• Translational and Clinical Pharmacology
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• v.25 no.2
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• pp.67-73
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• 2017

Glimepiride, a third generation sulfonylurea, is an antihyperglycemic agent widely used to treat type 2 diabetes mellitus. In this study, an untargeted urinary metabolomic analysis was performed to identify endogenous metabolites affected by glimepiride administration. Urine samples of twelve healthy male volunteers were collected before and after administration of 2 mg glimepiride. These samples were analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS), and then subjected to multivariate data analysis including principal component analysis and orthogonal partial least squares discriminant analysis. Through this metabolomic profiling, we identified several endogenous metabolites such as adenosine 3', 5'-cyclic monophosphate (cAMP), quercetin, tyramine, and urocanic acid, which exhibit significant metabolomic changes between pre- and posturine samples. Among these, cAMP, which is known to be related to insulin secretion, was the most significantly altered metabolite following glimepiride administration. In addition, the pathway analysis showed that purine, tyrosine, and histidine metabolism was affected by pharmacological responses to glimepiride. Together, the results suggest that the pharmacometabolomic approach, based on LC-MS/MS, is useful in understanding the alterations in biochemical pathways associated with glimepiride action.

• Journal of Environmental Impact Assessment
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• v.23 no.1
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• pp.11-17
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• 2014

Since the Renewable Portfolio Standard (RPS) would be started in 2012, the use of renewable energy should be 11% of total energy use including bio-fuel in 2030. The economic efficiency for renewable energy in B power plant was considered with the bio-diesel, wind power and solar power. The Net Present Value (NPV) and Benefit/Cost Ratio(BC) were used for the economic efficiency with the cost and benefit analysis. In case of bio-diesel, the cost resulted from the fuel conversion and the benefit would be created with trade and environmental improvement. With regard to wind power and solar power, the construction cost would be required and benefit factors would be same as the bio-diesel. The wind power was the best of economic efficiency of renewable energy as the results of NPV and BC ratio. Whereas, the market of wind power was very popular and the techniques of wind power has been developing rapidly.

• Journal of the Korean Society of Industry Convergence
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• v.20 no.1
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• pp.27-33
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• 2017

An agriculture machines are subjected to different loads conditions. Due to this loads variations there will be certain deformations and stress which affect the performance of the electric vehicle in adverse manner. The purpose of this paper is to analyze the total deformation and stress of the electric farm vehicle middle frame based on the finite element method. The proposed electric farm vehicle has lifting and dumping capability. Therefore, in this research four operational condition such as normal condition, dumping condition, lifting condition, and lifting-dumping condition was analyzed. In this research, the design for whole frame structure is elaborated. According to the mechanical characteristics of the frame, materials are selected and manufacturability requirements are limited. Based on ANSYS 15 software, the finite element model of electric farm vehicle is established to carry out static analysis on full-loaded conditions. The simulation results shows that the proposed design meet the strength requirements and displacement requirements. The maximum deformation 0.53611 mm and maximum stress 30.163 MPa occurred at lifting-dumping condition.

• Analytical Science and Technology
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• v.16 no.1
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• pp.25-31
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• 2003

Chromium(III) picolinate, a highly bioavailable compound, is known to be used for supplementing essential chromium(III) to human beings and animals. Two different methods were used to synthesize chromium(III) picolinate. The synthetic products were characterized by elemental analysis, FTI-IR, high performance liquid chromatography (HPLC) and MALDI-MS.

• Advances in nano research
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• v.10 no.1
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• pp.71-76
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• 2021

Synthesis of nanoparticles using green technology using plants is gaining significant attention as it is an environmentally friendly substitute to conventional physical and chemical methods. The present study was focused on the chemical and green synthesis of Iron Oxide nanoparticles from ferric chloride. The green synthesis was achieved by utilizing the bio components of Hibiscus rosa-sinensis. The Fe3O4 nanoparticles with the size range of 87-400 nm were synthesized by wet chemical reduction technique which are unstable, prone to aggregation while in green synthesis the phytochemicals present in the leaf extract acts as the capping as well as the reducing agent thus the green synthesized iron (III) oxide nanoparticles were naturally stabilized, spherical shaped and are in the size range of 2-80 nm. The results of both the protocols are compared and presented briefly.

