• 제목/요약/키워드: Benzyl benzoate

검색결과 19건 처리시간 0.028초

히말라야의 토양 곰팡이, Preussia sp. 배양액으로부터 추출된 화학 성분들 및 항 염증 활성 (Chemical constituents from the culture filtrate of a Himalayan soil fungus, Preussia sp. and their anti-inflammatory activity)

  • 윤의중;서승석;임정한;김일찬;한세종
    • 미생물학회지
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    • 제54권1호
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    • pp.18-23
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    • 2018
  • 히말라야산의 동토에서 발견된 Preussia sp.로부터 신규 벤조산 유도체 benzyl 2,4-di(benzyloxy)benzoate (1)와 6개의 알려진 화합물들(2-7)이 분리되었다. 신규물질 및 다른 화합물들의 구조는 1D-와 2D NMR실험 및 문헌값과의 비교에 의하여 결정되었다. 화합물 2-7은 동 속 및 Sporormiaceae과에서 처음으로 얻어졌다. 분리된 물질들은 쥐의 대식세포 RAW 264.7 cells에서 lipopolysaccharide (LPS) 처리에 의하여 유도된 nitric oxide (NO)의 생성량 억제를 측정하였다. 화합물 1번과 2번은 100 mg/ml의 농도로 처리했을 때 LPS에 의하여 유도된 NO 생성량을 각각 50.7% 및 88.5%까지 억제하는 것을 보였다.

Risk assessment of endocrine disruptors in cosmetics

  • Lee, Jeong-Pyo;Choi, Sang-Sook;Son, Kyung-Hun;Yang, Seong-Jun;Kim, Shin-Ok;Paek, Ock-Jin;Cho, Hyeon-Seo;Kim, Young-Ok
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.403.3-404
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    • 2002
  • Dimethyl phthalate(DMP). diethyl phthalate(DEP), di-n-butyl phthalate (DBP). butyl benzyl phthalate(BBP). bis(2-ethylhexyl)phthalate(DEHP) and di-n-octyl phthalate(DOP) in lotions was determined by gas chromatography. and benzyl benzoate was used as the intermal standard. The separation of the six phthalates and internal standard was optimized, and the optimal analytical conditions were as follows: column. DB-1701 (I.D. 0.25mm): mobile phase. helium: oven temperature 20$0^{\circ}C$ (10 min) ${\rightarrow}10^{\circ}C$/min ${\rightarrow}260^{\circ}C$/min(30min), injector temperature 23$0^{\circ}C$, detector temperature 28$0^{\circ}C$. (omitted)

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충남 서산군 국민학교 학생에 있어서 머릿이(Head Louse) 감염상황 (Head Louse Infestation among Primary School Children in Seosan-gun, Chungnam Province)

  • 이순형;오창완채종일
    • Parasites, Hosts and Diseases
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    • 제22권1호
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    • pp.141-143
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    • 1984
  • The head louse infestation had been no problem since 1960s in Korea. However, the present study revealed high infestation rate among the primary school children in Seosan-gun, Chungnam Province in July 1983. The cases of louse positive were determined by identifying the adult worms and/or their llits on scalp and hairs. The overall louse positive rate among 615 children examined was 73.5%. The rate was higher in girls (78.8%) than in boys (67.6%) and was highest in 3rd-4th school grades. It was observed that the more the number of family members the higher the infestation rate of children. The positive children were treated with 20% benzyl benzoate solution after the teat for louscidal effect in petri dish. However, establishment of intensive control measure is needed to prevent further infestation.

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발광유전자 재조합 균주 활성 촉진 조건이 석유계 탄화수소 오염지하수 모니터링에 미치는 영향 (Effect of Bioluminescence Stimulating Agent of the Genetically Engineered Strain KG1206 on the Monitoring of the Petroleum Hydrocarbon Contaminated Groundwater Samples)

