Risk assessment of endocrine disruptors in cosmetics

  • Lee, Jeong-Pyo (Korea Food and Drug Administration, Department of Drug Evaluation) ;
  • Choi, Sang-Sook (Korea Food and Drug Administration, Department of Drug Evaluatio) ;
  • Son, Kyung-Hun (Korea Food and Drug Administration, Department of Drug Evaluatio) ;
  • Yang, Seong-Jun (Korea Food and Drug Administration, Department of Drug Evaluatio) ;
  • Kim, Shin-Ok (Korea Food and Drug Administration, Department of Drug Evaluatio) ;
  • Paek, Ock-Jin (Korea Food and Drug Administration, Department of Drug Evaluatio) ;
  • Cho, Hyeon-Seo (Korea Food and Drug Administration, Department of Drug Evaluatio) ;
  • Kim, Young-Ok (Korea Food and Drug Administration, Department of Drug Evaluation)
  • Published : 2002.10.01

Abstract

Dimethyl phthalate(DMP). diethyl phthalate(DEP), di-n-butyl phthalate (DBP). butyl benzyl phthalate(BBP). bis(2-ethylhexyl)phthalate(DEHP) and di-n-octyl phthalate(DOP) in lotions was determined by gas chromatography. and benzyl benzoate was used as the intermal standard. The separation of the six phthalates and internal standard was optimized, and the optimal analytical conditions were as follows: column. DB-1701 (I.D. 0.25mm): mobile phase. helium: oven temperature 20$0^{\circ}C$ (10 min) ${\rightarrow}10^{\circ}C$/min ${\rightarrow}260^{\circ}C$/min(30min), injector temperature 23$0^{\circ}C$, detector temperature 28$0^{\circ}C$. (omitted)

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