• 제목/요약/키워드: Bio-Function

검색결과 780건 처리시간 0.031초

메타프로테오믹스의 미생물생태학적 응용 (Metaproteomics in Microbial Ecology)

  • 김종식;우정희;김준태;박년호;김충곤
    • 미생물학회지
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    • 제46권1호
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    • pp.1-8
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    • 2010
  • 미생물 군집과 기능연구를 위한 최근의 새로운 분석기술의 발전은 다양한 유전 관련 정보를 제공해왔다. mRNA를 포함하는 핵산을 기초로 한 연구를 뛰어넘어서 메타프로테오믹스는 미생물 군집의 유전형 및 표현형의 특징적인 정보를 보다 정교하게 제공할 수 있다. 이미 서로 다른 미생물 생태계인 해수, 인간의 배설물, 활성 슬러지, 산성 광산 폐수 생물막, 토양 등에 메타프로테오믹스 기술이 유용하게 사용되었다. 이들 연구는 여러 측면에서 상당히 다르지만 미생물 군집의 구조, 기능, 생리, 상호관계, 생태, 진화적 측면을 결정적으로 상호 연결한다는 것을 밝혀냈다. 본 총설은 메타프로테오믹스에 대한 현재까지의 가장 최신의 정보를 요약하여 제공함으로써 메타프로테오믹스에 대한 정확한 이해와 활용을 통해 다방면의 메타프로테오믹스가 가능하도록 하고자 하였다.

Analysis of the Cutting Shape as a Function of Feed Rate and Cutting Speed of Korean and Japanese Combines

  • Jin, Byung-Ok;Lee, Min-Ho;Jo, Jin-Seok;Jung, Ho-Jun;Kim, Chi-Ho;Kim, Hyeon-Tae
    • Journal of Biosystems Engineering
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    • 제42권2호
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    • pp.80-85
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    • 2017
  • Purpose: In this study, we attempted to analyze, by using a high-speed camera, the cutting shape as a function of cutting speed and feed rate. We compared the differences in cutting shape between domestic and foreign combines. Methods: Experiments were performed using plastic straws, and the results of two combine cutting blades, one from the Daedong Industry and one from Kuboda, were compared. The quality and performances of cutting were measured at three cutting positions: center and 68 cm to the left and right of the center. The feed rates were 0.6 m/s, 1.1 m/s, 1.6 m/s, and the cutting speeds were 600 RPM, 990 RPM, 1,380 RPM. For each speed, the cutting shape was measured three times, and the entire procedure was also repeated three times. Results: In the experiments, the domestic cutting blade achieved better results than the Japanese cutting blade. These results were obtained by studying the combination of feed rate and cutting speed, with the domestic combine attaining approximately 80% performance of the Japanese combine. We believe that additional data analysis is required, obtained from field experiments. Conclusions: The domestic cutting knives achieved better results than the Japanese cutting knives. These results are estimated from experiments conducted with different feed rates and cutting speeds; an in-depth analysis will require experiments in the real field with actual combines and a combination of multiple variables. Repeating the investigation on the length differences, broken and cut angle with various combinations of feed rate and cutting speed, will surely help to find the optimal cutting speed.

AN IMPROVED ALGORITHM FOR RNA SECONDARY STRUCTURE PREDICTION

  • Namsrai Oyun-Erdene;Jung Kwang Su;Kim Sunshin;Ryu Keun Ho
    • 대한원격탐사학회:학술대회논문집
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    • 대한원격탐사학회 2005년도 Proceedings of ISRS 2005
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    • pp.280-282
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    • 2005
  • A ribonucleic acid (RNA) is one of the two types of nucleic acids found in living organisms. An RNA molecule represents a long chain of monomers called nucleotides. The sequence of nucleotides of an RNA molecule constitutes its primary structure, and the pattern of pairing between nucleotides determines the secondary structure of an RNA. Non-coding RNA genes produce transcripts that exert their function without ever producing proteins. Predicting the secondary structure of non-coding RNAs is very important for understanding their functions. We focus on Nussinov's algorithm as useful techniques for predicting RNA secondary structures. We introduce a new traceback matrix and scoring table to improve above algorithm. And the improved algorithm provides better levels of performance than the originals.

