• 대한의용생체공학회:의공학회지
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• 제39권1호
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• pp.22-29
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• 2018

Intervertebral disc(IVD) mainly consists of Annulus fibrosus(AF) and Nucleus pulposus(NP), playing a role of distributing a mechanical load on vertebral body. IVD tissue engineering has been developed the methods to achieve anatomic morphology and restoration of biological function. The goal of present study is to identify the possibilities for creating a substitute of IVD the morphology and biological functions are the same as undamaged complete IVD. To fabricate the AF and NP combine biphasic IVD tissue, AF tissue scaffolds have been printed by 3D bio-printing system with natural biomaterials and NP tissues have been prepared by scaffold-free culture system. We evaluated whether the combined structure of 3D printed AF scaffold and scaffold-free NP tissue construct could support the architecture and cell functions as IVD tissue. 3D printed AF scaffolds were printed with 60 degree angle stripe patterned lamella structure(the inner-diameter is 5mm, outer-diameter is 10 mm and height is 3 mm). In the cytotoxicity test, the 3D printed AF scaffold showed good cell compatibility. The results of histological and immunohistochemical staining also showed the newly synthesized collagens and glycosaminoglycans, which are specific makers of AF tissue. And scaffold-free NP tissue actively synthesized glycosaminoglycans and type 2 collagen, which are the major components of NP tissue. When we combined two engineered tissues to realize the IVD, combined biphasic tissues showed a good integration between the two tissues. In conclusion, this study describes the fabrication of Engineered biphasic IVD tissue by using enable techniques of tissue engineering. This fabricated biphasic tissue would be used as a model system for the study of the native IVD tissue. In the future, it may have the potential to replace the damaged IVD in the future.

• Journal of Biosystems Engineering
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• 제41권4호
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• pp.304-312
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• 2016

Purpose: Soil strength has been measured using a cone penetrometer, which is making it difficult to obtain the spatial data required for precision agriculture. Our objectives were to evaluate real-time horizontal soil strength (RHSS) to measure soil strength in real time while moving across the field. Using the RHSS data, the tillage depth was determined, and the power consumption of a tractor and rotavators were compared. Methods: The horizontal soil-strength index (HSSI) obtained by the RHSS was compared with the cone index (CI), which was measured using a cone penetrometer. Comparison analysis in accordance with the measurement depth that increased at 5-cm interval was conducted using kriged maps at six sensing depths. For tillage control and evaluation of the power consumption, the system was installed with a potentiometer for tillage depth, a torque sensor from the rear axle, and a power take-off (PTO) shaft. Results: The HSSI was lower than the CI, but they were the same at 54.81% of the total grids for the 5-cm depth and at 3.85% for the 10-cm depth. In accordance with the recommended tillage map, tillage operations between 0 and 15 cm left 2.3% and 7% residue cover on the soil, and that between 20 and 10 cm covered a wider utilization of 3% and 18.4%, respectively. When the tillage depth was 15 cm, the comparison result of the power requirements between the PTO and rear axle in terms of control performance revealed that the maximum power requirements of the axle and PTO were 44.63 and 23.24 kW, respectively. Conclusions: An HSSI measurement system was evaluated by comparison with the conventional soil strength measurement system (CI) and applied to a tractor to compare the tillage power consumption. Further study is needed on its application to various farm works using a tractor for precision agriculture.

• Advances in nano research
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• 제10권1호
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• pp.77-90
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• 2021

