• Title/Summary/Keyword: Bio-system

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Lamellar-bio nano-hybrid; The Study for Stability of Catechin (Green Tea: EGCG) Using 3-Dimensional Liposome (라멜라-바이오 나노하이브리드: 3 Dimension-liposome을 이용한 카테킨(EGCG)에 안정화에 대한 연구)

  • Hong Geun, Ji;Jung Sik, Choi;Hee Suk, Kwon;Sung Rack, Cho;Byoung Kee, Jo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.30 no.2
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    • pp.201-205
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    • 2004
  • In these several years, as many people have been attracted by the functional cosmetics, there are a lot of study to enhance the stability of active ingredients for light, heat, oxygen, etc. in the academic and industrial field. Especially, catechin is well known as strong anti-oxidant, anti-inflammatory and reducing agent for oxidative stress but it is very unstable for light, heat, oxygen. etc. In this study, the stability and skin penetration of catechin are improved by 3-dimensional method. As I-dimension, porous silica is prepared using sol-gel method, and then catechin is adsorbed in pores of silica. As 2-dimension, solid lipid nanoparticles (SLN) are obtained using non-phospholipid vesicles. Finally 3-dimension is completion through lamellar phase self-organization that combines SLN catechin with skin lipid matrix. We used laser light scattering system, cyro-SEM, chromameter, HPLC and image analyzer to analyze our 3-dimentional systems. According to chromameter date, the color stability of 3-dimensional catechin is enhanced by 5-10 times compared with general liposome systems. We also confirmed through HPLC analysis that 3-dimensional catechin is more long lasting. The effect of skin penetration and wrinkle reduction are improved, too.

A Study on Magnetic Cure System Depending on Dominant Direction of Meridian using Yangdorak Diagnosis Machine with 24 Channels (24채널의 양도락진단기를 이용한 경락의 우세방향에 따른 자기치료시스템에 관한 연구)

  • Kim, Byoung-Hwa;Lee, Woo-Cheol;Han, Gueon-Sang;Sagong, Seok-Jin;Ahn, Hyun-Sik;Kim, Do-Hyun
    • Journal of the Institute of Electronics Engineers of Korea TE
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    • v.39 no.2
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    • pp.34-43
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    • 2002
  • In this paper, with the reference of the pulse wave acquired by the pulse-checking device, it is measured the impedance on the key measuring points of the 12 kyungmaks of the human body's left and right by using 24-channels Yangdorak machine. Then, based on the Fuzzy theory, this study diagnosed the each meridian's strength and weakness. After that, both the strengthening and weakening stimulus of magnetic fields are applied to the dominant direction to find out how the degree of strength and weakness of the meridian changed. Ultimately, the magnetic therapy that can stimulate the magnetic field at the time of diagnosis and thereby balancing the interactive of five-system(O-hang) have been materialized. For the stimulation of magnetic fields, a stimulating device which can change the direction and time on a specific part of the key measuring points of the limbs of 24 kyungmaks have been developed and used. The therapeutic methods are as follows. First, the strength and weakness of the meridian have been determined. Second, both the extremely weak meridian of Yin(Shade) and Yang(Shine), and the extremely strong meridian of Yin and Yang were adjusted by applying appropriate ascending and descending stimuli respectively. All these adjusting processes can now be carried out automatically on a personal computer(PC). 

Risk Assessment Tools for Invasive Alien Species in Japan and Europe (일본과 유럽의 침입외래생물 생태계위해성평가 기법)

  • Kil, Jihyon;Mun, Saeromi;Kim, Chang-Gi
    • Ecology and Resilient Infrastructure
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    • v.2 no.3
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    • pp.191-197
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    • 2015
  • Invasive alien species are considered to be one of the main factors that cause biodiversity loss. Establishment of management strategies through continuous monitoring and risk assessment is a key element for invasive alien species management policy. In the present study, we introduce examples of ecological risk assessment tools developed in Japan, Germany-Austria and Belgium. Invasive alien species have been designated in Japan based on the assessment of risks to ecosystems, human health and primary industry. German-Austrian Black List Information System categorized alien species into Black List, White List and Grey List according to their risks to biodiversity. In the Harmonia Information System developed in Belgium, invasiveness, adverse impacts on native species and ecosystem functions and invasion stages were assessed and alien species were categorized into Black List, Watch List and Alert List. These international risk assessment tools may be helpful to improve our national risk assessment protocol for the prioritization of invasive alien species management.

