• Women's Health Nursing
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• v.6 no.1
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• pp.96-108
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• 2000

The purpose of this study was to provide the basic data for developing a program for effective education about GDM(Gestational Diabetes Mellitus) by investigating the knowledge and learning needs of pregnant women about GDM. The subjects were 192 pregnant women who visited obstetrical clinics for prenatal care. The data were collected from October, 1998 to December, 1999, using a 50-item questionnaire(knowledge ; 30 items, learning needs ; 20 items), and analyzed by SAS program for t-test, ANOVA, Ducan test, and Pearson correlation coefficients. The results were as follows. 1. The knowledge level about GDM 1) Pregnant women had very little knowledge(total means ; 15.1 of 30.0) about GDM. 2) Pregnant women more than 30 years old, pregnant women from Seoul, and pregnant women who had more than a bachelor's degree were more knowledgeable about GDM. 3) Pregnant women who didn't experience spontaneous abortions, pregnant women who had DM(Diabetes Mellitus) patients in their families, and pregnant women who received education about DM were more knowledgeable about GDM. 4) Pregnant women knew very well that GDM women have more maternal and fetal complications than normal pregnant women. Although they were knowledgeable about the importance and ways of controlling blood glucose level, they knew very little about the causes, symptoms, or management of hypoglycemia. 2. The learning needs about GDM 1) Pregnant women had high learning needs (total means ; 85.0 of 100.0) about GDM. 2) The learning needs of pregnant women who had more than a bachelor's degree and pregnant women who earned less than two million won in monthly income were higher than that of other groups. 3) Pregnant women had high learning needs about the health of their baby and themselves, but their learning needs related to weight control and exercise-things that play important roles in controlling blood glucose level-were relatively low. As a result of the above findings, a systemic and individualized program is required for pregnant women and GDM patients, In addition to that, further studies that investigate the effects of education and retention of learning obtained by education are required in the near future.

• Journal of Ginseng Research
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• v.44 no.3
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• pp.461-474
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• 2020

Background: Ginseng effectively reduces fatigue in both animal models and clinical trials. However, the mechanism of action is not completely understood, and its molecular targets remain largely unknown. Methods: By screening for proteins that interact with the primary components of ginseng (ginsenosides) in an affinity chromatography assay, we have identified muscle-type creatine kinase (CK-MM) as a potential target in skeletal muscle tissues. Results: Biolayer interferometry analysis showed that ginsenoside metabolites, instead of parent ginsenosides, had direct interaction with recombinant human CK-MM. Subsequently, 20(S)-protopanaxadiol (PPD), which is a ginsenoside metabolite and displayed the strongest interaction with CK-MM in the study, was selected as a representative to confirm direct binding and its biological importance. Biolayer interferometry kinetics analysis and isothermal titration calorimetry assay demonstrated that PPD specifically bound to human CK-MM. Moreover, the mutation of key amino acids predicted by molecular docking decreased the affinity between PPD and CK-MM. The direct binding activated CK-MM activity in vitro and in vivo, which increased the levels of tissue phosphocreatine and strengthened the function of the creatine kinase/phosphocreatine system in skeletal muscle, thus buffering cellular ATP, delaying exercise-induced lactate accumulation, and improving exercise performance in mice. Conclusion: Our results suggest a cellular target and an initiating molecular event by which ginseng reduces fatigue. All these findings indicate PPD as a small molecular activator of CK-MM, which can help in further developing better CK-MM activators based on the dammarane-type triterpenoid structure.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.9 no.10
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• pp.407-421
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• 2019

