• Title/Summary/Keyword: Basic Medicine

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Fiberscopic and Electromyograpic Study on Laryngeal Adjustments for Syllable-final Applosives in Korean (한국어의 음절말 내파음의 후두조절 -화이비스코프 및 근전도에 의한 관찰-)

  • Park, Hea-Suk
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.16 no.1
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    • pp.53-67
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    • 2005
  • It is known that Korean stop consonants in syllable-initial position are of three types : lax, aspirated and forced (or unaspirated). In syllable-final position, however, these three different types are merged to a single type with the same place of articulation, although the original three-way distinction is preserved in Korean orthographic (Hangul) system. Thus the syllable-final stops are phonetically realized as voiceless "applosives" which are characterized by the absence of oral release. The aim of the present study is to investigate the laryngeal adjustments for these syllable-final stops in various phonological conditions by using fiberscope, and, is to further investigate electromyographically the laryngeal adjustments for Korean stops both in the syllable-initial and final positions in various phonological conditions. The results can be summarized as follows : 1. In the case of syllable-initial stops, the glottal widths in each three types of the Korean stops during the articulatory closure are clearly different. And the pattern of thyroarytenoid(VOC) activity appeared to characterize the three different types of Korean stops. 2. The basic laryngeal feature of the Korean syllable-final applosives is characterized by a small degree of glottal opening which begins at or slightly after the oral closure. 3. In the case, syllable-final stop followed by the copula "ita", the syllable- final stop is pronounced as the stop consonant at the initial position of the following syllable containing the vowel[i], the underlying features of three-way distinction for the stops in the Korean orthographic(Hangul) system being manifested at the laryngeal adjustment. 4. In the case of the final applosives followed by the initial stops and fricatives, the laryngeal feature of the final applosives appears to be assimilated by that of the following consonant irrespective of the difference in the place of articulation, as far as the glottal abduction/adduction is concerned. It is clearly demonstrated in the case of syllable-initial stop that thyoarytenoid(VOC) activity is suppressed for the production of the stop consonants in question, the degree of which is slightest for the forced type and most marked for the aspirated type, while it is moderate for the lax type.

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Virtual Reality in Cognitive Rehabilitation (인지재활 영역에서 가상현실)

  • Park, Inn-Jee;Park, Heung-Seok;Kim, Tae-Hoon
    • Therapeutic Science for Rehabilitation
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    • v.1 no.1
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    • pp.29-38
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    • 2012
  • Introduction : This study reviews the main areas of cognitive rehabilitation including executive dysfunction, memory dysfunction, perceptual dysfunction, attention deficit, and dysfunctions in activities of daily living in order to apply to the adaptation of occupational therapy. Body : Cognition programs based on the virtual reality are being used not only to evaluate but to train the overall components of human's cognition. Because the cognitive program is concentrating on the real environment, it is known to bring a remarkable transitional effect to the actual environment, compared to the basic computer-based evaluation and training. Applying virtual reality to the rehabilitation program can develop and advance the high technology and can result in a major effect on the innovative treatment technology. Conclusions : In this process, virtual reality is expected to be researched more in the near future. Particularly in the cognitive realm, it is imperative for researchers to pay attention to the improved transitional effect of the virtual reality toward the actual environment, rather than the already existing method of evaluations. Therefore, application of the virtual reality for the cognitive training should be researched for various types of subjects in the diverse aspects of congnitive function. Application of the virtual reality in the cognitive function has its unlimited potential, thus the rehabilitation program integrated with not only evaluation but training and education is expected extensively in the future.