  • 고경석;공인철
    • 대한환경공학회지
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    • 제30권1호
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    • pp.79-84
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    • 2008
  • 본 연구에서는 유전자 재조합 발광균주, Pseudomonas putida mt-2 KG1206,의 발광 촉진조건을 석유계 탄화수소 오염 지하수에 적용 가능성에 대해 조사하였다. 일반적으로 순수 유도제 오염원에 대한 발광 강도는 m-methyl benzyl alchohol > m-toluate > toluene > m-xylene > benzoate > p-xylene > o-xylene의 순으로 나타났다. 일반적으로 지하수에 오염된 유도제 오염원의 농도에 따라 발광 정도가 관찰되었다. 그러나 일부 지하수 시료의 경우에는 낮은 농도에 높은 발광과 같은 현상을 관찰할 수 있었다. 이러한 현상은 환경시료의 수질 복잡성에 따른 영향일 것이다. 선행연구에서 발광촉진제로 알려진 SL (sodium lactate)와 KNO$_3$에 의한 발광영향을 비교하였다. 모두 발광을 촉진하였지만, KNO$_3$가 조금 더 촉진력이 강한 것으로 조사되었다. 질소화합물(20 g KNO$_3$/L) 첨가군 시료의 발광균주는 첨가하지 않은 대조군에 비해 뚜렷하게 발광이 높게 나타났다. 따라서 일반적으로 낮은 유도제 오염원 함유 시료에 대해서는 발광촉진 조건이 지하수 오염원 검출 및 모니터링을 용이하게 할 수 있을 것이다. 또한 비슷한 특성을 가진 다양한 발광균주를 더욱 효율적으로 오염지역의 기초평가에 이용할 수 있는 조건이 될 수 있을 것이다.

코발트 카르보닐 촉매에 의한 브로모벤질 브로미드의 카르보닐화 (II). 알킬(알콕시메틸)벤조에이트의 선택성 합성 (Carbonylation of Bromobenzyl Bromide Catalyzed by $Co_2(CO)_8(II)$. Selective Synthesis of Alkyl(alkoxymethyl)benzoate)

  • 심상철;도칠훈;윤영주;조찬식;우병원;오대희
    • 대한화학회지
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    • 제35권1호
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    • pp.90-95
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    • 1991
  • 할로벤질 할라이드의 선택적 카르보닐화에 대한 방법을 검토하였다. 알킬(알콕시메틸)벤조에이트는 한 반응기에서 두 반응에 의해 완성되며, 일차로 알코올 용매하에서 알콕시 음이온을 할로벤질 할라이드와 반응시키면, 알킬 할로벤질 에테르가 Williamson ether 합성법에 의해 얻어진다. 이차로 Na$_2$CO$_3$, CH$_3$I 및 Co$_2$(CO)$_8$을 첨가하고, 일산화탄소 기류하에서 반응시키면, 알릴할라이드 부분이 카르보닐화되어 알킬(알콕시메틸)벤조에이트를 높은 수득률로 얻을 수 있었다.

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Acaricidal Components of Medicinal Plant Oils Against Dermatophagoides farinae and Dermatophagoides pteronyssinus

  • Cho, Jang-Hee;Sung, Bo-Kyung;Lim, Mi-Youn;Kim, Hyeon-Jin;Lee, Sang-Guei;Lee, Hoi-Seon
    • Journal of Microbiology and Biotechnology
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    • 제14권3호
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    • pp.631-634
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    • 2004
  • The oils of Acorus gramineus, Cinnamomum sieboldii, Eugenia aromatica, and Inula helenium were tested for their acaricidal activity against Dermatophagoides farinae and D. pteronyssinus. Responses varied according to dose and mite species. As compared to the oils, the oil most toxic to D. farinae and D. pteronyssinus was E. aromatica, followed by C. sieboldii, A. gramineus, and I. helenium. On the basis of $LD_{50}$ values of the oils in A. gramineus, C. sieboldii, and E. aromatica, the compound most toxic against D. farinae and D. pteronyssinus was eugenol congeners (isoeugenol>eugenol>acetyleugenol) followed by benzyl benzoate, salicylaldehyde, safro1, DEET, cinnamyl alcohol, and 3-carene. As a naturally occurring acaricide, these oils and eugenol congeners could be useful as new acaricidal agents against Dermatophagoides spp.

Prostaglandin $F_{2\alpha}$ 처리에 따른 과배란 가토의 난관내 난자운반 및 분포에 관한 연구 (The Study of Egg Transports and distribution Patterns in the Oviducts of Superovulated Rabbits by Administrations of $PGF_{2\alpha}$)

