• Title/Summary/Keyword: Bio-accumulation

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Adenocarcinoma of the parotid gland with calcification (석회화를 수반한 이하선내 선양암종)

  • Song Haeng-Eun;Koh Kwang-Joon
    • Imaging Science in Dentistry
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    • v.32 no.1
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    • pp.55-59
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    • 2002
  • A 78-year-old woman was referred to Chonbuk National University Dental Hospital complaining of facial palsy and palpable mass on the right parotid gland area. Clinical examination showed non-specific findings of the intraoral region, but showed asymmetrical facial appearance. Panoramic view showed a large amorphous calcified mass on the posterior to the mandibular ramus and thin cortical plate of the posterior ramus. Sialogram showed constriction of the main duct and no further filling of striated, intercalated ducts and parenchymal areas. CT scans demonstrated an irregular, infiltrating mass with slight enhancement in the right parotid gland. The mass showed necrotic areas and calcifications. Bone scan showed marked accumulation of /sup 99m/Tc-MDP on the right posterior maxilla. Microscopic findings demonstrated the minimal morphologic alterations and rare mitotic figures within tumor cells, and diagnosed as adenocarcinoma (NOS, Grade II). This report could be aid in the diagnosis of calcified lesions of the salivary gland.

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Visualization of Electro-osmotic Flow Instability in a T-shape Microchannel (T자형 마이크로 채널 내부 전기삼투 유동의 불안정성 가시화)

  • Han, Su-Dong;Lee, Sang-Joon
    • Journal of the Korean Society of Visualization
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    • v.3 no.2
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    • pp.45-50
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    • 2005
  • Electro-osmotic flow (EOF) instability in a microchannel has been experimentally investigated using a micro-PIV system. The micro-PIV system consisting of a two-head Nd:Yag laser and cooled CCD camera was used to measure instantaneous velocity fields and vorticity contours of the EOF instability in a T-shape glass microchannel. The electrokinetic flow instability occurs in the presence of electric conductivity gradients. Charge accumulation at the interface of conductivity gradients leads to electric body forces, driving the coupled flow and electric field into an unstable dynamics. The threshold electric field above which the flow becomes unstable and rapid mixing occurs is about 1000V/cm. As the electric field increases, the flow pattern becomes unstable and vortical motion is enhanced. This kind of instability is a key factor limiting the robust performance of complex electrokinetic bio-analytical devices, but can also be used for rapid mixing and effective flow control fer micro-scale bio-chips.

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Growth retardants stimulate guggulsterone production in the presence of fungal elicitor in fed-batch cultures of Commiphora wightii

  • Suthar, Satish;Ramawat, K.G.
    • Plant Biotechnology Reports
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    • v.4 no.1
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    • pp.9-13
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    • 2010
  • Guggulsterone, a hypolipidemic natural agent, is produced in resin canals of the plant Commiphora wightii. In this study, the stimulatory effects of growth retardants [ALAR (N,N-dimethylaminosuccinamic acid) and CCC (chlormequat chloride)] and fungal elicitor on guggulsterone accumulation in cell cultures of C. wightii are reported. CCC at $1\;mg\;l^{-1}$ enhanced guggulsterone content (${\sim}123\;{\mu}g\;l^{-1})$ when added on the fifth day after inoculation, while ALAR at $2.5\;{\mu}g\;l^{-1}$ increased guggulsterone content (${\sim}116\;{\mu}g\;l^{-1}$) when added on the tenth day. In a two-stage fed-batch process, combined treatment with fungal elicitor and growth retardant caused a significant increase (${\sim}353\;{\mu}g\;l^{-1}$) in guggulsterone content in cell cultures after 17 days of growth. This represents an approximately fivefold increase over the guggulsterone contents in initial cultures of this plant.

Elicitor-induced accumulation of stilbenes in cell suspension cultures of Cayratia trifolia (L.) Domin

  • Roat, Chetana;Ramawat, K.G.
    • Plant Biotechnology Reports
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    • v.3 no.2
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    • pp.135-138
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    • 2009
  • Cell cultures of Cayratia trifolia (Vitaceae), a tropical lianas, were maintained in Murashige and Skoog's medium containing $0.25mg\;1^{-1}$ NAA, $0.2mg\;1^{-1}$ kinetin and casein hydrolysate $250mg\;1^{-1}$. Cell suspension cultures of C. trifolia accumulate stilbenes (piceid, resveratrol, viniferin, ampelopsin), which on elicitation by any of $500{\mu}M$ salicylic acid, $100{\mu}M$ methyl jasmonate, $500{\mu}M$ ethrel and $500mg\;1^{-1}$ yeast extract, added on the 7th day, were enhanced by 3- to 6-fold ($5-11mg\;1^{-1}$) by the 15th day.