Genetic variation of halophyte New Zealand spinach (Tetragonia tetragonioides) accessions collected in Korea using an AFLP marker (AFLP 마커를 이용한 국내수집 염생식물 번행초 유전다양성 평가)

  • Jeon, Yongsam;Jin, Yong-Tae;Choi, Seo-Hee;Park, Nuri;Kim, In-Kyung;Lee, Ka Youn;Choi, Jong-Jin;Lee, Geung-Joo
    • Journal of Plant Biotechnology
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    • v.43 no.2
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    • pp.157-163
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    • 2016
  • This study was conducted to investigate the potential use of New Zealand spinach (Tetragonia tetragonioides) as a new vegetable crop which will be cultivated in salt-affected soils such as reclaimed areas. New Zealand spinach ecotypes native to Korea were collected across the Southern, Western and Eastern seashore regions of the Korean peninsula, among which fifty-five accessions were later further propagated and evaluated genetically by using an AFLP (amplified fragment length polymorphism) marker. Based on the AFLP analysis performed to uncover the genetic diversity of the collected ecotypes, enzymatic cleavage of the extracted DNA was implemented based on 12 EcoRI and MseI combinations. A total of 1,279 alleles (107 alleles per EcoRI and MseI enzyme combination) were successfully amplified, among which 62 alleles per enzyme combination were polymorphic (58%). The AFLP analysis indicated that the rate of genetic dissimilarity was 29% among the New Zealand spinach collections, which were clustered into the 7 genetic diversity group. This is the first report on the genetic variation in the genus Tetragonia, and the basic information can be applied to select parental lines for enhancing the segregation spectrum of the new halophytic vegetable plant grown in salt-affected areas.

Mismatch Negativity Using Frequency Difference in Healthy Young Adults: Latency and Amplitude (건강하고 젊은 성인에서 주파수 차이를 이용한 불일치음전위: 잠복기와 전위)

  • Jung, Seokwon;Kim, Young-Soo;Yang, Tae-Won;Kim, Do-Hyung;Kim, Min Su;Bae, Sang Hyeon;Kim, Ga-In;Kwon, Oh-Young
    • Korean Journal of Clinical Laboratory Science
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    • v.52 no.3
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    • pp.194-201
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    • 2020
  • Latency and amplitude are the measurement parameters of mismatch negativity (MMN). The values of the parameters vary sensitively with the stimulus paradigm. A paradigm using the frequency difference of sounds for the MMN study is well known. This study obtained the reference values of the parameters in healthy young adults by performing the MMN study using the frequency paradigm. The authors recruited ten healthy adults. Their average age was 25.5 years; three were female, and seven were male. On the auditory paradigm for the MMN study, the frequency of sound was 1000 Hz for the standard stimulus, and 1032 Hz for the deviant stimulus. The mean values of latency and amplitude of MMN were 202 ms and 1.88 ㎶ at Fz, 207 ms, and 1.46 ㎶ at Cz, 212 ms, and 1.10 ㎶ at C3, and 214 ms and 1.45 ㎶ at C4. There was no correlation between the latency and amplitude of MMN. This study presented the reference values of the latency and amplitude of the MMN using a standard paradigm that is easy to apply. This information may make the MMN useful for clinical applications and basic research.

Studies on AIDS(Acquired Immune Defficiency Syndrome) Preventive Educational Programs Intended for Domestic and Foreign Industrial Workers (국내외 산업장 근로자의 AIDS(Acquired Immune Deficiency Syndrome)예방교육을 위한 소고)

