• Journal of the Korean Data and Information Science Society
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• v.25 no.6
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• pp.1407-1418
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• 2014

Korean youth spend tremendous time in school for preparing for college admissions. Their academic achievement and overall satisfaction with their lives are affected by how well they adapt to life in school. Successful adaptation to school is important enough to affect a student's future social life. One of the factors that affect adaptation to school is the psychological condition of adolescent anxiety. Anxiety is one of the common mental disorders that appear in people who are not familiar with new environments. Anxiety is known to be related to behavioral problems, and problems with psychological and emotional adaptation. This condition is dramatically increased in adolescents.Parental conflict in particular is known to be a major factor in affecting youth anxiety. As parental conflict became more severe, children felt more negative emotions such as anger, sadness and worry. Moreover, when a child's issue caused the parental conflict, there were more side effects in the emotional condition of the child. This study shows how parental conflict affects a child's anxiety and a child's school life.This problem is analyzed through structural equation modeling.

• The KIPS Transactions:PartA
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• v.12A no.6 s.96
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• pp.523-530
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• 2005

When a PCI 2.2 bus master requests data using Memory Read command, a target device may hold PCI bus without data to be transferred for long time because a target device needs time to prepare data infernally. Because the usage efficiency of the PCI bus and the data transfer efficiency are decreased due to this situation, the PCI specification recommends to use the Delayed Transaction mechanism to improve the system performance. But the mechanism cann't fully improve performance because a target device doesn't know the exact size of prefetched data. In the previous work, we propose a new method called Prefetch Request when a bus master intends to read data from the target device. In this paper, we design PCI 2.2 controller and local device that support the proposed method. The designed PCI 2.2 controller has simple local interface and it is used to convert the PCI protocol into the local protocol. So the typical users, who don't know the PCI protocol, can easily design the PCI target device using the proposed PCI controller. We propose the basic behavioral verification, hardware design verification, and random test verification to verify the designed hardware. We also build the test bench and define assembler instructions. And we propose random testing environment, which consist of reference model, random generator ,and compare engine, to efficiently verify corner case. This verification environment is excellent to find error which is not detected by general test vector. Also, the simulation under the proposed test environment shows that the proposed method has the higher data transfer efficiency than the Delayed Transaction about $9\%$.

• The Korean Journal of Physiology and Pharmacology
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• v.16 no.6
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• pp.405-411
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• 2012

The spontaneous axon regeneration of damaged neurons is limited after spinal cord injury (SCI). Recently, mesenchymal stem cell (MSC) transplantation was proposed as a potential approach for enhancing nerve regeneration that avoids the ethical issues associated with embryonic stem cell transplantation. As SCI is a complex pathological entity, the treatment of SCI requires a multipronged approach. The purpose of the present study was to investigate the functional recovery and therapeutic potential of human MSCs (hMSCs) and polymer in a spinal cord hemisection injury model. Rats were subjected to hemisection injuries and then divided into three groups. Two groups of rats underwent partial thoracic hemisection injury followed by implantation of either polymer only or polymer with hMSCs. Another hemisection-only group was used as a control. Behavioral, electrophysiological and immunohistochemical studies were performed on all rats. The functional recovery was significantly improved in the polymer with hMSC-transplanted group as compared with control at five weeks after transplantation. The results of electrophysiologic study demonstrated that the latency of somatosensory-evoked potentials (SSEPs) in the polymer with hMSC-transplanted group was significantly shorter than in the hemisection-only control group. In the results of immunohistochemical study, ${\beta}$-gal-positive cells were observed in the injured and adjacent sites after hMSC transplantation. Surviving hMSCs differentiated into various cell types such as neurons, astrocytes and oligodendrocytes. These data suggest that hMSC transplantation with polymer may play an important role in functional recovery and axonal regeneration after SCI, and may be a potential therapeutic strategy for SCI.

• Nutrition Research and Practice
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• v.12 no.3
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• pp.191-198
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• 2018