In the present study, novel chitosan coated magnetic magnetite (Fe3O4) nanoparticles were successfully biosynthesized from mushroom, Agaricus campestris, extract. The obtained bio-nanocomposite material was used to investigate ultra-fast and highly efficient for removal of Ni2+ ions in a fixed-bed column. Chitosan was treated as polyelectrolyte complex with Fe3O4 nanoparticles and a Fungal Bio-Nanocomposite Material (FBNM) was derived. The FBNM was characterized by using X-Ray Diffractometer (XRD), Scanning Electron Microscopy-Energy Dispersive X-Ray Spectroscopy (SEM-EDS), Fourier Transform Infrared spectra (FTIR) and Thermogravimetric Analysis (TGA) techniques and under varied experimental conditions. The influence of some important operating conditions including pH, flow rate and initial Ni2+ concentration on the uptake of Ni2+ solution was also optimized using a synthetic water sample. A Central Composite Design (CCD) combined with Response Surface Modeling (RSM) was carried out to maximize Ni2+ removal using FBNM for adsorption process. A regression model was derived using CCD to predict the responses and analysis of variance (ANOVA) and lack of fit test was used to check model adequacy. It was observed that the quadratic model, which was controlled and proposed, was originated from experimental design data. The FBNM maximum adsorption capacity was determined as 59.8 mg g-1. Finally, developed method was applied to soft drinks to determine Ni2+ levels. Reusability of FBNM was tested, and the adsorption and desorption capacities were not affected after eight cycles. The paper suggests that the FBNM is a promising recyclable nanoadsorbent for the removal of Ni2+ from various soft drinks.

• 대한치과보철학회지
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• 제44권4호
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• pp.414-420
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• 2006

Purpose : The purpose of this study is to use finite element analysis to predict the fatigue life of an implant system subjected to fatigue load by mastication (chewing force). The reliability and the stability of implant system can be defined in terms of the fatigue strength. Not only an implant is expensive but also it is almost impossible to correct after it is inserted. From a bio-engineering standpoint, the fatigue strength of the dental implant system must be evaluated by simulation (FEA). Material and Methods Finite element analysis and fatigue test are performed to estimate the fatigue strength of the implant system. Mesh of implant is generated with the actual shape and size. In this paper, the fatigue strength of implant system is estimated. U-fit (T. Strong, Korea, internal type). The stress field in implant is calculated by elastic-plastic finite element analysis. The equivalent fatigue stress, considering the contact and preload stretching of a screw by torque for tightening an abutment, is obtained by means of Sine's method. To evaluate the reliability of the calculated fatigue strength, fatigue test is performed. Results: A comparison of the calculated fatigue strength with experimental data showed the validity and accuracy of the proposed method. The initiation points of the fatigue failure in the implant system exist in the region of high equivalent fatigue stress values. Conclusion: The above proposed method for fatigue life estimation tan be applied to other configurations of the differently designed and improved implant. In order to prove reliability of prototype implant, fatigue test should be executed. The proposed method is economical for the prediction of fatigue life because fatigue testing, which is time consuming and precision-dependent, is not required.

• 에너지공학
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• 제24권1호
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• pp.51-57
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• 2015

본 연구에서는 바이오가스의 공급이 부족한 환경에서 5MW급 바이오 가스터빈을 운전하기 위한 바이오가스와 도시가스의 혼합용 혼합챔버의 성능에 대한 수치해석 및 실증 시험을 수행한 것이다. 혼합챔버의 성능에 대한 수치해석으로 혼합챔버 출구부분에서의 불균일도와 압력강하를 계산하였다. 그 결과, 불균일도는 최소 0.05%에서 최대 0.16%로 이는 99%이상 바이오가스와 도시가스가 혼합되는 것을 의미한다. 압력강하는 입구압력 5bar대비 최소 0.07%에서 0.17%로 0.2%미만으로 나타났다. 이를 통해 현장에서 실증 시험을 수행한 결과 외기온도 $15^{\circ}C$조건에서 바이오가스를 $20.0Nm^3/min$, 도시가스를 $12.0Nm^3/min$ 공급할 경우 5MW급 바이오 가스터빈의 정상적인 운전이 가능함을 확인하였다.

• 설비공학논문집
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• 제26권10호
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• pp.453-459
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• 2014

This paper presents an analysis on the initial ignoring time of SCW type GHX using Mean Square Error method. Line source method is a useful method for estimating the ground thermal conductivity for the vertical type and SCW type GHX in Korea. The line source method for ground thermal conductivity of geothermal in-site test is the basis of linear approximation between the temperature of a borehole and logarithmic time in a GHX. To apply the line source method to the estimation of SCW type GHX, it is necessary to ignore the initial time of data at the stage of a linear approximation. This paper proposed a new initial ignoring time of SCW type GHX among various initial ignoring time at the time for reaching MSE of $0.02^{\circ}C^2$.

