• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2011년도 춘계학술발표회
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• pp.372-373
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• 2011

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2011년도 추계학술발표회
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• pp.316-317
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• 2011

• 한국자원식물학회지
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• 제29권6호
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• pp.690-698
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• 2016

Various bioactive substances are found in mistletoe, including viscumneoside III (1) and homoflavoyadorinin B (2), both which inhibit tyrosinase. These two compounds are mainly found in the EtOAc fraction of the mistletoe extract and demonstrate higher rates of tyrosinase inhibition than ascorbic acid, which was used as a control. Our results suggest that mistletoe extracts can be utilized in skin whitening cosmetics.

• 한국융합학회논문지
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• 제6권6호
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• pp.255-261
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• 2015

본 연구의 목적은 대학생의 생명의료윤리 특성과 자존감과의 상관관계를 알아보고, 보건계열과 비보건계열 대학생의 생명윤리의식 간에 차이를 비교하는 것이다. 연구대상자는 일개 대학의 보건계열과 비보건계열을 포함한 대학생 651명으로 생명윤리의식과 자존감에 대해 2015년 5월 2주간 조사하였다. 그 결과 자존감은 생명의료윤리인식과 유의한 상관관계가 있는 것으로 나타났으며, 자존감이 높은 대학생이 생명의료윤리를 중요하게 생각하는 것으로 나타났다. 그러나 보건계열과 비보건계열의 생명의료윤리 인식을 비교한 결과 생명공학을 제외한 안락사, 뇌사 등에는 유의한 차이를 보이지 않았다.

• 전자공학회논문지
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• 제51권1호
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• pp.233-240
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• 2014

최근 노인인구의 증가하는 추세에 따라 만성질환자의 수도 증가하고 있으며 건강 관리문제가 중요하게 대두되고 있다. 본 논문에서는 만성질환자의 건강관리를 위한 유헬스케어 시스템을 구현하고자 한다. 제안한 만성 질환자 관리 시스템은 생체 계측 시스템과 모바일 게이트웨이 그리고 의료정보 관리 서버 그리고 클라이언트로 구성되면 생체 신호는 심전도, 혈압, 혈당, 산소포화도 등의 모듈로 구성하였다. 혈당체크는 이동성을 고려하여 생체계측 시스템으로 전송하는 방법과 게이트웨이로 전송하는 방법 중 선택할 수 있도록 구현하였다. 제안한 생체 계측 시스템과 모바일 게이트웨이는 블루투스 통신을 이용하여 전송한다. 전송된 생체 데이터는 모바일 게이트웨이에서 건강상태를 감시하거나 네트워크 서버로 전송하고 클라이언트을 이용하여 검색 할 수 있도록 하였다. 만성질환자의 생체신호 감시 시스템을 구현함으로서 측정되어진 생체 데이터를 모니터링하여 현재의 건강상태를 확인할 수 있었으며 모바일 환경에서 다양한 생체신호를 전송하였다.

• Journal of the Optical Society of Korea
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• 제17권1호
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• pp.91-96
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• 2013

We report a method for optical monitoring of tumors in an animal model using optical coherence tomography (OCT). In a spectral domain OCT system, a superluminescent diode light source with a full width of 66 nm at half maximum and peak wavelength of 950 nm was used to take images having an axial resolution of 6.8 ${\mu}m$. Cancer cells of PC-3 were cultured and inoculated into the hypodermis of auricle tissues in BALB/c nude mice. We observed tumor formation and growth at the injection region of cancer cells in vivo and obtained the images of tumor mass center and sparse circumferences. On the $5^{th}$ day from an inoculation of cancer cells, histological images of the tumor region using cross-sectional slicing and dye staining of specimens were taken in order to confirm the correlation with the high resolution OCT images. The OCT image of tumor mass compared with normal tissues was analyzed using its A-scan data so as to obtain a tissue attenuation rate which increases according to tumor growth.