BACKGROUD/OBJECTIVES: Neuroinflammation plays critical role in neurodegenerative disorders, such as Alzheimer's disease (AD). We investigated the effect of three licorice varieties, Glycyrhiza uralensis, G. glabra, and Shinwongam (SW) on a mouse model of inflammation-induced memory and cognitive deficit. MATERIALS/METHODS: C57BL/6 mice were injected with lipopolysaccharide (LPS; 2.5 mg/kg, intraperitoneally) and orally administrated G. uralensis, G. glabra, and SW extract (150 mg/kg/day). SW, a new species of licorice in Korea, was combined with G. uralensis and G. glabra. Behavioral tests, including the T-maze, novel object recognition and Morris water maze, were carried out to assess learning and memory. In addition, the expressions of inflammation-related proteins in brain tissue were measured by western blotting. RESULTS: There was a significant decrease in spatial and objective recognition memory in LPS-induced cognitive impairment group, as measured by the T-maze and novel object recognition test; however, the administration of licorice ameliorated these deficits. In addition, licorice-treated groups exhibited improved learning and memory ability in the Morris water maze. Furthermore, LPS-injected mice had up-regulated pro-inflammatory proteins, such as inducible nitric oxide synthase (iNOS), cyclooxygenase-2, interleukin-6, via activation of toll like receptor 4 (TLR4) and nuclear factor-kappa B ($NF{\kappa}B$) pathways in the brain. However, these were attenuated by following administration of the three licorice varieties. Interestingly, the SW-administered group showed greater inhibition of iNOS and TLR4 when compared with the other licorice varieties. Furthermore, there was a significant increase in the expression of brain-derived neurotrophic factor (BDNF) in the brain of LPS-induced cognitively impaired mice that were administered licorice, with the greatest effect following SW treatment. CONCLUSIONS: The three licorice varieties ameliorated the inflammation-induced cognitive dysfunction by down-regulating inflammatory proteins and up-regulating BDNF. These results suggest that licorice, in particular SW, could be potential therapeutic agents against cognitive impairment.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.2
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• pp.300-305
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• 2011

The present study was investigated the neuroprotective effects of acupuncture at ST36 on learning and memory deficits after transient cerebral ischemia in a gerbil model. The animals were randomly divided into three groups (n=7 in each group): the sham operation group (SHAM), ischemia-induced and ST36 acupuncture group (ISC + ST36), and the ischemia-induced and Tail-acupuncture group (ISC + TAIL). For the acupuncture stimulation, stainless steel needles, 0.3 mm in diameter, were inserted bilaterally into the ST36 locus or the tail and stimulated for 1 min/day for 14 days. Using the Morris water maze test, the animals were tested on spatial learning and memory. In addition, the effects of acupuncture on memory storage and the choline acetyltransferase (ChAT) activity, in the hippocampal CA1 area, were investigated by ChAT immunohistochemistry. Transient cerebral ischemia produced impaired performance on the MWM test (DAY 5: p<0.01 and retention test: p<0.05) and severely decreased ChAT immunoreactivity in the CA1 hippocampal area compared to the SHAM group (p<0.05). However, improved learning and memory were observed (DAY 5: p<0.05 and retention test: p<0.01) as well as a significantly reduced loss of ChAT immunoactivity in the hippocampal CA1 region (p<0.001) after acupuncture stimulation at ST36 were observed. These results show that acupuncture at ST36 ameliorated the learning and memory deficits at least in part through the cholinergic system. The findings of this study provide potential data that acupuncture is useful for the treatment of some of the behavioral impairs of transient cerebral ischemia.

• Health Policy and Management
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• v.25 no.3
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• pp.162-173
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• 2015

Background: The aim of the current study was to investigate the factors related to the non-practice of cancer screening in cancer survivors, who are at high risk of developing second cancers. Methods: This study is a cross-sectional analysis of 1,125 cancer survivors ${\geq}19$ years old who participated in the Korean National Health and Nutrition Examination Surveys IV and V (2007-2012). A Rao-scott chi-square test and a survey logistic regression analysis were employed respectively to analyze the difference of cancer survivors in cancer screening by each characteristic and the factors related to the non-practice of cancer screening in cancer survivors. Results: Among total subjects, 33.5% did not participate in cancer screening in the last two years. Results from a fully adjusted logistic model showed that the non-practice of cancer screening in cancer survivors was significantly associated with variables such as sex, age, marital status, education level, monthly income, and drinking a alcoholic beverage Specifically, the odds ratio of non-practice of cancer screening was higher in males than in females, in the younger group than in older group, in the group with no spouse than in the group with a spouse; in a group with a low level of education than in a group with a high level of education; in a group with the lowest income level than in a group with the other levels of income; or in non-drinkers than in drinkers. Conclusion: Health policies to reduce the non-practice rate of cancer screening in cancer survivors should be designed and implemented with close attention to cancer survivors' socio-economic characteristics such as sex, age, marital status, education, and income, along with a health behavioral characteristic as drinking.

