• Clinical Nutrition Research
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• 제11권2호
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• pp.98-109
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• 2022

Irritable bowel syndrome (IBS) is a common disorder that affects the large intestine. Oxidative stress and inflammation play a major role in IBS. Considering the antioxidant properties of ellagic acid (EA), this study was designed to evaluate the effect of EA on oxidative stress index, inflammatory markers, and quality of life in patients with IBS. This research was conducted as a randomized, double-blind, placebo-controlled clinical trial; 44 patients with IBS were recruited. Patients who met the inclusion criteria were randomly allocated to consume a capsule containing 180 mg of EA per day (n = 22) or a placebo (n = 22) for 8 weeks. Serum levels of total antioxidant capacity (TAC), malondialdehyde (MDA), C-reactive protein (CRP), and interleukin-6 (IL-6) were measured at the beginning and the end of the study. Also, quality of life was assessed using a self-report questionnaire for IBS patients (IBS-QOL). At the end of the study, we saw a significant decrease and increase in the MDA and TAC in the intervention group, respectively (p < 0.05). Also, EA consumption reduced CRP and IL-6 levels, and these changes were significant in comparison with placebo group changes (p < 0.05). The overall score of IBS-QOL significantly decreased, and quality of life was increased (p < 0.05), but there were no significant changes in the placebo group. According to these findings, receiving polyphenols, such as EA, may help maintain intestinal health by modulating inflammation and oxidative stress and ultimately improving the quality of life in IBS patients.

• Journal of Applied Biological Chemistry
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• 제59권3호
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• pp.227-231
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• 2016

Deep sea water (DSW) is located 100 to 500 m below the sea surface. DSW is widely used in various fields, and is an important source of minerals that can be used to treat mineral deficiency. In the present study, the oral toxicity of DSW-mineral extracts was determined using single-dose and 14-day repeated dose oral toxicity tests in ICR mice. For the single-dose oral toxicity tests, mineral extracts of magnesium (Mg) and calcium (Ca) at doses of 0, 6, 270, 810, and 1,350 mg/kg, respectively, were orally administered to mice once at the beginning of the experiment, and the mice were observed for 14 days. For the 14-day repeated dose oral toxicity tests, Mg and Ca mineral extracts at doses of 0, 3, 135, 405, 675 mg/kg, respectively, were orally administered to mice daily, and the mice were observed for 14 days. Various tests were performed including visual observation; analysis of relative organ weight, food intake, and organ weight; biochemical analysis, and histopathology. The results indicated that mortality and changes in appearance were not observed among differentially administered groups of male and female ICR mice during the experimental period. Differences in body weight gain, food intake, organ weight, and histopathology parameters were not significant between the control and mineral-administered groups. Some results of the biochemical analyses were significantly different, but showed no specific tendencies. Overall, no evidence of toxicity was observed from the oral administration of DSW extracts of Ca and Mg in ICR mice.

• 대한가정학회지
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• 제50권8호
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• pp.79-95
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• 2012

The purpose of this study is to seek improvement in clothing life education through a development and application of the clothing life education program for middle schools based on the education and experience in arts & culture. On the basis of art & culture education as well as, Dewey's experience, the clothing life area education program was designed and developed for the 2nd year students in the middle school. This program was applied to 350 students of 9 2nd year classes in M middle school during the 17 periods of clothing life area classes, beginning from May 23rd, 2011 and lasting to September 30th, 2011. The leaner-evaluation was performed in terms of the level of learning interest and academic achievement. To measure the level of academic achievement, a mind-map evaluation was performed and a learning effect survey, which evaluates the level of achievement of learning objectives, was carried out. For the purpose of class observation, classes were filmed and analyzed. Characteristics of a class were recorded on a teacher's diary and was used to support the qualitative evaluation. According to the results, the education program is analyzed as being helpful and useful in student understanding of fiber, textile and, clothes, which are materials and outcomes of culture and art; moreover, they have a historical, cultural and artistic value in themselves. It is also analyzed as being helpful for the development of student aesthetic sensibility and emotion, for the construction of meaningful experience through a learning process, for the improvement of learning interest and the level of academic achievement, and for the positive recognition of the learning effect.

