• Journal of Ocean Engineering and Technology
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• v.37 no.4
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• pp.172-179
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• 2023

Biofouling initiated by biofilm (slime) formation is a key challenge for practical ocean engineering and construction. This study evaluated a new anti-biofilm technology using bioelectricity. The anti-microfouling electrical technology is based on the principles of the bioelectric effect, known as the application of an electrostatic force for biofilm removal. Previously, the electricity was optimized below 0.82V to avoid electrolysis, which can prevent the production of biocides. A test boat comprised of microelectronics for electrical signal generation with electrodes for an anti-biofouling effect was developed. The tests were conducted in the West Sea of Korea (Wangsan Marina, Incheon) for three weeks. The surface biofouling was quantified. A significant reduction of fouling was observed under the bioelectric effect conditions, with approximately 30% enhanced prevention of fouling progress (P<0.05). This technology can be an alternative eco-friendly technique for anti-microfouling that can be applied for canals, vessels, and coastal infrastructure because it does not induce electrolysis.

• Journal of Oriental Neuropsychiatry
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• v.11 no.1
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• pp.83-96
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• 2000

Objectives: In order to study the effect of the oriental medical therapy on the patients who visited Neuropsychiatry and oriental medical differentiation of symptoms and signs with ABR (Autonomic Bioelectric Response recorder)-2000, these clinical studies were performed. Methods: Sixty six patients with headache were classified into three groups; the first is tension headache, the second is migraine headache, the last is the others, each group was investigated of a various characteristic, the effect of the oriental medical therapy and stress was measured by ABR-2000. Result: 1. According to the statics, the tention headache's rate was higher than migraine; on the whole woman's rate was higher than man's. however in the migraine the rate of sex was equal. 2. According to the cause facter, oversensitiveness, overexertion, dyspepsia, etc. were numorous in the order. 3. According to the oriental medical differentiation of symptoms and signs, the rate of stagnation of the liver-qi' s fire-transmission(肝鬱化火) and deficiency of qi(氣虛), these two types were highest. result of analyzing ABR-2000 is that stagnation of the liver-qi's fire-transmission(肝鬱化火) is the highest stress. 4. According to treatment rate, 80.3 percent of patients satisfied of treatment.

• Journal of the Korean Society of Clothing and Textiles
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• v.35 no.7
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• pp.713-720
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• 2011

This study investigated the effect of cold acclimatization training on body composition including weight, fat mass, and muscle mass with 10 subjects (5 males and 5 females). During the 3-week acclimatization training program, they visited an artificial climate chamber ($15^{\circ}C$) 15 times and were exposed to cold environment with light clothing for 2 hours. Body composition was measured before and after cold training using bioelectric impedance analysis that was later compared by a paired t-test. In the process of thermoregulation, muscle contraction was accompanied by increased substrate metabolism for rising heat production. After cold training, the muscle mass increased and fat mass decreased significantly (p<.1, p<.05), subsequently the body composition changed. It was found that cold acclimatization training could be used as a treatment for obesity. It was suggested that further investigation on the long term effects of mild cold exposure using clothing and its potential applicability as an obesity treatment.

• Korean Journal of Acupuncture
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• v.30 no.3
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• pp.185-192
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• 2013

Objectives : Many studies have investigated the electric specificity of meridian and acupoint. However, the definition about the real substance of 'Ki(Qi)' that flows in the meridian has not been established yet. The authors hypothesized that the 'Ki(Qi)' may be the very 'bioelectricity' of western medicine, from two common features that they are not visible with naked eyes and that they function in the living body only. Methods : 20 healthy adults participated in this study. Heart rate was measured before and after exercise. Acupuncture was performed at PC6 immediately after exercise with counter balance in the first experiment. In the second experiment, acupuncture group was further divided to the three groups, i.e. glove acupuncture group, manual acupuncture group, and NaCl acupuncture group. In the glove group, acupuncturist put on the two folds of latex gloves to block bioelectric currents between the acupuncturist and subject. In the NaCl group, acupuncturist had his fingertips wet with NaCl solution. Results : Exercise increased Heart Rate and acupuncture at PC6 inhibited this increase. In the second experiment, the significant difference compared to the comtrol group was the most in NaCl acupuncture and the least in Glove acupuncture. However, there was no significant difference between three groups. Conclusions : The results of this study seem to be deficient as a conclusive evidence for the hypothesis that the 'Ki(Qi)' of Korean Medicine is the 'bioelectricity' of western medicine.