• Korean Journal of Plant Taxonomy
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• v.52 no.2
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• pp.123-126
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• 2022

Hibiscus sabdariffa L., (roselle) in the Malvaceae family is an erect subshrub known to be native to India and Malaysia. It is widely used as a food or tea material around the world, and its therapeutic effects have been widely studied. In this study, the sequencing of the complete chloroplast genome of H. sabdariffa was carried out. The result indicates a genome size of 162,428 bp, which is composed of a large single copy of 90,327 bp, two inverted repeats of 26,242 bp each, and a small single copy of 19,617 bp. Overall, a total of 131 genes were predicted, including 86 coding sequences, 37 tRNAs, and 8 rRNAs. According to a phylogenic analysis, it was clearly distinguished from outgroups such as other species of the genus Hibiscus used in the analysis.

• Proceedings of the Korean Society for Bio-Environment Control Conference
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• 2003.04a
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• pp.181-190
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• 2003

컴퓨터 시각장치에 의한 3차원 정보를 이용한 연구현황으로서는 최근에 많이 연구되어지고 있으며, 그 중에서 가장 일반적인 방법으로 사람의 눈과 비슷한 구조를 가진 스테레오 시각을 이용한다. 한 대의 카메라를 통해 얻어지는 3차원 형상 정보는 3차원 대상체가 2차원 평면상에 투사되어 얻어진 정보이므로 대상체가 갖는 3차원 공간 정보를 얻기 위한 접근법이 필요하다. (중략)

• Elastomers and Composites
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• v.59 no.2
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• pp.51-63
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• 2024

Polypropylene (PP) is a commodity plastic that is widely used owing to its cost-effectiveness, lightweight nature, easy processability, and outstanding chemical and thermomechanical characteristics. However, the imperative to address energy and environmental crises has spurred global initiatives toward a circular economy, necessitating sustainable alternatives to traditional fossil-fuel-derived plastics. In this study, we conducted a series of comparative investigations of bio-based polypropylene (bio-PP) blends with current PP of the same and different grades. An extrusion-based processing methodology was employed for the bio-PP composites. Talc was used as an active filler for the preparation of the composites. A comparative analysis with the current petroleum-based PP indicated that the thermal properties and tensile characteristics of the bio-PP blends and composites remained largely unaltered, signifying the feasibility of bio-PP as a potential substitute for the current PP. To achieve a higher Young's modulus, elongation at break (EAB), and melt flow index (MFI), we prepared different composites of PP of different grades and bio-PP with varying talc contents. Interestingly, at higher biomass contents, the composites exhibited higher MFI and EAB values with comparable Young's moduli. Notably, the impact strengths of the composites with various biomass and talc contents remained unaltered. In-depth investigations through surface analysis confirmed the uniform dispersion of talc within the composite matrix. Furthermore, the moldability of the bio-PP composites was substantiated by comprehensive rheological property assessments encompassing shear rate and shear viscosity. Thus, from these outcomes, the fabricated bio-PP-based composites could be an alternative to petroleum-based PP composites for sustainable automobile applications.

• The Journal of Fisheries Business Administration
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• v.40 no.3
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• pp.127-146
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• 2009

This study is to estimate the factor weights of the reasons for decreases in marine fishery resources using the Analytical Hierarchy Process. Furthermore, it classifies 20 fishes under a fishery resource recovery plan into various groups of fishes according to these factor weights using the non-hierarchial cluster analysis. The factors of decreases in marine fishery resources are identified as bio-ecological, technology-system, economic-business, and fishing village-society factors. Two of the most important factors of decreases in resource are turned out to be the economic-business and bio-ecological factors, estimated as 31% and 30% respectively. The technology-system and fishing village-society factors are estimated as 21% and 18% respectively. The study utilizes non-hierarchical cluster analysis in order to classify 20 fishes into 2, 3, and 4 groups. K-means cluster analysis is applied for grouping in conjunction with ANOVA to identify statistical differences in factors. Once again, the economic-business and bio-economic factors play main role in grouping 2-groups of fishes case. The third group of fishes in addition to the previous 2 groups of fishes appears as those 4 factors of decrease evenly play about the same role at a 3-groups of fishes case. Finally, the economic-business and bio-economic factors are turned out to be evenly important in the 4th group once there are 4-groups of fishes.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37 no.4C
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• pp.283-289
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• 2012

Web-based physiological signal monitoring system can provide appropriate healthcare services to transmit bio-signal processing, analysis of bulk in medical centers. Therefore, we constructed a design of system to analyze effect of cardiac associated auricular acupuncture reflexology based on physiological signals. System to analyze effect cardiac associated auricular acupuncture reflexology, which carried out analysis and measurement of bio-signal to apply cardiac-related biometrics input in biometric image and voice signal. In addition, we also confirmed through statistical analysis actual home healthcare system to performance evaluation of system on subjects 20.