• Journal of Ginseng Research
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• v.40 no.4
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• pp.315-324
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• 2016

Background: Biocontrol agents are regarded as promising and environmental friendly approaches as agrochemicals for phytodiseases that cause serious environmental and health problems. Trichoderma species have been widely used in suppression of soil-borne pathogens. In this study, an endophytic fungus, Trichoderma gamsii YIM PH30019, from healthy Panax notoginseng root was investigated for its biocontrol potential. Methods: In vitro detached healthy roots, and pot and field experiments were used to investigate the pathogenicity and biocontrol efficacy of T. gamsii YIM PH30019 to the host plant. The antagonistic mechanisms against test phytopathogens were analyzed using dual culture, scanning electron microscopy, and volatile organic compounds (VOCs). Tolerance to chemical fertilizers was also tested in a series of concentrations. Results: The results indicated that T. gamsii YIM PH30019 was nonpathogenic to the host, presented appreciable biocontrol efficacy, and could tolerate chemical fertilizer concentrations of up to 20%. T. gamsii YIM PH30019 displayed antagonistic activities against the pathogenic fungi of P. notoginseng via production of VOCs. On the basis of gas chromatography-mass spectrometry, VOCs were identified as dimethyl disulfide, dibenzofuran, methanethiol, ketones, etc., which are effective ingredients for antagonistic activity. T. gamsii YIM PH30019 was able to improve the seedlings' emergence and protect P. notoginseng plants from soil-borne disease in the continuous cropping field tests. Conclusion: The results suggest that the endophytic fungus T. gamsii YIM PH30019 may have a good potential as a biological control agent against notoginseng phytodiseases and can provide a clue to further illuminate the interactions between Trichoderma and phytopathogens.

• Journal of Microbiology and Biotechnology
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• v.29 no.9
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• pp.1488-1493
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• 2019

The rising cases of multidrug-resistant Acinetobacter baumannii (Ab) and the lack of effective drugs call for quick attention. Here, based on a Tn7 transposon and Xer/dif system, we constructed a stable, selectable marker-free autoluminescent Ab capable of producing visible light without extra substrates. Utilization of this autoluminescent reporter strain has the potential to reduce the time, effort and costs required for the evaluation of activities of anti-Ab drug candidates in vitro.

• Journal of Environmental Health Sciences
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• v.34 no.1
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• pp.101-107
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• 2008

Bio-filtration utilizes microorganisms fixed to a porous medium to metabolize pollutants present in an air stream. The microorganisms grow in a bio-film on the surface of a medium or are suspended in the water phase surrounding the medium particles. Therefore, bio-filter support media play one of the most important key roles in bio-filtration of gas phase pollutants. To characterize and select the appropriate support media, gas adsorption capacity and microorganism immobilization were investigated in lab-scale experiments for the selected target support media which were compost I (compost from lab-scale process), compost II (compost from municipal facility), bark, wood chip, orchid stone and vermiculite. As odor materials, ammonia and trimethylamine were utilized. From the result of experiments, bark was superior to any other support media tested in adsorption capacity as much as 12.5 mg ammonia per 1 g bark. In trimethylamine adsorption, bark and wood chip showed a remarkable results of 21.1 and 14.1 mg/g respectively. On the other hand, microorganism fixation test determined by the count of nitrogen oxidizing microbes population, the compost II and wood chips showed the best results. Considering the characteristics of materials and the operating condition of the bio-filter, bark, wood chip, and compost II are applicable to the support media of bio-filter when they are appropriately blended on the basis of studying the media pH, packing porosity and moisture contents.

• Journal of Information Technology Services
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• v.19 no.2
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• pp.23-35
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• 2020

The development of digital technology is changing the paradigm of the healthcare industry to preventive and consumer-oriented. The combination of the ICT industry and the bio-healthcare industry is emerging as a core industry in the era of the Fourth Industrial Revolution. The Korean government has also selected the bio-healthcare industry as one of the three key future development industries. In May, the government announced its bio-health industry innovation strategy and set a goal of 300,000 employees. Therefore, analyzing the effects of employment on the related industries of the digital bio-healthcare industry is very important for the establishment of future industrial and technology development policies. The research method restructures the integrated classification of 32 industries into 34, including the digital bio-healthcare industry, using the classification criteria of the government and professional institutions, and then reorganizes the digital bio-healthcare industry into eight industries classified as one industry group. The analysis data was taken from the Bank of Korea's 2019 data. Various trigger coefficients and ripple effects coefficients were rewritten using the analysis method of the Input-output Statistics. The analysis of the results compares the employment-induced effects of the digital bio-healthcare industry and the ripple effects of related industries in production, investment and value-added. In addition, in terms of investment effect, the effects of in-house and related industries were compared. It is hoped that the results of this study will be used to establish employment and industrial policies.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.19 no.5
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• pp.111-117
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• 2020