Development of a Photoplethysmographic method using a CMOS image sensor for Smartphone (스마트폰의 CMOS 영상센서를 이용한 광용적맥파 측정방법 개발)

  • Kim, Ho Chul;Jung, Wonsik;Lee, Kwonhee;Nam, Ki Chang
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.6
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    • pp.4021-4030
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    • 2015
  • Pulse wave is the physiological responses through the autonomic nervous system such as ECG. It is relatively convenient because it can measure the signal just by applying a sensor on a finger. So, it can be usefully employed in the field of U-Healthcare. The objects of this study are acquiring the PPG (Photoplethysmography) one of the way of measuring the pulse waves in non-invasive way using the CMOS image sensor on a smartphone camera, developing the portable system judging stressful or not, and confirming the applicability in the field of u-Healthcare. PPG was acquired by using image data from smartphone camera without separate sensors and analyzed. Also, with that image signal data, HRV (Heart Rate Variability) and stress index were offered users by just using smartphone without separate host equipment. In addition, the reliability and accuracy of acquired data were improved by developing additional hardware device. From these experiments, we can confirm that measuring heart rate through the PPG, and the stress index for analysis the stress degree using the image of a smartphone camera are possible. In this study, we used a smartphone camera, not commercialized product or standardized sensor, so it has low resolution than those of using commercialized external sensor. However, despite this disadvantage, it can be usefully employed as the u-Healthcare device because it can obtain the promising data by developing additional external device for improvement reliability of result and optimization algorithm.

Induction of Apoptosis by Methanol Extract of Gloiopeltis furcata in Human Leukemia Cell Line U937 (인체백혈병세포의 증식에 미치는 불등가사리 메탄올 추출물의 영향)

  • Choi, Woo Young;Park, Cheol;Kim, Gi Young;Lee, Won Ho;Bae, Song-Ja;Choi, Yung Hyun
    • Journal of Marine Bioscience and Biotechnology
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    • v.1 no.2
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    • pp.76-83
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    • 2006
  • Epidemiological studies have indicated that the ubiquitous consumption of seaweeds is a protective factor against some types of cancer. Previous results showed that the administration of seaweed powder or extract reduced the incidence rate of chemically induced tumorigenesis using in vivo animal model. Recently, we reported that the extracts of Gloiopeltis furcata, a kind of Korean edible seaweed, caused he cell growth inhibition of various human cancer cell lines, among them methanol extract exhibited a relatively strong antiproliferative activity. However, the molecular mechanisms of this seaweed in malignant cells have been poorly studied until now. To elucidate this problem, we investigated the effects of methanol extract of G. furcata (MEGF) on the growth inhibition in several human cancer cell lines, and further we analyzed the effects of this extract were tested on the activity of apoptosis induction in human leukemic cells. The results demonstrated that MEGF treatment resulted in the morphological changes and the growth inhibition in a dose-dependent manner. Furthermore, MEGF potently suppresses the growth of human leukemic U937 cells by induction of apoptosis, which was associated with induction of cyclin-dependent kinase inhibitor p21(WAF1/CIP1) in a tumor suppressor p53-independent fashion and up-regulation of Fas/FasL system. Further studies will be needed to identify the active compounds that confer the anticancer activity of MEGF. Once such compounds are identified, the mechanisms by which they exert their effects can begin to be characterized.

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Effect of Wet Milling on Scum Generation and Solubilization in Batch Ozone Reaction Using Digested Sludge (소화슬러지를 이용한 회분식 오존반응 시 습식분쇄가 스컴 생성과 가용화에 미치는 영향)

  • Hong, Seong-Min;Lee, Dong-Hoon;Kim, Choong-Gon;Shin, Hyun-Gon
    • Journal of the Korea Organic Resources Recycling Association
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    • v.27 no.2
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    • pp.13-18
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    • 2019
  • Sewage sludge treatment is increasing every year due to improvement of living and urbanization. However, interest in anaerobic digestion which is one of the recycling technology. There is anaerobic digestion of increasing due to limitations of ocean dumping and final disposal. But, the limit of anaerobic digestion efficiency due to the advanced treatment of sewage has been limited, and studies for solubilization technology have been actively conducted. Therefore, in this study, we aimed to investigate the variation of generation of scum and the solubilization efficiency in the application of pre-treatment of ozone reaction and the change of properties of digested sludge with wet milling. There are results of VS/TS increased by 4.4% and $SCOD_{cr}/TCOD_{cr}$ increased by 9.4% by wet milling alone. In addition, the increase of the specific surface area due to which the reduction of the particle size of the solid content of the sludge in the ozone reaction caused by wet milling decreased the generation rate of scum at 14.3% and increased VS/TS at 2.1%, compared with the ozone reaction alone. From these results, it is expected that the application of wet milling can be increased the contact efficiency with solids in the sludge during ozone reaction with suppress scum and increase the efficiency of the subsequent process in anaerobic digestion.

A Study on the Establishment of Visual Landscape Impact Factors for Natural Landscape Management (자연경관관리를 위한 시각적 경관영향 요소 설정에 관한 연구)

