• Title/Summary/Keyword: Biological Signal

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The Matrix Effect of Biological Concomitant Element on the Signal Intensity of Ge, As, And Se in Inductively Coupled Plasma/Mass Spectrometry

  • Park, Kyung-Su;Kim, Sun-Tae;Kim, Young-Man;Kim, Yun-je;Lee, Won
    • Bulletin of the Korean Chemical Society
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    • v.23 no.10
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    • pp.1389-1393
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    • 2002
  • The non-spectroscopic interference effects that occurred in inductively coupled plasma/mass spectrometry were studied for Ge, As and Se in human urine and serum. Many biological samples contain Na, K, Cl and organic compounds, which may cause the enhancement and depression on the analyte signal. The effect of 1% concomitant elements such as N, Cl, S, P, C, Na, and K on a 100 ㎍/L germanium, arsenic and selenium signal has been investigated by ICP/MS. The interference effects were not in the same direction. It appeared that concomitant elements such as Cl, S, and C induce an enhancement effect, whereas N and P did not show any significant effect. And, Na and K caused a depression. We have found a link between the abundance of analytes and the ionization potential of concomitant elements (eV), except carbon and nitrogen.

On-line Measurement of Buffer Capacity of a Fermentation medium and Estimation of Organic Aicd Production (발효배지의 완충용량의 온라인 측정 및 유기산 생산 추정)

  • Hur, Won;Jung, Yoon-Keun
    • KSBB Journal
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    • v.13 no.4
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    • pp.461-467
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    • 1998
  • A fermentation system was supplemented with a device for the measurement of the durations of alkali pump feeding for automatic pH control and an A/D convertor for precise monitoring of pH value by computer. A software program was developed to measure buffer capacities from the pH signal and the pH control signal during fermentation. By measuring the buffer capacity on-line, levels of acetic acid were estimated by a software sensor using pH signal in a fermentation process of E.coli growing in a minimal medium. The measured values of acetic acid showed correlation to those of estimated by the software sensor. Lacitic acid production was also successfully estimated by the values of buffer capacities measured on-line.

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Application of the H Infinity Control Principle to the Sodium Ion Selective Gating Channel on Biological Excitable Membranes

  • Hirayama, Hirohumi
    • International Journal of Control, Automation, and Systems
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    • v.2 no.1
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    • pp.23-38
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    • 2004
  • We proposed the infinity control principle to evaluate the Biological function. The H infinity control was applied to the Sodium (Na) ion selective gating channel on the excitable cellular membrane of the neural system. The channel opening, closing and inactivation processes were expressed by movements of three gates and one inactivation blocking particle in the channel pore. The rate constants of the channel state transition were set to be voltage dependent. The temporal changes in amounts per unit membrane area of the channel states were expressed by means of eight differential equations. The biochemical mimetic used to complete the Na ion selective channel was regarded as noise. The control inputs for ejecting the blocking particle with plugging in the channel pore were set for the active transition from inactivated states to a closed or open state. By applying the H infinity control, we computed temporal changes in the channel states, observers, control inputs and the worst case noises. The present paper will be available for evaluating the noise filtering function of the biological signal transmission system.

Sensitivity illumination system using biological signal (생체신호를 이용한 감성조명 시스템)

  • Han, Young-Oh;Kim, Dong-Woo
    • The Journal of the Korea institute of electronic communication sciences
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    • v.9 no.4
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    • pp.499-508
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    • 2014
  • In this paper, we implemented a LED sensitivity illumination system, being driven in response to changes in the biological signals of GSR and PPG signal. After measuring biological signals of a human body from GSR and PPG sensor modules, MCU decided the state of relaxation or arousal of the subject, being based on the wake relaxation identifying map proposed in this paper. A developed LED sensitivity illumination system makes the subject to reach a normal state by giving a change of the LED illumination color, corresponding to a state of the subject.

Multidimensional Adaptive Noise Cancellation of Stress ECG Signal

  • Gautam, Alka;Lee, Young-Dong;Chung, Wan-Young
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2008.05a
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    • pp.285-288
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    • 2008
  • In ubiquitous computing environment the biological signal ECG (Electrocardiogram signal) is usually recorded with noise components. Adaptive interference (or noise) canceller do adaptive filtering of the noise reference input to maximally match and subtract out noise or interference from the primary (signal plus noise) input thereby adaptively eliminate unwanted interference from the ECG signal. Measured Stress ECG (or exercise ECG signal) signal have three major noisy component like baseline wander noise, motion artifact noise and EMG (Electro-mayo-cardiogram) noise. These noises are not only distorted signal but also root of incorrect diagnosis while ECG data are analyzed. Motion artifact and EMG noises behave like wide band spectrum signals, and they considerably do overlapping with the ECG spectrum. Here the multidimensional adaptive method used for filtering which is more effective to improve signal to noise ratio.