• 한국해양바이오학회지
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• 제14권2호
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• pp.76-85
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• 2022

In this study, a biodegradable packaging film was developed using two marine algae, Gelidium amansii, and Sargassum horneri. The chemical properties and microstructure of the developed film were evaluated using field emission scanning electron microscope, Fourier transform infrared spectroscopy, gas chromatography-Mass spectroscopy, and thermogravimetric analysis. Furthermore, the mechanical properties and toxicity of the film were evaluated using the ISO 1924 and IEC 62321 methods, respectively. The biodegradability of the film was evaluated according to ISO 14855-1:2012 method. The film was primarily made of cellulose and had biodegradability that was about 17 times greater than that of PBS, a representative eco-friendly plastic. Moreover, the mechanical properties improved by approximately 40% compared to the seaweed-based film of the previous study. The virulence test revealed that the content of all of the toxic substances listed in IEC62321 was below the measurement limit. An egg carton that can be used in practice was manufactured in accordance with ISO 534, and its applicability was tested using the biodegradable packaging film prepared.

• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.378-378
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• 2006

The preparation, characterization, and bio-testing of biocide incorporated silicone coatings for marine applications have been conducted. Derivatives of the biocide, Triclosan (5-chloro-2-(2, 4-dichlorophenoxy) phenol), were used to covalently attach the biocide moiety to a silicone backbone. The synthetic process allowed for control of the resulting coating's mechanical properties as well as antifouling/fouling release performance in laboratory and ocean site testing. The test results showed significantly reduce macro fouling with sustained fouling release characteristics for the coatings produced.

• 생물환경조절학회지
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• 제27권3호
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• pp.206-212
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• 2018

대부분의 소비자들이 질 좋은 음식을 선호하기 때문에, 농장에서는 소비자들의 욕구를 충족시키기 위해 다양한 시설을 이용하고 있다. 가장 대표적인 시설은 플라스틱 온실과 유리온실이다. 국내의 플라스틱 온실 과 유리 온실의 측고는 3m 내외이다. 결과적으로 작물의 생산성이 제한되고, 이를 해결하기 위해서는 기둥의 높이를 증가시켜 온실의 측고를 높이는 것이다. 온실 기둥상승 장치는 멈춤장치, 공압 실린더 및 수직 부재 등으로 구성된다. 공압 실린더는 안전계수 1.5를 고려하여 직경 160mm와 행정길이 50mm로 설계하였으며, 노즐을 통하여 공기의 압력을 제어하였다. 1행정 시간을 30초 내외로 설계하기 위해서는 $21.5L{\cdot}min^{-1}$ 공기가 필요한 것으로 나타났다. 따라서 노즐의 직경은 0.5mm로 설계하였다. 압력이 0.9 MPa일 때 평균 인상력은 13,805N으로 계산된 값 15,612N에 근접하였다. 현장 시험결과 같은 열의 기둥과 오차가 발생하지 않았으며, 실제 유리 및 플라스틱 온실에 적용 가능한 것으로 판단되었다.

• 한국재료학회지
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• 제31권12호
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• pp.690-696
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• 2021

The purpose of this study is to develop a zirconium-based alloy with low modulus and magnetic susceptibility to prevent the stress-shielding effect and the generation of artifacts. Zr-7Cu-xSn (x = 1, 5, 10, 15 mass%) alloys are prepared by an arc melting process. Microstructure characterization is performed by microscopy and X-ray diffraction. Mechanical properties are evaluated using micro Vickers hardness and compression test. The magnetic susceptibility is evaluated using a SQUID-VSM. The average magnetic susceptibility value of the Zr-7Cu-xSn alloy is 1.176 × 10^-8 cm³g^-1. Corrosion tests of zirconium-based alloys are conducted through polarization test. The average Icorr value of the Zr-7Cu-xSn alloy is 0.1912 ㎂/cm². The elastic modulus value of 14 ~ 18 GPa of the zirconium-based alloy is very similar to the elastic modulus value of 15 ~ 30 GPa of the human bone. Consequently, the Sn added zirconium alloy, Zr-7Cu-xSn, is very interesting and attractive as a biomaterial that reduces the stress-shielding effect caused by differences of elastic modulus between human bone and metallic implants. In addition, this material has the potential to be used in metallic dental implants to effectively eliminate artifacts in MRI images due to low magnetic susceptibility.