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삼중 주기적 최소곡면을 이용한 조직공학을 위한 생체모사 스캐폴드의 컴퓨터응용 설계 및 제작 (Computer-aided Design and Fabrication of Bio-mimetic Scaffold for Tissue Engineering Using the Triply Periodic Minimal Surface)

  • 유동진
    • 한국정밀공학회지
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    • 제28권7호
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    • pp.834-850
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    • 2011
  • In this paper, a novel tissue engineering scaffold design method based on triply periodic minimal surface (TPMS) is proposed. After generating the hexahedral elements for a 3D anatomical shape using the distance field algorithm, the unit cell libraries composed of triply periodic minimal surfaces are mapped into the subdivided hexahedral elements using the shape function widely used in the finite element method. In addition, a heterogeneous implicit solid representation method is introduced to design a 3D (Three-dimensional) bio-mimetic scaffold for tissue engineering from a sequence of computed tomography (CT) medical image data. CT image of a human spine bone is used as the case study for designing a 3D bio-mimetic scaffold model from CT image data.

Multi-modal Authentication Using Score Fusion of ECG and Fingerprints

  • Kwon, Young-Bin;Kim, Jason
    • Journal of information and communication convergence engineering
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    • 제18권2호
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    • pp.132-146
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    • 2020
  • Biometric technologies have become widely available in many different fields. However, biometric technologies using existing physical features such as fingerprints, facial features, irises, and veins must consider forgery and alterations targeting them through fraudulent physical characteristics such as fake fingerprints. Thus, a trend toward next-generation biometric technologies using behavioral biometrics of a living person, such as bio-signals and walking characteristics, has emerged. Accordingly, in this study, we developed a bio-signal authentication algorithm using electrocardiogram (ECG) signals, which are the most uniquely identifiable form of bio-signal available. When using ECG signals with our system, the personal identification and authentication accuracy are approximately 90% during a state of rest. When using fingerprints alone, the equal error rate (EER) is 0.243%; however, when fusing the scores of both the ECG signal and fingerprints, the EER decreases to 0.113% on average. In addition, as a function of detecting a presentation attack on a mobile phone, a method for rejecting a transaction when a fake fingerprint is applied was successfully implemented.

Substrate-free Biosensing using Brownian Rotation of Bio-conjugated Magnetic Nanoparticles

  • Chung Seok-Hwan;Hoffmann Axel;Chen, Liaohai;Sun, Shouheng;Guslienko Konstantin;Grimsditch Marcos;Bader Samuel D.
    • Journal of Magnetics
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    • 제11권4호
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    • pp.189-194
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    • 2006
  • The recent development of bio-conjugated magnetic nanoparticles offers many opportunities for applications in the field of biomedicine. In particular, the use of magnetic nanoparticles for biosensing has generated widespread research efforts following the progress of various magnetic field sensors. Here we demonstrate substrate-free biosensing approaches based on the Brownian rotation of ferromagnetic nanoparticles suspended in liquids. The signal transduction is through the measurement of the magnetic ac susceptibility as a function of frequency, whose peak position changes due to the modification of the hydrodynamic radius of bio-conjugated magnetic nanoparticles upon binding to target bio-molecules. The advantage of this approach includes its relative simplicity and integrity compared to methods that use substrate-based stray-field detectors.

