• Title/Summary/Keyword: Basic Research Status

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A Case Study on the Evaluation of Environmental Health Status Focused on Multiple Impact and Environmental Justice (다중 영향 및 환경정의를 고려한 지역 환경보건수준 평가 사례연구)

  • Park, Choong-hee;Han, Hye-ji;Lee, Young-mee;Yoo, Si-eun;Jung, Da-young;Chu, Yeon-hee
    • Journal of Environmental Health Sciences
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    • v.46 no.1
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    • pp.22-34
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    • 2020
  • Objectives: Based on the concept of environmental justice, we developed an evaluation model for setting and adopting the direction of environmental health policy using environmental health indicators and statistics from the local governments of Seoul, including environmentally susceptible populations. Methods: We selected a total of 20 variables based on data officially released from national and local governments. After the classification of these variables into the five components of environmental pressure, environmental status, environmental disease, sensitive population, and socioeconomic status, a basic model was constructed to calculate the relative scores of the local governments. Results: The cumulative impact scores for assessment of environmental health status were similar to those of the environmental pressure and status components. The highest five cumulative impact scores fell between 114 and 147. Local government A reported the highest scores and had high environmental pressure, environmental status and socioeconomic status. In addition, the evaluation of the other four local governments indicated that they exhibited above average scores for environmental pressure and environmental status, two did so for environmental disease, and four for sensitive population. Conclusion: We constructed a model to evaluate the environmental health status of the local governments of Seoul based on cumulative impact scores under the concept of environmental justice. As an approach for studying environmentally vulnerable areas through relative ranking, this model was feasible for policy-setting. In addition, this approach would be an analytically useful tool for decision-makers.

Status and Prospects of the Korean National Environmental Health Survey (KoNEHS) (국민환경보건기초조사의 현황 및 전망)

  • Park, Choonghee;Yu, Seung Do
    • Journal of Environmental Health Sciences
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    • v.40 no.1
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    • pp.1-9
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    • 2014
  • Objectives: The purpose of this review is to suggest future directions for the Korean Environmental Health Survey (KoNEHS) in terms of an environmental health monitoring system and recent environmental health issues in Korea. Methods: The national scale biomonitoring program and environmental health researches which conducted by Ministry of Environment was reviewed for this study. The scope, contents and utilization of results of KoNEHS as a biomonitoring program and other basic function for environmental health monitoring was analyzed. Results: Biomonitoring survey was conducted for basic functions, such as evaluating exposure levels of environmental chemicals and analyzing exposure factors. In order to expand the basic purposes of KoNEHS, the biomonitoring function should be strengthened by enlarging the range of chemicals analyzed and including all age groups in the biomonitoring and health status monitoring functions by using official health-care and mortality data. Exposure factors such as time-activity patterns and micro-environmental pollution levels were studied. The data from the environmental health study were established into a standardized database system for supporting environmental health policy. A definition and concept of environmental health services should be established. Conclusion: To achieve the aims of environmental health, changes in environmental health status and related factors must be observed and predicted reflecting real conditions. In this regard, improving the methodology and system through diverse approaches is necessary for KoNEHS.

A Study on the Policy Issues of Basic Research Promotion in Korean Academics (대학의 연구자 주도 기초연구에 대한 주요 정책 이슈 고찰)

  • Park, Kwisun;Kim, Haedo;Jang, Kyeongsu
    • Journal of Korea Technology Innovation Society
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    • v.21 no.3
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    • pp.938-968
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    • 2018
  • Korea's basic research has been rapidly expended in both quantative and qualitative aspect since establishment of 'the Korea Science & Engineering Foundation' in 1977, proclaiming of 'the First Year of Basic Research Promotion' and enactment of 'the Basic Sciences Promotion Act' in 1989. Despite the continuous increment of government basic research funding, the problem of low perceptions of university researchers on the funding increment has been constantly raised. Based on an intrinsic review on the core issues are diagnosed based on Korean academics' basic research status analysis and future challenges are proposed based on the precedent diagnoses. The six key issues that need to take the next step in Korean academics' basic research are as follows: (1) basic research investment in universities, (2) appropriate research expenses for supporting individual researcher, (3) basic research funding allocation method, (4) maintaining the sustainable success rate of research projects, (5) systematic and strategic support for excellent researchers, (6) creating research-immersive environment. The five challenges to promote basic research in academics are as follows: (1) increasing in university research expenses, (2) diversification of basic research funding allocation method, (3) establishment of research field-specified support system and predictable principles, (4) stable and sufficient support for outstanding researchers, (5) reducing burden on research administration.

