• Journal of Applied Biological Chemistry
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• 제49권4호
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• pp.162-164
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• 2006

The roots of Codonopsis lanceolata afforded tangshenoside I(1) and $\beta$-adenosine (2) as $\alpha$-glucosidase inhibitors. Their structures were unambiguously determined by 1D and 2D NMR data including HMQC and HMBC experiments. Compounds 1 and 2 exhibited weak $\alpha$-glucosidase inhibitory activities in vitro with $IC_{50}$ of 1.4 and 9.3 mM, respectively.

• International Journal of Advanced Culture Technology
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• 제1권1호
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• pp.1-5
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• 2013

This network system for home care realized communication by the bio-physical signal, to convey physical rhythm. Four function of displacement had point of a Vision, Somatosensory, Vestibular and CNS. Bio-physical signal was decided to design a maximum points and minimum points with 0.01unit in reference level. Bio-physical signal was checked to compound physical condition of body posture for sensory organ. There detected a measurement of Vision, Somatosensory, Vestibular, CNS and BMI. The service of network system of home can be used to support a health care system for health assistant in health care center. It will expect to manage a physical parameter for network communication.

• Journal of Microbiology and Biotechnology
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• 제16권7호
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• pp.1139-1143
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• 2006

Various techniques and strategies have been developed for the identification of intracellular metabolic conditions, and among them, isotope balance-based flux analysis with gas chromatography/mass spectrometry (GC/ MS) has recently become popular. Even though isotope balance-based flux analysis allows a more accurate estimation of intracellular fluxes, its application has been restricted to relatively small metabolic systems because of the limited number of measurable metabolites. In this paper, a strategy for incorporating isotope balance-based flux data obtained for a small network into metabolic flux analysis was examined as a feasible alternative allowing more accurate quantification of intracellular flux distribution in a large metabolic system. To impose GC/MS based data into a large metabolic network and obtain optimum flux distribution profile, data reconciliation procedure was applied. As a result, metabolic flux values of 308 intracellular reactions could be estimated from 29 GC/ MS based fluxes with higher accuracy.

• 통합자연과학논문집
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• 제7권1호
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• pp.62-66
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• 2014

This study aims to implement the emergency monitoring robot system which predicts the current state of the patients without visiting the medical institutions by measuring the basic health status of the user's blood pressure, heartbeat, and basic health status of body temperature in the disaster emergency situation based on the Smart Grid. By arranging a large number of sensor(blood pressure, heartbeat, body temperature sensor) and measuring the bio signs, so the attached wireless XBee sensor can be stored in DB of robot, and it aims to draw the current state of the patients by analysis of stored bio data. Among 300 data obtained from the sensor, 1st data to 100th data were used for learning, and from 101st data to 300th data were used for assessment. 12 results were different among the total 300 assessment data, so it shows about 96% accuracy.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권4호
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• pp.1317-1341
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• 2021

Nowadays, the Internet of Things (IoT) is adopted to enable effective and smooth communication among different networks. In some specific application, the Wireless Sensor Networks (WSN) are used in IoT to gather peculiar data without the interaction of human. The WSNs are self-organizing in nature, so it mostly prefer multi-hop data forwarding. Thus to achieve better communication, a cross-layer routing strategy is preferred. In the cross-layer routing strategy, the routing processed through three layers such as transport, data link, and physical layer. Even though effective communication achieved via a cross-layer routing strategy, energy is another constraint in WSN assisted IoT. Cluster-based communication is one of the most used strategies for effectively preserving energy in WSN routing. This paper proposes a Bio-inspired cross-layer routing (BiHCLR) protocol to achieve effective and energy preserving routing in WSN assisted IoT. Initially, the deployed sensor nodes are arranged in the form of a grid as per the grid-based routing strategy. Then to enable energy preservation in BiHCLR, the fuzzy logic approach is executed to select the Cluster Head (CH) for every cell of the grid. Then a hybrid bio-inspired algorithm is used to select the routing path. The hybrid algorithm combines moth search and Salp Swarm optimization techniques. The performance of the proposed BiHCLR is evaluated based on the Quality of Service (QoS) analysis in terms of Packet loss, error bit rate, transmission delay, lifetime of network, buffer occupancy and throughput. Then these performances are validated based on comparison with conventional routing strategies like Fuzzy-rule-based Energy Efficient Clustering and Immune-Inspired Routing (FEEC-IIR), Neuro-Fuzzy- Emperor Penguin Optimization (NF-EPO), Fuzzy Reinforcement Learning-based Data Gathering (FRLDG) and Hierarchical Energy Efficient Data gathering (HEED). Ultimately the performance of the proposed BiHCLR outperforms all other conventional techniques.