• Fisheries and Aquatic Sciences
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• 제17권3호
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• pp.275-290
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• 2014

The marine ecosystem represents a vast and dynamic array of bio-resources attributed with its huge diversity and considered as potential untapped reservoirs for the development of functional foods for future health markets. Basically, marine microorganisms, sponges, algae, invertebrates such as crustaceans and mollusks along with marine fish species can be considered as marine bio-resources, which can be utilized to obtain different health benefits for humans, directly or after processing. Most of the bio-molecular components, such as lipids and proteins from these marine bio-resources, which can be extracted in large scale using the modern and advanced biotechnological approaches, are suitable drug candidates for the pharmaceutical industry as well as functional food ingredients for the food industry. Moreover, the furtherance of high throughput molecular biological techniques has already been incorporated with identification, mining and extraction of molecular components from marine bio-resources. In this review, potential marine bio-resources with respect to their extractable bio-molecules were described in details, while explaining the present and prospective methods of identification and extraction, which are integrated with advanced techniques in modern biotechnology. In addition, this provides an overview of future trends in marine biotechnology.

• The Korean Journal of Physiology and Pharmacology
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• 제23권5호
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• pp.335-344
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• 2019

Obesity causes inflammation and impairs thermogenic functions in brown adipose tissue (BAT). The adipokine lipocalin 2 (LCN2) has been implicated in inflammation and obesity. Herein, we investigated the protective effects of caloric restriction (CR) on LCN2-mediated inflammation and oxidative stress in the BAT of high-fat diet (HFD)-fed mice. Mice were fed a HFD for 20 weeks and then either continued on the HFD or subjected to CR for the next 12 weeks. CR led to the browning of the white fat-like phenotype in HFD-fed mice. Increased expressions of LCN2 and its receptor in the BAT of HFD-fed mice were significantly attenuated by CR. Additionally, HFD+CR-fed mice had fewer neutrophils and macrophages expressing LCN2 and iron-positive cells than HFD-fed mice. Further, oxidative stress and mitochondrial fission induced by a HFD were also significantly attenuated by CR. Our findings indicate that the protective effects of CR on inflammation and oxidative stress in the BAT of obese mice may be associated with regulation of LCN2.

• Asian-Australasian Journal of Animal Sciences
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• 제31권12호
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• pp.1974-1979
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• 2018

Objective: This study compared fatty acid compositions and antioxidant activities of high-preference cuts (loin, tenderloin, and rib) and low-preference cuts (brisket, topside, and shank) of Hanwoo (Bos taurus coreanae) cows to obtain potentially useful information for promoting the consumption of various low-preference cuts. Methods: Individual 500 g samples of fresh beef were collected from each of the six cuts from 10 Hanwoo cows (quality grade 1) and immediately freeze-dried. The dried samples were evaluated for fatty acid composition, free radical scavenging activities (hydroxyl, alkyl, and 2, 2'-diphenyl-1-picrylhydrazyl [DPPH] radical), and antioxidative enzyme activities (glutathione peroxidase [GPx], glutathione-S-transferase [GST], and superoxide dismutase [SOD]). Results: The percentages of total polyunsaturated fatty acids were significantly higher in low-preference cuts than in high-preference cuts (p<0.05). Hydroxyl, alkyl, and DPPH radical scavenging activities were significantly higher in low-preference cuts than in high-preference cuts (p<0.05). In addition, the activities of antioxidant enzymes, such as GPx, GST, and SOD, were significantly higher in low-preference cuts compared with high-preference cuts (p<0.05). Conclusion: These results may influence consumers to include more low-preference cuts in their selections based on the nutritional facts, which could help to balance the beef market in South Korea.

• 한국자원식물학회지
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• 제27권3호
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• pp.256-262
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• 2014

Viscum album var. coloratum (mistletoe) is considered as one of the endangered plant species in Korea. Our objective is to restore its population and multiplication of plant by ex situ method. In this research we explored the maximum germination (in vitro) of freshly harvested and stored seeds of mistletoe collected in different time intervals. Ex vitro germination after artificial inoculation on the branches of Prunus mume in different physiological conditions was also monitored. The research revealed that the lately harvested seeds (Feb. and March 2014) were superior over early harvested seeds (Nov. 2013 and Jan. 2014) of mistletoe due to the higher percentage of germination (above 93%). According to the data, it is also revealed that the survival and germination rate of mistletoe seeds decreased with the increase in storage duration. In ex vitro germination, the fluctuated temperature of a glass house in natural condition enhanced (four fold) the rate of germination on the branches of Prunus mume than the constant temperature condition in the glass house.