Inhibition of Overexpressed CDC-25.1 Phosphatase Activity by Flavone in Caenorhabditis elegans

  • Kim, Koo-Seul;Kawasaki, Ichiro;Chong, Youhoon;Shim, Yhong-Hee
    • Molecules and Cells
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    • 제27권3호
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    • pp.345-350
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    • 2009
  • We previously reported that flavone induces embryonic lethality in Caenorhabditis elegans, which appeared to be the result of cell cycle arrest during early embryogenesis. To test this possibility, here we examined whether flavone inhibits the activity of a key cell cycle regulator, CDC-25.1 in C. elegans. A gain-of-function cdc-25.1 mutant, rr31, which exhibits extra cell divisions in intestinal cells, was used to test the inhibitory effects of flavone on CDC-25 activity. Flavone inhibited the extra cell divisions of intestinal cells in rr31, and modifications of flavone reduced the inhibitory effects. The inhibitory effects of flavone on CDC-25.1 were partly, if not completely, due to transcriptional repression.

자연치즈의 제조과정 중 숙성의 중요성 (Importance of Ripening during Natural Cheese Making)

  • 홍윤호
    • Journal of Dairy Science and Biotechnology
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    • 제31권2호
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    • pp.195-200
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    • 2013
  • The ripening of cheese allows for the development of characteristic taste and flavour, nutritional substances, bio-active components and texture, helping to improve quality. Many different microbiological, biochemical and nutritional changes occur during the process depending on the quality of raw milk, added cultures and enzymes, as well as specific processing and ripening conditions. During the ripening lactose is hydrolyzed to lactic, propionic and acetic acid, helping to reduce potential effects of the problem of lactose intolerance. Fat is hydrolyzed to butyric, propionic and conjugated linoleic acid, which function as bio-active substances. Protein is hydrolyzed to different peptides and amino acids which all show various bio-activities. However, errors of cheese ripening can happen and affect the quality of the product. To guarantee good quality cheese the process needs to be managed carefully with the right microbes used and ensuring cleanliness of processing facilities, staff, ventilation and hazard analysis and critical control points (HACCP). Research into and controlling of ripening technology is crucial for producing high quality cheeses.

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생체에너지(기) 전달에 의한 경락 반응 분석 (Analysis of meridian response by bio-energy transmission)

  • 정석준;이용흠;정동명
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2002년도 하계종합학술대회 논문집(5)
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    • pp.141-144
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    • 2002
  • Acupuncture effect principle on meridians is what physical stimulation does on general physiology so that it gets into new equilibrium from the fallen function state of human body. However, it is generally accepted that western medicine has regarded the action passageway of various kinds stimulation as nerve fluids tissue or nerve-endocrine-immune system. These regard any action for all meridians as a response to the stimulation. These are not treatments for transmission of the energy. This paper compares the change of electric potential when operator's bio-energy is passed on and when is not. As a result of it, the effect of acupuncture is different when a operator's bio-energy is passed on to meridians and it isn't. Therefore, it means that the general acupuncture is more effective than the insulation one. Moreover, we could certify that there is close relation between an operator's energy transmission and acupuncture effect.

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비침습적 복압 측정을 위한 생체 임피던스 전극의 최적 위치 선정 (Optimum electrode selection for measuring the abdominal pressure using bio-impedance method)

  • 안양수;김거식;송철규
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2007년도 심포지엄 논문집 정보 및 제어부문
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    • pp.46-48
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    • 2007
  • In this study, we determined the optimum electrode pair for measuring the abdominal pressure using bio-impedance method. Because impedance changes differ from a weight, a height, contractile force, volume of muscle and blood other or whatever of individuals, it was quantified using values of impedance change, correlation coefficient and SNR. Our results showed the optimum electrode pair (1, 9) which could detect impedance changes due to an increase of the intensity of the abdominal pressure. The correlation coefficient and quadratic function between the RMS values of EMG and the impedance changes were 0.87 and $y=0.0014x^2$+0.0620x+0.6958, respectively. It demonstrated that the abdominal pressure could be measured non-invasively and simply using bio-impedance method. We propose that this optimum electrode configuration would be useful for future studies involving the convenient measurement of abdominal pressure by ambulatory urodynamics monitoring study.

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