• 한국해양공학회지
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• 제26권2호
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• pp.58-67
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• 2012

Recently, both the integration of product data during design and production and the effective management of information during full lifecycles have attracted attention from shipyards and ship owners as a result of recycling regulations and a desire for efficient operations. Generally, PLM (Product Lifecycle Management) supports a collaborative environment during the BOL (Beginning of Life) stage, while an ALM (Asset Lifecycle Management) system provides all of the information required to maintain, overhaul, and discard/recycle all or part of a vessel during the MOL (Middle of Life) and EOL (End of Life) stages. The main goal of this paper is to suggest the fundamental configuration of a PALM (Product Asset Lifecylce Management) system and a method that can be used to utilize a marine vessel's lifecycle information during the MOL, emphasizing the maintenance information during the middle of life. The authors also suggest a PALM system configuration in which lifecycle information can be collected by a PEID (Product Embedded Information Device) integrating a microcomputer, sensors, and wireless network communication. Through a prototype PALM system, the suggested features and PALM system configuration are implemented.

• Journal of Korean Biological Nursing Science
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• 제18권4호
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• pp.296-304
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• 2016

Objective: The purpose of this study was to explore the effects of a senior functional game (Rejuvenescent village) on cognitive function, instrumental activities of daily living (IADL), depression, and life satisfaction in Korea. Methods: An one-group pretest-posttest design was used in this study. Data were collected twice (at the beginning and the end) from 100 elderly adults in S city who played "Rejuvenescent village" 8 times (twice per week, one hour per session) for a month. Also they completed questionnaires on their cognitive function, IADL, depression, life satisfaction, and general characteristics. The data were analyzed using SPSS 20.0 programs. Results: The mean age was 70.06(${\pm}3.77$) years, with a range of 65-80 years old. Among 100 subjects, 21% were male and 85% were young old. There were statistically significant differences in cognitive function (t=-3.32, p=.001), IADL (t=1.98, p=.049), and life satisfaction (t=-2.15, p=.034). Although there was no statistically significant difference in mean depression score (t=1.06, p=.292), categorized depression was statistically significant (${\chi}^2=62.97$, p<.001). Conclusion: The findings in this study show that the serious game (Rejuvenescent village) was effective for older Koreans' cognitive function, IADL, depression, and life satisfaction. Thus, we need to consider senior functional games to get health benefits by making elderly adults active with enjoyment.

• 한국융합학회논문지
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• 제13권3호
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• pp.217-225
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• 2022

본 연구는 2020년부터 코로나 바이러스의 영향을 받고 있는 인도 손해보험시장의 효율성과 생산성을 분석하였다. 비모수적 연구방법인 자료포락분석(DEA)을 사용하여 FY2013년부터 FY2019년까지 인도에서 건강보험 상품을 판매하고 있는 손해보험회사들을 표본으로 하였다. 분석 결과는 다음과 같다. 첫째, 전체 보험산업의 평균 효율성은 표본기간 동안 효율성이 감소하다가 개선되는 결과를 보여주었다. 둘째, 효율성 측정치를 그룹별로 살펴보면 민영보험회사가 효율성이 가장 높았으며 국영보험회사와 순수건강전문보험회사가 그 뒤를 따르고 있었다. 셋째, 연평균 생산성을 측정한 결과 전통적인 대면채널보다 텔레마케팅을 포함한 비대면채널을 운영한 보험회사의 연평균 생산성 증가율이 더 높은 것으로 파악되었다. 따라서 코로나 바이러스의 창궐로 인하여 비대면영업환경이 주를 이루는 가운데 향후 인도 손해보험회사는 영업전략 수립 시 비대면채널의 발전에 자원과 노력을 집중해야 할 것으로 보인다. 더불어 본 연구의 분석을 코로나 바이러스 창궐 이후 기간에 적용하는 것도 흥미로워 보인다.

• 디지털융복합연구
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• 제11권11호
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• pp.471-478
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• 2013

이 연구는 군인의 여가활동 유형에 따른 군대생활만족도를 경로분석 모형을 통하여 분석하였다. 조사대상은 경기도 북부, 남부지역의 두 부대에서 군 생활을 하고 있는 장병들을 대상으로 2011년 9월부터 8주 동안 해당부대를 직접 방문하여 설문 실시하였으며, 856부의 설문지를 회수하여 분석에 사용하였다. 연구 결과 군인들의 생활만족도에는 신체증상, 우울, 사회적 지지가 유의하게 영향을 미치는 관련요인으로 밝혀졌으며, 본 연구를 토대로 군은 군인의 신체증상과 우울을 완화시키고 사회적 지지 체계의 구축에 효과적인 여가활동을 통해 군인들의 생활만족도를 향상시킬 수 있도록 제도적인 뒷받침이 있어야 할 것이다.