  • Jung Moon-Hee;Cho Chung Min
    • Journal of Korean Public Health Nursing
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    • v.10 no.1
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    • pp.12-22
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    • 1996
  • Currently. exchanges of industrial workers between countries are more active than ever. and the problem of AIDS in connection with the operation of preventive educational programs has reached a point where the issue cannot be limited to native people alone any more. Based on such judgement. this research has been carried out to provide basic study materials by grasping the latent factors representing the difference between countries in the levels of right knowledge. attitude and behavior with respect to AIDS maintained by workers who have grown in different social and cultural living background. During the period from Apr. 1. 1995 to Jun. 30. questionnaires. written both in Korean and English, were distributed to Korean and Malaysian employees working at certain Korean video manufacturers. and the results of replies. given by 80 workers who were analyzed through matched sampling· method where ages and sex matched by country. were used as the research materials. The gathered materials were analyzed through the SPSS package t-test. ANOVA. factor analysis and multiple stepwise regression methods. and the following results were obtained. 1. The 2 extracted latent factors could be named 'common. social' knowledge factor and 'in-depth. psychological' knowledge factor respectively. 2. The percentile points of 'external. social' knowledge factor. in the case of Korean workers. howed 90.0 at average. a figure 13.75 points higher than those of Malaysian workers. 76.25. On the other hand. the percentile points of the 'in-depth. psychological'knowledge factor showed 70.80 at average in the case of Korean workers. a figure 7.47 points lower than those of Malaysian workers. 78.33. Meanwhile. the difference in percentile points between the 2 latent factors was 8.54 at average. indicating that the points of 'in-depth. psychological' knowledge factor was lower than those of the 'external. social' knowledge factor. 3. As for Korean workers. the percentile points of the 'in-depth. psychological' knowledge factor showed higher points in office workers than in non-office workers. and such variables exhibited in the position of workers can explain the $7\%$ of the latent factor. The percentile points of the 'in-depth. psychological' knowledge factors. in the case of Malaysian workers. showed higher points in groups who had religion than in groups who did not. and higher points in groups who obtained information from newspapers than in groups who obtained from televisions or other sources; and with these 2 variables. $26\%$ of this latent factor can be explained. The results. of analysis described so far suggest that while Korean workers possessed general level of knowledge on AIDS. they had low level of practical knowledge as far as its depth is concerned. and that they had social prejudice on patients as well as on the AIDS infection route. In addition. because the overall knowledge level of Malaysian workers. is lower than that of Korean workers. it suggests that separate programs intended for Malaysian workers are required prior to executing integrated programs.

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A Study of Resuscitation in Victims in Out-of-hospital Cardiac Arrests (병원전 심정지환자의 심폐소생술 성적)

  • Kang, Byung-Woo
    • The Korean Journal of Emergency Medical Services
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    • v.8 no.1
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    • pp.149-160
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    • 2004
  • Background : To save out-of-hospital cardiac arrest cases is a major concern for Korea. Cardiac arrest is a very common problem, with > 18,000 cases dying each year in Korea. Overall, survival to hospital discharge remains poor. Resuscitation has become an important multidisciplinary branch of medicine, demanding a spectrum of skills and attracting a plethora of specialities and organizations. Since the "Utstein Style" was advocated in 1991, many reports about out-of-hospital cardiac arrest have been published based on this guideline. These differences prevent valid inter-hospital and international comparisons. However, we do not know the true effectiveness of resuscitation. There are no guideline for reviewing, reporting, conducting research on resuscitation in Korea. This study evaluated the out-of-hospital factor associated with survival discharge of out-of-hospital cardiac arrest, was especially to provide basic data for the unified reporting guideline of resuscitation in Korea. Methods : From January 1990 to July 2004, we collected data about out-of-hospital cardiac arrest at Wonju Christian Hospital(WCH-CAD), Ewha Women University Mokdong Hospital(Ewha-CAD), I used same record form based on the "Utstein Style". The "Utstein Style" is internationally recommended guidelines for reporting outcome data from resuscitation events. Results : Resuscitation was performed in 1443 out-of-hospital cardiac arrest patients at 2 hospitals. Five hundred eighty(40.25%) patients recovered the spontaneous circulation at least once and One hundred sixty eight(11.66%) patients discharged alive. Initial EKG showed Ventricular Tachycardia/Ventricular Fibrillation in One hundred thirty five(9.33%) patients, asystole in one thousand nine(69.73%) patients and other rhythms in one hundred thirty nine(20.94%) patients. Among one hundred two cardiogenic cardiac arrest patients, two(2.0%) patients was discharged alive. Conclusion : Overall survival rate of out-of-hospital cardiac arrest patients was 11.66% which was poorer than that of the western country. The proportion of the cardiogenic cause was 33.38% which was only half of the western country. VT/VF is relatively not common ac a initial EKG rhythm. These differences might be to due difference in the prevalence pattern of out-of-hospital cardiac arrest as well as prematurity of the EMSS. It is needed that the best survival can be achieved if all following links have been optimized : rapid access, early CPR, early defibrillation, early ACLS.