  • 변태호;심금섭;이재근
    • 한국가축번식학회지
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    • 제8권1호
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    • pp.10-15
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    • 1984
  • This experiment was carried out to study the egg transports and distribution patterns in the oviducts of superovulated rabbits by administrations of PGF2$\alpha$. Group I (3 does) and Group II (3 does) were killed at 24 hours, 48 hours after mating, respectively. Group III (6 does0 received a single injection of 5mg/Kg of body weight of PGF2$\alpha$ at 24 hours after mating and killed at 4 hours after PGF2$\alpha$ administration. The oviducts were frozen in LN-gas, thawed using Howe's method, and cleared in Benzyl-Benzoate sol. using Orsini's technique. The location of the eggs and the AIJ. were identified using transmitted light from a dissecting microscope. The results obtained were as follows: 1. The average numbers of detected eggs from the oviduct were 28.6 (26-32), 26.0 (24-29), and 27.1 (22-34) in Group I, II, and III, respectively. 2. Detection rate was 88.7%, 76.4%, and 84.9% in Group I, II, and III, respectively. 3. The positionof all AIJ. was 44.2% to 55.0%(av. 49.5%) of the distance from the fimbriae to the UTJ.(Utero-Tubal Junction). 4. The changes of egg distribution patterns were as follows: Group I Ampulla : 52.3%, Isthmus : 47.7%, Group II Ampulla : 8.9%, Isthmus : 91.1% Group III Ampulla : 8.0% Isthmus : 92.0%.

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참쑥(Artemisia Lavandulaefolia DC)의 방향성분 (Flavor Components of Artemisia Lavandulaefolia DC)

  • 최경숙;최봉영;박형국;김정한;박종세;윤창노
    • 한국식품과학회지
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    • 제20권6호
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    • pp.774-779
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    • 1988
  • 참쑥(Artemisia lavandulaefolia DC)의 정유를 gas chromatogaphy/mass spectrometry(GC/MS)로 정성분석하고, 저장조건을 달리하여 정유성분의 변화를 살펴본 결과, 다음과 같은 결론을 얻었다. 1. 186 이상의 화합물이 검출되었으며, 그 중 1,8-cineol, camphor, ${\beta}-thujone$, caryophyllene, borneol, coumarin, linalool, terpineol, sabinene, 7-methoxy coumarin ${\alpha}-copaene$, humulene과phytol이 중요성분이었다. Artemisia species에서는 지금까지 밝혀진 바 없는 3,6,6-trimethyl norpinanol, ${\beta}-farnesene$, 7-methoxy coumarin, ${\alpha}-curcumene$ 등이 검출되었다. 2. 참쑥의 저장에 따른 색과 변화를 조사한 결과, 온도에 의해 갈색화와 성분의 증감이 있었다. 즉, 냉암소에 보관된 시료는 변화가 거의 없었으나, 상온방치한 시료는 Air와 질소에 상관없이 모두 변화가 있었다. 1,8-cineol, limonene, 2,2,4-trimethyl 1,3-dioxolane-4-ethanol, terpinene-4-ol 등은 감소하였으며, ${\beta}-phellandrene$, benzyl benzoate, broneol, ${\alpha}-terpineol$, humulene 등은 증가하였다.

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Evaluation of Herbicidal Potential of Essential Oils and their Components under In vitro and Greenhouse Experiments

  • Choi, Hae-Jin;Sowndhararajan, Kandhasamy;Cho, Nam-Gyu;Hwang, Ki-Hwan;Koo, Suk-Jin;Kim, Songmun
    • Weed & Turfgrass Science
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    • 제4권4호
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    • pp.321-329
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    • 2015
  • The present study aimed to evaluate the phytotoxic potential of essential oils. For this purpose, 18 essential oil samples extracted from Korean plants and 64 commercial essential oils were screened for their phytotoxic potential against the seedling growth of Brassica napus L. (rapeseed). Among the 82 samples, 11 commercial oils (cinnamon, citronella, clove, cumin seed, geranium, jasmine, lemongrass, palmarosa, pimento, rose otto and spearmint) strongly inhibited the seedling growth with $GR_{50}$ value < $150{\mu}g\;mL^{-1}$. Major components from these effective essential oils were identified by solid phase microextraction/gas chromatography-mass spectrometry (SPME/GC-MS). GC-MS analyses revealed that the effective samples mainly consist of benzyl benzoate, carvone, citral, citronellol, eugenol, geraniol, D-limonene and terpinene. Subsequently, bioactivity of these individual components was evaluated against the seedling growth of B. napus, Echinochloa crus-galli and Aeschynomene indica. The components from different chemical groups exhibited different potency in inhibiting the seedling growth with varied $GR_{50}$ values ranged from $29{\mu}g\;mL^{-1}$ to > $1000{\mu}g\;mL^{-1}$. In the greenhouse experiment, citral and geraniol completely suppressed the growth of all the tested 10 plants at $100kg\;ha^{-1}$. In conclusion, the individual essential oil components geraniol and citral could be used as natural herbicides for weed management.