• International Journal of Computer Science & Network Security
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• 제24권5호
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• pp.172-180
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• 2024

Since the beginning of 2015, corporate social responsibility (CSR) models have been changing in connection with the trend towards the transition of joint value creation of corporate activities and consideration of stakeholders' interests. The purpose of the academic paper lies in empirically studying the current practice of social responsibility of transnational corporations (TNCs). The research methodology has combined the method of qualitative analysis, the method of cases of agricultural holdings in emerging markets within the framework of resource theory, institutional theory and stakeholders' theory. The results show that the practice of CSR is integrated into the strategy of sustainable development of TNCs, which determine the methods, techniques and forms of communication, as well as areas of stakeholders' responsibility. The internal practice of CSR is aimed at developing norms and standards of moral behaviour with stakeholders in order to maximize economic and social goals. Economic goals are focused not only on making a profit, but also on minimizing costs due to the potential risks of corruption, fraud, conflict of interest. The system of corporate social responsibility of modern TNCs is clearly regulated by internal documents that define the list of interested parties and stakeholders, their areas of responsibility, greatly simplifying the processes of cooperation and responsibility. As a result, corporations form their own internal institutional environment. Ethical norms help to avoid the risks of opportunistic behaviour of personnel, conflicts of interest, cases of bribery, corruption, and fraud. The theoretical value of the research lies in supplementing the theory of CSR in the context of the importance of a complex, systematic approach to integrating the theory of resources, institutional theory, theory of stakeholders in the development of strategies for sustainable development of TNCs, the practice of corporate governance and social responsibility.

• 한국의사학회지
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• 제31권1호
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• pp.23-42
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• 2018

This study examines the variation in diagrams of the kidney, and the effects on location of the Life Gate as a result. My study analyzes diagrams of kidney form and location, such as appearance, the vertebral spine, ShenXi, and "Life Gate", and also explores the causes for such variations. The kidney is commonly described as having the shape of a bean, which throughout medical history has showed almost no variation. The spine was initially described with a total of 21 vertebrae, and later with a range of 19-25 vertebrae. Regarding the height of kidney in relationship to the spine, it was initially described as beginning at the 14th vertebrae, and later changed to the 15th or 17th vertebrae. However, there have been no changes in the perception of the height of kidney. Initially, the location of the Life Gate could not be identified. Three different suggestions of its location were found throughout historical literature, including: (1) at or within the right kidney; (2) between two kidneys; and (3) between 14th-15th spine. There were also variations noted in the process of copying diagrams of kidney in many books not only because the work of copying was not precise, but also because each medical practitioner had a different interpretation of the kidney's form and function in Traditional Korean and Chinese Medicine. It appears that some practitioners may have been influenced by their understandings of theory of Life Gate.

• Journal of Ginseng Research
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• 제43권2호
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• pp.252-260
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• 2019

Background: Increases in the average global temperature cause heat stress-induced disorders by disrupting homeostasis. Excessive heat stress triggers an imbalance in the immune system; thus protection against heat stress is important to maintain immune homeostasis. Korean ginseng (Panax ginseng Meyer) has been used as a herbal medicine and displays beneficial biological properties. Methods: We investigated the protective effects of Korean ginseng extracts (KGEs) against heat stress in a rat model. Following acclimatization for 1 week, rats were housed at room temperature for 2 weeks and then exposed to heat stress ($40^{\circ}C$/2 h/day) for 4 weeks. Rats were treated with three KGEs from the beginning of the second week to the end of the experiment. Results: Heat stress dramatically increased secretion of inflammatory factors, and this was significantly reduced in the KGE-treated groups. Levels of inflammatory factors such as heat shock protein 70, interleukin 6, inducible nitric oxide synthase, and tumor necrosis factor-alpha were increased in the spleen and muscle upon heat stress. KGEs inhibited these increases by down-regulating heat shock protein 70 and the associated nuclear $factor-{\kappa}B$ and mitogen-activated protein kinase signaling pathways. Consequently, KGEs suppressed activation of T-cells and B-cells. Conclusion: KGEs suppress the immune response upon heat stress and decrease the production of inflammatory cytokines in muscle and spleen. We suggest that KGEs protect against heat stress by inhibiting inflammation and maintaining immune homeostasis.