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Changes of Characteristics of Patients in Daily Regional Emergency Room after Execution of Five-day Workweek System (주 5일제 시행 후 일 지역 응급실 환자 특성 변화)

  • Choi, Gil-Soon;Kwon, Hay-Rran
    • The Korean Journal of Emergency Medical Services
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    • v.11 no.1
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    • pp.53-64
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    • 2007
  • Purpose: Ths study aims to examine characteristics of patients using emergency room after execution of five-day workweek system by government and provide basic materials for operation of efficient emergency room. Methods: Data were collected tbrough medical records of patients visiting emergency room from July of 2004 to October of 2006 and they were analyzed with SPSSlPC 10.0. Conclusion : 1. The number of patients visiting emergency room was average 16.7 persons a day in 2004, 17.5 in 2005 and 18.6 in 2006 and it was found that it was increasing every year since the execution of five-day workweek system 2. Gender distribution of subjects using emergency room was higher in male than in female every year. 3. Means of transport to emergency room were mostly private car and others(public transport or on foot), but use of ambulance was increasing. 4. Residential areas of subjects were mostly 'Myeon area' in 2004~2005, but it was changed to residents at 'Eup area' in 2006. 5. Distribution of patients by medical departments was highest in internal medicine and surgery in 2004~2006 and rate of visiting pediatrics was increasing every year. 6. Time to stay at emergency room was most at 'below 30 min'. in 2004~2006, but cases of stay for 'more than 2 hours' were increasing every year. 7. On presence or absence of trauma in patients visiting emergency room, rate of visit to emergency room with 'no trauma' was higher and this result was increasing every year. 8. As a result of classifying severity of patients visiting emergency room, use rate of emergency room by 'non-emergency' patients was over 90% in 2004~2006 and such a phenomenon was deepened in 2006 compared to that in 2004. 9. Measures after emergency care of patients were most in case of 'discharge' in 2004~2006, but cases of admission to hospital after emergency care were increased every year. 10. According to use of emergency room by a day of the week, use on Sunday was most frequent in 2004~2006, but use on Friday the day before holiday was increasing. 11. According to distribution by age, use by those between '40~49' was most in 2004~2005, but use by those 'below 10' was most in 2006. 12. According to time to visit emergency room, using emergency room at "15:31~23:30 was most in 2004~2006, cases of visiting emergency room at day working hour were decreased every year and those at evening and night working hours were increased. Conclusion: In sum, it was found that characteristics of patients visiting emergency room and their actual status were changed after the execution of five-day workweek system and efforts to rearrange emergency medical system are required.

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Income Analysis on the Cultivation of Major Medicinal Herbs (주요 약초류 재배에 대한 소득분석)

  • Kang, Hag Mo;Chang, Cheol Su;Kim, Hyun;Choi, Soo Im
    • Journal of Korean Society of Forest Science
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    • v.104 no.3
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    • pp.495-502
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    • 2015
  • This study intended to provide basic data required in establishing policies for improving the forestry management and the compensation standard for the loss from non-timber forest products by examining the cost of cultivating key medicinal herbs and the earnings from them to analyze the income. According to the income analysis on the cultivation of medicinal herbs, the average annual income per unit area of Adenophora triphylla var. japonica Hara was the highest as it recorded 14,233,000 won/10a and was followed by Pleuropterus multiflorus TURCZ. which recorded 4,121,000 won/10a, Gastrodia elata Blume 3,766,000 won/10a, Epimedium koreanum Nakai 3,537,000 won/10a, Atractylodes ovata (Thunb.) DC. 2,655,000 won/10a, Aralia continentalis Kitagawat 1,048,000 won/10a, Paeonia lactiflora Pallas 1,025,000 won/10a, and Bupleurum falcatum L. 919,000 won/10a. Compared with the income from major nuts and fruits analyzed in 2014, the average annual income per unit area for medicinal herbs was relatively higher. For Adenophora triphylla var. japonica Hara and Aralia continentalis Kitagawat, soots are used for food and the roots for medicine, it appears that it can become a new income source for the farming and mountain villages. Meanwhile, the price for Paeonia lactiflora Pallas is dropping due to Chinese imports, and also damage to the income from other medicinal herbs due to Chinese imports is expected with the implementation of Korea-China FTA in the future.

