• Title/Summary/Keyword: Behavior indicator

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Analysis of Proliferative Potentials in Meningiomas by Ki-67, Proliferating Cell Nuclear Antigen, and Flow Cytometry (Ki-67, Proliferating Cell Nuclear Antigen, Flow Cytometry를 이용한 수막종의 증식력 분석)

  • Ahn, Jae Sung;Kim, Jeong Hoon;Kwun, Byung Duk
    • Journal of Korean Neurosurgical Society
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    • v.30 no.7
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    • pp.861-869
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    • 2001
  • Objective : In this study, we investigated the relationship between the histologic grading of meningiomas and proliferative potentials determined by the Ki-67, proliferating cell nuclear antigen(PCNA) and flow cytometry (FCM) with the aim of determining whether these potentials can be used as a parameter to the proliferative activity, in particular of atypical and malignant meningiomas. Methods : This study consisted of 47 meningiomas(6 malignant, 14 atypical, and random sampled 27 benign meningiomas). By immunohistochemical staining of Ki-67 and PCNA on formalin-fixed, paraffin-embedded sections, the anti-human rabbit polyclonal antibody against Ki-67 antigen and anti-PCNA monoclonal antibody(PC10) scores were counted. FCM was also performed on paraffin-embedded tissue using a selective staining technique for DNA. DNA ploidy, S-phase fraction, and proliferative index(PI)) were determined. Results : The results are summarized as follows ; 1) Proliferation rates as assessed by Ki-67 and PCNA closely correlated with the degree of anaplastic histologic features. 2) Proliferative potentials determined by FCM(S-phase fraction and PI) were not able to distinguish between benign and atypical/malignant meningiomas. 3) DNA ploidy was not a useful indicator of histologic grade in these tumors. 4) Proliferative potentials such as Ki-67 staining index(SI) and PCNA SI did not correlate with the ploidy pattern. 5) There was a linear correlation between Ki-67 SI and PCNA SI, but we could not find a correlation between Ki-67 SI and S-phase fraction or PI. Our results also did not show a statistically signficant correlation between PCNA SI and S-phse fraction or PI. Conclusions : We conclude that evaluation of the proliferative potentials with Ki-67 and PCNA is important as an additional factor for the prediction of malignancy in meningiomas. A dual study of Ki-67 and PCNA SIs on the same tissue might improve the accuracy with which the proliferative potential of a tumor can be predicted. We demonstrated that FCM in meningiomas is not valuable in predicting the behavior of these neoplasms, but we did observe a trend toward more malignancy with higher percent S-phase fraction and higher PI. Analysis of the S-phase fraction and PI might therefore be a useful tool to discriminate among histologic grades of meningiomas.

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A Basic Study on the Development of Indicators for Measuring the Value of Ocean Education (해양교육의 가치 측정 지표 개발에 관한 기초연구)

  • Lee, Seulgi;Kim, Tae-goun
    • Journal of Navigation and Port Research
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    • v.45 no.4
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    • pp.224-230
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    • 2021
  • It has been 16 years since the government announced its first Ocean Education Policy in 2005. Although the public consensus on the importance of ocean education has been formed, it is impossible to objectively analyze the impact of the policy on the society or the economy. The aim of this paper was to identify differences in perceptions and behaviors about the ocean between groups participating in ocean education and non-participating groups and to analyze the effectiveness of ocean education by developing measurement indicators for the value that individuals gave to ocean education services. To conduct this study, first, the value of ocean education was defined and value items that could be provided to individuals were classified. Second, to develop indicators that could measure classified value items, a Delphi survey was conducted to collect opinions of various experts. Third, by measuring the content validity ratio (CVR) for each item, final indicators and questionnaire were derived. As a result of Delphi analysis, 18 items with a CVR value of 0.6 or higher were finally adopted out of 32 indicator items. In the cognitive value category, indicators that could identify an individual's level of knowledge of the ocean, change in perception, and problem-solving ability were selected. In the behavioral value category, indicators were expanded to judge changes in attitudes and relationships toward the ocean and responsible behavior in more detail. This study is meaningful in that it provides the basis for directly judging the value of ocean education service provided by the government to the people. Results of such analysis are expected to contribute to securing a stable budget and the justification for expanding human resources in the government's continuous promotion of ocean education policies.