Effect of Cultural Environments and Nitrogen Fertilization Levels on the Anthocyanin Accumulation of Purple-fleshed Potato (Solanum tuberosum L.) Variety Jasim (재배환경 및 질소시비량이 자주색 감자 '자심'의 안토시아닌 색소 축적에 미치는 영향)

  • Jeong Jin-Ceol;Chang Dong-Chil;Yoon Young-Ho;Park Chun-Su;Kim Sung-Yeol
    • Journal of Bio-Environment Control
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    • v.15 no.2
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    • pp.204-210
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    • 2006
  • The purple color in flesh of 'Jasim' potato (Solanum tuberosum L.) tubers is due to an accumulation of anthocyanin. The experiment was conducted to determine what is the key factor among cultural environments that affect the accumulation of anthocyanin in 'Jasim' potato tubers, and the effect of nitrogen fertilization levels on that. Through analysis of anthocyanin content of purple-fleshed tubers produced under the different cultural environments of three localities and two planting dates, we determined that lower temperature during 30days before harvesting resulted in higher anthocyanin accumulation of 'Jasim' potato tubers. In the experiment of different level of nitrogen fertilization, 'Jasim' potato tubers produced in highland (Daegualryeong) showed higher content of anthocyanin in the treatment of recommended level than in treatment of lower or higher level as compared with the recommended level. However, significant difference of anthocyanin content among different nitrogen fertilization levels was not observed in lowland (Gangnung). These results suggest that the selection of locality or cropping system and the optimal fertilization management are very important factors for production of higher pigmented tubers in purple-fleshed potato.

Anti-obesity effects of black ginseng extract in high fat diet-fed mice

  • Lee, Mi Ra;Kim, Byung Chan;Kim, Ran;Oh, Hyun In;Kim, Hyun Kyoung;Choi, Kang Ju;Sung, Chang Keun
    • Journal of Ginseng Research
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    • v.37 no.3
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    • pp.308-314
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    • 2013
  • Black ginseng is produced by a repeated steaming process. The aim of this study was to investigate the anti-obesity effects of black ginseng ethanol extract (BG-EE) in high fat (HF) diet-fed mice. Two groups were fed either a normal control (NC) diet or a HF diet (45% kcal fat). The other three groups were given a HF diet supplemented with 1% BG-EE, 3% BG-EE, and 5% BG-EE for 12 wk. The anti-obesity effects of the BG-EE supplement on body weight, the development of fat mass, and lipid mechanisms were assessed in obese mice. HF-induced hyperlipidemia, fat accumulation in the liver, and white adipose tissues were reduced after BG-EE supplementation. Total fecal weight and the amount of fecal fat excretion also were increased after BG-EE supplementation. These results suggest that BG-EE may be useful to ameliorate HF-induced obesity through the strong inhibition of fat digestion.

Lindera erythrocarpa Makino extract reduces obesity induced by high-fat diet in rats

  • Ahn, Mee-Jung;Yang, Won-Jun;Kang, So-Hi;Kang, Min-Chul;Ko, Ryeo-Kyeong;Kim, Gi-Ok;Shin, Tae-Kyun
    • Advances in Traditional Medicine
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    • v.10 no.4
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    • pp.288-293
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    • 2010
  • Lindera erythrocarpa Makino (LE) is widely distributed on Jeju Island, where it has been used for various traditional therapies. Effects of a crude extract of LE were examined in rats with obesity induced by a high-fat diet (HFD). Anti-obesity effects were followed in rats receiving orally administered vehicle, 100mg/kg extract, or 250 mg/kg LE extract, for 56 days. LE extract (250 mg/kg) suppressed increases in body weight and epididymal fat, with amelioration of fatty changes in the liver. Additionally, serum levels of alanine aminotransferase, aspartate aminotransferase, and total cholesterol were significantly decreased compared with those of vehicle-treated groups (p < 0.05). These results suggest that oral administration of LE extract reduced rat obesity induced by HFD, possibly through the reduction of fat accumulation.

Diallel Analysis for Rice Allelopathic Potential against Barnyardgrass Assessed in Field Condition

  • Junaedi, Ahmad;Lee, Sang Bok;Chung, Ill Min;Kim, Kwang Ho
    • Korean Journal of Breeding Science
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    • v.40 no.1
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    • pp.8-14
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    • 2008
  • A complete diallel cross was performed to determine the inheritance of allelopathic potential and combining ability of six rice germplasm that showed different level of allelopathic potential against barnyardgrass. Parents and F1 of 30 crosses were assessed for allelophatic potential in field condition. Barnyardgrass (Echinochloa crus-galli (L.) Beauv. var. frumentaceae) was used for rice allelopathic potential indicator which was observed in height and shoot dry weight, then suppression percentage were calculated by comparing to barnyardgrass grown in control plot (no rice). It was found that general combining ability showed no significant effect, whereas specific combining ability and reciprocal effect were significant. Variance analysis confirmed that genetic control of allelopathic potential in rice against barnyardgrass was mostly directed by dominance gene effect. The dominant genes were associated with high allelopathic potential and recessive genes were associated with low allelopathic potential. Heritability in broad sense for barnyardgrass dry weight suppression was around 41%; whereas for barnyardgrass height suppression was 51%. However, heritability in narrow sense was very low. The finding suggests that accumulation of genes associated with allelopathic potential would be a strategy to develop promising varieties in reference with the specific combining ability of cross combinations.