• Journal of Food Hygiene and Safety
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• v.33 no.2
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• pp.89-93
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• 2018

High sodium dietary habits may cause various diseases, thereby threatening the public health. Various efforts have been made to control high sodium use in diets, but few studies have been conducted on health communication efforts to modify such habits. This study looks for suggestions for diet improvement education by examining whether or not high sodium dietary habits can be predicted by a consumer's perception on the threat and controllability of high sodium diets. In this study, a questionnaire was developed to measure the severity, vulnerability, efficiency, efficacy, and behavioral tendencies of the consumer, which were subscales of the protective motivation theory. The questionnaire was given to university students and their families in Chungnam Province. The results of a statistical analysis were as follows: First, more young people preferred high-sodium diets than older people. Second, the correlation analysis showed that older people knew that they were vulnerable to the negative effects of high sodium diets, but they would not change their dietary habits until they were confident that they could control the high-sodium diet. Third, the structural model analysis showed that the higher the coping perception was, the lower was the tendency to consume a high-sodium diet. These results suggest that in the effort to reduce high-sodium diets, it is more effective to provide viable information and improve efficacy.

• Journal of the Korean Institute of Intelligent Systems
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• v.20 no.4
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• pp.503-508
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• 2010

Recently, the advance of mobile devices has made various services possible beyond simple communication. One of services is the predicting the future path of users and providing the most suitable location based service based on the prediction results. Almost of these prediction methods are based on previous path data. Thus, calculating similarities between current location information and the previous trajectories for path prediction is an important operation. The collected trajectory data have a huge amount of location information generally. These information needs the high computational cost for calculating similarities. For reducing computational cost, the meaningful location based trajectory model approaches are proposed. However, most of the previous researches are considering only the physical information such as stay time and the distance for extracting the meaningful locations. Thus, they will probably ignore the characteristics of users for meaningful location extraction. In this paper, we suggest a meaningful location extracting and trajectory simplification approach considering the stay time, distance, and additionally interaction information of user. The method collects the location information using GPS device and interaction information between the user and the others. Using these data, the proposed method defines the proximity of the people who are related with the user. The system extracts the meaningful locations based on the calculated proximities, stay time and distance. Using the selected meaningful locations the trajectories are simplified. For verifying the usability of the proposed method, we collect the behavioral data of smart phone users. Using these data, we measure the suitability of meaningful location extraction method, and the accuracy of prediction approach based on simplified trajectories. Following these result, we confirmed the usability of proposed method.

• Journal of the Korea Convergence Society
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• v.12 no.9
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• pp.113-120
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• 2021

As a result, the interaction between personal motivation and class type is not significant. On the other hand, the interaction between social motivation and class type is significant and overall online class increases engagement with educational issues. In particular, the group with low social motivation showed greater change than the group with high social motivation, so online education seems to be more effective in the group with low social motivation. It means that by stimulating students' social motivation rather than personal motivation, the effectiveness of online education can be enhanced, and it can lead to education outcomes - behavioral changes and attitudes of learners. In order to revitalize social motivation in the intensely personal space of online, it is necessary to activate social communication methods such as SNS, and development of interpersonal issues and learning materials would be more efficient. In order to derive more specific results, it is necessary to measure the level of prior knowledge and involvement of the participants in class, and to comprehensively investigate and analyze the state of learners before and after class through more variables. Finally, in order to increase the reliability of the research results, it is necessary to clearly prove it through the establishment of a structural model.

• Journal of Korean Home Economics Education Association
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• v.33 no.1
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• pp.151-167
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• 2021

This study reports on the development of a dietary education program for Korean young adults in single-person households. The 7th National Health and Nutrition Survey (2016-2018) was used to compare and analyze the dietary behavior of single-person households and multi-person households, and an online survey was conducted on 350 young adults (age 19-39 years) living in Seoul. According to the analysis, single-person households had higher rates of breakfast and eating out than multi-person households, and significantly lower average intake of energy and nutrients (p<0.05). In particular, in the case of single-person households, the lower the frequency of cooking at home, the higher the rate of breakfast and the higher the frequency of eating out and delivery food (p<0.05). Based on the survey, a dietary education program for young adults single-person households was developed by applying the DESIGN six-step procedure and social cognitive theory as a conceptual model. The first session consisted of the health and economic benefits of home-cooked meals, the second session of the importance of the breakfast and the effect of exercise in life, the third session of the importance of balanced nutrition and the principles of a healthy diet, the fourth session of food safety and storage, and the fifth session of social dining. Each session was composed of a combination of theoretical lectures to motivate 'more making and eating healthy home-cooked meals' and cooking practice for improving behavioral performance.