• Journal of Oral Medicine and Pain
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• v.14 no.1
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• pp.19-24
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• 1989

The purpose of this study was to investigate the reliability of electromyographic examination in a day and detect the objective measurement timing of electromyography. 18 normal students who were in dental collage of C national university were selected for this study. They had no symptoms on temporomandibular joint area, no restorations and missing tooth on dentition. Their molar relationship was normal or class I of Angle's classification. Electromyography had been taken every one hour from 9:00 A.M. to 5:00 P.M. in the state of clenching and rest by using Bioelectric processor EM2 interfaced with mandibular kinesiograph K-6 diagnostic system. We compared and analyzed the variances of electromyography values of each subjects. The obtained results were as follows : There were no significant differences on variability of electromyography values in each state clenching and rest. In the aspect of this circumstances, the use of electromyography could be a good objective procedure to diagnose the temporomandibular disorders and to detect the effect to the treatment of temporomandibular disorders at any time in a day from 9:00 A.M. to 5:00 P.M.

• Journal of Preventive Medicine and Public Health
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• v.37 no.1
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• pp.72-79
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• 2004

Objectives : This cross-sectional study aimed to quantify the relationship between the bone mineral density at the os calcis and the body mass composition in healthy children. Methods : The areal bone mineral density was measured at the os calcis with peripheral dual energy X-ray absorptiometry. The fat free mass, fat mass and percentage fat mass were measured using bioelectric impedance, in 237 Korean children, aged 9 to 12 years. The sexual maturity was determined by self assessment, using standardized series of the 5 Tanner stage drawings, accompanied by explanatory text. Results : From multiple linear regression models, adjusted for age, sexual maturity and height, the fat free mass was found to be the best predictor of the calcaneal bone mineral density in both sexes. About 15 and 20% variabilities were found in the calcaneal bone mineral densities of the boys and girls, respectively, which can be explained by the fat free mass. After weight adjustment, the percentage fat mass was negatively associated with the calcaneal bone mineral density in both sexes. Conclusions : The findings of this study suggest that the fat free mass, among the body compositions, is the major determinant of bone mineral density at the os calcis in Korean children aged 9 to 12 years. Obesity, defined as the percentage fat mass, is assumed to have a negative effect on the calcaneal bone density in children of the same weight.

• Journal of Korean Society of Environmental Engineers
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• v.33 no.9
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• pp.692-700
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• 2011

The use of electric field has been studied as an alternative for biofilm control dominated by disinfectants and antibiotics. This technology would be advantageous in the environmental respect that biofilm can be controlled based on electron transfer, not using chemical disinfectants and antibiotics. Control mechanisms which were reported by earlier studies are organized as; (1) bacterial adhesion control by electrostatic repulsion at a negative current, (2) bacterial adhesion control using bacterial motion and (3) bacterial inactivation by direct oxidation at a positive current, (4) bioelectric effect leading to biofilm inactivation. In this review article, we summarized the technologies for biofilm control using electric field and provided some application examples from previous studies.

• Journal of Oral Medicine and Pain
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• v.19 no.2
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• pp.81-97
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• 1994