Development of Construction Manager's Competency Evaluation Index Using Sports Analysis Techniques - Focused on Notational Analysis - (스포츠 분석 기법을 활용한 건설관리자 역량 평가지표 개발 - 부호화 분석을 중심으로 -)

  • Lee, Jinsol;Park, Moonseo;Lee, Hyeon-soo;Cho, Jongwoo;Yoon, Inseok
    • Korean Journal of Construction Engineering and Management
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    • v.20 no.4
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    • pp.34-45
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    • 2019
  • To drive construction project successful, a construction manager with good competency is needed. In order to select appropriate construction manager, there should be a standard and a method for appropriately evaluating the competency of construction manager. There have been many researches on the competency of construction managers, but there are two points to be supplemented. One is that construction manager's competency measurement was not concrete and objective, and the other is that construction project performance directly reflects individual manager's performance. The purpose of this study is to derive a construction manager competency evaluation index by using the Notational Analysis technique that is used when deriving an indicator that measures the athlete's competency in sports. This analysis was drawn with Delphi method. Finally, the 'measurable behaviors'were derived that can evaluate the competency of construction managers. Through this, it is possible to express each manager's expertise, leadership, and personal characteristics in numerical expression. This will help decision makers when selecting construction managers. It is anticipated that decision makers will be able to make the decision to select the necessary construction managers easier because it can evaluate the construction managers through a scientific approach based on the record by supplementing the existing method which only relied on intuition.

The Value of the Good Faith of the Occupier for Acquiring the Right of Ownership by Limitation of Possession

  • Guyvan, Petro
    • International Journal of Computer Science & Network Security
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    • v.22 no.7
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    • pp.57-64
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    • 2022
  • This scientific article is devoted to the study of the legal significance of such a category of legal status of the purchaser of another's thing, as its good faith. The essence of this phenomenon has been studied, it has been established that the criterion of good faith attaches significant importance to the claims of the participants of these relations for the acquisition or preservation of private property rights. The paper emphasizes that, in addition to the importance of good conscience at the time of possession of another's thing, which gives legal certainty the possibility of registration of the title and is part of the actual composition for the acquisition of property or the right of ancient possession, bona fides also characterizes the behavior of the occupier. In this case, good conscience only has some legal consequences when it is opposed to subjective law. Under such conditions, it acquires direct legal significance, including as a condition for the acquisition and protection of rights. Good faith possession of another's property is an internal indicator of the subject's awareness of a certain property status. This sense, the article assesses this status from the standpoint of the scientific concept of the visibility of law. According to this theory, prescription is also considered as a consequence of the appearance of law, however, because it arises and lasts against the will of the parties and despite their awareness of this fact. Therefore, bona fide continuous and open possession of property as one's own, during the acquisition period, was most significantly associated with the appearance of property. Therefore, the concept of good faith, in the sense of personal perception of real values, is closely related to the principle of protection of the appearance of law, as it is aimed at understanding it by third parties. The paper notes certain differences in the application of the theory of the appearance of the right in the acquisition of property by a bona fide purchaser from an unauthorized alienator and the acquisitive prescription. It is emphasized that such a mechanism must be used in presuming the attitude to the thing as its own, by the holder of movable property. But there should be exceptions to the rule, in particular, if the owner has grounds for vindication of the thing.

Diagnosis-Specific Analysis of Small Area Variations in Hospital Services (일부 다빈도 진단명들의 지역간 의료이용 변이)

