• Informatization Policy
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• v.26 no.2
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• pp.81-95
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• 2019

This study explores how the advanced data analysis capabilities of intelligent information technology are being utilized in politics. In particular, we focus on the fact that voter behavioral targeting in election campaigns comes into conflict with the democratic process in various ways. For this purpose, this study examines political micro-targeting and political bots. It is aimed at showing that these technology-based campaign techniques work as a factor preventing free expression of opinions and discussions, which are the core of democracy itself. Then we identify the attributes of the algorithm that affects them. As a result, this study suggests that the following issues might arise regarding intelligent information technology-based politics and democracy. First, inequality in political participation becomes more severe. Second, the public debate between voters gets more difficult. Third, superficial politics is prevalent. Fourth, single-issue politics and the exclusion of political representation is likely to increase. Fifth, political privacy might also be invaded. Based on our discussions, this study concludes that it is our role to find ways by which intelligent information technology and democracy can coexist.

• Herbal Formula Science
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• v.27 no.2
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• pp.121-136
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• 2019

Objective : To investigate the effect of sihogayonggolmoryeotang (SY) on Single Prolonged Stress(SPS)-induced Post Traumatic Stress Disorder(PTSD). Method : To confirm the effects of SY on SPS-induced PTSD, Changes in body weight, sucrose intake open field test(OFT) and forced swimming test(FST)were observed. After behavioral tests, the plasma corticosterone(CORT) from the abdominal aorta, serotonin(5-HT) from prefrontal cortex, hippocampus, amygdala and striatum, norepinephrine(NE) and dopamine(DA) from hippocampus was measured by ELISA. mRNA expression of brain-derived neurotrophic factor(BDNF) and cAMP response element-binding protein(CREB) in hippocampus was measured by RT-PCR. Result : Weight change and sucrose intakes of rats in 14th day after the administration of SY were significantly increased in the SPS + SY450 group compared to the SPS group (p<0.05). Numbers of crossing in the central zone in the OFT were significantly increased in the SPS + SY450 group (p<0.05) compared with the SPS group. The immobility time of FST was significantly decreased in SPS + SY450 group compared with SPS group (p<0.05). The change of plasma CORT concentration was significantly decreased in SPS + SY450 group compared with that in SPS group (p<0.05). The change of 5-HT concentration was significantly increased in the SPS + SY450 group at hippocampus and amygdala compared with the SPS group (p<0.05). The concentration of DA was significantly increased in the SPS + SY450 group compared with the SPS group (p<0.05). The expression of BDNF and CREB were significantly increased in SPS + SY450 group compared with the SPS group (p<0.05). Conclusion : SY administration lowered the increase of CORT caused by PTSD and increases the 5-HT concentration and reversed the decreased expression of NE and DA and BDNF and CREB by PTSD. It is postulated that SY is effective in treating PTSD by restoring cognitive function, memory impairment, unstable emotional disturbances.

• Journal of the Korea Convergence Society
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• v.10 no.8
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• pp.75-82
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• 2019

Many people suffers from multiple chronic diseases, leading cause of death and disability in the world. The purpose of this study was to investigate factors affecting multiple chronic diseases, hypertension, and diabetes. We analyzed the data of one metropolitan city of community health survey, 2015. 4,590 citizens were enrolled in this study. Prevalence of multiple chronic diseases, hypertension, and diabetes were 5.14%, 16.8%, and 3.89%, respectively. Educational attainment, income, salt intake, and BMI were identified as independent risk factors associated with multiple chronic diseases. Educational attainment, income, salt intake were significantly associated with hypertension and age, educational attainment, frequency of alcohol drinking, salt intake were associated with diabetes. Multiple chronic diseases, hypertension, and diabetes were associated with sociodemographic, economic, and health behavioral factors. We should consider these variables in the prevention and management programs and policies for patients with multiple chronic diseases.

• Journal of Korean Academy of Nursing
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• v.49 no.3
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• pp.317-328
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• 2019

Purpose: The purpose of this study was to identify the effect of ghrelin on memory impairment in a rat model of vascular dementia induced by chronic cerebral hypoperfusion. Methods: Randomized controlled groups and the posttest design were used. We established the representative animal model of vascular dementia caused by bilateral common carotid artery occlusion and administered $80{\mu}g/kg$ ghrelin intraperitoneally for 4 weeks. First, behavioral studies were performed to evaluate spatial memory. Second, we used molecular biology techniques to determine whether ghrelin ameliorates the damage to the structure and function of the white matter and hippocampus, which are crucial to learning and memory. Results: Ghrelin improved the spatial memory impairment in the Y-maze and Morris water maze test. In the white matter, demyelination and atrophy of the corpus callosum were significantly decreased in the ghrelin-treated group. In the hippocampus, ghrelin increased the length of hippocampal microvessels and reduced the microvessels pathology. Further, we confirmed angiogenesis enhancement through the fact that ghrelin treatment increased vascular endothelial growth factor (VEGF)-related protein levels, which are the most powerful mediators of angiogenesis in the hippocampus. Conclusion: We found that ghrelin affected the damaged myelin sheaths and microvessels by increasing angiogenesis, which then led to neuroprotection and improved memory function. We suggest that further studies continue to accumulate evidence of the effect of ghrelin. Further, we believe that the development of therapeutic interventions that increase ghrelin may contribute to memory improvement in patients with vascular dementia.