Feeding Effect of an Anabolic Steroid, Nandrolone, on the Male Rat Testis

  • Lee, Dong-Mok;Min, Tae-Sun;Choi, In-Ho;Cheon, Yong-Pil;Chun, Tae-Hoon;Park, Chang-Sik;Lee, Ki-Ho
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.12
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    • pp.1566-1577
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    • 2010
  • Nandrolone, 19-nortestosterone, is a synthetic androgenic-anabolic steroid promoting muscle growth. Nandrolone is also present in pig meat and sera at non-negligible levels. A number of scientific reports have suggested a positive relationship between incidence of infertility and increased meat consumption in humans. The present study was designed to determine out the effect of feeding nandrolone on the testis of the male reproductive tract. Mixtures of food and nandrolone at different concentrations (0.005 ppm and 0.5 ppm) were supplied to pubertal male rats for 6 weeks. Body weight was recorded every week during the entire experimental period. At the end of the treatment, the testis, epididymis, and epididymal fat were collected and weighted. Sperm numbers in the caudal epididymis were counted. Differential gene or protein expression of steroidogenic enzymes in the testes among experimental groups was determined by semi-quantitative real-time PCR or western blotting analysis, respectively. Histological changes of the testis induced by nandrolone treatment were examined by hematoxylin and eosin staining. Immunohistochemical analysis was employed to detect changes in the localization of steroidogenic enzymes in the testes among experimental animals. There were no significant changes on body, testis, epididymis, and epididymal fat weights among experimental groups. A significant increase of caudal sperm number was found in the 0.5 ppm nandrolone-treated group. Histological examination of the testes noted a high frequency of germ cell sloughing in seminiferous tubules of 0.5 ppm nandrolone-treated rats. Even though transcript levels of $3{\beta}$-hydroxysteroid dehydrogenase (HSD) I, $17{\beta}$-HSD4, and $17{\alpha}$-hydroxylase were influenced by nandrolone treatments, protein levels of all molecules examined in the present study were not significantly affected. Immunohistochemical analysis showed no visible changes in the localization of steroidogenic enzymes in the testes among experimental groups. The current study showed that oral intake of nandrolone in male rats for 6 weeks did not cause significant damage to the testis. It is considered that a feeding effect of nandrolone on male fertility would not be remarkable.

Effect of Oral Administration of Intact Casein on Gastrointestinal Hormone Secretion and Pancreatic α-Amylase Activity in Korean Native Steer

  • Lee, S.B.;Choi, C.W.;Jin, Y.C.;Wang, T.;Lee, K.H.;Ku, M.B.;Hwang, J.H.;Kim, K.H.;Vega, R.S.A.;Lee, H.G.
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.5
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    • pp.654-660
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    • 2013
  • Three Korean native steers ($779{\pm}24$ kg) fitted with duodenal cannulas were used in a $3{\times}3$ Latin square design to investigate the influence of oral administration of soluble proteins, intact casein (IC) and acid hydrolyzed casein (AHC), on gastro-intestinal hormone (GIH) secretion in the blood and pancreatic ${\alpha}$-amylase activity in the duodenum. Oral treatment consisted of a basic diet (control), IC (C+100% protein), or AHC (C+80% amino acid, 20% peptide) for 21 d. Blood and duodenum samples were collected for measurement of serum GI hormones, and pancreatic ${\alpha}$-amylase activity was determined at 900, 1030, 1330, 1630, and 1930 h after feeding on d 21 of treatment. The levels of serum cholecystokinin (CCK) and secretin in the IC treatment group were higher compared to the other treatment groups (p<0.05). In addition to the changes in CCK and secretin levels upon IC treatment, the pancreatic ${\alpha}$-amylase activity in the duodenum was higher in the IC group compared to the control diet group (p<0.05). The response of serum ghrelin to IC and AHC treatment was in accordance with the response of serum secretin. The level of peptide fragments flowing in the duodenum was higher in the IC treatment group than the other treatment groups (p<0.05). In conclusion, this study demonstrated that an increase in duodenal CCK and secretin upon IC oral administration increased pancreatic ${\alpha}$-amylase secretion. In addition, ghrelin may be associated with GI hormone secretion in Korean native steers.