• 제목/요약/키워드: Biological mechanism

검색결과 1,500건 처리시간 0.031초

불안의 신경생물학 (Neurobiology of Anxiety)

  • 류성곤;한창환
    • 생물정신의학
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    • 제8권1호
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    • pp.71-78
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    • 2001
  • The current understanding of the neurobiology of anxiety is generally based on experimental animal model, empirical effective psychopharmacological agents, chemical and naturalistic challenge paradigms, and psychoendocinological assessment. This article focuses on reviewing neuroanantomical, neuroendocinological and neurofunctional research of anxiety disorder. In the decade ahead, we anticipate that extension of current research and the new integrated approach promise novel insight into mechanism of anxiety.

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Molecular Aspects of Some Photobiological Receptors

  • Song, Pill-Soon
    • Applied Biological Chemistry
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    • 제20권1호
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    • pp.10-25
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    • 1977
  • The photobiological receptors of phototactic, phototropic, and photomorphogenic responses of various organisms have been described in terms of spectroscopic, photophysical and photochemical properties which may be relevant in elucidating the energy transduct ion mechanism(s) in photobiology. The photoreceptors discussed include carotenoids, flavins, stentorin and phytochrome. Although the molecular modes of their photobiological action still remain largely unexplained, it is possible to suggest several primary molecul ar processes of the photoreceptors in eliciting responses of various organisms to light.

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RNA Helicase activity of SecA protein of Escherichia coli

  • Park, Sukyung;Kim, Hyoungman
    • 한국생물물리학회:학술대회논문집
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    • 한국생물물리학회 1996년도 정기총회 및 학술발표회
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    • pp.24-24
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    • 1996
  • SecA protein of E. coli is essential for the translocation of various precursor proteins across the plasma membrane. Along with it, SecA protein interacts with precursor proteins, SecY/E, SecB and is an ATPase which has multiple ATP binding sites. There is little known about the regulation mechanism of the protein translocation machinery. (omitted)

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High Efficiency in Phosphorescent Organic Light-Emitting Doides Using Carbazole Type Exciton Blocking layer

  • Kim, Sung-Hyun;Jang, Jyong-Sik;Lee, Jun-Yeob
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2007년도 7th International Meeting on Information Display 제7권1호
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    • pp.1019-1022
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    • 2007
  • High efficiency in Phosphorescent Organic lightemitting diodes using carbazole type exciton blocking layer were investigated and detailed mechanism for light emission process was studied. Efficiency of green PHOLEDs was enhanced by a factor 3.7.

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온도변화에 따른 생물활성탄의 생물학적 재생에 미치는 영향 (Effect of Bioregeneration for Temperature Variation by Biological Activated Carbon)

  • 류성호;박중현
    • 상하수도학회지
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    • 제11권4호
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    • pp.71-79
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    • 1997
  • Biological Activated Carbon (BAC) process is widely used for the advanced water treatment, but it's mechanisms have not been well understood, especially the relationship between biodegradation and carbon adsorption. Also the phenomenon of bioregeneration has been confused that previously occupied adsorption sites appear to be made available through the actions of microorganisms. Therefore, the objectives of this study examines closely the mechanism of bioregeneration by temperature variation, especially low temperature.

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Identification and Characterization of Genes that are Induced after Cadmium Exposure

  • Lee, Mi-Ock
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-1
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    • pp.73-73
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    • 2003
  • The heavy metal cadmium is a xenobiotic toxicant of environmental and occupational concern and it has been classified as a human carcinogen. Inhalation of cadmium has been implicated in the development of emphysema and pulmonary fibrosis, but, the detailed mechanism by which cadmium induces adverse biological effects is not yet known. Therefore, we undertook the investigation of genes that are induced after cadmium exposure to illustrate the mechanism of cadmium toxicity. (omitted)

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ZR-75-1 human breast cancer cells to study the mechanism of action of PAHs

  • Min, Kyung-Nan;Sheen, Yhun-Yhong
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.286.1-286.1
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    • 2002
  • Recent industrial society has human widely exposed to PAHs that are comming from the incomplete combustion of organic material as widespread environmental contaminants. Biological activities of PAHs are not known although PAHs are considered as carcinogens. PAHs in the mammalian cells affect CYP 1A1 gene expression as well as other phase II drug metabolizing enzymes as UDPGT, NMOR etc. The mechanism of action of PAHs has been studied extensively, however it is not clear how PAHs turn on CYPIAI in human breast cancer. (omitted)

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The Practical Application of Aqueous Two-Phase Processes for the Recovery of Biological Products

  • Rito-Palomares, Marco
    • Journal of Microbiology and Biotechnology
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    • 제12권4호
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    • pp.535-543
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    • 2002
  • Although the generic implementation of aqueous two-phase systems (ATPS) processes for the recovery of biological products has been exploited for several years, this has not resulted in a wide adoption of the technique. The main reasons involve the poor understanding of the mechanism governing phase formation and the behavior of solute partitioning in ATPS processes, the cost of phase forming polymers, and the necessary extended time to optimize the technique. In this review paper, some of the practical disadvantages attributed to ATPS are addressed. The practical approach exploited to design ATPS processes, the application to achieve process integration, the extended use for the recovery of high-value products, and the recent development of new low-cost ATPS, are discussed. It is proposed that the trend of the practical application of ATPS processes for the recovery of biological products will involve the purification of new high-value bioparticulate products with medical applications. Such a trend will give new impetus to the technique, and will draw attention from industries needing to develop new, and improve existing, commercial processes.

Bio-Inspired Green Nanoparticles: Synthesis, Mechanism, and Antibacterial Application

  • Velusamy, Palaniyandi;Kumar, Govindarajan Venkat;Jeyanthi, Venkadapathi;Das, Jayabrata;Pachaiappan, Raman
    • Toxicological Research
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    • 제32권2호
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    • pp.95-102
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    • 2016
  • In the recent years, noble nanoparticles have attracted and emerged in the field of biology, medicine and electronics due to their incredible applications. There were several methods have been used for synthesis of nanoparticles such as toxic chemicals and high energy physical procedures. To overcome these, biological method has been used for the synthesis of various metal nanoparticles. Among the nanoparticles, silver nanoparticles (AgNPs) have received much attention in various fields, such as antimicrobial activity, therapeutics, bio-molecular detection, silver nanocoated medical devices and optical receptor. Moreover, the biological approach, in particular the usage of natural organisms has offered a reliable, simple, nontoxic and environmental friendly method. Hence, the current article is focused on the biological synthesis of silver nanoparticles and their application in the biomedical field.

CdTe Quantum Dots as Fluorescent Probes for Josamycin Determination

  • Peng, Jinyun;Nong, Keliang;Mu, Guangshan;Huang, Fengying
    • Bulletin of the Korean Chemical Society
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    • 제32권8호
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    • pp.2727-2731
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    • 2011
  • A new method for the determination of josamycin has been developed based on quenching of the fluorescence of 3-mercaptopropionic acid-capped CdTe quantum dots (MPA-CdTe QDs) by josamycin in ethanol. Reaction time, interfering substances on the fluorescence quenching, and mechanism of the interaction of CdTe QDs with josamycin were investigated. Under optimum conditions, the relative fluorescence intensity was linearly proportional to the concentration of josamycin between 12.0 and 120.0 ${\mu}g\;mL^{-1}$ with a correlation coefficient of 0.9956 and a detection limit of 2.5 ${\mu}g\;mL^{-1}$. The proposed method was successfully applied to commercial tablets, and the results were satisfactory, i.e. consistent with those of high-performance liquid chromatography (HPLC).