Relationship between Sense of Belonging, Powerlessness and Nutritional status of Elderly People (노인의 소속감, 무력감과 영양 상태와의 관계)

  • Kim, Mi-Hye;Chung, Hae-Kyung
    • Journal of the Korean Society of Food Culture
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    • v.30 no.1
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    • pp.118-128
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    • 2015
  • This study was performed to analyze health problems in older adults in a comprehensive manner, including usual living habits, nutritional status, and society psychological factors. Research was conducted by a structured questionnaire by interviews with a test group of 316 people over the age of 65 from April 2012 to August 2012. Elderly people's dietary intake was assessed using NSI (Nutrition Screening Initiative) by the 24-hour retrospective method, and elderly people's feeling of helplessness and sense of belonging were assessed using the measuring device. Material analysis, descriptive statistics, and regression analysis were performed using SPSS. Elderly people with increased age showed higher chances of being in the high-risk and undernourished group. Elderly with high NSI showed low intake of fat, protein, fibrin, vitamin C, E, $B_1$, $B_2$, Niacin, K, Fe, Zn, and Cu than those with low NSI. Findings from this comparative analysis indicate that elderly with better nutritional status showed a lower feeling of helplessness than those with poor nutritional status. Overall, elderly people consumed a b road variety of foods, and social emotional stability of elderly people increased at optimal dietary levels.

Sarcoma Immunotherapy: Confronting Present Hurdles and Unveiling Upcoming Opportunities

  • Sehan Jeong;Sharmin Afroz;Donghyun Kang;Jeonghwan Noh;Jooyeon Suh;June Hyuk Kim;Hye Jin You;Hyun Guy Kang;Yi-Jun Kim;Jin-Hong Kim
    • Molecules and Cells
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    • v.46 no.10
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    • pp.579-588
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    • 2023
  • Sarcomas are rare and heterogeneous mesenchymal neoplasms originating from the bone or soft tissues, which pose significant treatment challenges. The current standard treatment for sarcomas consists of surgical resection, often combined with chemo- and radiotherapy; however, local recurrence and metastasis remain significant concerns. Although immunotherapy has demonstrated promise in improving long-term survival rates for certain cancers, sarcomas are generally considered to be relatively less immunogenic than other tumors, presenting substantial challenges for effective immunotherapy. In this review, we examine the possible opportunities for sarcoma immunotherapy, noting cancer testis antigens expressed in sarcomas. We then cover the current status of immunotherapies in sarcomas, including progress in cancer vaccines, immune checkpoint inhibitors, and adoptive cellular therapy and their potential in combating these tumors. Furthermore, we discuss the limitations of immunotherapies in sarcomas, including a low tumor mutation burden and immunosuppressive tumor microenvironment, and explore potential strategies to tackle the immunosuppressive barriers in therapeutic interventions, shedding light on the development of effective and personalized treatments for sarcomas. Overall, this review provides a comprehensive overview of the current status and potential of immunotherapies in sarcoma treatment, highlighting the challenges and opportunities for developing effective therapies to improve the outcomes of patients with these rare malignancies.

Present Status and Prospect of Researches on Laryngopharyngeal Reflux (인후두역류 관련 연구의 현황 및 전망)

  • Choi, Seung-Ho
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.18 no.2
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    • pp.113-117
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    • 2007
  • Although the prevalence of laryngopharyngeal reflux (LPR) is presumed to be very high, basic researches on LPR have not been active so far. This is a review of present status and prospect of researches on LPR to help readers' understanding of current trend on LPR research. In vitro and in vivo researches on acid/pepsin, intercellular junctions, bile juice, carbonic anhydrase, cytokines, and Helicobacter pylori were discussed. Considering that quality of life is getting more important in accordance with longer life span and that a fair proportion of LPR patients do not respond to conventional therapy, researches on pathogenesis and pathophysiology of treatment measures are necessary and it is anticipated for more and more researchers to concern themselves in basic research on LPR in the future.

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The Effect of Maslow's Basic Needs on the Clothing Values among Adult Women (Maslow의 기본욕구가 의복가치관에 미치는 영향)

