• Corrosion Science and Technology
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• v.6 no.6
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• pp.286-290
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• 2007

Biocompatible Hydroxy apatite (HAp) coatings on metallic substrate by plasma spray techniques have been developed. Long-term credibility of plasma spray HAp coatings has been evaluated in physiological saline by electrochemical measurements. It was found that the corrosion resisitance of SUS316L based HAp/Ti conbined coatings was excellent even after more than 10 weeks long-term immersion. It was shown that postal heat treatment improved both the crystallinity and corrosion resistance of HAp. By lowering cooling rate during heat treatment process, less cracks produced in HAp coating layer, which lead to higher credibility of HAp during immersion in physiological saline. The ICP results showed that the dissolution level of substrate metallic ions was low and HAp coatings produced in this research can be acceptable as biocompatible materials. Also, the concentration of dissolved ions from HAp coatings with postal heat treatment was lower compared to those from samples without postal heat treatment. The adherence of HAp coatings with Ti substrate and other mechanical properties were also assessed by three-point bending test. The poor adhesion of HAp coating to titanium substrate can be improved by introducing a plasma spray titanium intermediate layer.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.16 no.6
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• pp.95-100
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• 2017

Recently, biomedical-grade texture material gauze has often been used to treat wounds. At this time, it is difficult to remove scratches and pushed gauze; if you remove it with force, the tissue may separate and bleeding may occur again. In this study, we studied a method to apply medical-grade silicone material. Similar to the research result that hypertrophic wounds reduce the thickness of scar marks. Through mini-pig experiments, we evaluated the effects on scar treatment. The test results showed that the silicone cover layer applied to the wound site had a sealing effect on the wound area, skin temperature, and histopathological examination. In conclusion, gel treatment utilizing a biocompatible substance had the effect of minimizing hypertrophic scars.

• Bulletin of the Korean Chemical Society
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• v.33 no.12
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• pp.3957-3962
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• 2012

Iron-oxide nanoparticles (IONs) with biocompatible coatings are the only nanostructural materials which have been approved by the FDA for clinical use. Common biocompatible coatings such as hydrocarbons, polymers, and silica have profound influences on critical characteristics of IONs. Recently, amino acids were introduced as a novel biocompatible coating. In the present study, the effects of amino acids on IONs synthesis and characteristics have been evaluated. Magnetite nanoparticles with L-arginine and L-lysine coatings were synthesised by a coprecipitation reaction in aqueous solvent and their characteristics were compared with naked magnetite nanoparticles. The results showed that amino acids can be a perfect coating for IONs and would increase particle stability without any significant effects on the critical properties of nanoparticles such as particle size and magnetization saturation value.

• Proceedings of the SCSK Conference
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• 2004.09a
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• pp.9-41
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• 2004

• Proceedings of the Korean Fiber Society Conference
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• 1991.06b
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• pp.19-19
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• 1991

• 대한치과보철학회:학술대회논문집
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• 2000.11a
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• pp.30-31
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• 2000

• Proceedings of the Korean Vacuum Society Conference
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• 2016.02a
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• pp.78-78
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• 2016

For the past three decades, extensive research has been performed in the surface design of new polymers for a variety of medical applications. Great progress in therapeutics and diagnostics can be attributed to these scientific advances in biomedical polymers. A variety of bioinert materials or bioactive materials using drugs, cells, and growth factors are widely utilized for the implants, devices and tissue regeneration. These materials provide an improved biocompatible materials to host, to significantly decrease or increase the host/tissue/blood response to the foreign materials. In the future, biomaterials will play a different role in modern therapeutics. New materials will be tailored to interact more on a protein and cellular level to achieve high degree of biocompatibility, biospecificity and bioacitivity. In this presentation, various biocompatible materials based on surface/bulk engineering will be demonstrated, which can be utilized as therapeutics implants and therapeutic vehicles for biologically active molecules such as cell, protein /peptide and gene.

• Journal of Environmental Science International
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• v.27 no.10
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• pp.853-863
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• 2018

In order to increase the medicinal herbs efficiency of drug delivery, vesicles contained with medicinal herbs were prepared by phosphatidylcholines and surface active agent. Vesicles loaded with medicinal herbs were characterized by UV-spectroscopy, Zetasizer. The antioxidant activity of vesicles was measured by DPPH assay and ABTS radical scavenging assays. Also, an analysis was conducted to determine the effects of anti-inflammatory of vesicles contained medicinal herbs. In addition, the whitening effects of vesicles contained medicinal herbs extract were studied via tyrosinase inhibition assay. The results of vesicles were as follows. Vesicles appeared an average diameter of approximatively 164-599 nm. All studied vesicles contained with medicinal herbs showed antioxidant, anti-inflammatory and whitening effects in a dose-dependent manner. Therefore, this experiment achieves its purpose of synthesizing of vesicles. In conclusion, we recommended that the vesicles loaded with medicinal herbs have ability for anti-aging materials. Specifically, it will apply to cosmetic ingredients.

• The Journal of the Korean dental association
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• v.48 no.11
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• pp.798-802
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• 2010

Introduction: MTA has been studied for more than 15 years since it was introduced and developed at Loma Linda University. The purpose of this review was to present the current published papers regarding MTA's biologic properties and to provide a deep insight into the material's mechanisms of actions. Results: MTA has appeared to be biocompatible in many previous researches. In addition to that, it had a potential to increase cell reactions such as proliferation and differentiation, Recently, MTA like new endodontic materials has been introduced and marketed. Conclusions: On the basis of current evidences, MT A seems to be biocompatible. Meticulous studies need to be performed to adopt new endodontic materials into clinical applications,

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.1254-1258
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• 2007

Electro-active polymer (EAP), one of the smart materials, is a new alternative offering ultra-precise movements and bio-compatibility. We present the results of the design, fabrication, and performance evaluation of a fabricated diaphragm-type polymer actuator using segmented polyurethane(SPU). This paper illustrates the relationship between the elastic modulus and maximum deflection as a key property of the Maxwell stress effect and also presents the relationship between the dielectric constant and maximum deflection as a key property of the electrostriction effect, especially in polymer actuators using SPU. A diaphragm-type actuator was used to induce an equation of the vertically distributed load by using a fully clamped circular plate as the boundary condition. To verify the equation, the results were compared to the data measured from load cell. In the near future, a low-cost check valves and bio-robot can be applied by its actuators.