• Journal of the Korea Convergence Society
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• v.10 no.4
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• pp.219-227
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• 2019

The purpose of this study was to analyze relations among the stages of exercise change, exercise self-schema, and temptation of quitting exercise to figure out changes to the exercise behavior according to a psychological process. For this purpose, the study used total 297 questionnaires from adults using a public sports center. Collected data was treated with the SPSS 18.0 program, being put to the test through exploratory factor analysis, MANOVA, multiple regression analysis, and discriminant analysis. The findings were as follows: first, there were differences in exercise self-schema according to the stages of exercise change; second, there were differences in the temptation of quitting exercise between coaches and burnout according to the stages of exercise change; third, behavioral self-schema and burnout were major factors to distinguish the stages of exercise change; and finally, exercise self-schema had negative effects on burnout, and cognitive-emotional self-schema had negative effects on affect.

• Molecules and Cells
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• v.42 no.4
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• pp.301-312
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• 2019

Post-transcriptional regulation underlies the circadian control of gene expression and animal behaviors. However, the role of mRNA surveillance via the nonsense-mediated mRNA decay (NMD) pathway in circadian rhythms remains elusive. Here, we report that Drosophila NMD pathway acts in a subset of circadian pacemaker neurons to maintain robust 24 h rhythms of free-running locomotor activity. RNA interference-mediated depletion of key NMD factors in timeless-expressing clock cells decreased the amplitude of circadian locomotor behaviors. Transgenic manipulation of the NMD pathway in clock neurons expressing a neuropeptide PIGMENT-DISPERSING FACTOR (PDF) was sufficient to dampen or lengthen free-running locomotor rhythms. Confocal imaging of a transgenic NMD reporter revealed that arrhythmic Clock mutants exhibited stronger NMD activity in PDF-expressing neurons than wild-type. We further found that hypomorphic mutations in Suppressor with morphogenetic effect on genitalia 5 (Smg5) or Smg6 impaired circadian behaviors. These NMD mutants normally developed PDF-expressing clock neurons and displayed daily oscillations in the transcript levels of core clock genes. By contrast, the loss of Smg5 or Smg6 function affected the relative transcript levels of cAMP response element-binding protein B (CrebB) in an isoform-specific manner. Moreover, the overexpression of a transcriptional repressor form of CrebB rescued free-running locomotor rhythms in Smg5-depleted flies. These data demonstrate that CrebB is a rate-limiting substrate of the genetic NMD pathway important for the behavioral output of circadian clocks in Drosophila.

• Journal of Convergence for Information Technology
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• v.9 no.4
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• pp.48-58
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• 2019

Recently, companies that have already the brand familiarity based on IT technology are changing the way of financial transactions by providing mobile simple payment service. It is difficult to apply the results of research conducted on traditional financial products, although the familiarity of the brand positively affects the brand attitude and intention of use in the preceding studies. To confirm this, this study verified whether mobile simple payment services of a company with high brand familiarity can copy the service easily and have intention of use through advertisement acceptance. The empirical results showed that the advertising of brand with high familiarity could be a motivation factor to imitate new services more easily. This results is meaningful in that it confirms the importance of strategic advertising because the more higher the brand's familiarity is, the more efficient the advertising can be used in the mobile simple payment service.

• Korean journal of health promotion
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• v.18 no.4
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• pp.169-176
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• 2018

Background: The purpose of this study was to analyze the correlation between risk perception and attitudes and preventive behaviors among college students with poor health and safety consciousness. Methods: A survey was conducted in students at three universities in the metropolitan area from May 11 to 18, 2018. Four kinds of instruments were used for this study, questionnaires about attitudes, perception, prevention education and preventive behaviors. Results: The safety-related attitude depended on age: those aged <21 years had the best attitude. Education experience significantly affected perception. Preventive behaviors were more strongly and positively correlated with attitudes than with perception. The factor most significantly affecting preventive behaviors were attitudes to preventive health. Conclusions: To allow the students to change their awareness and behaviors related to sickness and accidents, first it is necessary to give education on a continuous basis so that they can obtain perception to cope with sickness and accidents; second, it is necessary to develop behavioral guidelines related to accidents in each area so that they can practice and make it a habit through attitudinal changes.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.1
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• pp.457-470
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• 2021

The banking system provides a number of important functions for the economy and is also the lifeblood and financier of the economy in each country. Large amounts of idle money have not been exploited by banks; however, banks still depend on loans, including loans from foreign banks, to meet the growing demand, as such, for banks, the cost of capital is high, the stability and business efficiency are low and banks have not promoted their internal resources to grow steadily. To achieve the goal, this research analyzes the factors affecting the choice of bank for the deposit decisions of customers in Vietnam. The study used a sample data of 250 individuals and SPSS software was used to analyze the data. The results showed that customer policy has a positive effect on customers' deposit decisions in a bank, and this is new evidence regarding behavioral theory in the case of Vietnam. Results further demonstrated that other factors such as employee image, brand, interest rate, relative influencing, and transaction time positively impact the choice of bank for the deposit decisions of customers. However, the bank's promotion strategies had no impact on the choice of bank for the deposit decisions of customers. Besides, employee image is the most influential factor in the deposit decisions, followed by the bank's brand and interest rate.

• 한국노년학
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• v.28 no.4
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• pp.1129-1145
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• 2008

In order to develop practical implications for depression among the elderly, this study examines socioeconomic and health-behavioral risk factors of geriatric depression diagnosis. Sample consists of 964 elders aged 65 and over, living in an urban community. Using the Short-form Geriatric Depression Scale(SGDS), study subjects were screened for geriatric depression to those who presented 10 points and over in SGDS. Descriptive statistics shows that about 22.2% elders are estimated to suffer from geriatric depression. Predictors of geriatric depression diagnosis were examined through logistic regression. Results show that elders who live with family, who have medical insurance, who have higher education, who don't smoke, and who do more physical activities were less likely to suffer from geriatric depression. These findings indicate that socioeconomic position such as health insurance, education and health behaviors such as smoking, physical activities are closely related to geriatric depression, suggesting that interventions on socioeconomic position and health behaviors may be effective to reduce depression among the elderly.