  • 이선희;조우현;남정모;김석일
    • Health Policy and Management
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    • v.4 no.1
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    • pp.49-76
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    • 1994
  • Small area variations in health care utilization have long been studied as an important issue related to boto cost containment and quality assurance. This study was conducted to investigate if variations in hospital services across small geographic areas in Korea existed. The claims data of the fiscal year 1992 obtained from the regional health insurance societies were used for the study. Main findings of the research can be summarized as follows : 1. Extremal Quotients(EQ) of hospital expenditure per capita and hospital days per capita varied among diagnosis types. The EQ ranged from 2.05(cataract) to 41.67(pneumonia) in hospital expenditure per capita and from 1.86(cataract) to 45.89(pneumonia) in hospital days per capita. The diagnosis groups which showed high variation were pneumonia, cephalo-pelvic disproportion, gastritis and duodenitis, fracture of rib, and acute bronchitis. Those which showed low variation were acute appendicitis and cataract. 2. The EQ level of admission rate was different in terms of diagnosis types, ranging from 2.57(catarct) to 44.45(pneumonia). The variations were high in medical disorders such as pneumonia, oephalo-pelvic disproportion, gastritis and duodenitis and acute bronchitis, while relatively low in surgical conditions such as acute appendicitis and cataract. 3. As an indicator of service intensity, the EQ of expenditure per admission ranged from 1.67(acute appendicitis) to 31.27(essential hypertension). The diagnoses which had high variation were essential hypertension, gastric ulcer, whereas those which had low variation were cephalopelvic disproportion and acute appendicitis. With regard to hospital days per admission, the EQ ranged from 1.55(acute appendicitis) to 28.13(gastric ulcer) by diagnosis types. The diagnosis groups with showed high variation were gastric ulcer, essential hypertension, and acute bronchitis, whereas those with low variation were cephalo-pelvic disproportion, intervertebral disc disorders, and acute appendicitis. Both the expenditure and hospital days per admission showed lewwer variations than the expenditure per capita, hospital days per capita and admission rate. 4. Comparing patterns of variation in utilization indices, diagnoses such as essential hypertension, gastric ulcer, fracture of rib showed higher variations in expenditure per admission than in admission rates, whereas diagnoses such as pneumonia, cephalo-pelvic disproportion and gastric ulcer showed higher variations in admission rate than expenditure per admission. These findings suggest that wide variations existed in several diagnoses groups across small areas in Korea. Further research should be performed to investigate factors related to small area variations including provider behavior.

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Factor Analysis on Psychological Cause of Speed Reduction in Expressway Tunnel Section Utilizing Importance-Performance Analysis (IPA) (고속도로 터널부 속도 감소에 관한 심리적 요인분석)

  • Lee, Ki Young;Kim, Tae Ho
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.2D
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    • pp.127-134
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    • 2010
  • Tunnel sections on the highway are different from rest of sections on the highway in terms of velocity, the number of passing cars, and vehicle density which, in particular, affect drivers' behavior before and after drivers pass through the tunnel. However, literature review reveals that former studies are too focused on quantitative indicator to consider qualitative aspects. Therefore, this paper conducts survey questionnaire and IPA (Importance Performance Analysis) to find out qualitative improvements on velocity drop on the tunnel sections. The results show as follows: First, drivers require improvements of tunnel form (length and curved form inside tunnel) which is derived from long distance tunnel. Second, experts primarily ask for amendment of geometric characteristics. With comparison of requirements of both drivers and experts, there are many differences in length of tunnel and form of curved tunnel. This also presents that drivers don't satisfy with both length of tunnel and form of curved tunnel that are provided as a part of highway design factors.

A Study on the Relationship between Health Equity and Subjective Health Status of Adolescents (청소년의 건강 형평성과 주관적 건강상태와의 관계 연구)

  • Kyung-Shin Paek
    • Journal of the Korean Applied Science and Technology
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    • v.39 no.6
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    • pp.864-873
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    • 2022
  • The subjective health status of adolescence reflects one's overall socio-emotional function and is an important factor in determining the health-related quality of life during this period. This study was to identify the correlation between subjective health status and health equity of adolescents. Data from the 16th online survey of youth health behavior (2020) was used to analyze 39,987 adolescents. Health equity was used as indicator for residential areas, economic conditions perceived by students, household abundance, family type, and parental education. Subjective health status was classified as a healthy group("very healthy", "healthy") and unhealthy group("normal", "unhealthy", and "very unhealthy") in response to the question "how do you think your health is usually?" The data were analyzed using complex sample analysis by using SPSS/Win 22.0. Significant factors related to the subjective health status of subjects were the area of residence (OR=0.86, p=.031), economic level (OR=1.33-2.09, p<.001), and family type (OR=1.24, p=.033). The economic level perceived by adolescents was the most important variable related to the subjective health status of adolescents, and adolescents from multicultural families often perceived their health as unhealthy compared to adolescents from general families. Therefore, there is a need for continuous interest in adolescents with low economic levels and adolescents from multicultural families and specific strategies to improve their health status.