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Polyamine Stimulation of arcA Expression in Escherichia coli

  • Rhee, Mun-Su;Kim, Young-Sik;Park, Seon-Young;Park, Myung-Hun;Kim, Bo-Min;Kang, Seong-Uk;Lee, Kui-Joo;Lee, Jong-Ho
    • Journal of Microbiology
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    • v.40 no.4
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    • pp.305-312
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    • 2002
  • The effects of two natural polyamines (putrescine and spermidine) on the synthesis of ArcA, a response regulator of the Arc two-component signal transduction system, were studied using an E. coli mutant deficient in polyamine biosynthesis. Endogenous polyamine deficiency of the mutant resulted in marked reduction in the ArcA level determined by Western blot analysis. Putrescine supplement to the growth medium effectively increased the ArcA level of the mutant in a concentration-dependent manner. Spermidine also stimulated the ArcA level in the mutant to a greater degree than putrescine. Expression of arcA'::lacZ operon fusion in the mutant was stimulated 6-fold and 10-fold by putrescine and spermidine at a 1mM concentration, respectively, indicating that the stimulatory effect of the polyamines on ArcA synthesis is due to transcriptional induction, and that spermidine is a more potent arcA inducer than putrescine. The polyamine-dependent arcA'::lacZ induction was growth-phase-dependent and independent of either arcA or fnr which are two regulators involved in anaerobic stimulation of the Arch level. These results suggested that putrescine and spermidine polyamines may be potential intracellular signal molecules in the control of arcA expression, and thereby may play an important role in cellular metabolism.

In-situ Warpage Measurement Technique Using Impedance Variation (임피던스 변화를 이용한 실시간 기판 변형 측정)

  • Kim, Woo Jae;Shin, Gi Won;Kwon, Hee Tae;On, Bum Soo;Park, Yeon Su;Kim, Ji Hwan;Bang, In Young;Kwon, Gi-Chung
    • Journal of the Semiconductor & Display Technology
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    • v.20 no.1
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    • pp.32-36
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    • 2021
  • The number of processes in the manufacture of semiconductors, displays and solar cells is increasing. And as the processes is performed, multiple layers of films and various patterns are formed on the wafer. At this time, substrate warpage occurs due to the difference in stress between each film and pattern formed on the wafer. the substrate warping phenomenon occurs due to the difference in stress between each film and pattern formed on the wafer. We developed a new warpage measurement method to measure wafer warpage during real-time processing. We performed an experiment to measure the presence and degree of warpage of the substrate in real time during the process by adding only measurement equipment for applying additional electrical signals to the existing ESC and detecting the change of the additional electric signal. The additional electrical measurement signal applied at this time is very small compared to the direct current (DC) power applied to the electrostatic chuck whit a frequency that is not generally used in the process can be selectively used. It was confirmed that the measurement of substrate warpage can be easily separated from other power sources without affecting.

Decomposition of EMG Signal Using MAMDF Filtering and Digital Signal Processor

  • Lee, Jin;Kim, Jong-Weon;Kim, Sung-Hwan
    • Journal of Biomedical Engineering Research
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    • v.15 no.3
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    • pp.281-288
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    • 1994
  • In this paper, a new decomposition method of the interference EMG signal using MAMDF filtering and digital signal processor. The efficient software and hardware signal processing techniques are employed. The MAMDF filter is employed in order to estimate the presence and likely location of the respective templates which may include in the observed mixture, and high-resolution waveform alignment is employed in order to provide the optimal combination set and time delays of the selected templates. The TMS320C25 digital signal processor chip is employed in order to execute the intensive calculation part of the software. The method is verified through a simulation with real templates which are obtain ed from needle EMG. As a result, the proposed method provides an overall speed improvement of 32-40 times.

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Design and Implementation of Biological Signal Measurement Algorithm for Remote Patient Monitoring based on IoT (IoT기반 원격환자모니터링을 위한 생체신호 측정 알고리즘 설계 및 구현)

  • Jung, Ae-Ran;You, Yong-Min;Lee, Sang-Joon
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.8 no.6
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    • pp.957-966
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    • 2018
  • Recently, the demand for remote patient monitoring based on IoT has been increased due to aging population and an increase in single-person household. A non-contact biological signal measurement system using multiple IR-UWB radars for remote patient monitoring is proposed in this paper. To reduce error signals, a multilayer Subtraction algorithm is applied because when the background subtraction algorithm was applied to the biological signal processing, errors occurred such as voltage noise and staircase phenomenon. Therefore, a multilayer background subtraction algorithm is applied to reduce error occurrence. The multilayer background subtraction algorithm extracts the signal by calculating the amount of change between the previous clutter and the current clutter. In this study, the SVD algorithm is used. We applied the improved multilayer background subtraction algorithm to biological signal measurement and computed the respiration rate through Fast Fourier Transform (FFT). To verify the proposed system using IR-UWB radars and multilayer background subtraction algorithm, the respiration rate was measured. The validity of this study was verified by obtaining a precision of 97.36% as a result of a control experiment with Neulog's attachment type breathing apparatus. The implemented algorithm improves the inconvenience of the existing contact wearable method.