• Journal of Pharmaceutical Investigation
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• v.30 no.1
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• pp.47-50
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• 2000

A new technique has been developed for the preparation of Lactobacillus microcapsules to enhance the stability against high temperature, humidity, gastric acid and bile acid. Employing fluidized bed coating, primary sub-coating was processed in non-organic solvent system, so that Lactobacillus did not directly contact with organic solvent. Secondary enteric-coating was processed in organic solvent with low temperature $(below\;33^{\circ}C)$ technique, which minimized the heat labilability of Lactobacillus. Survival rate of Lactobacillus within microcapsule was not less than 95% and acid tolerance was above 30% in the artificial gastric acid. Further more it was dissolved in the artificial intestine juice within 2-3 hr. Average size of Lactobacillus microcapsules was $450\;{\mu}m$(25-50 mesh) and its viability was above 90% in the direct tableting.

• KSBB Journal
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• v.9 no.5
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• pp.525-531
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• 1994

Tyrosinase has two types of enzymatic activities, cresolase catalyzing the hydroxylation of monophenol and catecholase catalyzing the oxidation of o-phenol. Gradual inactivation of the enzyme during the reaction is a barrier to be overcome for the commercial application of the enzyme. Tyrosinase was stabilized by modifying the lysine residue of the enzyme using glutaraldehyde. In addition to that, tyrosinase was also stabilized by adapting the continuous reactor system. In packed bed reactor quinone could be easily removed, so the stability of tyrosinase increased. Borate buffer retarded the reaction rate of catechol to quinone and consequently decreased the tyroslnase inactivation. Tyrosinase immobilizer on controlled pore glass showed significantly enhanced stability in a packed-bed reactor.

• Geomechanics and Engineering
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• v.25 no.1
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• pp.49-58
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• 2021

The resistance of soil to the tractive force of flowing water is one of the essential parameters for the stability of the soil when directly exposed to the movement of water such as in rivers and ocean beds. Biopolymers, which are new to sustainable geotechnical engineering practices, are known to enhance the mechanical properties of soil. This study addresses the surface erosion resistance of river-sand treated with several biopolymers that originated from micro-organisms, plants, and dairy products. We used a state-of-the-art erosion function apparatus with P-wave reflection monitoring. Experimental results have shown that biopolymers significantly improve the erosion resistance of soil surfaces. Specifically, the critical shear stress (i.e., the minimum shear stress needed to detach individual soil grains) of biopolymer-treated soils increased by 2 to 500 times. The erodibility coefficient (i.e., the rate of increase in erodibility as the shear stress increases) decreased following biopolymer treatment from 1 × 10-2 to 1 × 10-6 times compared to that of untreated river-sands. The scour prediction calculated using the SRICOS-EFA program has shown that a height of 14 m of an untreated surface is eroded during the ten years flow of the Nakdong River, while biopolymer treatment reduced this height to less than 2.5 m. The result of this study has demonstrated the possibility of cross-linked biopolymers for river-bed stabilization agents.

• Journal of radiological science and technology
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• v.42 no.3
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• pp.195-199
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• 2019

Most of the vascular procedures performed for various diagnoses and treatments of various abdominal intervention procedures performed by the Department of Radiology and Angiography are performed by puncture of the femoral artery. For this reason, patients should undergo blood-related tests such as prothrombin time (PT) and partial thromboplatin time (PTT). Therefore, many patients are instructed to take precautions such as putting a sandbag on the puncture site to prevent delayed hemorrhage after hemostasis of the femoral artery puncture site, and not to bend the leg of the treated area for about 3 hours. Because of this, many patients have complained of pain during the procedure and inconvenience during the absolute bed rest time in the ward. The purpose of this study was to compare the safety of balloon ancillary devices with sandbags placed on the hemostasis site to prevent delayed hemorrhage after arterial puncture. We compared the safety of each patient with the results of medical records in consideration of the problem that the patient could not press with the focus, the position of the patient was changed depending on the patient's body shape, and the problem of falling down according to the location of the puncture site. As a result, the use of a balloon type ancillary device improves the effect of continuous hemostasis, reduces discomfort during the patient's absolute stabilization time, increases the patient's satisfaction, and is a good alternative to the existing sandbag.

• Journal of Korea Soil Environment Society
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• v.5 no.2
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• pp.99-105
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• 2000

The purpose of this study was to show the application of the Biofilter for treatment of the soil contaminated by lead and to investigates the effect of the biofilter on the retardation of lead with pilotplants that were simulated with different media and the number of bed. and to testify the inoculation by seeding microbes. The ratio of the degradation of soil contaminant was verified as CODcr/TOC in order to find a variation of the stabilization index in soil. The Biofiltration was one of biological processing methods for treatment. The contaminants were transported through the biofilter that was filled with the media. The surface of media formed biofilm which was surrounded by microbes and through its boundary, some materials were exchanged and migrated into the cell of microbes in an orderly manner. To investigate the effect of the Biofiltration, contaminated soil with lead nitrate of 1000mg/kg in dry was made artificially. The tests were simulated such as compost, Bioceramic and compost with bioceramic by 7:3 in weight. The bed consisted of three layers in order to find effect of the number of bed. Aspergillus niger was used as a biosorbent could probe the effect on the retardation of lead.