Factors Affecting Social Capital Awareness of Social economy (사회적 자본이 사회적경제 인식에 영향을 미치는 요인)

  • Kuk-Gwen Lee;Seon-Gyeong Park
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.6
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    • pp.827-831
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    • 2023
  • This study sought to verify and examine the factors that influence social capital on social economy awareness. To summarize the results of the study, the results are as follows. As a result of analyzing the impact of social capital on social economy awareness, norms (t=3.228, p<.01) and participation (t=3.057, p<.01) had a significant impact on social economy awareness. In other words, the better the norms are observed and the higher the participation, the more influence it has on social economy awareness. Based on these results, the following implications were drawn. First, 'norms' refer to rules or standards that community members must adhere to within society, and these norms play a role in regulating the behavior of individuals and promoting social cooperation. Through this, it is believed that a strong normative system can have a significant impact on the way people participate or cooperate in social economy activities. Second, 'participation' is an indicator of how actively an individual or group participates in social activities. People with high levels of participation through social capital will have a high level of understanding of social economy awareness and will be able to act effectively. These results show that in previous studies, the better the norms were observed and the more trust and networks were strengthened, the higher the awareness of social economy. In contrast, in this study, norms and trust were found to have an effect, but the network did not, showing a difference from the results of previous studies, so repeated research is expected to be necessary in the future. Considering the results above, strengthening and developing the elements of social capital such as norms and participation can have a positive impact on overall socioeconomic awareness and development.

Analysis of the Mediating and Moderating Effects of Body Mass Index and Subjective Body Shape Perception on the Relationship Between Physical Activity and Self-Rated Health in Adolescents (청소년의 신체활동과 주관적 건강 인식 관계에서 체질량지수와 주관적 체형 인식의 매개효과와 조절효과 분석)

  • Jung-Hyun Yun;Mi-Na Jin;Chang-Jin Lee
    • Journal of Industrial Convergence
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    • v.22 no.5
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    • pp.79-88
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    • 2024
  • The study aim was to investigate the relationship between adolescents' physical activity and subjective health perceptions and determine whether body mass index (BMI), an obesity-related indicator, had a mediating or moderating effect on this relationship. To achieve the purpose of this study, raw data from the 18th Youth Health Behavior Online Survey (2022) were used, and data from 23,612 people were ultimately selected for the research analysis. A confirmatory factor analysis and structural equation modeling were applied to the data, and bootstrapping techniques were used to verify the mediating effect. To verify the moderating effect, a multigroup analysis of the structural equation model was applied to calculate pairwise parameter comparison values. All statistical significance levels were set at .05. The results of this study follow. First, the greater the amount of physical activity among adolescents, the more positive was the effect on subjective health perception. Second, subjective body type perception had a partial mediating effect on the relationship between physical activity and subjective health perception. Third, subjective body type had a moderating effect on physical activity and subjective health perception. Specifically, people who perceived their subjective body types as average viewed their subjective health more positively when they engaged in more physical activity than those who perceived their body types as slightly or very overweight. In conclusion, preventing obesity and positively changing the subjective health status through sufficient physical activity during adolescence are important.

Understanding ESG Management and the Possibility of ESG Archives (ESG 경영의 이해와 ESG 아카이브의 가능성)

  • Lim, JongChul
    • The Korean Journal of Archival Studies
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    • no.79
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    • pp.33-82
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    • 2024
  • Interest in ESG management, which spread through the UN PRI in 2006, has recently spread throughout our society. Consumers use a company's activeness in the ESG field as the standard of consumption behavior, and the international community is reorganizing and strengthening various regulatory measures. In the investment market, non-financial performance (ESG information) is used as an important investment indicator along with financial performance (credit rating). Due to these changes in the corporate evaluation paradigm and market pressure, if a company neglects ESG response activities, it is more likely to be excluded from market selection, and accordingly, the importance of ESG management is also increasing. Companies are making various efforts to secure legitimacy in response to these market pressures, but in the process, it is difficult to systematically manage and utilize records/data that are the basis for ESG management. For a basic understanding of ESG management, this paper summarizes the emerging process of ESG and the current ESG-related regulations applied to companies. Through this, it can be seen that ESG management is not carried out with the good will of the company, but is accepted as a management strategy for the survival of the company according to the change in the corporate evaluation paradigm. Through interviews with the company's ESG-related personnel, the company's ESG response process was divided into passive communication and active communication, and the problems identified during the interview were summarized for each communication type. In addition, in the process of passively and actively communicating ESG management information with internal and external stakeholders, the possibility that ESG archives can function as a tool to overcome problems for each communication type was raised, and five types of ESG archives that can play this role were presented.