-9656   DOI
3 Charrier B, Champion A, Henry Y, Kreis M (2002) Expression profiling of the whole Arabidopsis shaggy-like kinase multigene family by real-time reverse transcriptase-polymerase chain reaction. Plant Physiol 130 : 577-590   DOI
4 Cho H, Ryu H, Rho S, Hill K, Smith S, Audenaert D, Park J, Han S, Beeckman T, Bennett MJ, Hwang D, De Smet I, Hwang I (2014) A secreted peptide acts on BIN2-mediated phosphorylation of ARFs to potentiate auxin response during lateral root development. Nat Cell Biol 16 : 66-76
5 Choe S, Schmitz RJ, Fujioka S, Takatsuto S, Lee MO, Yoshida S, Feldmann KA, Tax FE (2002) Arabidopsis brassinosteroid-insensitive dwarf12 mutants are semidominant and defective in a glycogen synthase kinase 3beta-like kinase. Plant Physiol 130 : 1506-1515   DOI
6 Dal Santo S, Stampfl H, Krasensky J, Kempa S, Gibon Y, Petutschnig E, Rozhon W, Heuck A, Clausen T, Jonak C (2012) Stress-induced GSK3 regulates the redox stress response by phosphorylating glucose-6-phosphate dehydrogenase in Arabidopsis. Plant Cell 24 : 3380-3392   DOI
7 Gudesblat GE, Betti C, Russinova E (2012) Brassinosteroids tailor stomatal production to different environments. Trends Plant Sci 17 : 685-687   DOI
8 Gudesblat GE, Schneider-Pizon J, Betti C, Mayerhofer J, Vanhoutte I, van Dongen W, Boeren S, Zhiponova M, de Vries S, Jonak C, Russinova E (2012) SPEECHLESS integrates brassinosteroid and stomata signalling pathways. Nat Cell Biol 14 : 548-554   DOI   ScienceOn
9 Guilfoyle T (2007) Plant biology: sticking with auxin. Nature 446 : 621-622   DOI
10 Guilfoyle TJ, Hagen G (2007) Auxin response factors. Curr Opi Plant Biol 10 : 453-460   DOI
11 He JX, Gendron JM, Yang Y, Li J, Wang ZY (2002) The GSK3-like kinase BIN2 phosphorylates and destabilizes BZR1, a positive regulator of the brassinosteroid signaling pathway in Arabidopsis. Proc Natl Acad Sci USA 99 : 10185-10190   DOI
12 Jonak C, Heberle-Bors E, Hirt H (1995) Inflorescence-specific expression of AtK-1, a novel Arabidopsis thaliana homologue of shaggy/glycogen synthase kinase-3. Plant Mol Biol 27 : 217-221   DOI
13 Jonak C, Hirt H (2002) Glycogen synthase kinase 3/SHAGGY-like kinases in plants: an emerging family with novel functions. Trends Plant Sci 7 : 457-461   DOI
14 Khan M, Rozhon W, Bigeard J, Pflieger D, Husar S, Pitzschke A, Teige M, Jonak C, Hirt H, Poppenberger B (2013) Brassinosteroid-regulated GSK3/Shaggy-like kinases phosphorylate mitogen-activated protein (MAP) kinase kinases, which control stomata development in Arabidopsis thaliana. J Biol Chem 288 : 7519-7527   DOI   ScienceOn
15 Kim TW, Michniewicz M, Bergmann DC, Wang ZY (2012) Brassinosteroid regulates stomatal development by GSK3-mediated inhibition of a MAPK pathway. Nature 482 : 419-422   DOI   ScienceOn
16 Kutschera U, Wang ZY (2012) Brassinosteroid action in flowering plants: a Darwinian perspective. J Exp Bot 63 : 3511-3522   DOI
17 Lampard GR, Bergmann DC (2007) A Shout-Out to Stomatal Development: How the bHLH Proteins SPEECHLESS, MUTE and FAMA Regulate Cell Division and Cell Fate. Plant signaling & behavior 2 : 290-292   DOI
18 Lau S, Jurgens G, De Smet I (2008) The evolving complexity of the auxin pathway. The Plant cell 20 : 1738-1746   DOI
19 Ryu H, Cho H, Bae W, Hwang I (2014) Control of early seedling development by BES1/TPL/HDA19-mediated epigenetic regulation of ABI3. Nature Commun 5 : 4138
20 Li J, Nam KH (2002) Regulation of brassinosteroid signaling by a GSK3/SHAGGY-like kinase. Science 295 : 1299-1301
21 Ryu H, Cho H, Kim K, Hwang I (2010) Phosphorylation dependent nucleocytoplasmic shuttling of BES1 is a key regulatory event in brassinosteroid signaling. Mol Cells 29 : 283-290   DOI
22 Ryu H, Kim K, Cho H, Park J, Choe S, Hwang I (2007) Nucleocytoplasmic shuttling of BZR1 mediated by phosphorylation is essential in Arabidopsis brassinosteroid signaling. Plant Cell 19 : 2749-2762   DOI
23 Saidi Y, Hearn TJ, Coates JC (2012) Function and evolution of 'green' GSK3/Shaggy-like kinases. Trends Plant Sci 17 : 39-46   DOI
24 Sutherland C (2011) What Are the bona fide GSK3 Substrates? Inter J Alzheimer's Disease 2011 : 505607
25 Tang W, Deng Z, Oses-Prieto JA, Suzuki N, Zhu S, Zhang X, Burlingame AL, Wang ZY (2008) Proteomics studies of brassinosteroid signal transduction using prefractionation and two-dimensional DIGE. Mol Cell Proteom : MCP 7 : 728-738
26 Vert G, Walcher CL, Chory J, Nemhauser JL (2008) Integration of auxin and brassinosteroid pathways by Auxin Response Factor 2. Proc Natl Acad Sci USA 105 : 9829-9834   DOI
27 Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J (2005) A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis. Cell 120 : 249-259   DOI
28 Zhang D, Chen ZG, Liu SH, Dong ZQ, Dalin M, Bao SS, Hu YW, Wei FC (2013) Galectin-3 gene silencing inhibits migration and invasion of human tongue cancer cells in vitro via downregulating beta-catenin. Acta Pharm Sinica 34 : 176-184   DOI