  • Shin, Min-Ji;Shin, Ji-Hoo
    • Journal of Korean Society of Rural Planning
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    • v.24 no.4
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    • pp.135-146
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    • 2018
  • A Visual landscape planning and management system has been introduced and implemented by each ministry so as to solve the problems of visual landscape destruction due to recognition on the value of natural landscape of beautiful territory and various development projects. At present, this system emphasizes the importance of the visual and perceptual aspect of the landscape however, there is a lack of techniques required for comprehensively predicting, evaluating, and managing it. Furthermore, sustainable landscape management after the completion of development projects has been inadequately carried out, as the focus has been only on consultation in the planning process of the development project in institutional performance. To this end, we presented objective and standardized criteria to predict and judge the effects of development projects on landscapes before project implementation. During the implementation of the development project, the influence of the visual landscape becomes accumulated in the construction progress stage. There is a need to identify the main viewpoints and to examine the continuous changes in the landscape-influencing factors, owing to the remarkable influences on the landscape, such as the change in the topography and the change caused by the artificial structure. During the stage of managing the influence on the visual landscape after the completion of the project, the influence on landscape should be monitored by measuring the change in the continuous landscape-influencing factors and determining the extent to which the actual reduction plan has been implemented. These processes should be performed continuously to maintain the quality of the visual landscape. The change in the landscape caused by the development project is shown to cause relatively greater visual damage than other factors composing the landscape owing to the influence of the artificial factors including the structure or the building. This shows that not only detailed examination of the visual impact before the development project but also continuous management is required during and after the development project. For this purpose, we derived eight landscape-influencing factors including form/shape, line, color, texture, scale/volume, height, skyline, and landscape control point. The proposed considering to be of high utilization in that it has a clear target of the landscape influencing factors.

Knowledge Modeling and Database Construction for Human Biomonitoring Data (인체 바이오모니터링 지식 모델링 및 데이터베이스 구축)

  • Lee, Jangwoo;Yang, Sehee;Lee, Hunjoo
    • Journal of Food Hygiene and Safety
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    • v.35 no.6
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    • pp.607-617
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    • 2020
  • Human bio-monitoring (HBM) data is a very important resource for tracking total exposure and concentrations of a parent chemical or its metabolites in human biomarkers. However, until now, it was difficult to execute the integration of different types of HBM data due to incompatibility problems caused by gaps in study design, chemical description and coding system between different sources in Korea. In this study, we presented a standardized code system and HBM knowledge model (KM) based on relational database modeling methodology. For this purpose, we used 11 raw datasets collected from the Ministry of Food and Drug Safety (MFDS) between 2006 and 2018. We then constructed the HBM database (DB) using a total of 205,491 concentration-related data points for 18,870 participants and 86 chemicals. In addition, we developed a summary report-type statistical analysis program to verify the inputted HBM datasets. This study will contribute to promoting the sustainable creation and versatile utilization of big-data for HBM results at the MFDS.

A Study on the Improvement of Service for the Revitalization of Natural Burial (자연장 활성화를 위한 서비스 개선방안 연구)

  • Lee, Jeung-Sun;Ahn, Jin-Ho
    • Journal of Service Research and Studies
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    • v.13 no.3
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    • pp.70-81
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    • 2023
  • The choice of business method is a necessary decision at the last moment of life, and to this end, we use several criteria. Our funeral methods were dominated by ancestral worship culture and religion, not nature. It is only recently that nature was used as a means from a human perspective, but natural field methods such as consideration for nature and symbiosis with nature have emerged. The recent high public preference for natural fields is today's strong zeitgeist and nature-friendly values. Based on statistics in 2021, Korea's national cremation rate exceeded 92%, and compared to less than 20% of the cremation rate just 20 years ago, our business method has changed rapidly. As the cremation promotion movement and government policies, which began in the early 90s, were systematically developed, the enshrinement facility was established next to us. However, while this was also subject to criticism of national damage, the Jang Act called natural field was introduced into the system in 2008, and about 15 years have passed, but the revitalization of natural field is slower than expected. One of the reasons for the stagnation of development is to forget the basic spirit of the natural field (once you return to the forest), and to think like a graveyard grave. Accordingly, this study aims to identify the background of the introduction and current operation of natural fields and present development measures to improve memorial services to make natural fields loved by the people.

Design and Implementation of Biological Signal Measurement Algorithm for Remote Patient Monitoring based on IoT (IoT기반 원격환자모니터링을 위한 생체신호 측정 알고리즘 설계 및 구현)

  • Jung, Ae-Ran;You, Yong-Min;Lee, Sang-Joon
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.8 no.6
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    • pp.957-966
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    • 2018
  • Recently, the demand for remote patient monitoring based on IoT has been increased due to aging population and an increase in single-person household. A non-contact biological signal measurement system using multiple IR-UWB radars for remote patient monitoring is proposed in this paper. To reduce error signals, a multilayer Subtraction algorithm is applied because when the background subtraction algorithm was applied to the biological signal processing, errors occurred such as voltage noise and staircase phenomenon. Therefore, a multilayer background subtraction algorithm is applied to reduce error occurrence. The multilayer background subtraction algorithm extracts the signal by calculating the amount of change between the previous clutter and the current clutter. In this study, the SVD algorithm is used. We applied the improved multilayer background subtraction algorithm to biological signal measurement and computed the respiration rate through Fast Fourier Transform (FFT). To verify the proposed system using IR-UWB radars and multilayer background subtraction algorithm, the respiration rate was measured. The validity of this study was verified by obtaining a precision of 97.36% as a result of a control experiment with Neulog's attachment type breathing apparatus. The implemented algorithm improves the inconvenience of the existing contact wearable method.