• 대한의용생체공학회:의공학회지
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• 제26권6호
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• pp.399-406
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• 2005

In these days, HIS(Hospital Information System) raise the quality of medical services by effective management of medical records. As computing environment was developed, it is possible to search information quickly. But, standard medical data exchange is not completed between medical clinic and another organ so far. In case of patient transfer, past medical record was not efficiently transmitted. It be feasible treatment delay or medical accident. It is trouble that medical records is transferred by a person and communicate with each other. Extensible Markup Language (XML) is a simple, very flexible text format derived from SGML. Originally designed to meet the challenges of large-scale electronic publishing, XML is also playing an increasingly important role in the exchange of a wide variety of data on the Web and elsewhere. Form in system of company product, relative organs that handle bio-signal data is each other dissimilar and integration and to transmit to supplement bottleneck this research uses XML. In this study, it is discussed about sharing of medical data using XML web technology to standard medical record between hospital and relative organization The data structure model was designed to manage bio-signal data and patient record. We experimented about data transmission and all-in-one between different systems (one make use of MS-SQL database system and the other manage existent bio-signal data in itself form in file in this research). In order to search and refer medical record, the web-based system was implemented. The system that can be shared medical data was tested to estimate the merits of XML. Implemented XML schema confirms data transmission between different data system and integration result.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 2017년도 춘계공동학술대회
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• pp.31-31
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• 2017

On farm evaluation for the control of airborne diseases like FMD and flu virus has been done in past but control of disease in process of transportation of livestock and manures is still needed. The objective of this study was to predict a common pattern of livestock vehicles movement. The analysis were done on GPS data, collected from drivers of livestock vehicles in Jeju Island, South Korea in year 2012 and 2013. The GPS data include the coordinates of moving vehicles according to time and dates, livestock farms and manure keeping sites. 2012 year data was added to ArcGIS and different tools were used for predicting common vehicle moving pattern. The common pattern of year 2012 were determined and considered as predicted common pattern for year 2013. To compare with actual pattern of year 2013 the same analysis was done to find the difference in 2012 and 2013 pattern. When the manure keeping sites and livestock farms were same in both years, as a result common pattern of 2012 and 2013 were similar but difference were found in patterns when the manure keeping sites and livestock farms were changed. In future for more accurate results and to predict the accurate pattern of vehicles movement, more dependent and independent variables will be required to make a suitable model for prediction.

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2003년도 제2차 연례학술대회 발표논문집
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• pp.164-169
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• 2003

In this paper, we propose the integrated Bayesian network framework to reconstruct genetic regulatory networks from genome expression data. The proposed model overcomes the dimensionality problem of multivariate analysis by building coherent sub-networks from confined gene clusters and combining these networks via intermediary points. Gene Shaving algorithm is used to cluster genes that share a common function or co-regulation. Retrieved clusters incorporate prior biological knowledge such as Gene Ontology, pathway, and protein protein interaction information for extracting other related genes. With these extended gene list, system builds genetic sub-networks using Bayesian network with MDL score and Sparse Candidate algorithm. Identifying functional modules of genes is done by not only microarray data itself but also well-proved biological knowledge. This integrated approach can improve there liability of a network in that false relations due to the lack of data can be reduced. Another advantage is the decreased computational complexity by constrained gene sets. To evaluate the proposed system, S. Cerevisiae cell cycle data [1] is applied. The result analysis presents new hypotheses about novel genetic interactions as well as typical relationships known by previous researches [2].

• 한국콘텐츠학회논문지
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• 제11권3호
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• pp.65-72
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• 2011

첨단 과학기술의 등장으로 유전자 정보의 활용 방법과 다양한 분야에서의 융합 형태가 속출하고 있는 현실에 우리는 서있다. 바이오 데이터의 분석을 기반으로 많은 연구와 개발이 이루어지면서 새로운 연관성과 정보를 찾아내기 위한 바이오인포매틱스의 많은 목표들이 설정되고 있는 실정에서 데이터의 정확한 분석을 도울 수 있는 도구의 필요성이 더욱 더 대두되고 있다. 본 논문에서는 기존에 제공되는 바이오 데이터 분석을 위한 여러 가지 도구들의 단점들을 보완할 수 있는 시스템을 개발함으로써 사용자에게 보다 편리한 연구 도구를 제공하고자 한다. 바이오 데이터 분석을 위한 작업으로 ORF 축출, 바이오 서열 정보 검색 및 유사성 비교등의 작업을 분리된 환경이 아닌 통합된 환경에서 제공하고 기존 분석 시스템에서 부족한 연속성을 제공하도록 설계하였다.

• 한국IT서비스학회지
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• 제10권1호
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• pp.177-190
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• 2011

Due to the growth of economy and the advancement of IT, the life expectancy has been prolonged and the interests in health have greatly increased. Recently the request for systems that enable measuring the bio-signals of patients in the non medical organizations, such as home, and transmitting them to medical staffs at remote sites for monitoring them. In this paper, we present an agent-based u-health system for patients or suspects with heart diseases. Our system consists of portable devices for measuring bio-signals and agents that perform data collection, data storage, automatic detection of abnormal status in patients, and HL7-based data exchange in a cooperative way. The main features of the system are : the agent-based architecture facilitates the addition of new service modules as well as the modification of existing ones; an intelligent agent is provided which automatically detects situations in which the bio-signals of patients are abnormal; the medical data standard is supported so that the communication with other systems is very easy. To our survey, there have been few previous systems which support all those features in a seamless way.