Centrifugal casting is suitable for producing hollow-products using centrifugal force. Bush type metal bearings are the key parts that facilitate the rotational movement of various machinery. Metal bearings produced by conventional centrifugal casting machines show rotational imbalance. Therefore, after injecting a large amount of material, the product's precision is secured in the secondary processing. Rotational imbalance is caused by the force acting on the rotary disc plate. In order to minimize rotational imbalance, NASTRAN was used for the optimal design and structural analysis. It was concluded that the rotating plate of the conventional centrifugal casting machine should be prevented from tilting. For this purpose, the location & thickness of the stiffeners were obtained through the optimum design. In the conventional centrifugal casting machine, both ends of the product are lower in temperature than the center part, so internal stress occurs. This solves this problem by inserting a heating coil into the rotating plate.

• Proceedings of the Korea Society for Industrial Systems Conference
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• 2007.02a
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• pp.48-52
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• 2007

As huge amount of literature including biological data is being generated after post genome era, it becomes difficult for researcher to find useful knowledge from the biological databases. Bio-text mining and related natural language processing technique are the key issues in the intelligent knowledge retrieval from the biological databases. We propose a bio-text mining technique for the biologists who find Knowledge from the huge literature. At first, web robot is used to extract and transform related literature from remote databases. To improve retrieval speed, we generate an inverted file for keywords in the literature. Then, text mining system is used for extracting given knowledge patterns and keywords. Finally, we construct a grid computing environment to guarantee processing speed in the text mining even for huge literature databases. In the real experiment for 10,000 bio-literatures, the system shows 95% precision and 98% recall.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.7 no.8
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• pp.2010-2026
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• 2013

The combination of biometrics and cryptography gains a lot of attention from both academic and industry community. The noisy biometric measurement makes traditional identity based cryptosystems unusable. Also the extraction of key from biometric information is difficult. In this paper, we propose an efficient biometric identity based signature scheme (Bio-IBS) that makes use of fuzzy extractor to generate the key from a biometric data of user. The component fuzzy extraction is based on error correction code. We also prove that the security of suggested scheme is reduced to computational Diffie-Hellman (CDH) assumption instead of other strong assumptions. Meanwhile, the comparison with existing schemes shows that efficiency of the system is enhanced.

• Archives of Pharmacal Research
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• v.28 no.11
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• pp.1228-1232
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• 2005

Four compounds, including two novel macrolides, were isolated from an endophyte Streptomyces sp. Is9131 of Maytenus hookeri. Spectral data indicated that these compounds were dimeric dinactin (1), dimeric nonactin (2), cyclo-homononactic acid (3), and cyclo-nonactic acid (4). Bioassay results showed that dimeric dinactin had strong antineoplastic activity and antibacterial activity.

• 제어로봇시스템학회:학술대회논문집
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• 2003.10a
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• pp.1933-1938
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• 2003

A covariance matrix is a tool that expresses odometry uncertainty of the wheeled mobile robot. The covariance matrix is a key factor in various localization algorithms such as Kalman filter, topological matching and so on. However it is not easy to acquire an accurate covariance matrix because we do not know the real states of the robot. Up to the authors knowledge, there seems to be no established result on the covariance matrix estimation for the odometry. In this paper, we propose a new method which can estimate the covariance matrix from empirical data. It is based on the PC-method and shows a good estimation ability. The experimental results validate the performance of the proposed method.

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2003.04a
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• pp.31-36
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• 2003

Bio-venture companies have undertaken harsh environment after 2000 bubble corruption. It is unlike to be changed in the near future. The business model of near-term cash flow, financial stability and survival is a key issue to be discussed. The company shall be rearranged to achieve fast recovery from investment and have to show clear and quantitative business model to the investors. Nevertheless, bio-venture should not drop long-term value creation by sacrificing the possibility of emerging technologies. Prior to clarifing agro-bioventure business model, GMO strategy should have broad supports from stakeholders. The interests and worries of stakeholders are discussed and SWOT is analyzed. For sustainable economy of future, new technology continuously should be invested to fit ROI model of genomics-based GMO developments. Hybrid of products ${\varepsilon}$ technologies may be one of the favorites in this stormy season.