  • Kang Kyung-Ja;Suh Young-Sook
    • Journal of the Korean Society of Clothing and Textiles
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    • v.13 no.1 s.29
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    • pp.1-12
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    • 1989
  • The purpose of this study was to examine the effect of basic needs and demographic variables of adult women upon clothing values. This study was designed with causal model regrading the demographic variables as independent variable: the basic need as interventing variable: the eight clothing values as dependent variables. The major findings of this research can be summarized as following; 1. Age of women has a definite effect on marriage status, school career and income. Age has effect on marriage status in seven values except exploratory value. It has effect on school career in aethetic and political values, and it has also effect on school career and income in social and religious values. 2. Age has no significant direct effect on the basic needs. Marriage status and school career have significant direct effect on the basic needs. Marriage status has positive effect on the need for self-esteem in seven values except exploratory value. The need for self-esteem of unmarried women are stronger than that of married women. School career has negative impact on the need for safety. The women having higher school career do not have strong need for safety in aethetic and social values. 3. School career, income, needs for safety, belongingness, self-esteem and self-actualizing have significant direct effect on clothing values. School career has positive effect on aethetic and political values, and it has negative effect on religious values. Income has negative effect upon social and religious values. Need for safety has negative effect on aethetic values. Need for safety is positively related with need for belongingneses, and they have an effect on the social values. Need for self-esteem has positive effect on the aethetic and political values, and it has negative impact on theoretical, economic, social and religious values. Need for self-actualizing has positive effect on the theoretical values.

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Current Status of Internal Dosimetry Methods and Radiological Regulations in Korea, Ukraine and European Community

  • Lee, Tae-Young;Lee, Jong-Il;Berkovski, Vladimir
    • Journal of Radiation Protection and Research
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    • v.28 no.1
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    • pp.65-73
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    • 2003
  • The paper discusses results of recent international intercomparison exercises on internal dose assessments, status of up to date internal dosimetry methods and the radiological legislation developed and implemented in Korea, European Union and Ukraine. The system of radiation protection in Korea is based on the Korean Atomic Energy Regulatory Enforcement on Safety Standards (Ministry Notice No. 2001-2). The notice is based on the recommendations in ICRP Publication 60 (1990) and IAEA Basic Safety Standards (1996). But the full implementation of the notice by the end of the year 2002 is not required because of the socio-economic situation and inexperience in internal radiation dosimetry Regulatory framework for internal radiation dosimetry is under development toward the full implementation of the notice from January 1, 2003. The system of radiation protection in Ukraine is based on the National radiation protection regulatory code NRBU-97. The code was developed and adopted in 1998 and replaced the Regulations of Former Soviet Union. The document is based on the ICRP Publication 60, Euratom Directive 96/29 and IAEA Basic Safety Standards (1996). The transitional period of 5 years (effected till January 2003) is established for implementation of all requirements of this new regulation. The system of radiation protection in the European Community is based on the Council Directive 96/29/Euratom, adopted in 1996 and enforced from 13 May 2000. Directive 96/29/Euratom has the status of the European law.

Current Status and Future Research Directions in Supply Chain Management (공급사슬경영 연구의 현황 및 향후 연구 방향)

  • Kim, Sook-Han;Lee, Young-Hee
    • IE interfaces
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    • v.13 no.3
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    • pp.288-295
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    • 2000
  • As the industrial environment becomes more competitive, supply chain management(SCM) has become recognized as a major strategy in the business world. Despite its current widespread popularity, its basic concepts are confused with those of other exiting logistic tools and not clearly understood. This paper introduces the current status of SCM in terms of physical logistics, interrelationship with other logistic tools as well as the general history and definitions of SCM. Researches are categorized into deterministic models, stochastic models, simulation models, and several future research areas are discussed in this paper.

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The study on the Skythian Costume I - Focaused on the Scythian of the northern region of the Black Sea - (스키타이 의복에 대한 연구 I - 흑해 북쪽 지역 스키타이인을 중심으로 -)

  • Yi-Chang, Youngsoo
    • Fashion & Textile Research Journal
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    • v.17 no.2
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    • pp.191-202
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    • 2015
  • The purpose of this study is to examine the form of the clothing of the Scythians who lived in the northern region of the Black Sea. This study refers to data, which has been extracted from reviews of literature, articles and catalogs of Scythian exhibitions held in Germany, a country where famous Scythian research was collected and analyzed. Results of this study are as follows: Regarding the basic form, there was no change in the appearance of the Scythian clothes which can be linked to social classes and regional background. But the detailing of the clothes changed. Russian archaeologist Klocko has stated that decorative bands of ancient costume appear to depend on the construction of ancient clothing. I have analyzed the upperjacket of Scythians with the decorative bands based on the research of Klocko. From this analysis could be observed that decorative bands of upperjacket had also been varied depending on their region and their social status. The decoration of the revers of upperjacket differs according to social status. According to their width, trousers were classified in types; in narrow and wide. The basic set up of the narrow-type is as follows: the trouser is divided into voluminous straight forms and leggings in close contact with the legs. The width of a trouser differs according to the social status of Scythians and from the region where they lived. Regional differences could be observed more significantly, than differences resulting from social status.