The purpose of this study was to survey the knowledge and practice about preventive behavior for urinary tract infection in caregivers, and ultimately to provide the basic information in terms of urinary tract infection prevention. Participants in this study were caregivers who working at the 7 long-term care facilities in J-city of South Korea. Total 198 were participated in this study. Descriptive statistics, t-test, one-way ANOVA, and scheffe test were performed using SPSS Windows for 21.0 program. The correct answer rate for the knowledge about preventive behavior of urinary tract infection was 79%. The practice of urinary tract infection preventive behavior were significantly differed by the number of nurses, the number of elderly, working time and the experience, perceived importancy, necessity with education for urinary tract infection. The preventive behavior for urinary tract infection in caregivers should be supervised by health care providers. Moreover, it should be needed to educate and apply the basic education program to improve the caregivers' knowledge and practice for preventive behavior in urinary tract infection by healthcare providers. Continuous infection monitor and education by healthcare providers can be contributed the quality of elderly caring services and development of monitoring system for urinary tract infection in long-term care facilities.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.1 no.1
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• pp.85-97
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• 1995

Orthopaedic medicine was developed and published by James Cyriax, a British Orthopaedic Physician on 1929. Orthopaedic medicine is concerned with the diagnosis and treatment of soft tissue lesions. These disorders affect a substantial proportion of all patients in general and in particular, physiotherapy and sports clinics. In broad terms these disorders em trace conditions. such as arthritis. rheumatism. fibrositis. backache. lumbago, sciatica, frozen shoulder, tennis elbow, strained wrist, sprains, aches, inflanmation and sports injuries generally. The soft Moving tissues share one thing in common - they are all radiotranslucent and the tissues in question are the joint capsule, the ligaments, the fasciae, dural sheath. These structures can cause pain but none of them is visible on the radiograph. Dr. Cyriax divided all soft tissues into two basic types : 1) Contractile tissue, 2) Inert or noncontractile tissue. The mechanism of diagnosis is tension applied manually. The physician subjects each tissue about the incriminated joint to tension in turn which they call 'Selective tension' with Cyriax's assessment, a more definitive diagnosis can be obtained and proper treatment can be implemented.

• The Journal of Korean Society for School & Community Health Education
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• v.10 no.1
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• pp.35-46
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• 2009

Background & Objectives: The purpose of this study was to offer basic materials for the correct comprehension of dementia and of health education needs by comparing the students' recognition level of dementia. Methods: Three health major departments(the department of nursing science, physical therapy and occupational therapy) and three non-health major departments(the department of English, early childhood education and biology) were randomized in universities. And the 180 juniors students involved in this study and their level of educational experience and of recognition of dementia was analyzed. Results: There weas no difference about recognition of social welfare services between the students of health departments and non-health departments, but there were differences between them about other health education needs. Conclusion: Students of non-health majors who learn the subjects unrelated to dementia should get an education on dementia so that they can understand and recognize health education needs on dementia.

• Journal of muscle and joint health
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• v.11 no.2
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• pp.176-186
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• 2004

Purpose: The purpose this research was to provide with basic data in the control of the sleep disorder found in the patients with fibromyalgia by analysing the main factors that affect that. Method: At two university medical center, appointed 171 out-patients diagnosed of fibromyalgia according to the conditions by American College of Rheumatology(1990). The research instruments used in this study were VAS Scale(Anxiety, fatigue, pain, joint stiffness and depression), physical activity family support, the number of tender points and Self-efficacy scale. In data analysis, SPSS 11.0 program was utilized and data were analyzed using descriptive statistics, Pearson's correlation coefficient and multiple regression. Result: The main factors that affect the sleep disorder of patients with fibromyalgia were fatigue, physical activity, and depressions which explained 46.2% of the sleep disorder. Conclusion: It has been confirmed that the regression equation model of this research may serve as a sleep disorder prediction factors in patients with fibromyalgia.