• Proceedings of the Korean Geotechical Society Conference
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• 1992.10a
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• pp.137-144
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• 1992

This paper reports a case study of dynamic consolidation. The objective of the study is to evaluate the effectiveness of ground improvement at the site for Hyundai Petrochemical Compound constructed at Daesan-Myeon, Seosan-Gun in the western shores of Korea. The site ground was prepared by filling on the existing soft marine deposit which consists of a loose granular soil layer and a medium stiff clay layer. For the stabilization of site ground, the compaction was executed in three different procedures with same pounder weigh, drop height and imprint spacing. The post investigation showed that the object was successfully achieved indicating a significant increase of bearing capacity of the treated ground. In this study the effectiveness of dynamic consolidation is evluated for various factors the applied energy, temping sequences, the radial distance from the imprint location and the depth of bed rock.

• Explosives and Blasting
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• v.21 no.3
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• pp.23-35
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• 2003

An analytical diffusion model for flood routing with backwater effects and lateral flows is developed. The basic diffusion equation is linearized about an average depth of (H + h), and is solved using the boundary conditons which take into account the effects of backwater and lateral flows. Scouring phenomenon around pier which affects on the support function of pier and the stabilization if river bed is a complex problem depending on flow properties and river bed state as well as pier geometry. therefore, there is no uniting theory at present which would enable the designer to estimate, with confidence, the depth of scour at bridge piers. The various methods used in erosion control are collectively called upstream engineering, HEC-RAS Model, underwater blasting. They consist of reforestation, check-dam construction, planting of burned-over areas, contour plowing and regulation of crop and grazing practices. Also included are measures for proper treatment of high embankments and cuts and stabilization of streambanks by planting or by revetment construction. One phase of reforestation that may be applied near a reservoir is planting of vegetation screens. Such screens, planted on the flats adjacent to the normal stream channel at the head of a reservoir, reduce the velocity of silt-laden storm inflows that inundate these areas. This stilling action causes extensive deposition to occur before the silt reaches the main cavity of the reservoir.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.12
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• pp.659-667
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• 2017

This study analyzes the changes in the flow characteristics due to the difference in inflow discharges from the main channel and tributary at the confluence of the Nakdong and Geumho Rivers. The analysis was done using a two-dimensional numerical method. The study site has complicated flow patterns because of the discharge variation from the main stream and tributary. The study section has a meandering main channel, and the hydraulic characteristics cannot be defined with simple conditions such as the confluence angle of the channels or the ratio of the channel widths. An actual flood event in 2012 was applied in the numerical simulation. The maximum velocity occurred in the meandering section after passing the confluence, where a rapid change was expected. A high velocity and large bed change in this section were observed in the simulation results. The variation of discharges from the main channel and tributary was a more dominant factor in the flow and bed changes for the normal flow conditions than the flood event. This indicates that countermeasures for channel stabilization should be considered in the meandering section downstream of the confluence section, and countermeasures for the study section should be investigated.

• Smart Structures and Systems
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• v.17 no.3
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• pp.363-389
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• 2016

Deficient modes that cannot be always identified from different sets of measurement data may exist in the application of operational modal analysis such as the stochastic subspace identification techniques in large-scale civil structures. Based on a recent work using the long-term ambient vibration measurements from an instrumented cable-stayed bridge under different wind excitation conditions, a benchmark problem is launched by taking the same bridge as a test bed to further intensify the exploration of mode identifiability. For systematically assessing this benchmark problem, a recently developed SSI algorithm based on an alternative stabilization diagram and a hierarchical sifting process is extended and applied in this research to investigate several sets of known and blind monitoring data. The evaluation of delicately selected cases clearly distinguishes the effect of traffic excitation on the identifiability of the targeted deficient mode from the effect of wind excitation. An additional upper limit for the vertical acceleration amplitude at deck, mainly induced by the passing traffic, is subsequently suggested to supplement the previously determined lower limit for the wind speed. Careful inspection on the shape vector of the deficient mode under different excitation conditions leads to the postulation that this mode is actually induced by the motion of the central tower. The analysis incorporating the tower measurements solidly verifies this postulation by yielding the prevailing components at the tower locations in the extended mode shape vector. Moreover, it is also confirmed that this mode can be stably identified under all the circumstances with the addition of tower measurements. An important lesson learned from this discovery is that the problem of mode identifiability usually comes from the lack of proper measurements at the right locations.

• Journal of Navigation and Port Research
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• v.36 no.8
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• pp.659-664
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• 2012

Coastal vegetaion consists of rooted flowering marine plants that provide a variety of ecosystem services to the coastal areas they colonize. The attenuation of waves and sediments stabilization are often listed among these services. From this point of view, artificial vegetation model is an effective method of controlling sea bed and stabilization without damaging the landscape or the stability of the coastaline. In this study, numerical and hydraulic physical test for predicting deposition proces of a navigation channel caused by wave action is proposed. In the numerical model, we develop a numerical model for describing the wave attenuation and sediment transport in a navigation channel with a vegetation area. In addition, hydraulic model tests is performed in a navigation channel with irregular waves to examine the effect of vegetation in relation to deposition reduction in navigation channel. A comparison between the results of hydraulic and numerical tests shows resonable agreement.