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Mineral Trioxide Aggregate (MTA): Review of its biologic properties  

Kim, Eui-Seong (Yonsei University, Department of Conservative Dentistry)
Shin, Su-Jung (Yonsei University, Department of Conservative Dentistry)
Publication Information
The Journal of the Korean dental association / v.48, no.11, 2010 , pp. 798-802 More about this Journal
Abstract
Introduction: MTA has been studied for more than 15 years since it was introduced and developed at Loma Linda University. The purpose of this review was to present the current published papers regarding MTA's biologic properties and to provide a deep insight into the material's mechanisms of actions. Results: MTA has appeared to be biocompatible in many previous researches. In addition to that, it had a potential to increase cell reactions such as proliferation and differentiation, Recently, MTA like new endodontic materials has been introduced and marketed. Conclusions: On the basis of current evidences, MT A seems to be biocompatible. Meticulous studies need to be performed to adopt new endodontic materials into clinical applications,
Keywords
MTA; biocompatibility; portland cement;
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1 Oviir T, Pagoria D, Ibarra G, Geurtsen W. Effects of gray and white mineral trioxide aggregate on the proliferation of oral keratinocytes and cementoblasts. J Endod 2006; 32: 210-213.   DOI   ScienceOn
2 Koh ET, Torabinejad M, Pitt Ford TR, Brady K, MCDonald F. Mineral trioxide aggregate stimulates a biological response in human osteoblasts. J Biomed Mater Res 1997; 37: 432-439.   DOI   ScienceOn
3 Moretton TR, Brown CE Jr, Legan JJ, Kafrawy AH. Tissue reactions after subcutaneous and intraosseous implantation of mineral trioxide aggregate and ethoxybezoic acid cement. J Biomed Mater Res 2000; 52: 528-533.   DOI   ScienceOn
4 Asgary S. Eghbal MJ, Parirokh M, Ghoddusi J, Kheireh S, Brink F. Comparison of mineral trioxide aggregate's composition with Portland cements and a new endodontic cement. J Endod 2009; 35: 243-250.   DOI   ScienceOn
5 Yuan Z, Peng B, Jiang H, Bian Z, Pan P. Effect of bioaggregate on mineral associated gene expression in osteoblast cells. J Endod 2010; 36(7): 1145-1148.   DOI   ScienceOn
6 Lee SJ, Monsef M, Torabinejad M. Sealing ability of a mineral trioxide aggregate for repair of lateral perforations. J Endod 1993; 19(11): 541-544.   DOI   ScienceOn
7 De Deus G, Ximenes R, Gurgel-Filho ED, Plotkowski MC, Coutinbo-Filho T. Cytotoxicity of MTA and Portland cement on human ECV 304 endothelial cells. Int Endod J 2005; 38: 604-609.   DOI   ScienceOn
8 Perinparanayagam H, Al-Rabeah E. Osteoblasts interact with MTA surfaces and express RunX2. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 107: 590-596.   DOI   ScienceOn
9 Koulaouzidou EA, Economides N, Beltes P, Geromichalos F, Papzisis K. In vitro evaluation on the cytotoxicity of ProRoot MTA and MTA Angelus. J Oral Sci 2008; 50: 397-402.   DOI   ScienceOn
10 Balto HA. Attachment and morphological behavior of human periodontal ligament fibroblasts to mineral trioxide aggregate: a scanning electron microscope study. J Endod 2004; 30: 25-29.   DOI   ScienceOn
11 Baek SH, Plendk H Jr, Kim S. Periapical tissue responses and cementum regeneration with amalgam, SuperEBA, and MTA as root-end filling materials. J Endod 2005; 31: 444-449.   DOI   ScienceOn
12 Huang TH, Ding SJ, Hsu TC, Kao CT. Effects of mineral trioxide aggregate(MTA) extracts on mitogenactivated protein kinase activity in human osteosarcoma cell line (U2OS). Biomaterials 2003; 24: 3909-3913.   DOI   ScienceOn
13 Torabinejad M, Watson TF, Pitt Ford TR. Sealing ability of a mineral trioxide aggregate when used as a root end filling material. J Endod 1993; 19(12): 591-595.   DOI   ScienceOn
14 Nkata TT, Bae KS, Baumgartner JC. Perforations repair comparing mineral trioxide aggregate and amlgam using an anareobic bacterial leakage model. J Endod 1998; 24: 184-186.   DOI   ScienceOn
15 Zhu Q, Haglund R, Safavi KE, Spangberg LS. Adhesion of human osteoblasts on root-end filling materials. J Endod 2000; 26(7): 404-406.   DOI   ScienceOn