• Korean Journal of Health Education and Promotion
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• v.28 no.3
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• pp.17-29
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• 2011

Objectives: This study was to explore how elderly with chronic disease in a health management program managed their health and to describe their health management strategies. Methods: The data were collected through in-depth interviews, with a purposeful sample of twelve in an urban community. The collected information was analyzed through grounded theory approaches by Strauss and Corbin. Results: Though open coding process, 35 concepts, 17 subcategories, 8 categories were identified. As for the participation experience process, four stages had surfaced, namely, 'Perception of chronic disease', 'Concerned about health', 'Developing life pattern', 'Restoring health'. These processes were within 'Restoring Health Equilibrium', core category. Consequently, the participants revealed in restoring relationship-oriented life and settling in family-focused life. Conclusions: These findings have implications for the understanding of health promotion for the elderly with chronic diseases and contributing to make a basic data for developing elderly health management program.

• Journal of muscle and joint health
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• v.2 no.2
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• pp.160-167
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• 1995

An aquatic exercise program is one of the nursing intervention for the patients having rheumatoid arthritis. The purpose of this study was to obtain the effect of aquatic exercise program on depression and helplessness in the rheumatoid arthritis patients. Thirty five patients with rheumatoid arthritis were the subjects of this study. who were treated to the rheumatism center at a hospital in Seoul from December 1992 to April 1993. The data were collected before and after aguatic excercise. All data collected were analyzed using percent, t-test, ANCOVA with SPSS $pc^+$ program. The findings of this study were as follows : 1. The score of depression was not different between experimental group and control group(P=0.178). 2. There was significant difference in the helplessness score between experimental group and control group(F=4.60, P=0.039).

• International Journal of Contents
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• v.17 no.1
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• pp.54-60
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• 2021

The aim of this study was to identify factors influencing problem drinking among the Echo Generation in South Korea and provide basic data for early intervention and mediation of problem drinking among the Echo Generation. This descriptive study performed a secondary analysis of raw data from the 2018 Korean National Health and Nutrition Examination Survey and used responses for problem drinking items from 999 Echo Generation participants born between 1979 and 1992. This study comprehensively investigated sociodemographic and health-related factors influencing problem drinking among the Echo Generation. SPSS WIN program (version 26.0) was used for data analysis. Gender (β=-.32, p<.001), education level (β=.10, p=.002), white-collar workers out of job (β=-.09, p=.041), and depression (β=.11, p<.001) were identified as factors that influenced problem drinking among the Echo Generation. Results of this study suggest that in order to prevent problem drinking among the Echo Generation, there should be user-customized prevention education and intervention programs.

• Biomedical Science Letters
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• v.13 no.2
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• pp.119-125
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• 2007

It is widely known that protein tyrosine kinases (PTKs) are involved in controlling many biological processes such as cell growth, differentiation, proliferation, survival and apoptosis. An $\alpha3\beta4$ subunit combination acts as a major functional acetylcholine receptor (nAChRs) in male rat major pelvic ganglion (MPG) neurons, and their activation induces fast inward currents and intracellular calcium increases. Recently it has been reported that the activity of acetylcholine receptors (AChRs) in some neurons can be negatively regulated by PTKs. However, the exact mechanism of regulation of nAChRs by PTKs is poorly understood. Therefore, we examined the potential role particular in nAChR by PTK using electrophysiology and calcium imaging in male rat MPG neurons. ACh induced inward currents and $(Ca^{2+})_i$ increases in MPG neurons, concomitantly. These responses were inhibited by more than 90% in $Na^+$- or $Ca^{2+}$- free solution. $\alpha$-conotoxin AuIB, a selective $\alpha3\beta4$ nAChR blocket, inhibited ACh-induced inward currents. Genistein (10 $\mu$M), a broad-spectrum tyrosine kinase inhibitor, markedly decreased ACh-induced currents and $Ca^{2+}$ transients, whereas 10 $\mu$M genistin, an inactive analogue, had little effect. Overall these data suggest that the activities of $\alpha3\beta4$ AChRs in MPG neurons are positively regulated by PTK. In conclusion, trosine kinase may be one of the key factors in the regulation of $\alpha3\beta4$ nAChRs in rat MPG neurons, which may play an important roles in the autonomic neuronal function such as synaptic transmission, autonomic reflex, and neuronal plasticity.