두개하악장애는 환자의 신체적 소인, 관련조직의 구조적 변화, 정신적 스트레스 등의 복합적 요인에 의 발생하는 다인성 질환으로 최근 대두되는 원인중의 하나가 신체, 특히 두경부의 자세이상이다. 비정상적인 두경부자세는 하악의 위치변화를 수반하여 종종 두개하악장애를 야기시키게 되나 이를 설명할 수 있는 과학적 증거는 아직 부족한 실정이다. 저자는 두경부 자세가 교합장치물에 의해 변화되는지를 저작근의 근전도학적 측면에서 규명하고자 21세에서 26세의 치과대학생으로 치아상실 및 교합간섭이 없고 두 개하악장애의 증후 및 경부운동제한을 가지지 않은 정상인 20명을 대상으로 각도계를 사용하여 시상면상에서 인위적으로 유도한 세 가지의 두경부자세변화 (0$^{\circ}$, 30$^{\circ}$ 굴절, 45$^{\circ}$ 신전)에 따른 교합안정장치의 장착(1시 간) 전후 및 안정위와 근접촉위(초기치아접촉위)에서의 두경부 근육(측두근, 교근, 악이복근)의 근전도를 Bioelectric Microprocessor EM2ⓡ를 사용하여 측정한 후 통계학적으로 비교, 분석, 평가하여 다음과 같은 결과를 얻었다. 1. 교합안정장치 장착전 하악 안정위 및 근접촉위에서 두부의 30$^{\circ}$굴절은 악이복근의 근활성도를, 45$^{\circ}$신전은 교근 및 악이복근의 근활성도를 증가시켰다.(p<0.05) 2. 교합안정장치 장착후 하악 안정위에서 두부의 30$^{\circ}$굴절은 악이복근의 근활성도를, 45$^{\circ}$신전은 교근 및 악이복근의 근활성도를 증가시켰으며, 하악 근접촉위에서 두부의 45$^{\circ}$신전은 악이복근의 근활성도를 증가시켰다(p<0.05). 3. 교합안정장치 장착 전후 및 두부의 30$^{\circ}$굴절, 45$^{\circ}$신전에 따른 측두군 및 교근의 하악 근접촉위에서의 근활성도가 안정위에서의 근활성도에 비해 유의한 증가를 나타냈다(p<0.05).

• Journal of Korean Medicine Rehabilitation
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• v.18 no.4
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• pp.121-133
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• 2008

Objectives : MENS was used for wound healing and pain relief using bioelectric property. There are many articles on in vivo and clinical research. This article reviews articles on MENS published for recent 10 years to consider effectiveness of MENS and other fields to applicate MENS. Articles were collected from MAR, 2008 to JUN, 2008. Methods : We searched Pubmed, KSI, KERIS, KMBASE, and National assembly library using "Microcurrent Electrical Neuromuscular Stimulation" and classified the articles into subsets of foreign, Korean and wound healing, pain, relief, and increasing the range of movement(ROM). Also we evaluated their values according to the Jadad scale. Results : A total of 18 articles (Foreign-9, Korean-9) reconfirmed that MENS reduces pain, increases wound healing, ROM, and strength of muscle. In addition, MENS has effect on stress-hormone and various pain like low back pain, acute lateral epicondylitis, and plantar fascitis. And there are various styles developed. However, there is no standard protocol so the user is usually in trouble at clinic. Conclusions : MENS may be have application to various pain diseases, and further studies analysing its effectiveness are needed.

• Journal of Pharmaceutical Investigation
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• v.34 no.6
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• pp.483-489
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• 2004

Fexofenadine HCl is non-sedating histamine H1 receptor antagonist that can be used for the treatment of seasonal allergic rhinitis. The objective of this study was to investigate whether the carriers of deformable liposomes can enhance the transepithelial permeability of fexofenadine HCl across the in vitro ALI human nasal monolayer model. Characterization of this model was achieved by bioelectric measurements and morphological studies. The passage 2 and 3 of cell monolayers exhibited the TEER value of $2852\;{\pm}\;482\;ohm\;{\times}\;cm^2$ on 11 days of seeding and maintained high TEER value for 5 days. The deformable liposome of fexofenadine HCl was prepared with phosphatidylcholine (PC) and cholic acid using extruder method. The mean particle size was about 200 nm and the maximum entrapment efficiency of 33.0% was obtained in the formulation of 1% PC and $100\;{\mu}g/ml$ fexofenadine HCl. The toxicity of the deformable liposome to human nasal monolayers was evaluated by MTT assay and TEER value change. MTT assay showed that it has no toxic effect on the nasal epithelial cells in 2-hour incubation when the PC concentration was below 1%. However, deformable liposome could not enhance the transepithelial permeability $(P_{app})$ and cellular uptake of fexofenadine HCl. In conclusion, the in vitro model could be used in nasal drug transport studies and evaluation of transepithelial permeability of formulations.