• Journal of Biomedical Engineering Research
• /
• v.43 no.3
• /
• pp.170-176
• /
• 2022

Cell separation from a heterogenous mixture sample is an essential process for downstream analysis in biological, chemical, and clinical applications. This study demonstrates an integrated hybrid device of the viscoelastic focusing in a straight rectangular channel and subsequent size-based separation using acoustophoresis to attain high efficiency and separation tunability. For particle pre-alignment in a viscoelastic fluid, the flow rate higher than 10 μl/min was required. Surface acoustic wave-based lateral migration of particles with different sizes (13 and 27 ㎛) was examined at various applied voltages and flow rate conditions. Therefore, the flow rate of 100 μl/min and the applied voltage of 20 V_pp can be used for size-based particle separation.

• Korean Journal of Oriental Medicine
• /
• v.12 no.2 s.17
• /
• pp.31-45
• /
• 2006

Bioinformatics and medical informatics have moved to make its knowledge more systematically and computationally using ontology. These ontologies help querying ring and analyzing data and used to develop application in biomedical. However, no research about ontology of oriental medical exists. Thus, to maximize the power of transitional knowledge, it is necessary to construct the ontology for oriental medical. This paper compares the ontologies of bio and medic by an objective point of view to guide the construction of oriental medic ontologies.

• Journal of Electrical Engineering and Technology
• /
• v.11 no.5
• /
• pp.1509-1518
• /
• 2016

• Applied Chemistry for Engineering
• /
• v.20 no.5
• /
• pp.517-521
• /
• 2009

In this study, the productivity of bio-ethanol obtained from various brown-algae raw materials was examined. Brown-algae polysaccharide, consisting of alginate and laminaran, is usable for the effective production of bio-ethanol if it is hydrolyzed to monomer unit. The objective of this study is the production of bio-ethanol from brown-algae using a heat-treatment and acid-treatment. Bio-ethanol was produced by Saccharomyces cerevisiae KCCM1129 and Pachysolen tannophilus KCTC 7937 strains. Laminaran japonica was higher than Sagassum fulvellum and Hizikia fusiformis, Laminaran japonica optimum pre-treatment is used to derive the ethanol production of Saccharomyces cerevisiae KCCM1129 and Pachysolen tannophilus KCTC 7937 respectively 9.16 g/L, 9.80 g/L. The maximum output of Sargassum fulvellum and Hizikia fusiformis was very low as 0.22 g/L.

• Journal of Biomedical Engineering Research
• /
• v.33 no.4
• /
• pp.202-206
• /
• 2012

In this study, we developed transdermal direct drug delivery device using micro-needle painlessly. We has fabricated micro-needle that is 130 ${\mu}m$ thickness and 250 ${\mu}m$length with 10 ${\mu}m$ spiral groove for rolling down drug. Head part of micro-needle device is composed of 20ea micro-needles, an on-off valve and a protective cap. Glass bottle for containing drug is connected to head part of micro-needle device. We examined the puncture characteristic testing using porcine skin and drug delivery testing using porcine, rat skin with Indian Ink.

• Proceedings of the KOSOMBE Conference
• /
• v.1997 no.05
• /
• pp.263-266
• /
• 1997

The purpose of this paper is the development of Integrated Bio-signal Management System. (IBMS) using the network. IBMS is the system to manage the medical signals that measured from the each independent medical measurement system module. Each has a LAN Card. We developed the Network Application using Socket Library. Also, we developed the Graphic User Interface software for IBMS using Visual C++ on Windows 95.

• Proceedings of the KOSOMBE Conference
• /
• v.1996 no.05
• /
• pp.151-153
• /
• 1996

The purpose of this paper is the development of Integrated Bio-signal Management System(IBMS) using the network. IBMS is the system to manage the medical signals that measured from the each independent medical measurement system module. Each has a LAN. We developed the file-server network using Novell Netware. Also, we developed the Graphic User Interface software for IBMS using Visual C++ at Windows 3.1.

• Journal of the Korean Institute of Intelligent Systems
• /
• v.15 no.3
• /
• pp.349-354
• /
• 2005

In this paper, we propose a mobile telemedicine system that acquires more easily and analyzes individual's bio-signal using PDA. It is not easy for modern people who live busily, disabled patients, or old people to visit hospital. The major goal of this study is to implement the mobile telemedicine systems that the captured bio-signal from remote hospital or other medical treatment device is transmitted via Bluetooth module in ubiquitous environment, PDA with built-in Bluetooth module receives its data and displays on the screen in various form. By implemented systems, it is possible to compare current bio-signal with historical bio-signal and analyze bio-signal, and it is able to make a self diagnosis and it is available to be examined and treated remote diagnosis by sending stored bio-signal to a medical doctor.

• Transactions of the KSME C: Technology and Education
• /
• v.5 no.1
• /
• pp.23-52
• /
• 2017

Bio-fusion and medical device industry is the multidisciplinary engineering application technology industries, which are fused, such as electricity, electronics, machinery, materials. It aims to improve the quality of human life by using bio-fusion and medical devices, and is an important industry recognition and brand power for the product. However, there is a period that is required from the development of products with technology-dependent industries. Therefore, it is necessary to have continuous effort for industrial investment in research and development at the national level including technical support, institutional support, and human resources.

• Journal of Microbiology and Biotechnology
• /
• v.15 no.1
• /
• pp.206-215
• /
• 2005

Polyhydroxyalkanoates (PHAs) are homo or hetero polyesters of (R)-hydroxyalkanoates accumulated in various microorganisms under growth-limiting condition in the presence of excess carbon source. They have been suggested as biodegradable substitutes for chemically synthesized polymers. Recombinant Escherichia coli is one of the promising host strains for the economical production of PHAs, and has been extensively investigated for the process development. The heterologous PHA biosynthetic pathways have been established through the metabolic engineering and inherent metabolic pathways of E. coli have been redirected to supply PHA precursors. Fermentation strategies for cultivating these recombinant E. coli strains have also been developed for the efficient production of PHAs. Nowadays, short-chain-length (SCL) PHAs are being re-invited due to its improved mechanical properties and possible applications in the biomedical area. In this article, recent advances in the development of metabolically engineered E. coli strains for the enhanced production of SCL-PHAs are reviewed. Also, medical applications of SCL-PHAs are discussed.